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The map label for this gene is czcC [H]

Identifier: 114331548

GI number: 114331548

Start: 1633780

End: 1635084

Strand: Direct

Name: czcC [H]

Synonym: Neut_1561

Alternate gene names: 114331548

Gene position: 1633780-1635084 (Clockwise)

Preceding gene: 114331547

Following gene: 114331549

Centisome position: 61.4

GC content: 54.79

Gene sequence:

>1305_bases
ATGTGGAAATCGACTGTCATGCGCTGTTCAGCGCTATTTATCCTTGCTTTGTGGGCCGTACTCCCAGGTAACAGCCAAGC
CTACGATATTACCGTCAGTCTGAAAGAAGCCGAGCAGTTGGCGCTGACTCGTAACCGCGATCTCCGCTTTGCCCGACGAA
ATATTGAAGCTGCGGCAGCGGAAACACTCAATGCAGCTGCTTTTCCCAACCCCACACTTGCGGTTAATGCCAGTCATTTA
AACCTTAAATCTGACCCAACTACTGCATTCAGCTCCAGAACGCCAACCGAAAGCGAAATTCGTATCGATCAGACTTTTGA
ACGAGGTGGTAAGAGAGCGCTCCGTATGGCACAAGCAGACAGTAAACTCACCGCTACTCGGTTCGATTTTGACGATACGC
TGCGGCAAACTCGGTTCAATGCACGCAGCGCTTGGTTTGAACTTAAACTGGCTGAGCATCACGTTGAACTGAGCGGCATT
ATTGCCAGCCAGTCCGAGCATATATTGGAATTGGCTCGACGCCGCTATCAAGCAGGCGATCTATCCGGTGCTGATCTGGG
GCGCTTCGAAACCGATGCTGCCCGAGCCCGAGCGGGTGTGCGCACAGCAGAAAGCACGCTTACACGCGCCCGCACTGCAT
TGGGTATTTTGTTAGCTGACGAAAACCATGCGTTACAGCTTGTCACTCGGGGCGACTGGCCGGCAGAAAGAGCCAGATTG
CCTGACGCAGCCACTATCACCACCGCTATTTCCCAGCGTCCGGATACACTTGCCGCTGCCGCACGAATGGAAGCCGCTCG
ACATAACGTTGGGCTGGCACAGGCAAAGCGCACTCGCGACGTTACTGTCAGCCTCCAATATGAACGTCAACCAGCCGATG
TGACACAACCACGCAATTCTCTTGGTCTTGAGGTTTCCATTCCATTGTTTCTTGGCAACTACTTTGAGGGCGATATCCGC
CACGCTCATGCCGAGCTCGCTCTGGCCGAAGATCAGCTGGAAGCAATTCGCGCCCGCATCCAGGCTGAAATTAACCAGCT
TGTCGATGAATTACAACATGCCAGCGACCGCTGGCATGCCTTGCAGGAACAAGCACTACCGGCTGCCCGCCGTACTGCCA
GCGCAGCAGAGCTTGCTTTCAGCAAGGGAGCGATCAGCGCGCTGGAGTTTCTGGATGCGCAGCGCATTCTGCGGACTGCC
GAGCTGGATACACTGCAAGCCCGCAGTGATCTGGCACAAGCAAGCGCCGCTCTGGATGCAGCACTGGAAACTACCATCTC
CAAGGAACAGGAACCCGCTTCATGA

Upstream 100 bases:

>100_bases
ACACCGTACCACTGACACCCCATACCGCTTCATTGTTCGTTTCTATTTCCTGCCGAAATTCGTCAGGCAAACGCAAGTTG
AAGCAGTCTATATTTACCTC

Downstream 100 bases:

>100_bases
TGAAACTCCGATTATGCAAGATCAAAGTGGTTGCCGCTACCCTGGCAATAGTGATTACAGGTGTTGCTGGTTATTTGTAT
TTCAGCCAGGCTGTTATCCA

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MWKSTVMRCSALFILALWAVLPGNSQAYDITVSLKEAEQLALTRNRDLRFARRNIEAAAAETLNAAAFPNPTLAVNASHL
NLKSDPTTAFSSRTPTESEIRIDQTFERGGKRALRMAQADSKLTATRFDFDDTLRQTRFNARSAWFELKLAEHHVELSGI
IASQSEHILELARRRYQAGDLSGADLGRFETDAARARAGVRTAESTLTRARTALGILLADENHALQLVTRGDWPAERARL
PDAATITTAISQRPDTLAAAARMEAARHNVGLAQAKRTRDVTVSLQYERQPADVTQPRNSLGLEVSIPLFLGNYFEGDIR
HAHAELALAEDQLEAIRARIQAEINQLVDELQHASDRWHALQEQALPAARRTASAAELAFSKGAISALEFLDAQRILRTA
ELDTLQARSDLAQASAALDAALETTISKEQEPAS

Sequences:

>Translated_434_residues
MWKSTVMRCSALFILALWAVLPGNSQAYDITVSLKEAEQLALTRNRDLRFARRNIEAAAAETLNAAAFPNPTLAVNASHL
NLKSDPTTAFSSRTPTESEIRIDQTFERGGKRALRMAQADSKLTATRFDFDDTLRQTRFNARSAWFELKLAEHHVELSGI
IASQSEHILELARRRYQAGDLSGADLGRFETDAARARAGVRTAESTLTRARTALGILLADENHALQLVTRGDWPAERARL
PDAATITTAISQRPDTLAAAARMEAARHNVGLAQAKRTRDVTVSLQYERQPADVTQPRNSLGLEVSIPLFLGNYFEGDIR
HAHAELALAEDQLEAIRARIQAEINQLVDELQHASDRWHALQEQALPAARRTASAAELAFSKGAISALEFLDAQRILRTA
ELDTLQARSDLAQASAALDAALETTISKEQEPAS
>Mature_434_residues
MWKSTVMRCSALFILALWAVLPGNSQAYDITVSLKEAEQLALTRNRDLRFARRNIEAAAAETLNAAAFPNPTLAVNASHL
NLKSDPTTAFSSRTPTESEIRIDQTFERGGKRALRMAQADSKLTATRFDFDDTLRQTRFNARSAWFELKLAEHHVELSGI
IASQSEHILELARRRYQAGDLSGADLGRFETDAARARAGVRTAESTLTRARTALGILLADENHALQLVTRGDWPAERARL
PDAATITTAISQRPDTLAAAARMEAARHNVGLAQAKRTRDVTVSLQYERQPADVTQPRNSLGLEVSIPLFLGNYFEGDIR
HAHAELALAEDQLEAIRARIQAEINQLVDELQHASDRWHALQEQALPAARRTASAAELAFSKGAISALEFLDAQRILRTA
ELDTLQARSDLAQASAALDAALETTISKEQEPAS

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47701; Mature: 47701

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKSTVMRCSALFILALWAVLPGNSQAYDITVSLKEAEQLALTRNRDLRFARRNIEAAAA
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
ETLNAAAFPNPTLAVNASHLNLKSDPTTAFSSRTPTESEIRIDQTFERGGKRALRMAQAD
HHHHHCCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCC
SKLTATRFDFDDTLRQTRFNARSAWFELKLAEHHVELSGIIASQSEHILELARRRYQAGD
CCCEEEECCHHHHHHHHHCCCHHHHEEEEEHHHHHHHHHEECCCHHHHHHHHHHHHCCCC
LSGADLGRFETDAARARAGVRTAESTLTRARTALGILLADENHALQLVTRGDWPAERARL
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCHHHHCC
PDAATITTAISQRPDTLAAAARMEAARHNVGLAQAKRTRDVTVSLQYERQPADVTQPRNS
CCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCCCHH
LGLEVSIPLFLGNYFEGDIRHAHAELALAEDQLEAIRARIQAEINQLVDELQHASDRWHA
CCCEEEEHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQEQALPAARRTASAAELAFSKGAISALEFLDAQRILRTAELDTLQARSDLAQASAALDA
HHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALETTISKEQEPAS
HHHHHHHCCCCCCC
>Mature Secondary Structure
MWKSTVMRCSALFILALWAVLPGNSQAYDITVSLKEAEQLALTRNRDLRFARRNIEAAAA
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
ETLNAAAFPNPTLAVNASHLNLKSDPTTAFSSRTPTESEIRIDQTFERGGKRALRMAQAD
HHHHHCCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCC
SKLTATRFDFDDTLRQTRFNARSAWFELKLAEHHVELSGIIASQSEHILELARRRYQAGD
CCCEEEECCHHHHHHHHHCCCHHHHEEEEEHHHHHHHHHEECCCHHHHHHHHHHHHCCCC
LSGADLGRFETDAARARAGVRTAESTLTRARTALGILLADENHALQLVTRGDWPAERARL
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCHHHHCC
PDAATITTAISQRPDTLAAAARMEAARHNVGLAQAKRTRDVTVSLQYERQPADVTQPRNS
CCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCCCHH
LGLEVSIPLFLGNYFEGDIRHAHAELALAEDQLEAIRARIQAEINQLVDELQHASDRWHA
CCCEEEEHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQEQALPAARRTASAAELAFSKGAISALEFLDAQRILRTAELDTLQARSDLAQASAALDA
HHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALETTISKEQEPAS
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]