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The map label for this gene is yciC [H]

Identifier: 113474312

GI number: 113474312

Start: 694774

End: 695922

Strand: Direct

Name: yciC [H]

Synonym: Tery_0441

Alternate gene names: 113474312

Gene position: 694774-695922 (Clockwise)

Preceding gene: 113474310

Following gene: 113474313

Centisome position: 8.96

GC content: 33.77

Gene sequence:

>1149_bases
ATGCAATTAACAACTACTCAGTTAGATAACTCAAATATAGACACCCCAAAACATGGTTTACCAGTGACAATAATTACAGG
TTTTCTGGGGAGTGGGAAGACTACTTTACTTAACCATATATTGCAAAACCAAGAGGGTGTTAAAACTGCTGTTTTGGTAA
ATGAATTTGGAGAAATTGGGATTGATAATGAGTTAATTGTTTCTACCAATGCAGATGACACAATGGTAGAACTTAGTAAT
GGTTGTGTTTGTTGCACTATTAATGAGGACTTGGTTAATGCAGTTTATAAGATTTTAGGAAAATCAGAAAAATTTGATTA
TATGGTAGTAGAAACTACTGGTTTAGCTGACCCATTGCCAGTAGCTTTAACCTTTTTAGGCACTGAGTTAAGAGATATGA
CTCGCTTAGATTCAATTATTACTTTGGTAGATGCTGCTAACTATAGTGTTGATTTGTTTAAGAGTCAAGCAGCACATAGT
CAAATTGTCTATAGTGATATTATTTTGTTGAATAAAACTGACTTGGCAGATGAAGCATATTTAGATTTATTGGAAGTGAA
AATTAGAAATCTTAAAAAAGATGCTAGAATTATTAGAACTAAGAAATCACAAGTAGCTTTACCATTAGTTCTGAGTGTTG
GTCTATTCGAGTCAGATAAGTATTTTGAGTTGGCAGAAGTTGATCAGCACCATAATCATGGCCATGACCATCATGATCAT
GATCATGAACACGAACATCATCACCATGACCATGAACACGAACATCATCACCATGACCATGGACATGAACATCATCACCA
TGACCATGGACATGAGCATCATCACCATGAACACGATCACTATCATTCTAACCATTTAGAAAATGATGGATTTACTTCTA
TTTCTTTTCAAAGTGATAAACCTCTTTCAATGAAGAAATTTCAACATTTTTTAGATAATAAATTACCAGCAAATGTTTTC
CGAGCTAAGGGTATTTTATGGTTTCAAGAAAGCTCTTTACGACACATATTTCACTTAAGTGGTAAGCGGTTTAGTATTGA
AGATGATCAGTGGAATGGTAATAATCATAAAAATCAGTTAGTTTTCATTGGTCAGAACTTAGACCATGAGAAGTTGCGAT
CGCAATTAAAAGATTGTGTTATCTCCTAA

Upstream 100 bases:

>100_bases
TAGAACAGCTTAAATTTTAATTTAAAGGTAAAACATGACTACTTTTTTTGTCATTAATACCAATTAACAATCAAGATTAA
CCTAATTTTAGAGGAAGACT

Downstream 100 bases:

>100_bases
AAAGTAATAAATAATGGCAATGGTGAAAAACCAATTTGTTCAAGTAATAAGGGCAGTAAAAAAAACTTGATTATGGGTGT
TTATCAGACAAATAGGATAA

Product: cobalamin synthesis protein, P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQLTTTQLDNSNIDTPKHGLPVTIITGFLGSGKTTLLNHILQNQEGVKTAVLVNEFGEIGIDNELIVSTNADDTMVELSN
GCVCCTINEDLVNAVYKILGKSEKFDYMVVETTGLADPLPVALTFLGTELRDMTRLDSIITLVDAANYSVDLFKSQAAHS
QIVYSDIILLNKTDLADEAYLDLLEVKIRNLKKDARIIRTKKSQVALPLVLSVGLFESDKYFELAEVDQHHNHGHDHHDH
DHEHEHHHHDHEHEHHHHDHGHEHHHHDHGHEHHHHEHDHYHSNHLENDGFTSISFQSDKPLSMKKFQHFLDNKLPANVF
RAKGILWFQESSLRHIFHLSGKRFSIEDDQWNGNNHKNQLVFIGQNLDHEKLRSQLKDCVIS

Sequences:

>Translated_382_residues
MQLTTTQLDNSNIDTPKHGLPVTIITGFLGSGKTTLLNHILQNQEGVKTAVLVNEFGEIGIDNELIVSTNADDTMVELSN
GCVCCTINEDLVNAVYKILGKSEKFDYMVVETTGLADPLPVALTFLGTELRDMTRLDSIITLVDAANYSVDLFKSQAAHS
QIVYSDIILLNKTDLADEAYLDLLEVKIRNLKKDARIIRTKKSQVALPLVLSVGLFESDKYFELAEVDQHHNHGHDHHDH
DHEHEHHHHDHEHEHHHHDHGHEHHHHDHGHEHHHHEHDHYHSNHLENDGFTSISFQSDKPLSMKKFQHFLDNKLPANVF
RAKGILWFQESSLRHIFHLSGKRFSIEDDQWNGNNHKNQLVFIGQNLDHEKLRSQLKDCVIS
>Mature_382_residues
MQLTTTQLDNSNIDTPKHGLPVTIITGFLGSGKTTLLNHILQNQEGVKTAVLVNEFGEIGIDNELIVSTNADDTMVELSN
GCVCCTINEDLVNAVYKILGKSEKFDYMVVETTGLADPLPVALTFLGTELRDMTRLDSIITLVDAANYSVDLFKSQAAHS
QIVYSDIILLNKTDLADEAYLDLLEVKIRNLKKDARIIRTKKSQVALPLVLSVGLFESDKYFELAEVDQHHNHGHDHHDH
DHEHEHHHHDHEHEHHHHDHGHEHHHHDHGHEHHHHEHDHYHSNHLENDGFTSISFQSDKPLSMKKFQHFLDNKLPANVF
RAKGILWFQESSLRHIFHLSGKRFSIEDDQWNGNNHKNQLVFIGQNLDHEKLRSQLKDCVIS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=251, Percent_Identity=37.8486055776892, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI126722884, Length=232, Percent_Identity=39.2241379310345, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI148727351, Length=232, Percent_Identity=38.7931034482759, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI146231952, Length=232, Percent_Identity=38.3620689655172, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI223941779, Length=197, Percent_Identity=40.6091370558376, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI223941776, Length=222, Percent_Identity=37.3873873873874, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI119120938, Length=130, Percent_Identity=44.6153846153846, Blast_Score=108, Evalue=9e-24,
Organism=Escherichia coli, GI87082430, Length=165, Percent_Identity=44.8484848484849, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788499, Length=160, Percent_Identity=36.25, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324356, Length=248, Percent_Identity=30.241935483871, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 43699; Mature: 43699

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTTTQLDNSNIDTPKHGLPVTIITGFLGSGKTTLLNHILQNQEGVKTAVLVNEFGEIG
CCCEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEHHHHHHHCCC
IDNELIVSTNADDTMVELSNGCVCCTINEDLVNAVYKILGKSEKFDYMVVETTGLADPLP
CCCCEEEECCCCCCEEEECCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
VALTFLGTELRDMTRLDSIITLVDAANYSVDLFKSQAAHSQIVYSDIILLNKTDLADEAY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEHEEEEEECCCCCHHHH
LDLLEVKIRNLKKDARIIRTKKSQVALPLVLSVGLFESDKYFELAEVDQHHNHGHDHHDH
HHHHHHHHHHHHHHHHHHHCCCCCEEEEHHEEECCCCCCCCEEHHHHHHHCCCCCCCCCC
DHEHEHHHHDHEHEHHHHDHGHEHHHHDHGHEHHHHEHDHYHSNHLENDGFTSISFQSDK
CCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEEEECCCC
PLSMKKFQHFLDNKLPANVFRAKGILWFQESSLRHIFHLSGKRFSIEDDQWNGNNHKNQL
CCHHHHHHHHHCCCCCHHHHHHCCEEEEECCCHHHHEEECCCEEECCCCCCCCCCCCCEE
VFIGQNLDHEKLRSQLKDCVIS
EEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLTTTQLDNSNIDTPKHGLPVTIITGFLGSGKTTLLNHILQNQEGVKTAVLVNEFGEIG
CCCEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEHHHHHHHCCC
IDNELIVSTNADDTMVELSNGCVCCTINEDLVNAVYKILGKSEKFDYMVVETTGLADPLP
CCCCEEEECCCCCCEEEECCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
VALTFLGTELRDMTRLDSIITLVDAANYSVDLFKSQAAHSQIVYSDIILLNKTDLADEAY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEHEEEEEECCCCCHHHH
LDLLEVKIRNLKKDARIIRTKKSQVALPLVLSVGLFESDKYFELAEVDQHHNHGHDHHDH
HHHHHHHHHHHHHHHHHHHCCCCCEEEEHHEEECCCCCCCCEEHHHHHHHCCCCCCCCCC
DHEHEHHHHDHEHEHHHHDHGHEHHHHDHGHEHHHHEHDHYHSNHLENDGFTSISFQSDK
CCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEEEECCCC
PLSMKKFQHFLDNKLPANVFRAKGILWFQESSLRHIFHLSGKRFSIEDDQWNGNNHKNQL
CCHHHHHHHHHCCCCCHHHHHHCCEEEEECCCHHHHEEECCCEEECCCCCCCCCCCCCEE
VFIGQNLDHEKLRSQLKDCVIS
EEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]