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The map label for this gene is ddpA [H]

Identifier: 110632764

GI number: 110632764

Start: 445567

End: 447246

Strand: Reverse

Name: ddpA [H]

Synonym: Meso_0403

Alternate gene names: 110632764

Gene position: 447246-445567 (Counterclockwise)

Preceding gene: 110632769

Following gene: 110632763

Centisome position: 10.14

GC content: 56.55

Gene sequence:

>1680_bases
ATGGGGAACGAAGCCATGACGCATCAAAGAAATGCACTGGGCTCTGGCAACTCGCTTAATGCAGGATCGAGCCGCCGCCA
GTTCTTGAGAGGGCTTGGTATTGCTGCATCTGTTGCAGCCACTGGGATTCCATTCCAGGTGCAAGCAGCGGAAGACGGAA
GGCTACTGCGACTAACCGGTACGGTTGGCGATCCTGATCCTCATCGGGCCACGGACATTCCGGGCTCGATCTTGATGTTT
AACCTGTACGATTTTCTTGTCCGTCCCGCCCAGGGCGGACAGATCCTGCCGGCCCTGGCGGAGTCATGGTCGACGTCCGA
AGACGGTCGGGCATACACCTTCACGCTCCGGAACGACGTGGTGTTTCACGACGGAGCCAAGCTGACTGCGGCTGACGTCG
TCTTCTCACTCAATCGCATCAAGACAATGAAACGCGGGTTTTCCGCGCTATTCGACTTTGTCGAAAGCGTCGAGAGTTCC
GGCGATTATGAAGTCGTCTTCCGGCTACGGGAGCCTTATTCGCCGTTCCTCAGCAGCCTTACCCGCTTGGCGATCGTCAA
CAGCGCGCTGATCCGGGCTAATTTAGCCGACGGCCAGTATGGCGACATGAAGGATTATGGGCAGGCGTTTCTGGGGCAAG
CCGACGCAGGGTCCGGGCCTTACACGCTCGCGCAGCACAACCCTCAGCAGGAAACAGTCCTCACCCTGTATCCGTCCTAC
CACCTCAAATTGGCTGAAGATGTTCCAAGCGAGGTACGGACCCTCTACAGCATCGACCCGGCGACGGTTCGCACAATCGC
AAGCCGGGGCGAGCTTGAACTGACAAGGGTCAGCCTTCCACCGGAGATCCTGGCCTCACTGGCGAGATTGGATGGCGTGA
AACTCGGCCAAGATCGCGGCACCGATATGATGCAGTTCAAGCTGAACATGATGAAGGCACCGACTGACGATCTGGAGTTC
CGCCGCGCCGTTAGCCTAGGATTCAACTATGAGGCTCTCTACAGCTTGCTGGATATCGCAGGCGTAAGCTCCGGTATTCC
CGCGAGAGGTCCTATCCCGCAAGGTGCCATGGGCTACAGCCAGGACGTGCCGATCATGAAGCGTGACCTTGAAGGCGCGA
AAGCTGCGCTGGCGCGGTCGAAATATGCCGGCGACGGTGCACCACCATTGACCGTGTTGTGGGCAAGTGAGTTTGCCCAG
GTCCAAAAATATGCGCTGCTCTTTCAGAGCAGCATGGCTGAAGTGGGGATAAAGGTGGAGTTGTCTCCGGCACCTTGGGC
GCAGTACCAGAAAATGATCACGACCGCGGAAACGACGCCTAACGTCTGTATGCTCTATGTCGGGCTAACCACGCCCGATA
TCGACTCGTTGTTCTGGCCCACCTACCACTCCTCGGCCGCAGGCACATACAACTCCATGCAATGGCTGCAAAACCCGGAA
ATCGACGAGGCTTTGGAGCGTGGCCGCGAAATTCTAGATCCGACGGCGCGGACAAAGCATTATCAGGAGTTGGCAAAGAA
AATATCCGATCTGTATCCTGCAATATTTGCCTATGACCGAATAAACGTGGTCGCAATGAATAAGCGTCTCAAAGCTCCGG
CTTTGGAAGATCTTAATCAGAGCATCCCCGTCTGGGGCGGAAACTACCAGTTCCGTATGATGGACATTTCTCGCGCCTGA

Upstream 100 bases:

>100_bases
TTAGAGTGACAATGCCTACCCGACCGACAGCGCCGCCTTGTGTTGCGGTCGTGGCGCCAAAACCTCTGCCTCGGCAAGTT
GGGACGGGAGGAAACTCTAA

Downstream 100 bases:

>100_bases
TTCATCAAGCACCGCGTCGGGCGCCCGCAATCGTGCGCCCGCTAGCGGTTAGTAAGAACTCCGGAAGTTCTCATCCATGT
TGTCTATCCTGCGCAGGTAT

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MGNEAMTHQRNALGSGNSLNAGSSRRQFLRGLGIAASVAATGIPFQVQAAEDGRLLRLTGTVGDPDPHRATDIPGSILMF
NLYDFLVRPAQGGQILPALAESWSTSEDGRAYTFTLRNDVVFHDGAKLTAADVVFSLNRIKTMKRGFSALFDFVESVESS
GDYEVVFRLREPYSPFLSSLTRLAIVNSALIRANLADGQYGDMKDYGQAFLGQADAGSGPYTLAQHNPQQETVLTLYPSY
HLKLAEDVPSEVRTLYSIDPATVRTIASRGELELTRVSLPPEILASLARLDGVKLGQDRGTDMMQFKLNMMKAPTDDLEF
RRAVSLGFNYEALYSLLDIAGVSSGIPARGPIPQGAMGYSQDVPIMKRDLEGAKAALARSKYAGDGAPPLTVLWASEFAQ
VQKYALLFQSSMAEVGIKVELSPAPWAQYQKMITTAETTPNVCMLYVGLTTPDIDSLFWPTYHSSAAGTYNSMQWLQNPE
IDEALERGREILDPTARTKHYQELAKKISDLYPAIFAYDRINVVAMNKRLKAPALEDLNQSIPVWGGNYQFRMMDISRA

Sequences:

>Translated_559_residues
MGNEAMTHQRNALGSGNSLNAGSSRRQFLRGLGIAASVAATGIPFQVQAAEDGRLLRLTGTVGDPDPHRATDIPGSILMF
NLYDFLVRPAQGGQILPALAESWSTSEDGRAYTFTLRNDVVFHDGAKLTAADVVFSLNRIKTMKRGFSALFDFVESVESS
GDYEVVFRLREPYSPFLSSLTRLAIVNSALIRANLADGQYGDMKDYGQAFLGQADAGSGPYTLAQHNPQQETVLTLYPSY
HLKLAEDVPSEVRTLYSIDPATVRTIASRGELELTRVSLPPEILASLARLDGVKLGQDRGTDMMQFKLNMMKAPTDDLEF
RRAVSLGFNYEALYSLLDIAGVSSGIPARGPIPQGAMGYSQDVPIMKRDLEGAKAALARSKYAGDGAPPLTVLWASEFAQ
VQKYALLFQSSMAEVGIKVELSPAPWAQYQKMITTAETTPNVCMLYVGLTTPDIDSLFWPTYHSSAAGTYNSMQWLQNPE
IDEALERGREILDPTARTKHYQELAKKISDLYPAIFAYDRINVVAMNKRLKAPALEDLNQSIPVWGGNYQFRMMDISRA
>Mature_558_residues
GNEAMTHQRNALGSGNSLNAGSSRRQFLRGLGIAASVAATGIPFQVQAAEDGRLLRLTGTVGDPDPHRATDIPGSILMFN
LYDFLVRPAQGGQILPALAESWSTSEDGRAYTFTLRNDVVFHDGAKLTAADVVFSLNRIKTMKRGFSALFDFVESVESSG
DYEVVFRLREPYSPFLSSLTRLAIVNSALIRANLADGQYGDMKDYGQAFLGQADAGSGPYTLAQHNPQQETVLTLYPSYH
LKLAEDVPSEVRTLYSIDPATVRTIASRGELELTRVSLPPEILASLARLDGVKLGQDRGTDMMQFKLNMMKAPTDDLEFR
RAVSLGFNYEALYSLLDIAGVSSGIPARGPIPQGAMGYSQDVPIMKRDLEGAKAALARSKYAGDGAPPLTVLWASEFAQV
QKYALLFQSSMAEVGIKVELSPAPWAQYQKMITTAETTPNVCMLYVGLTTPDIDSLFWPTYHSSAAGTYNSMQWLQNPEI
DEALERGREILDPTARTKHYQELAKKISDLYPAIFAYDRINVVAMNKRLKAPALEDLNQSIPVWGGNYQFRMMDISRA

