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The map label for this gene is ispA [H]

Identifier: 109947621

GI number: 109947621

Start: 940923

End: 941834

Strand: Reverse

Name: ispA [H]

Synonym: Hac_1086

Alternate gene names: 109947621

Gene position: 941834-940923 (Counterclockwise)

Preceding gene: 109947622

Following gene: 109947620

Centisome position: 60.61

GC content: 35.53

Gene sequence:

>912_bases
ATGAATAACCCTAATTTATCCTTTTATTATAACGAGTGCGAGCGTTTTGAAAGCTTTTTAAAAAACCATCGTCTACACCT
TGAAAGCTTCCACCCTTATTTGGAAAAAGCCTTTTTTGAAATGGTGCTTAATGGAGGCAAAAGGTTTCGCCCCAAGCTTT
TTTTAGCCGTGCTTTGTGCTTTAGTGGGTAAAAAAGATTATTTAAACCAACAAACAGAATATTTTAAAATCGCTTTAAGT
ATTGAATGCTTGCACACTTATTCGCTTATCCATGACGATTTACCTTGCATGGATAATGCCGCTTTAAGAAGAAACCACCC
CACTTTACACGCTAAATACAATGAAACTTCAGCCGTTTTAATAGGCGATGCGCTCAACACTTACTCTTTTGAATTGCTCT
CAAACGCTTCATTAGAAAGTCACATTATTGTGGAGTTGGTCAAAATCTTAAGTGCTAATGGGGGGATTAAAGGCATGATC
TTAGGGCAAGCTTTGGATTGCTATTTTGAAAACACGCCCTTAAATTTAGAGCAACTCACTTTCTTACACGAGCATAAAAC
TGCTAAATTGGTTAGTGCAAGCTTGATCATGGGGCTTGTTGCCAGCGGTAATAAAGATGAAGAGCTTTCCAAGTGGCTTC
AAGATTTTGGTTTAAAAATAGGTCTTTGCTTTCAAGTGTTAGATGATATTATAGATGTTACACAAGATGAAAAAGAAAGC
GGTAAAACCACTCATTTAGATAGCGCTAAAAACAGCTTTGTGAATTTATTGGGGCTAGAAAAAGCAAGCGATTACGCTCA
AACTTTAAAAACAGAGATTTTAAACGATTTGAATGCATTAAAACCCACTCATATTTTGTTGAAAGAAAATTTGAACATAT
TGTTAAACACTCTATTTAAAGGCAAAACATGA

Upstream 100 bases:

>100_bases
GATCATTAAAACAAGTGCGTTAAAAGGCCTATTCAAAAAAGACCCTAAAACTAGAGCTGAATTTATGCAACTCTTAAAAT
CTTAGGCTATAATTCTATGC

Downstream 100 bases:

>100_bases
AAAAAATTTTACTCACTAACGATGATGGCTATCATGCAAAAGGCATTAAAGCTTTAGAACAAGCCCTAGAGAAGATGGCA
GAAATTTATGTGGTCGCCCC

Product: geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MNNPNLSFYYNECERFESFLKNHRLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGKKDYLNQQTEYFKIALS
IECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYNETSAVLIGDALNTYSFELLSNASLESHIIVELVKILSANGGIKGMI
LGQALDCYFENTPLNLEQLTFLHEHKTAKLVSASLIMGLVASGNKDEELSKWLQDFGLKIGLCFQVLDDIIDVTQDEKES
GKTTHLDSAKNSFVNLLGLEKASDYAQTLKTEILNDLNALKPTHILLKENLNILLNTLFKGKT

Sequences:

>Translated_303_residues
MNNPNLSFYYNECERFESFLKNHRLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGKKDYLNQQTEYFKIALS
IECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYNETSAVLIGDALNTYSFELLSNASLESHIIVELVKILSANGGIKGMI
LGQALDCYFENTPLNLEQLTFLHEHKTAKLVSASLIMGLVASGNKDEELSKWLQDFGLKIGLCFQVLDDIIDVTQDEKES
GKTTHLDSAKNSFVNLLGLEKASDYAQTLKTEILNDLNALKPTHILLKENLNILLNTLFKGKT
>Mature_303_residues
MNNPNLSFYYNECERFESFLKNHRLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGKKDYLNQQTEYFKIALS
IECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYNETSAVLIGDALNTYSFELLSNASLESHIIVELVKILSANGGIKGMI
LGQALDCYFENTPLNLEQLTFLHEHKTAKLVSASLIMGLVASGNKDEELSKWLQDFGLKIGLCFQVLDDIIDVTQDEKES
GKTTHLDSAKNSFVNLLGLEKASDYAQTLKTEILNDLNALKPTHILLKENLNILLNTLFKGKT

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=254, Percent_Identity=37.4015748031496, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789578, Length=242, Percent_Identity=29.3388429752066, Blast_Score=85, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17505681, Length=227, Percent_Identity=25.5506607929515, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 34285; Mature: 34285

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPNLSFYYNECERFESFLKNHRLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCA
CCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVGKKDYLNQQTEYFKIALSIECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYNETSAVL
HHCCHHHHCCCHHHEEEEEEHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCEEE
IGDALNTYSFELLSNASLESHIIVELVKILSANGGIKGMILGQALDCYFENTPLNLEQLT
EECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCHHHHH
FLHEHKTAKLVSASLIMGLVASGNKDEELSKWLQDFGLKIGLCFQVLDDIIDVTQDEKES
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHC
GKTTHLDSAKNSFVNLLGLEKASDYAQTLKTEILNDLNALKPTHILLKENLNILLNTLFK
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHC
GKT
CCC
>Mature Secondary Structure
MNNPNLSFYYNECERFESFLKNHRLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCA
CCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVGKKDYLNQQTEYFKIALSIECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYNETSAVL
HHCCHHHHCCCHHHEEEEEEHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCEEE
IGDALNTYSFELLSNASLESHIIVELVKILSANGGIKGMILGQALDCYFENTPLNLEQLT
EECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCHHHHH
FLHEHKTAKLVSASLIMGLVASGNKDEELSKWLQDFGLKIGLCFQVLDDIIDVTQDEKES
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHC
GKTTHLDSAKNSFVNLLGLEKASDYAQTLKTEILNDLNALKPTHILLKENLNILLNTLFK
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHC
GKT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]