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The map label for this gene is acoC [H]

Identifier: 113474233

GI number: 113474233

Start: 543311

End: 544138

Strand: Direct

Name: acoC [H]

Synonym: Tery_0351

Alternate gene names: 113474233

Gene position: 543311-544138 (Clockwise)

Preceding gene: 113474228

Following gene: 113474235

Centisome position: 7.01

GC content: 32.49

Gene sequence:

>828_bases
ATGCAATCTGTATGGCTTAATTCTCGTGTAAAATTGTCTGATGGACTATTATTTTGGCGTGAAATTGGTACTGGTTCAAA
AAATATAGTTTTTCTACATGGAACTTGGTATGACAGTAGTCAGTGGTTATCAGTGATGGAAAAATTAAGTTTACATTACC
ATTGTTTTGCACCAGATTTACCTGGATGTAATGAGTCGAAATTTTATTCTACTTATTACTCAATTAGTCAAATGGTAGAA
TATTTAGCTGAATATATAGCTGCCTTGAAATTAGAAAAAGTTTATTTAGTTGGTCACTCTTTAGGAGGTTGGATAGCGGC
TAGCTATGGTCTTAAATATCCAGATAAATTATTGGGTTTGATTTTAGTATCCCCTGAAGGAATTGATATTGCTGATGTAA
AAGTACGTTGGCAGTGGTATCGCTGGTTAGCTCCGAAAGTTTCTTTGTTGTATTGGATGTTGCGATTAATATATCCTTTT
ACTAGGCTACTAGGTCTTAATAAGAAGGTTAAACAAATACTACAAATAAGACAAAATTTGCGTCTTAATTCAACAGTAAA
TCAAATTTTATTCCGGCGCCGTTGGGCACAGATAAAACATGAATTATTAGCAGAAAATTTAGGTTATTTAAAAGTAGCAA
CGTTGGTTTTACAAGGTTATAAAGATACGGATATTACTCTATCTATGAGTAAATACTGTGCTGAACTATTGCCGAGGGCT
AAACTTAGTTTAATTAGTTCTGGGGAGAGTAACTTACCTGAACAAATACCAGATATAGTAGTACAAAAAATTATAGATTT
TTTGAGTGACGAAGATAATTTATTATAG

Upstream 100 bases:

>100_bases
AACCTAGCACCTAAAACTTTTGTTCAGGATATCTACCATTACATAGGTAATGTTTAGGTATTTAGGTCAAATATTTGTGA
AATTTTCCCATTAAATATTT

Downstream 100 bases:

>100_bases
GAGTAGGAAGTAAAAGGTAGGTTTTAGGAGTAATAAATAATGGCGCTTTTCGCCTATAATTATTAAAGATATCGTTATTA
TTTACTTATTACTTAATAAC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system; Fast-migrating protein; FMP [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MQSVWLNSRVKLSDGLLFWREIGTGSKNIVFLHGTWYDSSQWLSVMEKLSLHYHCFAPDLPGCNESKFYSTYYSISQMVE
YLAEYIAALKLEKVYLVGHSLGGWIAASYGLKYPDKLLGLILVSPEGIDIADVKVRWQWYRWLAPKVSLLYWMLRLIYPF
TRLLGLNKKVKQILQIRQNLRLNSTVNQILFRRRWAQIKHELLAENLGYLKVATLVLQGYKDTDITLSMSKYCAELLPRA
KLSLISSGESNLPEQIPDIVVQKIIDFLSDEDNLL

Sequences:

>Translated_275_residues
MQSVWLNSRVKLSDGLLFWREIGTGSKNIVFLHGTWYDSSQWLSVMEKLSLHYHCFAPDLPGCNESKFYSTYYSISQMVE
YLAEYIAALKLEKVYLVGHSLGGWIAASYGLKYPDKLLGLILVSPEGIDIADVKVRWQWYRWLAPKVSLLYWMLRLIYPF
TRLLGLNKKVKQILQIRQNLRLNSTVNQILFRRRWAQIKHELLAENLGYLKVATLVLQGYKDTDITLSMSKYCAELLPRA
KLSLISSGESNLPEQIPDIVVQKIIDFLSDEDNLL
>Mature_275_residues
MQSVWLNSRVKLSDGLLFWREIGTGSKNIVFLHGTWYDSSQWLSVMEKLSLHYHCFAPDLPGCNESKFYSTYYSISQMVE
YLAEYIAALKLEKVYLVGHSLGGWIAASYGLKYPDKLLGLILVSPEGIDIADVKVRWQWYRWLAPKVSLLYWMLRLIYPF
TRLLGLNKKVKQILQIRQNLRLNSTVNQILFRRRWAQIKHELLAENLGYLKVATLVLQGYKDTDITLSMSKYCAELLPRA
KLSLISSGESNLPEQIPDIVVQKIIDFLSDEDNLL

Specific function: Dihydrolipoamide acetyltransferase involved in acetoin catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI189027141, Length=261, Percent_Identity=26.4367816091954, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558492, Length=194, Percent_Identity=28.3505154639175, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32566936, Length=194, Percent_Identity=28.3505154639175, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25146278, Length=143, Percent_Identity=32.1678321678322, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 31814; Mature: 31814

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVWLNSRVKLSDGLLFWREIGTGSKNIVFLHGTWYDSSQWLSVMEKLSLHYHCFAPDL
CCCCCCCCEEEECCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCC
PGCNESKFYSTYYSISQMVEYLAEYIAALKLEKVYLVGHSLGGWIAASYGLKYPDKLLGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHCCCCCHHHHHEE
ILVSPEGIDIADVKVRWQWYRWLAPKVSLLYWMLRLIYPFTRLLGLNKKVKQILQIRQNL
EEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
RLNSTVNQILFRRRWAQIKHELLAENLGYLKVATLVLQGYKDTDITLSMSKYCAELLPRA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCHH
KLSLISSGESNLPEQIPDIVVQKIIDFLSDEDNLL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQSVWLNSRVKLSDGLLFWREIGTGSKNIVFLHGTWYDSSQWLSVMEKLSLHYHCFAPDL
CCCCCCCCEEEECCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCC
PGCNESKFYSTYYSISQMVEYLAEYIAALKLEKVYLVGHSLGGWIAASYGLKYPDKLLGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHCCCCCHHHHHEE
ILVSPEGIDIADVKVRWQWYRWLAPKVSLLYWMLRLIYPFTRLLGLNKKVKQILQIRQNL
EEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
RLNSTVNQILFRRRWAQIKHELLAENLGYLKVATLVLQGYKDTDITLSMSKYCAELLPRA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCHH
KLSLISSGESNLPEQIPDIVVQKIIDFLSDEDNLL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2061286 [H]