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The map label for this gene is murC [H]

Identifier: 113477459

GI number: 113477459

Start: 6227282

End: 6228952

Strand: Reverse

Name: murC [H]

Synonym: Tery_4029

Alternate gene names: 113477459

Gene position: 6228952-6227282 (Counterclockwise)

Preceding gene: 113477461

Following gene: 113477458

Centisome position: 80.37

GC content: 36.92

Gene sequence:

>1671_bases
ATGATATCGCGTGTTAAGGGTGTGGTGTGTGTGGATTTTAAGGAGCAATTAATGAGTAAATATGTTGATTTAACTGGTAA
ACCATTTCATTTTATTGGTATTGGGGGCATCGGAATGTCTGCTCTTGCTTATATTTTAGCTAAACGCAAGTTGCCTACTT
ATGGCTCCGATATCAAATCAAGCCATATAACAAGACGCTTAGAAGCAATAGGAGCCCACATATTCTGGCACCAAGAAGCA
AAAAATTTAGAGTTATTTCAGCAAACTACTGAAGAACAAAATTTATTTCTGTCAAACAATTCAAGCTTAAATTTATCTCA
ATTTACTCCTTGCATAAGTCTAGGAGAAGTAACAACAAAAAAACATAATGTCAAATTAGAAAATCACAAAGGAATTTCTC
AACTACCACAAGTAGTTTGTTCAACAGCAATTAATACAACAAACTCTGAGTATAAGGCAGCAGTTGAACTTGGATGTCCA
ATTTTTCATCGCTCAGATTTATTGGCAGCCCTAATTCAGGATTATCAAAGTATAGCTGTAGCTGGTACCCATGGCAAAAC
TACAACTAGCAGCTTAATTGGGTTTATGCTTTTAGAGGCTGGTTTGGACCCCACCATTGTTATTGGTGGAGAAGTAGACG
CCTGGGGAGGTAATGCTCGTTTGGGTAGAAGTCCTTATCTGGTGGCAGAAGCAGACGAGTCGGATGGCTCTTTAGTTAAA
TTATCTGCTCATATTGGTGTAGTGACCAATATTGAGTTAGACCATCCAGACCATTATGATAGTTTGGATCAAGTGGTAGA
AATTTTCCAAGTTTTTAAAGAAAACTGCCAAAATCTAGTAGGTTGTATTGACTGCTCTACAGTTAGAGAAAAACTCCAGC
CAACTATTAGTTATAGTATTAACTTCGAAAGTGACGCTCACTATAAAGTAGATTGTGTACATTACCAATCTAATGTTACC
TTAGCTCGTGTTTGGGAAAAAGGCCAAATTTTGGGACAATTAAAGTTGAGGTTATTGGGTAAACATAATTTAAGTAATGC
TTTGGCAGCAGTGGCAGTAGGTAGATTATTAGGTTTAGAATTTTCTACTATTACCTCGGCGATCGCTCTTTTTGAAGGTG
CTCATCGTCGTTTTGAATATCGAGGAGAGTGCAATGGTATTGTATTTGTTGATGACTATGCTCATCATCCCAGTGAAATT
AATGCAACTCTAGCAGCGGCTAACTTACAAAAAAATCAGGAATTAAGTCCCAAGCCTCATATATCAACAAAAAAATTAAC
ACTCAAAACACAAAATAACTCATTGAAGATCGAAAGAGTTGTTGCTATATTCCAACCTCATCGTTATAGTCGTACTCAGG
CTTTTATTTCTGAGTTTGCTCAATCTTTTAATGACGCTGACATGGTAATTGTTACCAATATCTACAGTGCAGGAGAATCA
TCTGAGGGTCAAATTAACAGCCAACAAGTAGCTGAAGCTATTTCTAGGTATCATCGACAAGTTTACTATCGATCATCTTT
AGACTCAGTAAGTAAATTTTTGTACCAAGTTCTTAAACCAGGAGATTTGGCAATATTTCTAAGTGCGGGTAACCTAAATC
AGATTATCCCAGAACTTATGGCACGTTATCAACAACCTCACTACCAGGTCAAGTCTTGTGAAATAGCCTAA

Upstream 100 bases:

>100_bases
CAAACAGATTAATCACAAGATTATAGAGACTATTCACAAAGGTAATCAATGTTTTGAATAAATTACTGCTAAACTCTATC
TAAAAAAAAAAAATACTGCT

Downstream 100 bases:

>100_bases
TGAAGAATATGAATTTGAGCCAAAGAAGCACTCAACACTCAGCATTCAGTTCATTTTTTTTGACATTTATAAGTTGGTTT
CAACCACTTCTACATCATCC

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MISRVKGVVCVDFKEQLMSKYVDLTGKPFHFIGIGGIGMSALAYILAKRKLPTYGSDIKSSHITRRLEAIGAHIFWHQEA
KNLELFQQTTEEQNLFLSNNSSLNLSQFTPCISLGEVTTKKHNVKLENHKGISQLPQVVCSTAINTTNSEYKAAVELGCP
IFHRSDLLAALIQDYQSIAVAGTHGKTTTSSLIGFMLLEAGLDPTIVIGGEVDAWGGNARLGRSPYLVAEADESDGSLVK
LSAHIGVVTNIELDHPDHYDSLDQVVEIFQVFKENCQNLVGCIDCSTVREKLQPTISYSINFESDAHYKVDCVHYQSNVT
LARVWEKGQILGQLKLRLLGKHNLSNALAAVAVGRLLGLEFSTITSAIALFEGAHRRFEYRGECNGIVFVDDYAHHPSEI
NATLAAANLQKNQELSPKPHISTKKLTLKTQNNSLKIERVVAIFQPHRYSRTQAFISEFAQSFNDADMVIVTNIYSAGES
SEGQINSQQVAEAISRYHRQVYYRSSLDSVSKFLYQVLKPGDLAIFLSAGNLNQIIPELMARYQQPHYQVKSCEIA

Sequences:

>Translated_556_residues
MISRVKGVVCVDFKEQLMSKYVDLTGKPFHFIGIGGIGMSALAYILAKRKLPTYGSDIKSSHITRRLEAIGAHIFWHQEA
KNLELFQQTTEEQNLFLSNNSSLNLSQFTPCISLGEVTTKKHNVKLENHKGISQLPQVVCSTAINTTNSEYKAAVELGCP
IFHRSDLLAALIQDYQSIAVAGTHGKTTTSSLIGFMLLEAGLDPTIVIGGEVDAWGGNARLGRSPYLVAEADESDGSLVK
LSAHIGVVTNIELDHPDHYDSLDQVVEIFQVFKENCQNLVGCIDCSTVREKLQPTISYSINFESDAHYKVDCVHYQSNVT
LARVWEKGQILGQLKLRLLGKHNLSNALAAVAVGRLLGLEFSTITSAIALFEGAHRRFEYRGECNGIVFVDDYAHHPSEI
NATLAAANLQKNQELSPKPHISTKKLTLKTQNNSLKIERVVAIFQPHRYSRTQAFISEFAQSFNDADMVIVTNIYSAGES
SEGQINSQQVAEAISRYHRQVYYRSSLDSVSKFLYQVLKPGDLAIFLSAGNLNQIIPELMARYQQPHYQVKSCEIA
>Mature_556_residues
MISRVKGVVCVDFKEQLMSKYVDLTGKPFHFIGIGGIGMSALAYILAKRKLPTYGSDIKSSHITRRLEAIGAHIFWHQEA
KNLELFQQTTEEQNLFLSNNSSLNLSQFTPCISLGEVTTKKHNVKLENHKGISQLPQVVCSTAINTTNSEYKAAVELGCP
IFHRSDLLAALIQDYQSIAVAGTHGKTTTSSLIGFMLLEAGLDPTIVIGGEVDAWGGNARLGRSPYLVAEADESDGSLVK
LSAHIGVVTNIELDHPDHYDSLDQVVEIFQVFKENCQNLVGCIDCSTVREKLQPTISYSINFESDAHYKVDCVHYQSNVT
LARVWEKGQILGQLKLRLLGKHNLSNALAAVAVGRLLGLEFSTITSAIALFEGAHRRFEYRGECNGIVFVDDYAHHPSEI
NATLAAANLQKNQELSPKPHISTKKLTLKTQNNSLKIERVVAIFQPHRYSRTQAFISEFAQSFNDADMVIVTNIYSAGES
SEGQINSQQVAEAISRYHRQVYYRSSLDSVSKFLYQVLKPGDLAIFLSAGNLNQIIPELMARYQQPHYQVKSCEIA

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=429, Percent_Identity=33.5664335664336, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1790680, Length=451, Percent_Identity=26.8292682926829, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 61609; Mature: 61609

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRVKGVVCVDFKEQLMSKYVDLTGKPFHFIGIGGIGMSALAYILAKRKLPTYGSDIKS
CCCCCCCEEEECHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHH
SHITRRLEAIGAHIFWHQEAKNLELFQQTTEEQNLFLSNNSSLNLSQFTPCISLGEVTTK
HHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCEEEECCCCCCHHHCCCCEECCCCCCC
KHNVKLENHKGISQLPQVVCSTAINTTNSEYKAAVELGCPIFHRSDLLAALIQDYQSIAV
CCCEEECCCCCHHHHHHHHHHHHHCCCCCHHEEEHEECCCCCCHHHHHHHHHHHHHHEEE
AGTHGKTTTSSLIGFMLLEAGLDPTIVIGGEVDAWGGNARLGRSPYLVAEADESDGSLVK
ECCCCCCHHHHHHHHHHHHCCCCCEEEECCCEECCCCCCCCCCCCEEEEECCCCCCCEEE
LSAHIGVVTNIELDHPDHYDSLDQVVEIFQVFKENCQNLVGCIDCSTVREKLQPTISYSI
EEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEE
NFESDAHYKVDCVHYQSNVTLARVWEKGQILGQLKLRLLGKHNLSNALAAVAVGRLLGLE
EECCCCCEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
FSTITSAIALFEGAHRRFEYRGECNGIVFVDDYAHHPSEINATLAAANLQKNQELSPKPH
HHHHHHHHHHHHHHHHCEEECCCCCEEEEEECCCCCCCCCCCEEEEHHCCCCCCCCCCCC
ISTKKLTLKTQNNSLKIERVVAIFQPHRYSRTQAFISEFAQSFNDADMVIVTNIYSAGES
CCCEEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCC
SEGQINSQQVAEAISRYHRQVYYRSSLDSVSKFLYQVLKPGDLAIFLSAGNLNQIIPELM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
ARYQQPHYQVKSCEIA
HHHCCCCCCCCCCCCC
>Mature Secondary Structure
MISRVKGVVCVDFKEQLMSKYVDLTGKPFHFIGIGGIGMSALAYILAKRKLPTYGSDIKS
CCCCCCCEEEECHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHH
SHITRRLEAIGAHIFWHQEAKNLELFQQTTEEQNLFLSNNSSLNLSQFTPCISLGEVTTK
HHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCEEEECCCCCCHHHCCCCEECCCCCCC
KHNVKLENHKGISQLPQVVCSTAINTTNSEYKAAVELGCPIFHRSDLLAALIQDYQSIAV
CCCEEECCCCCHHHHHHHHHHHHHCCCCCHHEEEHEECCCCCCHHHHHHHHHHHHHHEEE
AGTHGKTTTSSLIGFMLLEAGLDPTIVIGGEVDAWGGNARLGRSPYLVAEADESDGSLVK
ECCCCCCHHHHHHHHHHHHCCCCCEEEECCCEECCCCCCCCCCCCEEEEECCCCCCCEEE
LSAHIGVVTNIELDHPDHYDSLDQVVEIFQVFKENCQNLVGCIDCSTVREKLQPTISYSI
EEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEE
NFESDAHYKVDCVHYQSNVTLARVWEKGQILGQLKLRLLGKHNLSNALAAVAVGRLLGLE
EECCCCCEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
FSTITSAIALFEGAHRRFEYRGECNGIVFVDDYAHHPSEINATLAAANLQKNQELSPKPH
HHHHHHHHHHHHHHHHCEEECCCCCEEEEEECCCCCCCCCCCEEEEHHCCCCCCCCCCCC
ISTKKLTLKTQNNSLKIERVVAIFQPHRYSRTQAFISEFAQSFNDADMVIVTNIYSAGES
CCCEEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCC
SEGQINSQQVAEAISRYHRQVYYRSSLDSVSKFLYQVLKPGDLAIFLSAGNLNQIIPELM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
ARYQQPHYQVKSCEIA
HHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA