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The map label for this gene is murB [H]

Identifier: 113477458

GI number: 113477458

Start: 6226077

End: 6227024

Strand: Reverse

Name: murB [H]

Synonym: Tery_4028

Alternate gene names: 113477458

Gene position: 6227024-6226077 (Counterclockwise)

Preceding gene: 113477459

Following gene: 113477457

Centisome position: 80.35

GC content: 40.61

Gene sequence:

>948_bases
ATGACTCTTTCTTATCACATAGCTAGTTCAGAAAAAATGCCACAAAGACAACCTATTCCCTTGTTAGGAAAAGACTGTGT
AATTAAGTCTAATGTTCCTCTGGCACCTCTAACGTCTTTCCGCGTTGGAGGGCCTGCTGAATGGTATGTTACACCAAAAA
GATTAGATCAACTACAAGCTAGTTTTCAGTTTGCTAACTATAAAGGATTACCAATAACTTTTCTAGGAGCAGGATCTAAT
ATACTAGTCAGCGATAGTGGTTTATCTGGATTAGTTATTGGCAGCCGTTATCTCCGTCACATCTCCTTTGAACAAGAAAC
AGGTCTTCTTAGTGTAGGAGCAGGTGAGTTTTTGCCACGTCTTGCTTGGAAGGCAGCTAGAATGGGTTGGCAAGGTTTAG
AATGGGCCGTTGGTATCCCTGGCACTGTTGGTGGTGCTGTGGTGATGAATGCTGGGGCACAAGGTAAATGTATGGCTGAT
GTATTAGTGAATGCCCATGTTATTTTACCTAATGGTGAGATAGATATTTTGTCTCCTCAAGATTTGGAATACAATTACCG
CTATTCTAAATTGCAAGGTAAATCTATTTTGGTCGCTCAAGCTACATTTCAGTTACAACCGGGAGAAAAGCCTGCCTTAA
TAACGGCCATAACTTCTGAAAATTTTCAGAAGCGAAAAAGTACCCAGCCTTATCATTTACCTAGCTGTGGTAGTGTTTTT
CGGAATCCTGGACCAAAGACTGCTGGTTGGTTAATTGAACAAGCTGGACTTAAGGGCTATCAAATAGGTATGGCCCAAGT
TGCTCACCGCCATGCTAACTTTATTCTGAACTGTGGTGGAGCTACAGCTAACGAAATTTTACAGCTAATTTACCATGTTC
AAGAACAGGTGGAAAAGCAATGGTCTTTGTTATTAAAACCAGAGGTAAAATTTGTGGGAGATTTTTAA

Upstream 100 bases:

>100_bases
GCAAAATATTTCGGCACGGAAATGGTAAAAGCTGATAGGTAGTTAACTAACTTCAAAACAAACTCCTTAAATTACGATAA
TTCAAGCATTAGTTATCACC

Downstream 100 bases:

>100_bases
GAAGTAGCAAGCTTATAATTACAATAAAGCATAGCTTTTGTTTGACAATAGTTGTATAATTTAGGACCACAAATAAACTA
CATAAAATCTATAAATTATC

Product: UDP-N-acetylmuramate dehydrogenase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTLSYHIASSEKMPQRQPIPLLGKDCVIKSNVPLAPLTSFRVGGPAEWYVTPKRLDQLQASFQFANYKGLPITFLGAGSN
ILVSDSGLSGLVIGSRYLRHISFEQETGLLSVGAGEFLPRLAWKAARMGWQGLEWAVGIPGTVGGAVVMNAGAQGKCMAD
VLVNAHVILPNGEIDILSPQDLEYNYRYSKLQGKSILVAQATFQLQPGEKPALITAITSENFQKRKSTQPYHLPSCGSVF
RNPGPKTAGWLIEQAGLKGYQIGMAQVAHRHANFILNCGGATANEILQLIYHVQEQVEKQWSLLLKPEVKFVGDF

Sequences:

>Translated_315_residues
MTLSYHIASSEKMPQRQPIPLLGKDCVIKSNVPLAPLTSFRVGGPAEWYVTPKRLDQLQASFQFANYKGLPITFLGAGSN
ILVSDSGLSGLVIGSRYLRHISFEQETGLLSVGAGEFLPRLAWKAARMGWQGLEWAVGIPGTVGGAVVMNAGAQGKCMAD
VLVNAHVILPNGEIDILSPQDLEYNYRYSKLQGKSILVAQATFQLQPGEKPALITAITSENFQKRKSTQPYHLPSCGSVF
RNPGPKTAGWLIEQAGLKGYQIGMAQVAHRHANFILNCGGATANEILQLIYHVQEQVEKQWSLLLKPEVKFVGDF
>Mature_314_residues
TLSYHIASSEKMPQRQPIPLLGKDCVIKSNVPLAPLTSFRVGGPAEWYVTPKRLDQLQASFQFANYKGLPITFLGAGSNI
LVSDSGLSGLVIGSRYLRHISFEQETGLLSVGAGEFLPRLAWKAARMGWQGLEWAVGIPGTVGGAVVMNAGAQGKCMADV
LVNAHVILPNGEIDILSPQDLEYNYRYSKLQGKSILVAQATFQLQPGEKPALITAITSENFQKRKSTQPYHLPSCGSVFR
NPGPKTAGWLIEQAGLKGYQIGMAQVAHRHANFILNCGGATANEILQLIYHVQEQVEKQWSLLLKPEVKFVGDF

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=330, Percent_Identity=28.1818181818182, Blast_Score=104, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 34345; Mature: 34214

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSYHIASSEKMPQRQPIPLLGKDCVIKSNVPLAPLTSFRVGGPAEWYVTPKRLDQLQA
CEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHH
SFQFANYKGLPITFLGAGSNILVSDSGLSGLVIGSRYLRHISFEQETGLLSVGAGEFLPR
HHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEHHHHHHHCCCCCCCCEEEECCHHHHHH
LAWKAARMGWQGLEWAVGIPGTVGGAVVMNAGAQGKCMADVLVNAHVILPNGEIDILSPQ
HHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCEEEECCC
DLEYNYRYSKLQGKSILVAQATFQLQPGEKPALITAITSENFQKRKSTQPYHLPSCGSVF
CCCCCEEEEEECCCEEEEEEEEEEECCCCCCEEEEEECCCCHHHHHCCCCCCCCCHHHHH
RNPGPKTAGWLIEQAGLKGYQIGMAQVAHRHANFILNCGGATANEILQLIYHVQEQVEKQ
CCCCCCCHHHHHHHCCCCCEEEHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
WSLLLKPEVKFVGDF
HHEEECCCEEEECCC
>Mature Secondary Structure 
TLSYHIASSEKMPQRQPIPLLGKDCVIKSNVPLAPLTSFRVGGPAEWYVTPKRLDQLQA
EEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHH
SFQFANYKGLPITFLGAGSNILVSDSGLSGLVIGSRYLRHISFEQETGLLSVGAGEFLPR
HHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEHHHHHHHCCCCCCCCEEEECCHHHHHH
LAWKAARMGWQGLEWAVGIPGTVGGAVVMNAGAQGKCMADVLVNAHVILPNGEIDILSPQ
HHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCEEEECCC
DLEYNYRYSKLQGKSILVAQATFQLQPGEKPALITAITSENFQKRKSTQPYHLPSCGSVF
CCCCCEEEEEECCCEEEEEEEEEEECCCCCCEEEEEECCCCHHHHHCCCCCCCCCHHHHH
RNPGPKTAGWLIEQAGLKGYQIGMAQVAHRHANFILNCGGATANEILQLIYHVQEQVEKQ
CCCCCCCHHHHHHHCCCCCEEEHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
WSLLLKPEVKFVGDF
HHEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA