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The map label for this gene is erpA

Identifier: 114331529

GI number: 114331529

Start: 1610669

End: 1611034

Strand: Direct

Name: erpA

Synonym: Neut_1542

Alternate gene names: 114331529

Gene position: 1610669-1611034 (Clockwise)

Preceding gene: 114331528

Following gene: 114331532

Centisome position: 60.53

GC content: 44.26

Gene sequence:

>366_bases
ATGAACACGATAACCCATGAAGAAGCAAATACAGTTCAACCCCCGTTATTTTTTACCGATAGCGCTGCCAGCAAGGTAAA
AGAACTGATTGAAGAAGAAGCAAACCAGGCACTCAAACTGAGAGTTTTCGTCAGCGGAGGGGGATGCTCCGGATTTCAAT
ACGGTTTTACATTTGATGAAATTATCAATGAAGATGACTTTGTAATAGAAAAGCAAGGAGTTAGGCTCCTGGTGGATTCA
ATGAGCGTTCAATATCTGCTGGGAGCGGAAATCGATTATCAGGAAAATGCCCAGGGTGCACAATTTGTCATCAAGAATCC
AGCTGCAGCCAGTACCTGTGGATGTGGCTCCTCATTCTCGGTCTGA

Upstream 100 bases:

>100_bases
TTGCTGTCTGGCAAAGAGGGTACAGATAAATTTCAGAACCACCAAAGCAGCAGTAATCGCTTAATATCAGAATAATCAGT
TACATAAATAAGTGAATAAA

Downstream 100 bases:

>100_bases
AAGAATTTTCAGGCAGGATAAATCGCGCCCAGTACCCGCCTACCGGTTGCGCCGGTCACGGCGGGAAGATTTCCAGGAGT
GCGTTCAATTGATTGTCGCG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MNTITHEEANTVQPPLFFTDSAASKVKELIEEEANQALKLRVFVSGGGCSGFQYGFTFDEIINEDDFVIEKQGVRLLVDS
MSVQYLLGAEIDYQENAQGAQFVIKNPAAASTCGCGSSFSV

Sequences:

>Translated_121_residues
MNTITHEEANTVQPPLFFTDSAASKVKELIEEEANQALKLRVFVSGGGCSGFQYGFTFDEIINEDDFVIEKQGVRLLVDS
MSVQYLLGAEIDYQENAQGAQFVIKNPAAASTCGCGSSFSV
>Mature_121_residues
MNTITHEEANTVQPPLFFTDSAASKVKELIEEEANQALKLRVFVSGGGCSGFQYGFTFDEIINEDDFVIEKQGVRLLVDS
MSVQYLLGAEIDYQENAQGAQFVIKNPAAASTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters (Potential)

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=122, Percent_Identity=40.1639344262295, Blast_Score=89, Evalue=9e-19,
Organism=Homo sapiens, GI52426768, Length=121, Percent_Identity=28.9256198347107, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786351, Length=113, Percent_Identity=61.9469026548673, Blast_Score=155, Evalue=9e-40,
Organism=Escherichia coli, GI1788877, Length=104, Percent_Identity=34.6153846153846, Blast_Score=69, Evalue=8e-14,
Organism=Escherichia coli, GI1787974, Length=108, Percent_Identity=31.4814814814815, Blast_Score=63, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71998452, Length=105, Percent_Identity=39.0476190476191, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25146411, Length=109, Percent_Identity=31.1926605504587, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=109, Percent_Identity=31.1926605504587, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=82, Percent_Identity=36.5853658536585, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649697, Length=119, Percent_Identity=38.655462184874, Blast_Score=82, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=32.0754716981132, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_NITEC (Q0AFU6)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747751.1
- ProteinModelPortal:   Q0AFU6
- SMR:   Q0AFU6
- STRING:   Q0AFU6
- GeneID:   4273623
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1542
- NMPDR:   fig|335283.3.peg.1824
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   CSGFEYK
- PhylomeDB:   Q0AFU6
- ProtClustDB:   PRK13623
- BioCyc:   NEUT335283:NEUT_1542-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13125; Mature: 13125

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTITHEEANTVQPPLFFTDSAASKVKELIEEEANQALKLRVFVSGGGCSGFQYGFTFDE
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCHHH
IINEDDFVIEKQGVRLLVDSMSVQYLLGAEIDYQENAQGAQFVIKNPAAASTCGCGSSFS
HCCCCCEEEECCCCEEEEECCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
V
C
>Mature Secondary Structure
MNTITHEEANTVQPPLFFTDSAASKVKELIEEEANQALKLRVFVSGGGCSGFQYGFTFDE
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCHHH
IINEDDFVIEKQGVRLLVDSMSVQYLLGAEIDYQENAQGAQFVIKNPAAASTCGCGSSFS
HCCCCCEEEECCCCEEEEECCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA