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The map label for this gene is mur

Identifier: 109947601

GI number: 109947601

Start: 922785

End: 924053

Strand: Reverse

Name: mur

Synonym: Hac_1066

Alternate gene names: 109947601

Gene position: 924053-922785 (Counterclockwise)

Preceding gene: 109947602

Following gene: 109947600

Centisome position: 59.47

GC content: 43.89

Gene sequence:

>1269_bases
TTGGACTTTTTAGAGATTGTAGGACAAATCCCTTTAAAAGGGGGGGTAGAAATTTCTGGGGCTAAAAATTCCGCGCTCCC
CATTTTAGCCGCCACGCTTTTAAGCCAACAAGAAGTCACAATCAGCGCTTTGCCCCAAGTGGCTGACATCAAGGCAATGG
CGTCCTTGTTGCAAAATTTAGGTGCAGAGTTAGATTGGTTTAATTCTCACACGCTCAAACTTTGTGCTAAATCCCTACGC
CATACCGAAGCCACTTATGATTTGGTGCGTAAAATGCGCGCTTCTATTTTGGTTTTAGGCCCATTACTAGCACGCTTTAA
GGAATGTTTAGTGAGTTTGCCCGGTGGGTGTGCCATAGGGGCTAGGCCTGTGGATTTGCACTTAAAAGCGATGCAACAAT
TGGGGGCTGAAATCACGATTGAGCAAGGCTATATCCATGCAAAGGCTGCAAAGGGTTTAAAAGGCAATGATATTTTATTT
GATAAAATCAGTGTTACAGGCACAGAAAATGCCCTTATGGCAGCAAGTCTGGCTAAAGGGATTACGCGCATCATTAATGC
GGCTAAAGAGCCAGAAATCGCTCAATTGTGCACATTTTTACAAAGTGGGGGCGTAGAGATTGAAGGTGTTGGCAGCAGCG
AGTTGAAGATTAGAGGGGTAGAAAGCGATGCTTTGAGTTTAAAAGACATTCAAATCATACCCGATAGGATTGAAGCAGGC
ACTTATTTATGTGTAGGGGCTATCACTAACAGCCAGCTTAAAATTAATCATATCATCCCTAACCATCTCCAAGCGATCAC
AGACAAGCTTATAGAAATTGGTTTCCCGCTAGACATCCAACAAAATTCCATAGAAATTTATCCGGCCAAAAAACGCCAAG
CTTTTGAAATCACCACGAAAGAATACCCAGGCTTTCCCACAGACATGCAAGCGCAATTCATGGCGTTAGCCACGCAGTGT
TTGGGGACGAGCGTGATTGAAGAAACGCTTTTTGAAAACCGCTTCATGCACGCAAGCGAATTGCAACGATTGGGGGCAAA
TATTAGCCTAAAAACCAATATCGCTACCATTCACGGATCCACAGAGCTTACCGGGAGCGATGTGATGGCAACCGATTTAA
GGGCTTCTTCAGCTCTCATTTTAGCCGCTTTAGTGGCTAAAGGCGTGAGTAGGGTGCATAGGATTTACCACTTAGATAGG
GGTTATGAGAGATTAGAGGATAAAATCAACGCTTTAGGGGCAAAAGTGTTGCGTTTAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
ATTTTGGGCAGGATTTAGAAAACGCTAACCCCAACTACGCGCAAAAAATCGCTAACACTACCGGTTTAGCCCTTAAAAAT
AAAAAAGAAAAAGGATAGAA

Downstream 100 bases:

>100_bases
CCCAAGATTTGGCTACAATAACTAGAATATTTTTTAACGATACAAGGAGCTTTTATGCGTATTGAGCATGATTTCATTGG
AGAGATGGAAATTAGCGATG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDFLEIVGQIPLKGGVEISGAKNSALPILAATLLSQQEVTISALPQVADIKAMASLLQNLGAELDWFNSHTLKLCAKSLR
HTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEITIEQGYIHAKAAKGLKGNDILF
DKISVTGTENALMAASLAKGITRIINAAKEPEIAQLCTFLQSGGVEIEGVGSSELKIRGVESDALSLKDIQIIPDRIEAG
TYLCVGAITNSQLKINHIIPNHLQAITDKLIEIGFPLDIQQNSIEIYPAKKRQAFEITTKEYPGFPTDMQAQFMALATQC
LGTSVIEETLFENRFMHASELQRLGANISLKTNIATIHGSTELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDR
GYERLEDKINALGAKVLRLKEK

Sequences:

>Translated_422_residues
MDFLEIVGQIPLKGGVEISGAKNSALPILAATLLSQQEVTISALPQVADIKAMASLLQNLGAELDWFNSHTLKLCAKSLR
HTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEITIEQGYIHAKAAKGLKGNDILF
DKISVTGTENALMAASLAKGITRIINAAKEPEIAQLCTFLQSGGVEIEGVGSSELKIRGVESDALSLKDIQIIPDRIEAG
TYLCVGAITNSQLKINHIIPNHLQAITDKLIEIGFPLDIQQNSIEIYPAKKRQAFEITTKEYPGFPTDMQAQFMALATQC
LGTSVIEETLFENRFMHASELQRLGANISLKTNIATIHGSTELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDR
GYERLEDKINALGAKVLRLKEK
>Mature_422_residues
MDFLEIVGQIPLKGGVEISGAKNSALPILAATLLSQQEVTISALPQVADIKAMASLLQNLGAELDWFNSHTLKLCAKSLR
HTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEITIEQGYIHAKAAKGLKGNDILF
DKISVTGTENALMAASLAKGITRIINAAKEPEIAQLCTFLQSGGVEIEGVGSSELKIRGVESDALSLKDIQIIPDRIEAG
TYLCVGAITNSQLKINHIIPNHLQAITDKLIEIGFPLDIQQNSIEIYPAKKRQAFEITTKEYPGFPTDMQAQFMALATQC
LGTSVIEETLFENRFMHASELQRLGANISLKTNIATIHGSTELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDR
GYERLEDKINALGAKVLRLKEK

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=45.8432304038005, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_HELAH (Q17WZ6)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664829.1
- ProteinModelPortal:   Q17WZ6
- SMR:   Q17WZ6
- STRING:   Q17WZ6
- GeneID:   4176732
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1066
- NMPDR:   fig|382638.8.peg.1035
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q17WZ6
- ProtClustDB:   PRK09369
- BioCyc:   HACI382638:HAC_1066-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45681; Mature: 45681

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLEIVGQIPLKGGVEISGAKNSALPILAATLLSQQEVTISALPQVADIKAMASLLQNL
CCHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHC
GAELDWFNSHTLKLCAKSLRHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIG
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARPVDLHLKAMQQLGAEITIEQGYIHAKAAKGLKGNDILFDKISVTGTENALMAASLAKG
CCCHHHHHHHHHHCCCEEEEECCEEEEHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHH
ITRIINAAKEPEIAQLCTFLQSGGVEIEGVGSSELKIRGVESDALSLKDIQIIPDRIEAG
HHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCEEEECCHHCCC
TYLCVGAITNSQLKINHIIPNHLQAITDKLIEIGFPLDIQQNSIEIYPAKKRQAFEITTK
CEEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCEEEEECC
EYPGFPTDMQAQFMALATQCLGTSVIEETLFENRFMHASELQRLGANISLKTNIATIHGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEEEEECC
TELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDRGYERLEDKINALGAKVLRLK
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EK
CC
>Mature Secondary Structure
MDFLEIVGQIPLKGGVEISGAKNSALPILAATLLSQQEVTISALPQVADIKAMASLLQNL
CCHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHC
GAELDWFNSHTLKLCAKSLRHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIG
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARPVDLHLKAMQQLGAEITIEQGYIHAKAAKGLKGNDILFDKISVTGTENALMAASLAKG
CCCHHHHHHHHHHCCCEEEEECCEEEEHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHH
ITRIINAAKEPEIAQLCTFLQSGGVEIEGVGSSELKIRGVESDALSLKDIQIIPDRIEAG
HHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCEEEECCHHCCC
TYLCVGAITNSQLKINHIIPNHLQAITDKLIEIGFPLDIQQNSIEIYPAKKRQAFEITTK
CEEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCEEEEECC
EYPGFPTDMQAQFMALATQCLGTSVIEETLFENRFMHASELQRLGANISLKTNIATIHGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEEEEECC
TELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDRGYERLEDKINALGAKVLRLK
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA