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The map label for this gene is rlmH [H]

Identifier: 109947560

GI number: 109947560

Start: 890673

End: 891125

Strand: Reverse

Name: rlmH [H]

Synonym: Hac_1025

Alternate gene names: 109947560

Gene position: 891125-890673 (Counterclockwise)

Preceding gene: 109947561

Following gene: 109947559

Centisome position: 57.35

GC content: 34.88

Gene sequence:

>453_bases
ATGCGTTGTGTGGTGTATTCTATCGCTAAAAGTTCGCCTTTAGAATTGGTGAAAATTTATCAAAAGCAATGCAAACAATT
TGGTTGCGAGTTGGAATTAGTGGATTTATTCCCTAAAAACATAGCCAACGCTCAAAAAATTTCTAAAGAACTCGCTCAAA
AAAGCTACTCTCTAGCCTTTGAGCCGTATTTAAACCCTAAAGCAATAAATATTGCCTTACACCCTAAAGCTGAGAGAGGC
GATAGCTTTGCGTTTAGTAAAATGTTAGAAAATTATCTCAATATTAATTTCTTTATCGCTGGAGCGTATGGCTTTGAAGA
AAAATTTTTAAAAGATTGTCAAGCTTGGAGTTTGAGCGAGATGACTTTTAGCCATGAAGTGGCTAAGATTGTTTTATGCG
AGCAAATTTATAGGGCTTTAAGCATTATTTTTAGGCATCCATACCATAAATAG

Upstream 100 bases:

>100_bases
GATATGATTGTGCACAGAAAGGATTTGAAGAAAACTTTGAGCGATTTAATCGCTATGATGATGCATAAGACTTCAAAGGT
TTTTTAGAGTTTTAAGATTG

Downstream 100 bases:

>100_bases
GAGGTGCACATGCGTTTTTACATTATCTTTGCATTTTTGTTTATTGTGGGTTTTGGCGTGTTTGTTTATAGTATTGATCC
GCAAGCTTATGCTTTCAATT

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRCVVYSIAKSSPLELVKIYQKQCKQFGCELELVDLFPKNIANAQKISKELAQKSYSLAFEPYLNPKAINIALHPKAERG
DSFAFSKMLENYLNINFFIAGAYGFEEKFLKDCQAWSLSEMTFSHEVAKIVLCEQIYRALSIIFRHPYHK

Sequences:

>Translated_150_residues
MRCVVYSIAKSSPLELVKIYQKQCKQFGCELELVDLFPKNIANAQKISKELAQKSYSLAFEPYLNPKAINIALHPKAERG
DSFAFSKMLENYLNINFFIAGAYGFEEKFLKDCQAWSLSEMTFSHEVAKIVLCEQIYRALSIIFRHPYHK
>Mature_150_residues
MRCVVYSIAKSSPLELVKIYQKQCKQFGCELELVDLFPKNIANAQKISKELAQKSYSLAFEPYLNPKAINIALHPKAERG
DSFAFSKMLENYLNINFFIAGAYGFEEKFLKDCQAWSLSEMTFSHEVAKIVLCEQIYRALSIIFRHPYHK

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA [H]

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003742 [H]

Pfam domain/function: PF02590 SPOUT_MTase [H]

EC number: NA

Molecular weight: Translated: 17326; Mature: 17326

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCVVYSIAKSSPLELVKIYQKQCKQFGCELELVDLFPKNIANAQKISKELAQKSYSLAF
CCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEHHHCCHHCCHHHHHHHHHHHHHHCEEE
EPYLNPKAINIALHPKAERGDSFAFSKMLENYLNINFFIAGAYGFEEKFLKDCQAWSLSE
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCCHHH
MTFSHEVAKIVLCEQIYRALSIIFRHPYHK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRCVVYSIAKSSPLELVKIYQKQCKQFGCELELVDLFPKNIANAQKISKELAQKSYSLAF
CCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEHHHCCHHCCHHHHHHHHHHHHHHCEEE
EPYLNPKAINIALHPKAERGDSFAFSKMLENYLNINFFIAGAYGFEEKFLKDCQAWSLSE
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCCHHH
MTFSHEVAKIVLCEQIYRALSIIFRHPYHK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA