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The map label for this gene is zraR [H]

Identifier: 114331607

GI number: 114331607

Start: 1704929

End: 1706029

Strand: Direct

Name: zraR [H]

Synonym: Neut_1621

Alternate gene names: 114331607

Gene position: 1704929-1706029 (Clockwise)

Preceding gene: 114331606

Following gene: 114331610

Centisome position: 64.07

GC content: 48.59

Gene sequence:

>1101_bases
ATGAGCAAGTATCAGAGACAAGCTACTCACGACATTATTACCTTCCTGATTGAACAAGGAATCGAAATAAAAGACCATGA
TGATTATCTTTCTGGTCATCCTGGCGTAGTTTTCAGCAAGGAAATCACATCGGAAACTTGTGAACAATTACGTGAGCTTA
GTCATAGCGGGCAGATACCGACTCTTTTCTGTTGCGATTGTGCCATTTCGGGAAATACTATCTGGCAGCTTCTGGAAGCA
GGTGCCTGCGATGTCTTGACGTGTACAGAGTACAGGGTAATCATCCATGAAATCATTACCCGCCTGCAACGCTGGGAAAT
AATAGATTGCATGGTAAATTCACCTGCCGTACAGAATACGCTAGTAGGAGAAAGTTCGGCCCTGAAAGCAATTTTGCGCC
AGGTTGTTGAAGTAGCTCATTTTACCGATTCTTCAGTGCTGATCCTGGGTGAAAGCGGTACCGGCAAGGAATTGCTGGCA
AATCTCATTCACACCCTGGACGCTCGCCCCGACAAAGGTGATCTGGTAATACTGGATTGCAGCACTATCGTGCCGGAATT
ATCCGGTAGCGAATTTTTCGGGCATGAACGGGGCGCGTTCACAGGTGCGGTATCCTCACGGGATGGCGTATTCGCACTCG
CAAACGGTGGCACATTGTTCCTTGATGAAATAGGCGAGTTGACTCTCACTCTACAAACTCAGCTGCTGCGCGTTATTCAG
GAACATACTTTCAAACGTGTCGGTGGTAATGCCTGGCAACGCACCTCATTTCGCCTGGTTTGCGCGACCAATCGTGATCT
CCGGGCTCAAGTCCAAAAAGGTGAATTTCGGACAGATCTCTATTATCGTATCGCCAGCTATATCTGCCATTTACCCCCCT
TGCGGGAACGCACTGAAGATATCCTCCCGCTGGCCAGGTACTTTCTGAAGACAGATCATCCTGCTCAGGATCCACCTGAA
CTAGATACACCGGTTCAGGAATATTTGTTGCGCCGTGAATATCCTGGCAATGTACGGGATCTCAGGGCAAGTAGTTGCAC
GCATGCTATGCCGCTATACAGGAAAAGGCGCTATTACAGTGGGCTGCATTCCGCCAGATGA

Upstream 100 bases:

>100_bases
ACACGCCCTTTTCAATTTTCACTTCATTAAAACACTATTTTTTCGTTTGAAAATACCAGTGATGGAGGTTGAAATAGCTA
TGAAAGTCTGGGTTCATTGG

Downstream 100 bases:

>100_bases
TCGACCGACAAAAGCAGAAGGCTGGAAAGAATGGTGCGACTCAGGCTTTGAACGGGCAATCCGAGTAGCGCTAAGCCGGG
GTATCGGCCTGAAAACTATC

Product: sigma-54 factor interaction domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSKYQRQATHDIITFLIEQGIEIKDHDDYLSGHPGVVFSKEITSETCEQLRELSHSGQIPTLFCCDCAISGNTIWQLLEA
GACDVLTCTEYRVIIHEIITRLQRWEIIDCMVNSPAVQNTLVGESSALKAILRQVVEVAHFTDSSVLILGESGTGKELLA
NLIHTLDARPDKGDLVILDCSTIVPELSGSEFFGHERGAFTGAVSSRDGVFALANGGTLFLDEIGELTLTLQTQLLRVIQ
EHTFKRVGGNAWQRTSFRLVCATNRDLRAQVQKGEFRTDLYYRIASYICHLPPLRERTEDILPLARYFLKTDHPAQDPPE
LDTPVQEYLLRREYPGNVRDLRASSCTHAMPLYRKRRYYSGLHSAR

Sequences:

>Translated_366_residues
MSKYQRQATHDIITFLIEQGIEIKDHDDYLSGHPGVVFSKEITSETCEQLRELSHSGQIPTLFCCDCAISGNTIWQLLEA
GACDVLTCTEYRVIIHEIITRLQRWEIIDCMVNSPAVQNTLVGESSALKAILRQVVEVAHFTDSSVLILGESGTGKELLA
NLIHTLDARPDKGDLVILDCSTIVPELSGSEFFGHERGAFTGAVSSRDGVFALANGGTLFLDEIGELTLTLQTQLLRVIQ
EHTFKRVGGNAWQRTSFRLVCATNRDLRAQVQKGEFRTDLYYRIASYICHLPPLRERTEDILPLARYFLKTDHPAQDPPE
LDTPVQEYLLRREYPGNVRDLRASSCTHAMPLYRKRRYYSGLHSAR
>Mature_365_residues
SKYQRQATHDIITFLIEQGIEIKDHDDYLSGHPGVVFSKEITSETCEQLRELSHSGQIPTLFCCDCAISGNTIWQLLEAG
ACDVLTCTEYRVIIHEIITRLQRWEIIDCMVNSPAVQNTLVGESSALKAILRQVVEVAHFTDSSVLILGESGTGKELLAN
LIHTLDARPDKGDLVILDCSTIVPELSGSEFFGHERGAFTGAVSSRDGVFALANGGTLFLDEIGELTLTLQTQLLRVIQE
HTFKRVGGNAWQRTSFRLVCATNRDLRAQVQKGEFRTDLYYRIASYICHLPPLRERTEDILPLARYFLKTDHPAQDPPEL
DTPVQEYLLRREYPGNVRDLRASSCTHAMPLYRKRRYYSGLHSAR

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789087, Length=310, Percent_Identity=40, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1788550, Length=239, Percent_Identity=43.0962343096234, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI87082117, Length=223, Percent_Identity=46.1883408071749, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1790437, Length=302, Percent_Identity=39.0728476821192, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87082152, Length=240, Percent_Identity=42.0833333333333, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI1790299, Length=235, Percent_Identity=43.4042553191489, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87081872, Length=228, Percent_Identity=43.859649122807, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1788905, Length=226, Percent_Identity=43.3628318584071, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1786524, Length=240, Percent_Identity=43.3333333333333, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789233, Length=224, Percent_Identity=41.0714285714286, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787583, Length=226, Percent_Identity=37.6106194690265, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789828, Length=251, Percent_Identity=36.2549800796813, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87081858, Length=193, Percent_Identity=30.0518134715026, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 41239; Mature: 41108

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYQRQATHDIITFLIEQGIEIKDHDDYLSGHPGVVFSKEITSETCEQLRELSHSGQIP
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCC
TLFCCDCAISGNTIWQLLEAGACDVLTCTEYRVIIHEIITRLQRWEIIDCMVNSPAVQNT
EEEEEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LVGESSALKAILRQVVEVAHFTDSSVLILGESGTGKELLANLIHTLDARPDKGDLVILDC
HCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEEH
STIVPELSGSEFFGHERGAFTGAVSSRDGVFALANGGTLFLDEIGELTLTLQTQLLRVIQ
HHHCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCEEEEECCCCEEHHHHHHHHHHHH
EHTFKRVGGNAWQRTSFRLVCATNRDLRAQVQKGEFRTDLYYRIASYICHLPPLRERTED
HHHHHHHCCCCEECCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHH
ILPLARYFLKTDHPAQDPPELDTPVQEYLLRREYPGNVRDLRASSCTHAMPLYRKRRYYS
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHH
GLHSAR
HHHCCC
>Mature Secondary Structure 
SKYQRQATHDIITFLIEQGIEIKDHDDYLSGHPGVVFSKEITSETCEQLRELSHSGQIP
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCC
TLFCCDCAISGNTIWQLLEAGACDVLTCTEYRVIIHEIITRLQRWEIIDCMVNSPAVQNT
EEEEEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LVGESSALKAILRQVVEVAHFTDSSVLILGESGTGKELLANLIHTLDARPDKGDLVILDC
HCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEEH
STIVPELSGSEFFGHERGAFTGAVSSRDGVFALANGGTLFLDEIGELTLTLQTQLLRVIQ
HHHCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCEEEEECCCCEEHHHHHHHHHHHH
EHTFKRVGGNAWQRTSFRLVCATNRDLRAQVQKGEFRTDLYYRIASYICHLPPLRERTED
HHHHHHHCCCCEECCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHH
ILPLARYFLKTDHPAQDPPELDTPVQEYLLRREYPGNVRDLRASSCTHAMPLYRKRRYYS
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHH
GLHSAR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]