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=523, Percent_Identity=26.9598470363289, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1789966, Length=521, Percent_Identity=26.4875239923225, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787052, Length=500, Percent_Identity=23.6, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789887, Length=319, Percent_Identity=24.1379310344828, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787551, Length=503, Percent_Identity=24.4532803180915, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61371; Mature: 61240

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNEAMTHQRNALGSGNSLNAGSSRRQFLRGLGIAASVAATGIPFQVQAAEDGRLLRLTG
CCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCEEEEEEC
TVGDPDPHRATDIPGSILMFNLYDFLVRPAQGGQILPALAESWSTSEDGRAYTFTLRNDV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHCCCCCCCCCEEEEEEECCE
VFHDGAKLTAADVVFSLNRIKTMKRGFSALFDFVESVESSGDYEVVFRLREPYSPFLSSL
EEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
TRLAIVNSALIRANLADGQYGDMKDYGQAFLGQADAGSGPYTLAQHNPQQETVLTLYPSY
HHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEEECCCC
HLKLAEDVPSEVRTLYSIDPATVRTIASRGELELTRVSLPPEILASLARLDGVKLGQDRG
CEEEHHCCCHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCEECCCCC
TDMMQFKLNMMKAPTDDLEFRRAVSLGFNYEALYSLLDIAGVSSGIPARGPIPQGAMGYS
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QDVPIMKRDLEGAKAALARSKYAGDGAPPLTVLWASEFAQVQKYALLFQSSMAEVGIKVE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEE
LSPAPWAQYQKMITTAETTPNVCMLYVGLTTPDIDSLFWPTYHSSAAGTYNSMQWLQNPE
ECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC
IDEALERGREILDPTARTKHYQELAKKISDLYPAIFAYDRINVVAMNKRLKAPALEDLNQ
HHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCC
SIPVWGGNYQFRMMDISRA
CCCCCCCCEEEEEEEECCC
>Mature Secondary Structure 
GNEAMTHQRNALGSGNSLNAGSSRRQFLRGLGIAASVAATGIPFQVQAAEDGRLLRLTG
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCEEEEEEC
TVGDPDPHRATDIPGSILMFNLYDFLVRPAQGGQILPALAESWSTSEDGRAYTFTLRNDV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHCCCCCCCCCEEEEEEECCE
VFHDGAKLTAADVVFSLNRIKTMKRGFSALFDFVESVESSGDYEVVFRLREPYSPFLSSL
EEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
TRLAIVNSALIRANLADGQYGDMKDYGQAFLGQADAGSGPYTLAQHNPQQETVLTLYPSY
HHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEEECCCC
HLKLAEDVPSEVRTLYSIDPATVRTIASRGELELTRVSLPPEILASLARLDGVKLGQDRG
CEEEHHCCCHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCEECCCCC
TDMMQFKLNMMKAPTDDLEFRRAVSLGFNYEALYSLLDIAGVSSGIPARGPIPQGAMGYS
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QDVPIMKRDLEGAKAALARSKYAGDGAPPLTVLWASEFAQVQKYALLFQSSMAEVGIKVE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEE
LSPAPWAQYQKMITTAETTPNVCMLYVGLTTPDIDSLFWPTYHSSAAGTYNSMQWLQNPE
ECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC
IDEALERGREILDPTARTKHYQELAKKISDLYPAIFAYDRINVVAMNKRLKAPALEDLNQ
HHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCC
SIPVWGGNYQFRMMDISRA
CCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]