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The map label for this gene is accD [H]

Identifier: 109947561

GI number: 109947561

Start: 891139

End: 892008

Strand: Reverse

Name: accD [H]

Synonym: Hac_1026

Alternate gene names: 109947561

Gene position: 892008-891139 (Counterclockwise)

Preceding gene: 109947564

Following gene: 109947560

Centisome position: 57.4

GC content: 41.26

Gene sequence:

>870_bases
ATGGGATTTGCAGATTTCTTTAAAAACTTTAAGATAAATAAATTGCGAGAAGTACCGAGTAAGAACGAACAACCAAGCCA
TTGGGTGAAATGCCCTAAATGTTATGCGTTAATGTATTATAAAGAAGTGTTTGGCAAGCATAATGTGTGCTTGAAATGCC
ATTACCATTTCCGCATGAGTGCGACTGAAAGGATTGATCTTTTATGCGATGTGGGGAGTTTTCAAGAGTGCGACAAGTAT
TTATGGCCTAATGACCCTTTAAATTTTATTGATAAAGAAAGCTACAAGCAACGCATTAAAAAATACGAAAAAAGGACTAA
CCGCCCAAGCTCCGTGATCAGCGGTGAGGCTAAAATCAACCGCATGCCTTTACAGATCGTGGTGTTTGATTTTAGCTTTA
TGGGGGGGAGTTTAGGCTCTGTGGAGGGCGAAAAGATTGTAAGAGCGATCAATCGTGCGGTCACTAAAAAAGAAGCGTTA
TTGATTGTTTCAGCGAGTGGGGGGGCTAGGATGCAAGAATCCACTTATTCGCTTATGCAAATGGCTAAAACGAGTGCGGC
TTTGAATAGGTTAAGTGAGGCTAAGCTCCCTTTTATTTCGCTTTTAAGCGATCCCACTTATGGGGGCGTTAGTGCATCTT
TTGCTTTTTTAGGGGATTTAATCATCGCAGAGCCAGGGGCGATGATAGGTTTTGCAGGGCCTAGGGTGATTAAGCAAACT
ATAGGGGCGGATTTGCCTGAGGGCTTTCAAACAGCGGAATTTTTACTAGAGCATGGCTTGATTGATATGATTGTGCACAG
AAAGGATTTGAAGAAAACTTTGAGCGATTTAATCGCTATGATGATGCATAAGACTTCAAAGGTTTTTTAG

Upstream 100 bases:

>100_bases
AAAAGAAACCCTTGCATCACTACTCTTAAGCTAATTTTGTTTTATTATAAGCAAAACTTGGATACAATCACTAAGTAAAA
CTGCAAAATTAAGGAAAAAC

Downstream 100 bases:

>100_bases
AGTTTTAAGATTGATGCGTTGTGTGGTGTATTCTATCGCTAAAAGTTCGCCTTTAGAATTGGTGAAAATTTATCAAAAGC
AATGCAAACAATTTGGTTGC

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MGFADFFKNFKINKLREVPSKNEQPSHWVKCPKCYALMYYKEVFGKHNVCLKCHYHFRMSATERIDLLCDVGSFQECDKY
LWPNDPLNFIDKESYKQRIKKYEKRTNRPSSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVTKKEAL
LIVSASGGARMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQT
IGADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMMHKTSKVF

Sequences:

>Translated_289_residues
MGFADFFKNFKINKLREVPSKNEQPSHWVKCPKCYALMYYKEVFGKHNVCLKCHYHFRMSATERIDLLCDVGSFQECDKY
LWPNDPLNFIDKESYKQRIKKYEKRTNRPSSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVTKKEAL
LIVSASGGARMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQT
IGADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMMHKTSKVF
>Mature_288_residues
GFADFFKNFKINKLREVPSKNEQPSHWVKCPKCYALMYYKEVFGKHNVCLKCHYHFRMSATERIDLLCDVGSFQECDKYL
WPNDPLNFIDKESYKQRIKKYEKRTNRPSSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVTKKEALL
IVSASGGARMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQTI
GADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMMHKTSKVF

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=198, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI295821216, Length=218, Percent_Identity=26.605504587156, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788655, Length=256, Percent_Identity=49.609375, Blast_Score=256, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI25147362, Length=194, Percent_Identity=27.8350515463918, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25147359, Length=194, Percent_Identity=27.8350515463918, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 32575; Mature: 32444

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFADFFKNFKINKLREVPSKNEQPSHWVKCPKCYALMYYKEVFGKHNVCLKCHYHFRMS
CCHHHHHHCCCHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEEECC
ATERIDLLCDVGSFQECDKYLWPNDPLNFIDKESYKQRIKKYEKRTNRPSSVISGEAKIN
CHHHHHHEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
RMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVTKKEALLIVSASGGARMQESTYSLMQ
CCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
MAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQT
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
IGADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMMHKTSKVF
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GFADFFKNFKINKLREVPSKNEQPSHWVKCPKCYALMYYKEVFGKHNVCLKCHYHFRMS
CHHHHHHCCCHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEEECC
ATERIDLLCDVGSFQECDKYLWPNDPLNFIDKESYKQRIKKYEKRTNRPSSVISGEAKIN
CHHHHHHEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
RMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVTKKEALLIVSASGGARMQESTYSLMQ
CCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
MAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQT
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
IGADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMMHKTSKVF
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]