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The map label for this gene is intZ [H]

Identifier: 110632856

GI number: 110632856

Start: 551117

End: 552373

Strand: Direct

Name: intZ [H]

Synonym: Meso_0496

Alternate gene names: 110632856

Gene position: 551117-552373 (Clockwise)

Preceding gene: 110632855

Following gene: 110632858

Centisome position: 12.49

GC content: 62.77

Gene sequence:

>1257_bases
ATGTTGACGGATGCGGCACTCAAGTGCCTGAAACCAAAAGCCAAAATGTACAAGGTGACCGATCGTGACGGCATGTATGT
GCGTGTCGCGCCGACAGGCGGCATCTCGTTCAGGCTCGACTATCGGCTGAACGGCAGGCGGGAGACCGTCCATCTCGGCA
AGTACGCCCGAGATGGGATCTCGCTCGCCCGGGCGCGGGAATTGTGCCTGGACGCGAAACGCATGATTGCCGAGGGGCAG
TCCCCCGCCATCGAGAAGCAGCGGGAGAAGCGCCGGATCAAGGAGGCCAAGAGCTTCGGCGAGTTCGGCGAGAAGTGGCT
GACGGGCGCGCCCATGGCGGACAGTACGCGCGCCATGCGCCGCGCCATATTCGAGCGTGAACTCAAGCCGGTCTGGCAGA
ACCGTTTGCTGACCGAAATCACGCCTGATGACCTGCGCGCCCACTGCGCCAAGATCGTGGAACGGGGCGCGCCCGCGACG
GCCATCCATGTGCGGGATATCCTGAAGCAGATCTACGCCTTCGCCATCCTCCACGGCGAGAAGGTCGCGAACCCGGCCGA
TGACGTTGGTCCGGCTTCGATTGCCACGTTCACGCCCAAGGACCGGGCGCTTTCGCCGACCGAGATCCGCATCATGCTCA
AGCAACTGGAGCATGTCGCGACGCTGCCGACGATCCGGCTCGGCATGAAGCTCTACCTCCTCACCATGGTCCGGAAGAGC
GAACTGCAGGACGCGGTCTGGGATGAAGTCGATTTCGAAAACGCCGTCTGGACGATCCCGAAGGAGCGCATGAAGCGATC
GAAGCCGCACAACGTCTACCTGTGCCGGCAGACCCTCGACATCATGATCGCGCTCAAGACCTGCGCCGGTAATTCCCGGT
ATCTGCTGCCTTCCCGCTACGATGCGGATGCGCCGATGTCGCGGGCGACCTTCAACCGGGTCACTTACGCTGTCGTCGAA
CAGGCCAAGAAGGAGGGGCTGCCGCTGGAGCCGTTCACCGTGCATGACCTGCGCCGCACGGGCTCGACGCTCCTCAATGA
GCTGGGCTTCAACCGCGACTGGATCGAAAAGTGCCTGGCGCACGAGGACGGGCGTTCATCACGCGGCGTCTACAACAAGG
CCGAATACGAGGTTCAGCGTCGCCACATGATGCAGGAATGGGCCGACACCGTCGATGCCTGGGTCGAGGGGCGGAAGTAT
GTTCCGACGCTGCTGCCGACAATCATGCCGTCTATCGCGCTCGATCCTGCCCTTTGA

Upstream 100 bases:

>100_bases
ACGGTACTTTTTTCAGCCTAACACGCTGAATATAAACAGATATTCCCGTCAAAAGCCTTCAAAAACCGCGTGACGGTACT
TTTCCGCGAGGAGGCCCAGA

Downstream 100 bases:

>100_bases
CTGGGCGGGACTTGCGCTTGGTGACATCGGGATGCTGTGCGCGAGGGATTGGCTTCGCGCGCCGCGCCAGCAACCAGGCG
TGGACCTCGGCGAGGTCCCA

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MLTDAALKCLKPKAKMYKVTDRDGMYVRVAPTGGISFRLDYRLNGRRETVHLGKYARDGISLARARELCLDAKRMIAEGQ
SPAIEKQREKRRIKEAKSFGEFGEKWLTGAPMADSTRAMRRAIFERELKPVWQNRLLTEITPDDLRAHCAKIVERGAPAT
AIHVRDILKQIYAFAILHGEKVANPADDVGPASIATFTPKDRALSPTEIRIMLKQLEHVATLPTIRLGMKLYLLTMVRKS
ELQDAVWDEVDFENAVWTIPKERMKRSKPHNVYLCRQTLDIMIALKTCAGNSRYLLPSRYDADAPMSRATFNRVTYAVVE
QAKKEGLPLEPFTVHDLRRTGSTLLNELGFNRDWIEKCLAHEDGRSSRGVYNKAEYEVQRRHMMQEWADTVDAWVEGRKY
VPTLLPTIMPSIALDPAL

Sequences:

>Translated_418_residues
MLTDAALKCLKPKAKMYKVTDRDGMYVRVAPTGGISFRLDYRLNGRRETVHLGKYARDGISLARARELCLDAKRMIAEGQ
SPAIEKQREKRRIKEAKSFGEFGEKWLTGAPMADSTRAMRRAIFERELKPVWQNRLLTEITPDDLRAHCAKIVERGAPAT
AIHVRDILKQIYAFAILHGEKVANPADDVGPASIATFTPKDRALSPTEIRIMLKQLEHVATLPTIRLGMKLYLLTMVRKS
ELQDAVWDEVDFENAVWTIPKERMKRSKPHNVYLCRQTLDIMIALKTCAGNSRYLLPSRYDADAPMSRATFNRVTYAVVE
QAKKEGLPLEPFTVHDLRRTGSTLLNELGFNRDWIEKCLAHEDGRSSRGVYNKAEYEVQRRHMMQEWADTVDAWVEGRKY
VPTLLPTIMPSIALDPAL
>Mature_418_residues
MLTDAALKCLKPKAKMYKVTDRDGMYVRVAPTGGISFRLDYRLNGRRETVHLGKYARDGISLARARELCLDAKRMIAEGQ
SPAIEKQREKRRIKEAKSFGEFGEKWLTGAPMADSTRAMRRAIFERELKPVWQNRLLTEITPDDLRAHCAKIVERGAPAT
AIHVRDILKQIYAFAILHGEKVANPADDVGPASIATFTPKDRALSPTEIRIMLKQLEHVATLPTIRLGMKLYLLTMVRKS
ELQDAVWDEVDFENAVWTIPKERMKRSKPHNVYLCRQTLDIMIALKTCAGNSRYLLPSRYDADAPMSRATFNRVTYAVVE
QAKKEGLPLEPFTVHDLRRTGSTLLNELGFNRDWIEKCLAHEDGRSSRGVYNKAEYEVQRRHMMQEWADTVDAWVEGRKY
VPTLLPTIMPSIALDPAL

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=407, Percent_Identity=31.6953316953317, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788974, Length=407, Percent_Identity=30.958230958231, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1788690, Length=400, Percent_Identity=28.5, Blast_Score=145, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47666; Mature: 47666

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDAALKCLKPKAKMYKVTDRDGMYVRVAPTGGISFRLDYRLNGRRETVHLGKYARDGI
CCCHHHHHHHCCCCCEEEEECCCCEEEEEECCCCEEEEEEEEECCCCCEEEHHHHHHHHH
SLARARELCLDAKRMIAEGQSPAIEKQREKRRIKEAKSFGEFGEKWLTGAPMADSTRAMR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RAIFERELKPVWQNRLLTEITPDDLRAHCAKIVERGAPATAIHVRDILKQIYAFAILHGE
HHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCH
KVANPADDVGPASIATFTPKDRALSPTEIRIMLKQLEHVATLPTIRLGMKLYLLTMVRKS
HCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ELQDAVWDEVDFENAVWTIPKERMKRSKPHNVYLCRQTLDIMIALKTCAGNSRYLLPSRY
HHHHHHHHHCCCCCCEEECCHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCEEECCCCC
DADAPMSRATFNRVTYAVVEQAKKEGLPLEPFTVHDLRRTGSTLLNELGFNRDWIEKCLA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHC
HEDGRSSRGVYNKAEYEVQRRHMMQEWADTVDAWVEGRKYVPTLLPTIMPSIALDPAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLTDAALKCLKPKAKMYKVTDRDGMYVRVAPTGGISFRLDYRLNGRRETVHLGKYARDGI
CCCHHHHHHHCCCCCEEEEECCCCEEEEEECCCCEEEEEEEEECCCCCEEEHHHHHHHHH
SLARARELCLDAKRMIAEGQSPAIEKQREKRRIKEAKSFGEFGEKWLTGAPMADSTRAMR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RAIFERELKPVWQNRLLTEITPDDLRAHCAKIVERGAPATAIHVRDILKQIYAFAILHGE
HHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCH
KVANPADDVGPASIATFTPKDRALSPTEIRIMLKQLEHVATLPTIRLGMKLYLLTMVRKS
HCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ELQDAVWDEVDFENAVWTIPKERMKRSKPHNVYLCRQTLDIMIALKTCAGNSRYLLPSRY
HHHHHHHHHCCCCCCEEECCHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCEEECCCCC
DADAPMSRATFNRVTYAVVEQAKKEGLPLEPFTVHDLRRTGSTLLNELGFNRDWIEKCLA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHC
HEDGRSSRGVYNKAEYEVQRRHMMQEWADTVDAWVEGRKYVPTLLPTIMPSIALDPAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]