Click here to switch to the map view.

The map label for this gene is dtd

Identifier: 113474313

GI number: 113474313

Start: 696402

End: 696863

Strand: Direct

Name: dtd

Synonym: Tery_0442

Alternate gene names: 113474313

Gene position: 696402-696863 (Clockwise)

Preceding gene: 113474312

Following gene: 113474314

Centisome position: 8.99

GC content: 32.47

Gene sequence:

>462_bases
ATGCGAGTTGTTATCCAAAGAGTTAATTTTTCTCAGGTAAAAGTAAATGAAGAAATTGTTGGTAAAATTGGCAAAGGATT
AAATTTGCTTGTCGCTATTTCCACAACTGATACAGAAGCAGAAATAGATTGGATAGTACGTAAATGTCTAGATCTGCGTT
TATTTCCTGACCCAGATAGTAATAATAACTTTTGGGAAAAATCTGTCAAAGATATAGATGGTGAATTGTTAATAGTTAGT
CAGTTTACTCTATATGGAGATTGCCGTAAAGGTCGTCGCCCATCTTTCGATAACTCTGCATCTCCTGAAGTTGCTAAACA
ACTTTATCAACTATTTGTAGAAAAATTAAAATTGAGTGGTTTAAAAGTAGCAACTGGTATTTTTGGAGCAATGATGCAAG
TTGAAATTGATAATGATGGTCCCGTAACTTTCTTGTTAGAAAAAGAAGCTAATAATAAATAA

Upstream 100 bases:

>100_bases
TAACCAAGGTTAATGTCTTAACCTATGCTTTAATTTGCTTATAAAAAATTCCTATAAATCAAAATAAATAATGATTTTTG
ACTTTTGACTTAAATAAATT

Downstream 100 bases:

>100_bases
TTATTATCAGTTAATAATATGGTAAAGGAAAATATAAATATTAAAATAGTAATTAATTTGTGAGAATAATCTAGTCATAA
ATTATCTAATAAAAAATGTA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MRVVIQRVNFSQVKVNEEIVGKIGKGLNLLVAISTTDTEAEIDWIVRKCLDLRLFPDPDSNNNFWEKSVKDIDGELLIVS
QFTLYGDCRKGRRPSFDNSASPEVAKQLYQLFVEKLKLSGLKVATGIFGAMMQVEIDNDGPVTFLLEKEANNK

Sequences:

>Translated_153_residues
MRVVIQRVNFSQVKVNEEIVGKIGKGLNLLVAISTTDTEAEIDWIVRKCLDLRLFPDPDSNNNFWEKSVKDIDGELLIVS
QFTLYGDCRKGRRPSFDNSASPEVAKQLYQLFVEKLKLSGLKVATGIFGAMMQVEIDNDGPVTFLLEKEANNK
>Mature_153_residues
MRVVIQRVNFSQVKVNEEIVGKIGKGLNLLVAISTTDTEAEIDWIVRKCLDLRLFPDPDSNNNFWEKSVKDIDGELLIVS
QFTLYGDCRKGRRPSFDNSASPEVAKQLYQLFVEKLKLSGLKVATGIFGAMMQVEIDNDGPVTFLLEKEANNK

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=153, Percent_Identity=43.1372549019608, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI1790320, Length=147, Percent_Identity=40.8163265306122, Blast_Score=114, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI115533292, Length=145, Percent_Identity=46.8965517241379, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319982, Length=151, Percent_Identity=41.0596026490066, Blast_Score=120, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281361569, Length=149, Percent_Identity=48.3221476510067, Blast_Score=125, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_TRIEI (Q119C3)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720374.1
- ProteinModelPortal:   Q119C3
- SMR:   Q119C3
- STRING:   Q119C3
- GeneID:   4242220
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0442
- NMPDR:   fig|203124.1.peg.4586
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q119C3
- ProtClustDB:   PRK05273
- BioCyc:   TERY203124:TERY_0442-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 17223; Mature: 17223

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVIQRVNFSQVKVNEEIVGKIGKGLNLLVAISTTDTEAEIDWIVRKCLDLRLFPDPDS
CEEEEEECCCCEEEECHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCEECCCCCC
NNNFWEKSVKDIDGELLIVSQFTLYGDCRKGRRPSFDNSASPEVAKQLYQLFVEKLKLSG
CCCHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
LKVATGIFGAMMQVEIDNDGPVTFLLEKEANNK
CCHHHHHHEEEEEEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRVVIQRVNFSQVKVNEEIVGKIGKGLNLLVAISTTDTEAEIDWIVRKCLDLRLFPDPDS
CEEEEEECCCCEEEECHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCEECCCCCC
NNNFWEKSVKDIDGELLIVSQFTLYGDCRKGRRPSFDNSASPEVAKQLYQLFVEKLKLSG
CCCHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
LKVATGIFGAMMQVEIDNDGPVTFLLEKEANNK
CCHHHHHHEEEEEEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA