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The map label for this gene is surA [C]

Identifier: 114331519

GI number: 114331519

Start: 1602325

End: 1603119

Strand: Reverse

Name: surA [C]

Synonym: Neut_1532

Alternate gene names: 114331519

Gene position: 1603119-1602325 (Counterclockwise)

Preceding gene: 114331520

Following gene: 114331516

Centisome position: 60.24

GC content: 47.3

Gene sequence:

>795_bases
ATGCGCTTAACCAAGTTTCTCTGTGTGCCACTTGCTGTGCTGGGATTTGTATGTACTACGCCCTTAAGTGCCCAGGGCGG
TGGTACAGTCGCCAAAGTTAACGGTATAGCGATACCACAATCACGCCTTGACCTGGTGATCAAGGCAGCAACAGCGCAGG
GTCAACCCGATTCAGCTGAAATGAGAAATGCTTTGCGCGAAAATCTCATCACGGAAGAAGTACTGACACAAGAAGCAATA
AAAAAGGGGCTTGACCGTAATCCGGATGTTGTCACACAGATTGATCTGGCGCGCCAGGGAATATTGATCAGGGCGTATCA
GGCTGATTTTATGCGAAATAATCCGGTTAGCGATGATGAATTACGCAAGGAATATGAATCAGTAAAATCACAGATGGGTG
ATAAGGAATACAAAGCACGCCATATTCTTGTGGAAACCGAACAAGAAGCCAAGGATTTGGTTGCCTCTCTGAAAAAGGGT
GGCGTGTTTGAGAAACTGGCTGGTGAGCGCTCCATTGATACCGGCAGCAAGAGTAATGGTGGGGAGCTGGGCTGGAGCTC
GGCGGCAGTTTATGTTAAGCCCTTTTCCGATGCATTGACCAAACTGAAAAAAGGCGAAACAACCAGTCAGCCAGTACAAA
CGCCCTTTGGTTGGCATGTAATTCGTCTGGATGATGTGCGTACTGCTGTTCCACCTTCTTTTGACGAAGTAAAACAAAAT
ATGCAGCAGCGGGTATTACAGCGCAAGTTTGCAGCGGTGGTTGAGTCGTTGCGTAAAAATGCCAAAGTTGAATAA

Upstream 100 bases:

>100_bases
TTGTTTTCAAAAAGAACTTATCCGTGTTTTGTTAAAATGTATGCTTTTTAGATTATTCAGATAAAATTTGTCAACTACTT
TACTATTTAAAGGAAATTTT

Downstream 100 bases:

>100_bases
TCAGGTATTAACAAAAAATCTGTAATCATTAGCTTATGCTGATGCTCGGTACTCTGGGAGAGAGTGCTGTCAGTAGCTCG
TAACTGATAGTTTGTGCCGA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MRLTKFLCVPLAVLGFVCTTPLSAQGGGTVAKVNGIAIPQSRLDLVIKAATAQGQPDSAEMRNALRENLITEEVLTQEAI
KKGLDRNPDVVTQIDLARQGILIRAYQADFMRNNPVSDDELRKEYESVKSQMGDKEYKARHILVETEQEAKDLVASLKKG
GVFEKLAGERSIDTGSKSNGGELGWSSAAVYVKPFSDALTKLKKGETTSQPVQTPFGWHVIRLDDVRTAVPPSFDEVKQN
MQQRVLQRKFAAVVESLRKNAKVE

Sequences:

>Translated_264_residues
MRLTKFLCVPLAVLGFVCTTPLSAQGGGTVAKVNGIAIPQSRLDLVIKAATAQGQPDSAEMRNALRENLITEEVLTQEAI
KKGLDRNPDVVTQIDLARQGILIRAYQADFMRNNPVSDDELRKEYESVKSQMGDKEYKARHILVETEQEAKDLVASLKKG
GVFEKLAGERSIDTGSKSNGGELGWSSAAVYVKPFSDALTKLKKGETTSQPVQTPFGWHVIRLDDVRTAVPPSFDEVKQN
MQQRVLQRKFAAVVESLRKNAKVE
>Mature_264_residues
MRLTKFLCVPLAVLGFVCTTPLSAQGGGTVAKVNGIAIPQSRLDLVIKAATAQGQPDSAEMRNALRENLITEEVLTQEAI
KKGLDRNPDVVTQIDLARQGILIRAYQADFMRNNPVSDDELRKEYESVKSQMGDKEYKARHILVETEQEAKDLVASLKKG
GVFEKLAGERSIDTGSKSNGGELGWSSAAVYVKPFSDALTKLKKGETTSQPVQTPFGWHVIRLDDVRTAVPPSFDEVKQN
MQQRVLQRKFAAVVESLRKNAKVE

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=144, Percent_Identity=34.7222222222222, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786645, Length=137, Percent_Identity=32.8467153284672, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29083; Mature: 29083

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTKFLCVPLAVLGFVCTTPLSAQGGGTVAKVNGIAIPQSRLDLVIKAATAQGQPDSAE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEECCHHHHHHHEEECCCCCCCCHHH
MRNALRENLITEEVLTQEAIKKGLDRNPDVVTQIDLARQGILIRAYQADFMRNNPVSDDE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEHHHHHHCCCCCCHHH
LRKEYESVKSQMGDKEYKARHILVETEQEAKDLVASLKKGGVFEKLAGERSIDTGSKSNG
HHHHHHHHHHHHCCHHHHHHEEEEECHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
GELGWSSAAVYVKPFSDALTKLKKGETTSQPVQTPFGWHVIRLDDVRTAVPPSFDEVKQN
CCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHH
MQQRVLQRKFAAVVESLRKNAKVE
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLTKFLCVPLAVLGFVCTTPLSAQGGGTVAKVNGIAIPQSRLDLVIKAATAQGQPDSAE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEECCHHHHHHHEEECCCCCCCCHHH
MRNALRENLITEEVLTQEAIKKGLDRNPDVVTQIDLARQGILIRAYQADFMRNNPVSDDE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEHHHHHHCCCCCCHHH
LRKEYESVKSQMGDKEYKARHILVETEQEAKDLVASLKKGGVFEKLAGERSIDTGSKSNG
HHHHHHHHHHHHCCHHHHHHEEEEECHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
GELGWSSAAVYVKPFSDALTKLKKGETTSQPVQTPFGWHVIRLDDVRTAVPPSFDEVKQN
CCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHH
MQQRVLQRKFAAVVESLRKNAKVE
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]