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The map label for this gene is 113477027

Identifier: 113477027

GI number: 113477027

Start: 5434323

End: 5435174

Strand: Reverse

Name: 113477027

Synonym: Tery_3526

Alternate gene names: NA

Gene position: 5435174-5434323 (Counterclockwise)

Preceding gene: 113477028

Following gene: 113477026

Centisome position: 70.13

GC content: 31.57

Gene sequence:

>852_bases
ATGGTTTATACTCGTAAAAAATTAAATTTATCCGAGATTCAACTCTCTTATCTAGAATGGCAGCCAAAAGAAAATCAGGA
TAAAAAACAACCACTTTTATTATTACATGGTTTAGCAGATTCAGCTTTAGTCTGGCTAAACTTAGGAGAATATTTAGCAG
ATAAATATCATATTGTTGCCCCAGATATGCGCGGTCATGGAGAAAGTGGAAAACCAGAAAGTGGTTATAGTTTTGAGAAA
ACAATTACCGATTTAGAAGCATTAATGGAGAATTTAAACTGGTCCTCAGCTAATATTTTAGGTCATTCTTGGACAGGAAA
ATTAGCTTGTATTTGGGCAAAAAAAAATCCAGAAATATTTAAAAGTATGATTTTAGTAGACCCAGTTTTTATTGGGAAAA
TGCCTGGATTACTTAAAGTTACTTTTCCTATTCTTTATAGAACCTTAGAAACTCTTAAAGGCATGGGTCCATTTAATAGT
TTTACTGAGGCAGAAACTCAGGCAAAAGAGTTAGGAAAGTATAGGGGTTGGAGTAAAATTCAACAGATAGTTTTTCGGGA
AAGTCTTGAGAAAAAAACTAATGGAAAGTGGGGAAGTAAATTTGTTATTTCTGCTAGGAATGAAATTTTTGAGGAAGTGA
TGAAAGTTCCTGGTTTAACAGAATATATTGATGTACCAACCTTATTTATTCAACCAGAAAAAGGCGTCAATAAAAACAAT
CGACAAATGAAACCTTATGCTAAATATTTAAGGAAATTAAAAATAGAAAAAATTCCTGGAAATCATTGGGTATTTTTGGT
AGAACCAGAAAAATTTAATCAGAAAGTAGCAGAATTTTTAGAAAGCATTTGA

Upstream 100 bases:

>100_bases
TAATCTCAATCAGATAAAAGCAAGCCAAATACCAGAGCTAAAGAAGTAATAAATTTGCTATAATATTATCTTGCTAAATA
TTTAATCCTCATATTTGATT

Downstream 100 bases:

>100_bases
TATAATATTTAGGGATAACTAAAAAAATATTTTTAGGAGGTAGAGATTAAAAAAAAATTAGAAGTTAAAAGGAACAGGGA
ATTATAAAAGAAATATTCAG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: SEH; Cytosolic epoxide hydrolase; cEH; Epoxide hydratase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MVYTRKKLNLSEIQLSYLEWQPKENQDKKQPLLLLHGLADSALVWLNLGEYLADKYHIVAPDMRGHGESGKPESGYSFEK
TITDLEALMENLNWSSANILGHSWTGKLACIWAKKNPEIFKSMILVDPVFIGKMPGLLKVTFPILYRTLETLKGMGPFNS
FTEAETQAKELGKYRGWSKIQQIVFRESLEKKTNGKWGSKFVISARNEIFEEVMKVPGLTEYIDVPTLFIQPEKGVNKNN
RQMKPYAKYLRKLKIEKIPGNHWVFLVEPEKFNQKVAEFLESI

Sequences:

>Translated_283_residues
MVYTRKKLNLSEIQLSYLEWQPKENQDKKQPLLLLHGLADSALVWLNLGEYLADKYHIVAPDMRGHGESGKPESGYSFEK
TITDLEALMENLNWSSANILGHSWTGKLACIWAKKNPEIFKSMILVDPVFIGKMPGLLKVTFPILYRTLETLKGMGPFNS
FTEAETQAKELGKYRGWSKIQQIVFRESLEKKTNGKWGSKFVISARNEIFEEVMKVPGLTEYIDVPTLFIQPEKGVNKNN
RQMKPYAKYLRKLKIEKIPGNHWVFLVEPEKFNQKVAEFLESI
>Mature_283_residues
MVYTRKKLNLSEIQLSYLEWQPKENQDKKQPLLLLHGLADSALVWLNLGEYLADKYHIVAPDMRGHGESGKPESGYSFEK
TITDLEALMENLNWSSANILGHSWTGKLACIWAKKNPEIFKSMILVDPVFIGKMPGLLKVTFPILYRTLETLKGMGPFNS
FTEAETQAKELGKYRGWSKIQQIVFRESLEKKTNGKWGSKFVISARNEIFEEVMKVPGLTEYIDVPTLFIQPEKGVNKNN
RQMKPYAKYLRKLKIEKIPGNHWVFLVEPEKFNQKVAEFLESI

Specific function: Involved in catabolic degradation of epoxides. Shows highest activity towards C6 and C7 carbocyclic epoxides. Also active towards linear 1,2-epoxyalkanes [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR010497 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF06441 EHN [H]

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 32614; Mature: 32614

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYTRKKLNLSEIQLSYLEWQPKENQDKKQPLLLLHGLADSALVWLNLGEYLADKYHIVA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHHCCCEEEEC
PDMRGHGESGKPESGYSFEKTITDLEALMENLNWSSANILGHSWTGKLACIWAKKNPEIF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCHHHH
KSMILVDPVFIGKMPGLLKVTFPILYRTLETLKGMGPFNSFTEAETQAKELGKYRGWSKI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHH
QQIVFRESLEKKTNGKWGSKFVISARNEIFEEVMKVPGLTEYIDVPTLFIQPEKGVNKNN
HHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCCC
RQMKPYAKYLRKLKIEKIPGNHWVFLVEPEKFNQKVAEFLESI
CCCCHHHHHHHHHHHEECCCCEEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVYTRKKLNLSEIQLSYLEWQPKENQDKKQPLLLLHGLADSALVWLNLGEYLADKYHIVA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHHCCCEEEEC
PDMRGHGESGKPESGYSFEKTITDLEALMENLNWSSANILGHSWTGKLACIWAKKNPEIF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCHHHH
KSMILVDPVFIGKMPGLLKVTFPILYRTLETLKGMGPFNSFTEAETQAKELGKYRGWSKI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHH
QQIVFRESLEKKTNGKWGSKFVISARNEIFEEVMKVPGLTEYIDVPTLFIQPEKGVNKNN
HHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCCC
RQMKPYAKYLRKLKIEKIPGNHWVFLVEPEKFNQKVAEFLESI
CCCCHHHHHHHHHHHEECCCCEEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9578475 [H]