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The map label for this gene is pipB2 [H]

Identifier: 113474386

GI number: 113474386

Start: 826613

End: 827146

Strand: Reverse

Name: pipB2 [H]

Synonym: Tery_0522

Alternate gene names: 113474386

Gene position: 827146-826613 (Counterclockwise)

Preceding gene: 113474387

Following gene: 113474379

Centisome position: 10.67

GC content: 37.27

Gene sequence:

>534_bases
ATGGTTCCAAGTAAGCAAGAAAAACAAAATTTCATTGAGAATTTAGCCACAGGTTTCTATAACCTACTTGGCATAGAAAC
CCTGAACAATGAACAGCTTCACTTAGCTCTCGAAGAGGGCAGAAAAGACTTTCGCAGAACTCGATTAATTAAGCCCAATT
TATTCAAAGCCAAATTAGATGGGATCAACTTCACCGGAGTAAATCTCAACAAAGTGAATCTGAGTGAAGCTTCATTAATG
AACACACAATTACATAAAACAAAAATGTTAGGAGCTAACTTGGACTCAGCTAATCTGAAAGGGGCTAACCTCAGCCGAGC
CAACTTAAAAGATGCCCAACTATCCTGGGCAGATTTAAGAAATACAAATCTAAGTAATACTTTACTCTATAACGCTAATT
TAACAGGTGCAGACCTGGATAGATCATCAATTATGTCCGCTAAAAGGCTGTTTACCAAATTTGACCATGCTCGCTTACCT
TCTGGTGTATCTTTAGTAAGGTATTTTTGGTTCTTTATCAAATTATCCGCCTAA

Upstream 100 bases:

>100_bases
CTATTCAAAAAAAATATAACACCATCATAGGAAATCACTAATGTCTACCCAAAAATTACCAGTAAATTTCAAATATAAAC
TTGATCATGATAGCACAAAA

Downstream 100 bases:

>100_bases
GAATATCTGGTAGTGCGTCAGTAAAGTATGGGATAAGTAATTAAGCCGTTCTAACTCCAAATAGCGATCGCGTTCCTCAG
CTCTTTACGCAGCAGTATTT

Product: pentapeptide repeat-containing protein

Products: NA

Alternate protein names: Type III effector pipB2 [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MVPSKQEKQNFIENLATGFYNLLGIETLNNEQLHLALEEGRKDFRRTRLIKPNLFKAKLDGINFTGVNLNKVNLSEASLM
NTQLHKTKMLGANLDSANLKGANLSRANLKDAQLSWADLRNTNLSNTLLYNANLTGADLDRSSIMSAKRLFTKFDHARLP
SGVSLVRYFWFFIKLSA

Sequences:

>Translated_177_residues
MVPSKQEKQNFIENLATGFYNLLGIETLNNEQLHLALEEGRKDFRRTRLIKPNLFKAKLDGINFTGVNLNKVNLSEASLM
NTQLHKTKMLGANLDSANLKGANLSRANLKDAQLSWADLRNTNLSNTLLYNANLTGADLDRSSIMSAKRLFTKFDHARLP
SGVSLVRYFWFFIKLSA
>Mature_177_residues
MVPSKQEKQNFIENLATGFYNLLGIETLNNEQLHLALEEGRKDFRRTRLIKPNLFKAKLDGINFTGVNLNKVNLSEASLM
NTQLHKTKMLGANLDSANLKGANLSRANLKDAQLSWADLRNTNLSNTLLYNANLTGADLDRSSIMSAKRLFTKFDHARLP
SGVSLVRYFWFFIKLSA

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the

COG id: COG1357

COG function: function code S; Uncharacterized low-complexity proteins

Gene ontology:

Cell location: Secreted. Host membrane (By similarity). Note=Secreted via the type III secretion system 2 (SPI-2 TTSS), and delivered into the host cell (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 pentapeptide repeat domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001646 [H]

Pfam domain/function: PF00805 Pentapeptide [H]

EC number: NA

Molecular weight: Translated: 19975; Mature: 19975

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPSKQEKQNFIENLATGFYNLLGIETLNNEQLHLALEEGRKDFRRTRLIKPNLFKAKLD
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEC
GINFTGVNLNKVNLSEASLMNTQLHKTKMLGANLDSANLKGANLSRANLKDAQLSWADLR
CEEECCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCHHHHHC
NTNLSNTLLYNANLTGADLDRSSIMSAKRLFTKFDHARLPSGVSLVRYFWFFIKLSA
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECC
>Mature Secondary Structure
MVPSKQEKQNFIENLATGFYNLLGIETLNNEQLHLALEEGRKDFRRTRLIKPNLFKAKLD
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEC
GINFTGVNLNKVNLSEASLMNTQLHKTKMLGANLDSANLKGANLSRANLKDAQLSWADLR
CEEECCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCHHHHHC
NTNLSNTLLYNANLTGADLDRSSIMSAKRLFTKFDHARLPSGVSLVRYFWFFIKLSA
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA