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The map label for this gene is surE

Identifier: 109947620

GI number: 109947620

Start: 940123

End: 940926

Strand: Reverse

Name: surE

Synonym: Hac_1085

Alternate gene names: 109947620

Gene position: 940926-940123 (Counterclockwise)

Preceding gene: 109947621

Following gene: 109947619

Centisome position: 60.55

GC content: 38.68

Gene sequence:

>804_bases
ATGAAAAAAATTTTACTCACTAACGATGATGGCTATCATGCAAAAGGCATTAAAGCTTTAGAACAAGCCCTAGAGAAGAT
GGCAGAAATTTATGTGGTCGCCCCCAAGCATGAAAAAAGTGCATGTTCGCAATGCATCACTATCACCACGCCTTTAAGAG
CCGAGAAAATTAAGGGCAAAGAAGGTAGGCATTATAGGATTGATGATGGCACGCCAAGCGATTGCGTGTATTTGGCTATC
AATGAGCTGTTTAAACATGTCTCTTTTGATTTAGTGATTTCAGGGATCAATCTTGGATCTAACATGGGCGAAGACACGAT
TTATTCTGGAACGGTAGCCGGAGCGATTGAAGGCACTATCCAAGGCGTGCCTTCCATTGCGATTTCTCAAATCCTTTCTA
ACAAAAATAAAAACACTCCCTTAAGTTTTGATCTAGCTCAAAAGATTATCCAAGATCTAGTCCAAAACATTTTCACCAAA
GGCTATCCTTTAAAAGGACGCAAACTCTTAAATGTGAATATCCCTAATTGCTCCTTACAAGAATATAAGGGTGAATGCAT
CACCCCTAAAGGCTATAGAGTGTATAAAAAAGAAGTGCATAGGCGCACAGACCCTAAAAATGAAAGCTATTTTTGGCTAG
GATTACACCCTTTAGAATGGCAAAAGCGTGAAAATGAAGAAAGATTCTCTGATTTTGACGCTGTTGTTTCAAATCATGTC
TCTATCACGCCTTTAAATTTGGATTTAACGAGTTATAGTGATTTGAAAAGCTTGGAATCTTGGCATAGGGGAATGTTAAA
GTGA

Upstream 100 bases:

>100_bases
AAACAGAGATTTTAAACGATTTGAATGCATTAAAACCCACTCATATTTTGTTGAAAGAAAATTTGAACATATTGTTAAAC
ACTCTATTTAAAGGCAAAAC

Downstream 100 bases:

>100_bases
GTAAAAATTACCGCTTGACTTTTTTAGGGCTACTTGTTGGGGTTCTTTTTTTCTTTAGTGCGTGTGAGTACCGCTTGCAT
ATGGGGTATTATTCAGAAGT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKKILLTNDDGYHAKGIKALEQALEKMAEIYVVAPKHEKSACSQCITITTPLRAEKIKGKEGRHYRIDDGTPSDCVYLAI
NELFKHVSFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFTK
GYPLKGRKLLNVNIPNCSLQEYKGECITPKGYRVYKKEVHRRTDPKNESYFWLGLHPLEWQKRENEERFSDFDAVVSNHV
SITPLNLDLTSYSDLKSLESWHRGMLK

Sequences:

>Translated_267_residues
MKKILLTNDDGYHAKGIKALEQALEKMAEIYVVAPKHEKSACSQCITITTPLRAEKIKGKEGRHYRIDDGTPSDCVYLAI
NELFKHVSFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFTK
GYPLKGRKLLNVNIPNCSLQEYKGECITPKGYRVYKKEVHRRTDPKNESYFWLGLHPLEWQKRENEERFSDFDAVVSNHV
SITPLNLDLTSYSDLKSLESWHRGMLK
>Mature_267_residues
MKKILLTNDDGYHAKGIKALEQALEKMAEIYVVAPKHEKSACSQCITITTPLRAEKIKGKEGRHYRIDDGTPSDCVYLAI
NELFKHVSFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFTK
GYPLKGRKLLNVNIPNCSLQEYKGECITPKGYRVYKKEVHRRTDPKNESYFWLGLHPLEWQKRENEERFSDFDAVVSNHV
SITPLNLDLTSYSDLKSLESWHRGMLK

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=259, Percent_Identity=36.2934362934363, Blast_Score=164, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_HELAH (Q17WX7)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664848.1
- ProteinModelPortal:   Q17WX7
- SMR:   Q17WX7
- STRING:   Q17WX7
- GeneID:   4177464
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1085
- NMPDR:   fig|382638.8.peg.1054
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- PhylomeDB:   Q17WX7
- ProtClustDB:   PRK00346
- BioCyc:   HACI382638:HAC_1085-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 30102; Mature: 30102

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLTNDDGYHAKGIKALEQALEKMAEIYVVAPKHEKSACSQCITITTPLRAEKIKGK
CCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHCEEEEECCCHHHHCCCC
EGRHYRIDDGTPSDCVYLAINELFKHVSFDLVISGINLGSNMGEDTIYSGTVAGAIEGTI
CCCEEECCCCCCCCEEHHHHHHHHHHCCEEEEEEECCCCCCCCCCCEECCCCHHHHHHHH
QGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFTKGYPLKGRKLLNVNIPNCSLQ
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHH
EYKGECITPKGYRVYKKEVHRRTDPKNESYFWLGLHPLEWQKRENEERFSDFDAVVSNHV
HHCCCEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHCCE
SITPLNLDLTSYSDLKSLESWHRGMLK
EEEEEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKILLTNDDGYHAKGIKALEQALEKMAEIYVVAPKHEKSACSQCITITTPLRAEKIKGK
CCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHCEEEEECCCHHHHCCCC
EGRHYRIDDGTPSDCVYLAINELFKHVSFDLVISGINLGSNMGEDTIYSGTVAGAIEGTI
CCCEEECCCCCCCCEEHHHHHHHHHHCCEEEEEEECCCCCCCCCCCEECCCCHHHHHHHH
QGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFTKGYPLKGRKLLNVNIPNCSLQ
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHH
EYKGECITPKGYRVYKKEVHRRTDPKNESYFWLGLHPLEWQKRENEERFSDFDAVVSNHV
HHCCCEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHCCE
SITPLNLDLTSYSDLKSLESWHRGMLK
EEEEEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA