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The map label for this gene is amiC [H]

Identifier: 114797830

GI number: 114797830

Start: 839464

End: 840963

Strand: Reverse

Name: amiC [H]

Synonym: HNE_0817

Alternate gene names: 114797830

Gene position: 840963-839464 (Counterclockwise)

Preceding gene: 114799835

Following gene: 114799367

Centisome position: 22.7

GC content: 65.4

Gene sequence:

>1500_bases
ATGACCAGACTGACACGCCGTGCCGCCCTTGCCGGGGGCGCCGCCACCGTTGCCCTCGCCGCCTGCAACCCCAGGGCTTC
GGACACTGAACCGGCGGCAGACAGCGCGGTTGCGCCCGCAGGATTCCGGGACGGGGTTGCCATAGCGGCAGCAATTGAAG
CGGGGGAAACCACGGCGCTGGCCGAAGTGGAGGCAGCCATCGCGCGCGCCAGAGCCGTAGAAGAGGCGATCAACGGTATT
GTCACCGAGACCTTCGAGCTGGCACGGTCGGATGCGAGCGGTGTGCTCTCCGGCCCGTTTGCCGGCGTGCCGAGCTTCAT
CAAGGATCTGATCGACTGGCGCGGCGCGCCGACACTCAAGGGCAGCCGCGGGCTGCCGAAACAACTGGCCACTGCGGACA
ATCCCTTTGCCGCCAAATGGCGGGGTGCCGGCATTGTGTCGCTCGGAAAATCGGCCACGCCGGAAGCCGGGCTCATCTCT
TCTACCGAACCTCTCTCCAATGGACCAACCCGCAACCCCTGGGATCTGAGCCGCATACCTGGCGGTTCTTCGGGCGGCGC
GGCGGCATTGGTGGCGGCCCGCGTGGTGGCGTTTGCGCATGCCAGCGACGGGGGCGGATCAATCCGTATACCGGCATCGA
CCTGCGGGGTGTTTGGCATGAAGCCGTCTCGCGACCGGCTGCCTTACAGCGAACCGGGCGCAATACCCCCGCCATTGCAA
ATCTCGGTGAACCATGCCGTGACCCTCAGTGTGCGCGATTCCATTGCGCTGTTTCGCGCGGCAGAAGCGCTCGATGGCAC
CTATCCGGCGCTGGGGGAAATTCAGCCCCTGACACGGCGGTTGCGGATCGGCTTTGCGCCCGAACCGATTGGCGGGACGG
AGCTTCATCCCGATACGCGCGCCGCGCTTGAAGACGTGGCGCAGCTCTGCCGTGACCTTGGCCATACGGTGATCGATTAC
ACCATTCCGATGGACGGGCCGAAGTTCACGGATGCCTTCATTACCTATTGGGCTGCGGGCGCAGCGGATTTCGCGCGTCA
GGTGAGTGAAGCGTCGGGCAAGCCGATTGGTCCCGACATCGTGGAGCCCTGGACGCTGGGACTGGCAAACCTGGCGGCCT
CGCGCCTGACCGACCTGCCCGGCATCGTGGGATACCTGCTTGGCTTCGAGGAAGAGTATCACAGCTTCTTCAACGATCTG
GACATCCTGCTGACGCCCGTAACGGGCAGTCCGGCGGTTCCGGTTGGCGAACAGGCCCCGGACGGCGATTTCGACGCGGT
AATGGACAGCGTGCTGAAGTTTGTTGCCTACACCTCGCCGATGAACGTGGCGGGCGCCGCGTCCATGAGCGTGCCTCTGG
CCTGGTCACCTGCGGGCCTGCCGATCGGGGCGATGTTCTCCGGCCGTCGGGGAGATGACGCCCTAATGTTCGAGCTGGCA
CTCGAACTGGAAGCCGCCCGCCCCTGGGCGGATCGAAAGCCTCCGCTGTCTGCCCTGTAA

Upstream 100 bases:

>100_bases
GCCAGCACCGGTTTCACCCGAGACTTGCGCGCGAGCCCCTTGCCCGCCACGATACGTACTTCATCGGCCTTGAAAGGCCT
GAGTTCGGAGAGCTTCGTTG

Downstream 100 bases:

>100_bases
TATTCGCAAGAATTAATCAGTCAGATCAAGCAATTAACCAAAGTGTTCCCGTCCTTTGCAGGCTGGAAACGCCTCGTGTG
CTAGAAATCTTTTAGCACGA

Product: putative 6-aminohexanoate-cyclic-dimer hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTRLTRRAALAGGAATVALAACNPRASDTEPAADSAVAPAGFRDGVAIAAAIEAGETTALAEVEAAIARARAVEEAINGI
VTETFELARSDASGVLSGPFAGVPSFIKDLIDWRGAPTLKGSRGLPKQLATADNPFAAKWRGAGIVSLGKSATPEAGLIS
STEPLSNGPTRNPWDLSRIPGGSSGGAAALVAARVVAFAHASDGGGSIRIPASTCGVFGMKPSRDRLPYSEPGAIPPPLQ
ISVNHAVTLSVRDSIALFRAAEALDGTYPALGEIQPLTRRLRIGFAPEPIGGTELHPDTRAALEDVAQLCRDLGHTVIDY
TIPMDGPKFTDAFITYWAAGAADFARQVSEASGKPIGPDIVEPWTLGLANLAASRLTDLPGIVGYLLGFEEEYHSFFNDL
DILLTPVTGSPAVPVGEQAPDGDFDAVMDSVLKFVAYTSPMNVAGAASMSVPLAWSPAGLPIGAMFSGRRGDDALMFELA
LELEAARPWADRKPPLSAL

Sequences:

>Translated_499_residues
MTRLTRRAALAGGAATVALAACNPRASDTEPAADSAVAPAGFRDGVAIAAAIEAGETTALAEVEAAIARARAVEEAINGI
VTETFELARSDASGVLSGPFAGVPSFIKDLIDWRGAPTLKGSRGLPKQLATADNPFAAKWRGAGIVSLGKSATPEAGLIS
STEPLSNGPTRNPWDLSRIPGGSSGGAAALVAARVVAFAHASDGGGSIRIPASTCGVFGMKPSRDRLPYSEPGAIPPPLQ
ISVNHAVTLSVRDSIALFRAAEALDGTYPALGEIQPLTRRLRIGFAPEPIGGTELHPDTRAALEDVAQLCRDLGHTVIDY
TIPMDGPKFTDAFITYWAAGAADFARQVSEASGKPIGPDIVEPWTLGLANLAASRLTDLPGIVGYLLGFEEEYHSFFNDL
DILLTPVTGSPAVPVGEQAPDGDFDAVMDSVLKFVAYTSPMNVAGAASMSVPLAWSPAGLPIGAMFSGRRGDDALMFELA
LELEAARPWADRKPPLSAL
>Mature_498_residues
TRLTRRAALAGGAATVALAACNPRASDTEPAADSAVAPAGFRDGVAIAAAIEAGETTALAEVEAAIARARAVEEAINGIV
TETFELARSDASGVLSGPFAGVPSFIKDLIDWRGAPTLKGSRGLPKQLATADNPFAAKWRGAGIVSLGKSATPEAGLISS
TEPLSNGPTRNPWDLSRIPGGSSGGAAALVAARVVAFAHASDGGGSIRIPASTCGVFGMKPSRDRLPYSEPGAIPPPLQI
SVNHAVTLSVRDSIALFRAAEALDGTYPALGEIQPLTRRLRIGFAPEPIGGTELHPDTRAALEDVAQLCRDLGHTVIDYT
IPMDGPKFTDAFITYWAAGAADFARQVSEASGKPIGPDIVEPWTLGLANLAASRLTDLPGIVGYLLGFEEEYHSFFNDLD
ILLTPVTGSPAVPVGEQAPDGDFDAVMDSVLKFVAYTSPMNVAGAASMSVPLAWSPAGLPIGAMFSGRRGDDALMFELAL
ELEAARPWADRKPPLSAL

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=242, Percent_Identity=30.9917355371901, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI222831590, Length=501, Percent_Identity=23.75249500998, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17556264, Length=192, Percent_Identity=32.8125, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17543272, Length=465, Percent_Identity=27.0967741935484, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537465, Length=203, Percent_Identity=32.512315270936, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538252, Length=333, Percent_Identity=26.1261261261261, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17556276, Length=238, Percent_Identity=33.1932773109244, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556278, Length=238, Percent_Identity=33.1932773109244, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32565337, Length=363, Percent_Identity=25.6198347107438, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71990152, Length=300, Percent_Identity=25.6666666666667, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550774, Length=193, Percent_Identity=35.7512953367876, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24648435, Length=193, Percent_Identity=34.7150259067358, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24648437, Length=193, Percent_Identity=34.7150259067358, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24652985, Length=484, Percent_Identity=26.8595041322314, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19922090, Length=484, Percent_Identity=26.8595041322314, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24652981, Length=484, Percent_Identity=26.8595041322314, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24652983, Length=484, Percent_Identity=26.8595041322314, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644968, Length=208, Percent_Identity=32.6923076923077, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI161078093, Length=494, Percent_Identity=26.1133603238866, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356731, Length=195, Percent_Identity=31.7948717948718, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24648441, Length=125, Percent_Identity=39.2, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648439, Length=125, Percent_Identity=39.2, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648113, Length=437, Percent_Identity=26.5446224256293, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 51624; Mature: 51493

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLTRRAALAGGAATVALAACNPRASDTEPAADSAVAPAGFRDGVAIAAAIEAGETTAL
CCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHH
AEVEAAIARARAVEEAINGIVTETFELARSDASGVLSGPFAGVPSFIKDLIDWRGAPTLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
GSRGLPKQLATADNPFAAKWRGAGIVSLGKSATPEAGLISSTEPLSNGPTRNPWDLSRIP
CCCCCCHHHHCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGSSGGAAALVAARVVAFAHASDGGGSIRIPASTCGVFGMKPSRDRLPYSEPGAIPPPLQ
CCCCCCHHHHHHHHHHHHHCCCCCCCEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCE
ISVNHAVTLSVRDSIALFRAAEALDGTYPALGEIQPLTRRLRIGFAPEPIGGTELHPDTR
EEECCEEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
AALEDVAQLCRDLGHTVIDYTIPMDGPKFTDAFITYWAAGAADFARQVSEASGKPIGPDI
HHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VEPWTLGLANLAASRLTDLPGIVGYLLGFEEEYHSFFNDLDILLTPVTGSPAVPVGEQAP
CCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC
DGDFDAVMDSVLKFVAYTSPMNVAGAASMSVPLAWSPAGLPIGAMFSGRRGDDALMFELA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCEEHEECCCCCCCCEEEHHH
LELEAARPWADRKPPLSAL
HHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRLTRRAALAGGAATVALAACNPRASDTEPAADSAVAPAGFRDGVAIAAAIEAGETTAL
CCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHH
AEVEAAIARARAVEEAINGIVTETFELARSDASGVLSGPFAGVPSFIKDLIDWRGAPTLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
GSRGLPKQLATADNPFAAKWRGAGIVSLGKSATPEAGLISSTEPLSNGPTRNPWDLSRIP
CCCCCCHHHHCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGSSGGAAALVAARVVAFAHASDGGGSIRIPASTCGVFGMKPSRDRLPYSEPGAIPPPLQ
CCCCCCHHHHHHHHHHHHHCCCCCCCEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCE
ISVNHAVTLSVRDSIALFRAAEALDGTYPALGEIQPLTRRLRIGFAPEPIGGTELHPDTR
EEECCEEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
AALEDVAQLCRDLGHTVIDYTIPMDGPKFTDAFITYWAAGAADFARQVSEASGKPIGPDI
HHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VEPWTLGLANLAASRLTDLPGIVGYLLGFEEEYHSFFNDLDILLTPVTGSPAVPVGEQAP
CCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC
DGDFDAVMDSVLKFVAYTSPMNVAGAASMSVPLAWSPAGLPIGAMFSGRRGDDALMFELA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCEEHEECCCCCCCCEEEHHH
LELEAARPWADRKPPLSAL
HHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]