Click here to switch to the map view.

The map label for this gene is insK [C]

Identifier: 114331610

GI number: 114331610

Start: 1708911

End: 1709759

Strand: Direct

Name: insK [C]

Synonym: Neut_1624

Alternate gene names: 114331610

Gene position: 1708911-1709759 (Clockwise)

Preceding gene: 114331607

Following gene: 114331613

Centisome position: 64.22

GC content: 57.6

Gene sequence:

>849_bases
TTGCAGGTCGCCCCATCAGGGTATCGGCGATATTTCGCGCAACAGCGTAATCCGGCTTTGCGCAGTGCCCGCGTCCTGCG
TGATGATAAACTGCTGCCGCAAATACAGCGGGTCTGGCAGACCAACATGCAGGTCTATGGTGCCGACAAGGTCTGGCGTC
AGCTTAAGCGTGAAGATGTCCAGGTGGCACGCTGTACGGTCGAACGGCTCATGAAACGGTTAGGGTTGAAAGGTGCCAGG
CGTGGCAAGGTTGTGCGCACCACAGTTCCGGACAAGGCGCTGACGTGTCCACTGGATCGGGTTAACCGGCAATTCAAGGC
AGATCGTCCGAACCAGTTGTGGGTGTCAGACTTCACCTATGTCTCGACCTGGCAAGGCTGGCTGTATGTGGCTTTCGTCA
TCGATGTATTTGCCCGGCGCATTGTGGGCTGGCAGGTGAGCAGCTCCATGCGCACGGACTTTGTGCTGGATGCCCTGGAA
CAAGCGCTGTATGCCCGGCAACCGGGGCGGATGGATGCCTTGGTACACCATAGCGACAGAGGCTCGCAATATGTCTCCAT
TCGCTATACCGAGCGACTCGCCGAAGCCGGAATAGAACCCTCGGTCGGCAGCAAGGGCGACAGCTACGACAACGCGCTGG
CAGAAACCATCAATGGGCTGTACAAAACAGAATTGATTCACAAGCGCGCCCCCTGGAAAACCAGGGAGGCCGTGGAGCTG
GCAACGCTGGAATGGGTAGCCTGGTTCAACAACCAGCGGCTGCTGGAACCAATCGGTTACATCCCTCCCGCAGAAGCTGA
GGTAAACTACTATAGGCAATTCGCCAGGGAAGCCATTCCGGTGGCTTGA

Upstream 100 bases:

>100_bases
CTTTTTTCGCTCAGGTGGAGCTCGACCGCAAACTCAAATCCAGGGATCGTTCATCGACCAGTACCGCGACGCCCATGGGG
TCGAGCCGATCTGCAAGGTT

Downstream 100 bases:

>100_bases
CTTTAACCAAACAGCCTCCTCAAAACCCGGGACGATTCAGTCCGGAGATTTGTTTCGATTGCTTTATGTTGAGGAGTCAG
TACCCAGCAGAAGGAATAAT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MQVAPSGYRRYFAQQRNPALRSARVLRDDKLLPQIQRVWQTNMQVYGADKVWRQLKREDVQVARCTVERLMKRLGLKGAR
RGKVVRTTVPDKALTCPLDRVNRQFKADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWQVSSSMRTDFVLDALE
QALYARQPGRMDALVHHSDRGSQYVSIRYTERLAEAGIEPSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVEL
ATLEWVAWFNNQRLLEPIGYIPPAEAEVNYYRQFAREAIPVA

Sequences:

>Translated_282_residues
MQVAPSGYRRYFAQQRNPALRSARVLRDDKLLPQIQRVWQTNMQVYGADKVWRQLKREDVQVARCTVERLMKRLGLKGAR
RGKVVRTTVPDKALTCPLDRVNRQFKADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWQVSSSMRTDFVLDALE
QALYARQPGRMDALVHHSDRGSQYVSIRYTERLAEAGIEPSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVEL
ATLEWVAWFNNQRLLEPIGYIPPAEAEVNYYRQFAREAIPVA
>Mature_282_residues
MQVAPSGYRRYFAQQRNPALRSARVLRDDKLLPQIQRVWQTNMQVYGADKVWRQLKREDVQVARCTVERLMKRLGLKGAR
RGKVVRTTVPDKALTCPLDRVNRQFKADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWQVSSSMRTDFVLDALE
QALYARQPGRMDALVHHSDRGSQYVSIRYTERLAEAGIEPSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVEL
ATLEWVAWFNNQRLLEPIGYIPPAEAEVNYYRQFAREAIPVA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=240, Percent_Identity=54.5833333333333, Blast_Score=250, Evalue=1e-66,
Organism=Escherichia coli, GI1789981, Length=232, Percent_Identity=31.4655172413793, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788405, Length=225, Percent_Identity=31.1111111111111, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787263, Length=225, Percent_Identity=31.1111111111111, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786753, Length=225, Percent_Identity=31.1111111111111, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786570, Length=225, Percent_Identity=31.1111111111111, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786490, Length=225, Percent_Identity=31.1111111111111, Blast_Score=111, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32665; Mature: 32665

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVAPSGYRRYFAQQRNPALRSARVLRDDKLLPQIQRVWQTNMQVYGADKVWRQLKREDV
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHH
QVARCTVERLMKRLGLKGARRGKVVRTTVPDKALTCPLDRVNRQFKADRPNQLWVSDFTY
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHCCCHHHHHHHHCCCCCCEEEECCCHH
VSTWQGWLYVAFVIDVFARRIVGWQVSSSMRTDFVLDALEQALYARQPGRMDALVHHSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHEEECCC
GSQYVSIRYTERLAEAGIEPSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVEL
CCEEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ATLEWVAWFNNQRLLEPIGYIPPAEAEVNYYRQFAREAIPVA
HHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQVAPSGYRRYFAQQRNPALRSARVLRDDKLLPQIQRVWQTNMQVYGADKVWRQLKREDV
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHH
QVARCTVERLMKRLGLKGARRGKVVRTTVPDKALTCPLDRVNRQFKADRPNQLWVSDFTY
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHCCCHHHHHHHHCCCCCCEEEECCCHH
VSTWQGWLYVAFVIDVFARRIVGWQVSSSMRTDFVLDALEQALYARQPGRMDALVHHSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHEEECCC
GSQYVSIRYTERLAEAGIEPSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVEL
CCEEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ATLEWVAWFNNQRLLEPIGYIPPAEAEVNYYRQFAREAIPVA
HHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]