Click here to switch to the map view.

The map label for this gene is arcB [H]

Identifier: 110636287

GI number: 110636287

Start: 4267192

End: 4268121

Strand: Reverse

Name: arcB [H]

Synonym: Meso_3963

Alternate gene names: 110636287

Gene position: 4268121-4267192 (Counterclockwise)

Preceding gene: 110636289

Following gene: 110636286

Centisome position: 96.73

GC content: 62.8

Gene sequence:

>930_bases
ATGCGTTGCAAAATCCTGGGGGCACCCGTTCAAGACGGTGCAGGGTGCAGAGGATGCGACATGGGCCCGAGCGCGCTTCG
CGTCGCGGGATTGGTCGAAGCATTGAGCGAGCTTGGCCACACAGTCGAGGATCTGGGCAATGTGAGCCCCAAGCTTCAGT
CTCCACTTGCCCATCCGAACTCAGTCCTCAGGTCATTATCCGAGATCGCCGGCTGGACCGCCGCTCTTGCAGAGGCGGCC
TATCGCGCCAGCGCCGACGCGCTGCCCATCTTTCTCGGCGGCGACCACAGCATATCCGCTGGAACGGTTTCCGGCATCGC
TCAACGGGCTGCAGAACTCAGGCGTCCGCTTTTCGTGTTATGGCTCGATGCGCACACCGATTTCCACACGCTGGACAGCA
CGGTGAGCGGCAACCTTCATGGGGTGCCGCTGGCCTATGCCACCGGACAACCGGGCTTCGACGGCTATTTCCCTCCGCTA
ATGGCCGCCGTCGATCCATTCCGCACCTGCGTAATGGGCATCCGCAGTATCGATCCCGCTGAACGTATCGCCATCAATGA
GGCGGGCGTGACCATGTACGATATGCGCGCCATCGACGAGCACGGCGTTGCGCCGCTTCTGCGCGCTTTTCTGGAGCGGG
TCGCCTCGCAGGACGGACTGCTGCATGTCAGCCTGGACGTCGACTTCCTCGATCCCTCGATCGCGCCGGCGGTCGGCACC
ACCGTGCCGGGCGGAGCGACCTTTCGCGAGGCACATCTGGTGATGGAAATGCTGCACGATAGCGGCCTCGTCAGCAGTCT
GGACCTGGTCGAGCTCAATCCCTTTCTCGATGAACGTGGCCGCACGGCAACCCTGATGGTCGATCTGGCCTCCAGCCTGA
TGGGACGCCGCATTATGGACCGGCCGACGCGGAGCTACTCACATGGATAA

Upstream 100 bases:

>100_bases
CAGAATGTAAATTATCACGCTCGCCTTGCCAAATCACGCCATATAAACCGCCGCGCGGTTCAGCTTTAATCCGCTGGAAA
AAGCTGCGAGACAAAAAGGC

Downstream 100 bases:

>100_bases
TTTGAATATCGTCCCCTTTGTCAGCGTCGATCACATGATGACGCTGGTGATGCGCACCGGCGTAGAGCAATTCCTGACCG
AACTTGCCGGCTATATCGAG

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRCKILGAPVQDGAGCRGCDMGPSALRVAGLVEALSELGHTVEDLGNVSPKLQSPLAHPNSVLRSLSEIAGWTAALAEAA
YRASADALPIFLGGDHSISAGTVSGIAQRAAELRRPLFVLWLDAHTDFHTLDSTVSGNLHGVPLAYATGQPGFDGYFPPL
MAAVDPFRTCVMGIRSIDPAERIAINEAGVTMYDMRAIDEHGVAPLLRAFLERVASQDGLLHVSLDVDFLDPSIAPAVGT
TVPGGATFREAHLVMEMLHDSGLVSSLDLVELNPFLDERGRTATLMVDLASSLMGRRIMDRPTRSYSHG

Sequences:

>Translated_309_residues
MRCKILGAPVQDGAGCRGCDMGPSALRVAGLVEALSELGHTVEDLGNVSPKLQSPLAHPNSVLRSLSEIAGWTAALAEAA
YRASADALPIFLGGDHSISAGTVSGIAQRAAELRRPLFVLWLDAHTDFHTLDSTVSGNLHGVPLAYATGQPGFDGYFPPL
MAAVDPFRTCVMGIRSIDPAERIAINEAGVTMYDMRAIDEHGVAPLLRAFLERVASQDGLLHVSLDVDFLDPSIAPAVGT
TVPGGATFREAHLVMEMLHDSGLVSSLDLVELNPFLDERGRTATLMVDLASSLMGRRIMDRPTRSYSHG
>Mature_309_residues
MRCKILGAPVQDGAGCRGCDMGPSALRVAGLVEALSELGHTVEDLGNVSPKLQSPLAHPNSVLRSLSEIAGWTAALAEAA
YRASADALPIFLGGDHSISAGTVSGIAQRAAELRRPLFVLWLDAHTDFHTLDSTVSGNLHGVPLAYATGQPGFDGYFPPL
MAAVDPFRTCVMGIRSIDPAERIAINEAGVTMYDMRAIDEHGVAPLLRAFLERVASQDGLLHVSLDVDFLDPSIAPAVGT
TVPGGATFREAHLVMEMLHDSGLVSSLDLVELNPFLDERGRTATLMVDLASSLMGRRIMDRPTRSYSHG

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=308, Percent_Identity=35.7142857142857, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI10947139, Length=299, Percent_Identity=33.1103678929766, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71996843, Length=240, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6325146, Length=296, Percent_Identity=31.0810810810811, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24638886, Length=310, Percent_Identity=30.9677419354839, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32804; Mature: 32804

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCKILGAPVQDGAGCRGCDMGPSALRVAGLVEALSELGHTVEDLGNVSPKLQSPLAHPN
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHH
SVLRSLSEIAGWTAALAEAAYRASADALPIFLGGDHSISAGTVSGIAQRAAELRRPLFVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEE
WLDAHTDFHTLDSTVSGNLHGVPLAYATGQPGFDGYFPPLMAAVDPFRTCVMGIRSIDPA
EEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
ERIAINEAGVTMYDMRAIDEHGVAPLLRAFLERVASQDGLLHVSLDVDFLDPSIAPAVGT
HHEEECCCCCEEEHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCC
TVPGGATFREAHLVMEMLHDSGLVSSLDLVELNPFLDERGRTATLMVDLASSLMGRRIMD
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHEECCHHHHCCCCEEEHHHHHHHHHHHHHHHC
RPTRSYSHG
CCCCCCCCC
>Mature Secondary Structure
MRCKILGAPVQDGAGCRGCDMGPSALRVAGLVEALSELGHTVEDLGNVSPKLQSPLAHPN
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHH
SVLRSLSEIAGWTAALAEAAYRASADALPIFLGGDHSISAGTVSGIAQRAAELRRPLFVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEE
WLDAHTDFHTLDSTVSGNLHGVPLAYATGQPGFDGYFPPLMAAVDPFRTCVMGIRSIDPA
EEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
ERIAINEAGVTMYDMRAIDEHGVAPLLRAFLERVASQDGLLHVSLDVDFLDPSIAPAVGT
HHEEECCCCCEEEHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCC
TVPGGATFREAHLVMEMLHDSGLVSSLDLVELNPFLDERGRTATLMVDLASSLMGRRIMD
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHEECCHHHHCCCCEEEHHHHHHHHHHHHHHHC
RPTRSYSHG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9375792 [H]