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The map label for this gene is cusB [H]

Identifier: 114331549

GI number: 114331549

Start: 1635081

End: 1636250

Strand: Direct

Name: cusB [H]

Synonym: Neut_1562

Alternate gene names: 114331549

Gene position: 1635081-1636250 (Clockwise)

Preceding gene: 114331548

Following gene: 114331550

Centisome position: 61.44

GC content: 52.91

Gene sequence:

>1170_bases
ATGATGAAACTCCGATTATGCAAGATCAAAGTGGTTGCCGCTACCCTGGCAATAGTGATTACAGGTGTTGCTGGTTATTT
GTATTTCAGCCAGGCTGTTATCCAGCCTCCGACAGAAAATACTGGATCAAACCGCACCCGGAATCAACTGCTATTCCCGC
CGGGAGCCCCTCAGCTTGCCTACATTAAAACCAGCCCTGCCGTCTCGGCAATGCTGCCGGCCAGTGAGCCACTGGCTGCA
AAGCTGGCACTGGCAGAAAACCTTACTGCTCGTATCAGCCCGGCTGTGGCAGGCCGTATCTTGCAGCTGCATGTCGAGAT
TGGCGATCAGGTTAAGGCTGGTACGCCACTGGTAACATTAGATTCGCCTGATTTTGGGGCAGCCATCGCCGATCTTCATA
AGGCAGAAGCAGATGCCACCTACAAATCACTCACTTATAAACGAGCGCGCGAGCTTTGGGCCGGTGAAGCCATCGCCCGG
CGTGATGTGGAAAGCGCCCGTGCGGACTGGCAAATTGCAGCCGCAGAAGCTAAGCGTGCACAATTGCGGGTAAGAAATCT
GGTACCGGATGGCAAGATGCAGGATGAAAAATTGGTGTTATATGCACCAATTGACGGTACGGTGGCTTATCGCCAGGCTA
ACCCCGGCCTGGAAGTTCGCCCGGATATGGCCGCACCCTTATTTGTCATTTCCAATCTATCGCATTTATGGGTGTTGGTG
GATGTTCCTGAACGATTAATCAGCCGGGTACAAAGCGGCAATCCACTGCTGCTCAACTTCGATGCATTTCCGGAAAAATC
CTTCCTTGCCACCATTACCCGTATTGCCCCCGTACTTGATCCGAATGTTCGCCGAGTACAGGTGCGCGCTGAAATAGACA
ATCCGGACGGCACGCTACGGCCAGAAATGTTTGCCCGTGCCCAGTTGATCGATCCACGAGCGGATAGCGTAGTTCAATTA
CCGGCAGAATCAGTCATTACCGGTGGGGTTCATCCCACCGTATTCGTTGAGACTAATGCGGGTGAATTTATTCAGCGCCG
TATCCGCATTGCCTTCCAGGATGCTGAATCTGTCTGGCTCGAACCGGAAAATGGAGGGGTAGCAGTCGGAGAAGAGGTCG
TGATCGACGGCACCATGCTGCTGACTTCAGAACTTGCTGCTGGAAACTAA

Upstream 100 bases:

>100_bases
AGCTGGATACACTGCAAGCCCGCAGTGATCTGGCACAAGCAAGCGCCGCTCTGGATGCAGCACTGGAAACTACCATCTCC
AAGGAACAGGAACCCGCTTC

Downstream 100 bases:

>100_bases
AATGCTCAGTCGTCTTATCTCATTTTCGATCAAACAGCGGCTTTTTATTCTCGTGATGACGGGAGCACTGCTGGTGGCCG
GCATACATGCTTTTATCGAA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MMKLRLCKIKVVAATLAIVITGVAGYLYFSQAVIQPPTENTGSNRTRNQLLFPPGAPQLAYIKTSPAVSAMLPASEPLAA
KLALAENLTARISPAVAGRILQLHVEIGDQVKAGTPLVTLDSPDFGAAIADLHKAEADATYKSLTYKRARELWAGEAIAR
RDVESARADWQIAAAEAKRAQLRVRNLVPDGKMQDEKLVLYAPIDGTVAYRQANPGLEVRPDMAAPLFVISNLSHLWVLV
DVPERLISRVQSGNPLLLNFDAFPEKSFLATITRIAPVLDPNVRRVQVRAEIDNPDGTLRPEMFARAQLIDPRADSVVQL
PAESVITGGVHPTVFVETNAGEFIQRRIRIAFQDAESVWLEPENGGVAVGEEVVIDGTMLLTSELAAGN

Sequences:

>Translated_389_residues
MMKLRLCKIKVVAATLAIVITGVAGYLYFSQAVIQPPTENTGSNRTRNQLLFPPGAPQLAYIKTSPAVSAMLPASEPLAA
KLALAENLTARISPAVAGRILQLHVEIGDQVKAGTPLVTLDSPDFGAAIADLHKAEADATYKSLTYKRARELWAGEAIAR
RDVESARADWQIAAAEAKRAQLRVRNLVPDGKMQDEKLVLYAPIDGTVAYRQANPGLEVRPDMAAPLFVISNLSHLWVLV
DVPERLISRVQSGNPLLLNFDAFPEKSFLATITRIAPVLDPNVRRVQVRAEIDNPDGTLRPEMFARAQLIDPRADSVVQL
PAESVITGGVHPTVFVETNAGEFIQRRIRIAFQDAESVWLEPENGGVAVGEEVVIDGTMLLTSELAAGN
>Mature_389_residues
MMKLRLCKIKVVAATLAIVITGVAGYLYFSQAVIQPPTENTGSNRTRNQLLFPPGAPQLAYIKTSPAVSAMLPASEPLAA
KLALAENLTARISPAVAGRILQLHVEIGDQVKAGTPLVTLDSPDFGAAIADLHKAEADATYKSLTYKRARELWAGEAIAR
RDVESARADWQIAAAEAKRAQLRVRNLVPDGKMQDEKLVLYAPIDGTVAYRQANPGLEVRPDMAAPLFVISNLSHLWVLV
DVPERLISRVQSGNPLLLNFDAFPEKSFLATITRIAPVLDPNVRRVQVRAEIDNPDGTLRPEMFARAQLIDPRADSVVQL
PAESVITGGVHPTVFVETNAGEFIQRRIRIAFQDAESVWLEPENGGVAVGEEVVIDGTMLLTSELAAGN

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=332, Percent_Identity=26.2048192771084, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI87082036, Length=340, Percent_Identity=24.4117647058824, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789929, Length=304, Percent_Identity=23.0263157894737, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787013, Length=283, Percent_Identity=24.3816254416961, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786668, Length=337, Percent_Identity=25.2225519287834, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42142; Mature: 42142

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLRLCKIKVVAATLAIVITGVAGYLYFSQAVIQPPTENTGSNRTRNQLLFPPGAPQLA
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEE
YIKTSPAVSAMLPASEPLAAKLALAENLTARISPAVAGRILQLHVEIGDQVKAGTPLVTL
EEECCCCCEEECCCCCCHHHHHHHHHCCHHHCCHHHHCEEEEEEEEECCCCCCCCCEEEE
DSPDFGAAIADLHKAEADATYKSLTYKRARELWAGEAIARRDVESARADWQIAAAEAKRA
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEHHHHHHH
QLRVRNLVPDGKMQDEKLVLYAPIDGTVAYRQANPGLEVRPDMAAPLFVISNLSHLWVLV
HHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEECCCCCCHHHHHCCCCCEEEEE
DVPERLISRVQSGNPLLLNFDAFPEKSFLATITRIAPVLDPNVRRVQVRAEIDNPDGTLR
ECHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCC
PEMFARAQLIDPRADSVVQLPAESVITGGVHPTVFVETNAGEFIQRRIRIAFQDAESVWL
HHHHHHHHCCCCCCCCEEECCHHHHEECCCCCEEEEECCCHHHHHHHHHEEEECCCEEEE
EPENGGVAVGEEVVIDGTMLLTSELAAGN
ECCCCCEEECCEEEECCEEEEEEHHCCCC
>Mature Secondary Structure
MMKLRLCKIKVVAATLAIVITGVAGYLYFSQAVIQPPTENTGSNRTRNQLLFPPGAPQLA
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEE
YIKTSPAVSAMLPASEPLAAKLALAENLTARISPAVAGRILQLHVEIGDQVKAGTPLVTL
EEECCCCCEEECCCCCCHHHHHHHHHCCHHHCCHHHHCEEEEEEEEECCCCCCCCCEEEE
DSPDFGAAIADLHKAEADATYKSLTYKRARELWAGEAIARRDVESARADWQIAAAEAKRA
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEHHHHHHH
QLRVRNLVPDGKMQDEKLVLYAPIDGTVAYRQANPGLEVRPDMAAPLFVISNLSHLWVLV
HHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEECCCCCCHHHHHCCCCCEEEEE
DVPERLISRVQSGNPLLLNFDAFPEKSFLATITRIAPVLDPNVRRVQVRAEIDNPDGTLR
ECHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCC
PEMFARAQLIDPRADSVVQLPAESVITGGVHPTVFVETNAGEFIQRRIRIAFQDAESVWL
HHHHHHHHCCCCCCCCEEECCHHHHEECCCCCEEEEECCCHHHHHHHHHEEEECCCEEEE
EPENGGVAVGEEVVIDGTMLLTSELAAGN
ECCCCCEEECCEEEECCEEEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]