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The map label for this gene is ybiC [H]

Identifier: 110636289

GI number: 110636289

Start: 4268764

End: 4269828

Strand: Reverse

Name: ybiC [H]

Synonym: Meso_3965

Alternate gene names: 110636289

Gene position: 4269828-4268764 (Counterclockwise)

Preceding gene: 110636290

Following gene: 110636287

Centisome position: 96.77

GC content: 57.75

Gene sequence:

>1065_bases
ATGAACTCACAGCAGTTCTATGATGCGAACGCGTTGAAGGACTACGCCAGGAACCTTCTCAAGGCGCTGGACGTCCAGAC
TGATATCGCCGAAGTTGTGGCTGATGTCCTTGTTGAAGGAGATTTGCTGGGGCACAGCACACATGGCCTCGCACAGCTGC
CCAGCTATCTTGACAATCTAGCCAAGGGGCAGATGAAGCCTTCAGGGACTTATTCCGTGGTCAGTGATTTTCCAGCGGCC
ACCACATGGGATGGGCAGTGGCTGCCTGGCCCATGGCTGACAAGAACAGCATGTATTGAGGCAAAAACGCGCGCAAGAAA
GTTCGGCACAGGGACCGTTGTTATTCGCCGTTCACACCACATTGCATGTCTTGCGGCCTATCTCGAGCCGCTAACGGCCG
AAGGCTTTGTGTGCATTATCCAAAGCTCAGACCCCGCCGTCAAAGCAGTCGCGCCCCATGGCGGGACTCGTCCGTTTCTT
ACGCCAAATCCGGTCGCGGTTGGCATCCCGACGAAAGGTGATCCGATCCTGATCGACGTTTCCATGTCTATCGCGACTGT
CGGTATGGCACGACGTCTCATTGCTTCCGGTGAGCGGGCGCCTTTCCCTTGGTTGCTGGATGGCGATGGACATCCAACTG
ACGATCCCAACGTCATAGACGCCGACCCCAAGGGGAGCCTGATGCTGTTGGGAGGGATCGAGGCCGGGCACAAAGGCTTT
GGCTTGGCGCTTATGGTTGAAGCACTTACGGGCGGACTTGGTGGGCATGGTCGTGCTGACAAACCAACCAACTGGGGAGC
GTCGGTTTTCGTGCAGGTTCTAGATCCCGACGCATTCGGCGGGAAGGAGGCGCTCCTGAGGGAAATGAGTTTCATCGCCG
ACGAGTGTGTCTCCGGTCCGTCGCGCGATATCAACAACCCTGTAAGAATGCCCGGCTCGGCTGGCCTCAGGCGCAAGCGT
GAAGCTCTCGAGCGCGGCGTTCCCCTTCATTCCATCATAATGGAGAGCCTCACCCCATGGGGTGAACGTTTCGCCATATC
CGCCCCCCAACCAAGCGGCGCCTAA

Upstream 100 bases:

>100_bases
TCGCCCTTCTTCTTGTCAGCGTCTGGTCCATTCCGCTGATCTGGCGGCTTCGGCAGAAGGGAAGTGCGTCCATAACACGG
AGCTGAAAAGGGATATCCAA

Downstream 100 bases:

>100_bases
GCGCACGGCATGCGTGTTCGGCGATGGCGAAGCCCACGTCCTGCCTGCACGGCGGCGGCGGTACGCCTTGAAATTATAGT
TTGGCTTTGGTGCTGCGCGG

Product: malate/L-lactate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNSQQFYDANALKDYARNLLKALDVQTDIAEVVADVLVEGDLLGHSTHGLAQLPSYLDNLAKGQMKPSGTYSVVSDFPAA
TTWDGQWLPGPWLTRTACIEAKTRARKFGTGTVVIRRSHHIACLAAYLEPLTAEGFVCIIQSSDPAVKAVAPHGGTRPFL
TPNPVAVGIPTKGDPILIDVSMSIATVGMARRLIASGERAPFPWLLDGDGHPTDDPNVIDADPKGSLMLLGGIEAGHKGF
GLALMVEALTGGLGGHGRADKPTNWGASVFVQVLDPDAFGGKEALLREMSFIADECVSGPSRDINNPVRMPGSAGLRRKR
EALERGVPLHSIIMESLTPWGERFAISAPQPSGA

Sequences:

>Translated_354_residues
MNSQQFYDANALKDYARNLLKALDVQTDIAEVVADVLVEGDLLGHSTHGLAQLPSYLDNLAKGQMKPSGTYSVVSDFPAA
TTWDGQWLPGPWLTRTACIEAKTRARKFGTGTVVIRRSHHIACLAAYLEPLTAEGFVCIIQSSDPAVKAVAPHGGTRPFL
TPNPVAVGIPTKGDPILIDVSMSIATVGMARRLIASGERAPFPWLLDGDGHPTDDPNVIDADPKGSLMLLGGIEAGHKGF
GLALMVEALTGGLGGHGRADKPTNWGASVFVQVLDPDAFGGKEALLREMSFIADECVSGPSRDINNPVRMPGSAGLRRKR
EALERGVPLHSIIMESLTPWGERFAISAPQPSGA
>Mature_354_residues
MNSQQFYDANALKDYARNLLKALDVQTDIAEVVADVLVEGDLLGHSTHGLAQLPSYLDNLAKGQMKPSGTYSVVSDFPAA
TTWDGQWLPGPWLTRTACIEAKTRARKFGTGTVVIRRSHHIACLAAYLEPLTAEGFVCIIQSSDPAVKAVAPHGGTRPFL
TPNPVAVGIPTKGDPILIDVSMSIATVGMARRLIASGERAPFPWLLDGDGHPTDDPNVIDADPKGSLMLLGGIEAGHKGF
GLALMVEALTGGLGGHGRADKPTNWGASVFVQVLDPDAFGGKEALLREMSFIADECVSGPSRDINNPVRMPGSAGLRRKR
EALERGVPLHSIIMESLTPWGERFAISAPQPSGA

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=336, Percent_Identity=28.8690476190476, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786727, Length=336, Percent_Identity=25.297619047619, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790000, Length=307, Percent_Identity=22.8013029315961, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17507179, Length=318, Percent_Identity=29.559748427673, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17536633, Length=337, Percent_Identity=25.8160237388724, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667908, Length=283, Percent_Identity=28.9752650176678, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI45553211, Length=283, Percent_Identity=28.9752650176678, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24667912, Length=283, Percent_Identity=28.9752650176678, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24667904, Length=283, Percent_Identity=28.9752650176678, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648360, Length=357, Percent_Identity=24.3697478991597, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24658010, Length=311, Percent_Identity=24.7588424437299, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 37571; Mature: 37571

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQQFYDANALKDYARNLLKALDVQTDIAEVVADVLVEGDLLGHSTHGLAQLPSYLDNL
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AKGQMKPSGTYSVVSDFPAATTWDGQWLPGPWLTRTACIEAKTRARKFGTGTVVIRRSHH
HHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCC
IACLAAYLEPLTAEGFVCIIQSSDPAVKAVAPHGGTRPFLTPNPVAVGIPTKGDPILIDV
HHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCEEEEE
SMSIATVGMARRLIASGERAPFPWLLDGDGHPTDDPNVIDADPKGSLMLLGGIEAGHKGF
CHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCC
GLALMVEALTGGLGGHGRADKPTNWGASVFVQVLDPDAFGGKEALLREMSFIADECVSGP
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
SRDINNPVRMPGSAGLRRKREALERGVPLHSIIMESLTPWGERFAISAPQPSGA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MNSQQFYDANALKDYARNLLKALDVQTDIAEVVADVLVEGDLLGHSTHGLAQLPSYLDNL
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AKGQMKPSGTYSVVSDFPAATTWDGQWLPGPWLTRTACIEAKTRARKFGTGTVVIRRSHH
HHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCC
IACLAAYLEPLTAEGFVCIIQSSDPAVKAVAPHGGTRPFLTPNPVAVGIPTKGDPILIDV
HHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCEEEEE
SMSIATVGMARRLIASGERAPFPWLLDGDGHPTDDPNVIDADPKGSLMLLGGIEAGHKGF
CHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCC
GLALMVEALTGGLGGHGRADKPTNWGASVFVQVLDPDAFGGKEALLREMSFIADECVSGP
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
SRDINNPVRMPGSAGLRRKREALERGVPLHSIIMESLTPWGERFAISAPQPSGA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]