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The map label for this gene is yleA [C]

Identifier: 109947136

GI number: 109947136

Start: 469176

End: 470432

Strand: Direct

Name: yleA [C]

Synonym: Hac_0545

Alternate gene names: 109947136

Gene position: 469176-470432 (Clockwise)

Preceding gene: 109947135

Following gene: 109947137

Centisome position: 30.19

GC content: 37.31

Gene sequence:

>1257_bases
ATGAAAAAAGTCTATTTTAAAACTTTTGGGTGCAGAACGAATCTTTTTGACACGCAAGTGATGGGCGAGAATTTAAAGGA
TTTTAGCGCGACTTTAGAAGAAAATGAAGCGGATATTATTATTATCAATTCTTGCACCGTAACTAATGGGGCTGATAGCG
CGGTAAGGAGCTACGCTAAAAAAATGGTGCGTTTGAATAAGGAAGTGTTATTCACTGGCTGTGGGGTGAAAACTCAAGGC
AAAGAGCTTTTTGAAAAAGGGTTTTTAAAGGGCGTTTTTGGGCATGACAATAAAGAAAAGATCAATACGCTTTTACAAGA
AAAAAAGCGTTTTTTCATAGATGATAATTTAGAAAACAAGCACTTAGACACCACGATGGTGAGCGAGTTTGTGGGCAAGA
CTAGGGCGTTTATTAAGATTCAAGAGGGTTGTGATTTTGATTGCAATTATTGCATTATCCCAAGCGTGAGAGGGAGAGCT
AGGAGTTTTGAAGAAAGAAAAATTTTAGAGCAGGTGGGCCTTTTATGCGCTAAAGGGGTTCAAGAAGTGGTCTTAACCGG
CACTAATGTGGGGAGCTATGGGAAAGATAGAGAGAGTAATATCGCAAGATTGATTAAAAAATTAAGCCAAATTGTTGGAT
TAAAACGCATCAGAATTGGGAGCTTAGAGCCTAATCAAATCAACGATGAGTTTTTAGAGCTTTTAGAAGAGGATTTTTTA
GAAAAACATTTGCATATCGCTTTACAGCATAGTCATGACTTCATGTTAGAGAGGATGAACAGGAGGAATCGCGTGAAAAG
CGATAGGGAATTATTAGAGGTAATTGCTTCTAAAAATTTTGCTATCGGCACGGATTTTATTGTAGGGCATCCGGGCGAGA
GTGAAAGCGTTTTTGAAAAGGCGTTTGAAAATTTAGAGGGCTTGCCTTTAACGCATATCCACCCTTTTATTTATAGCAAA
CGAAAGGACACCCCTTCTAGTTTGATGCATGATAGCGTGAGTTTAGAAGTTTCTAAAAAGCGTTTGAATGCGATTAAAGA
TTTGATTTTTCATAAAAATAAGGTGTTCAGACAATTGCAACTCAAGCGTAACACGCCCCTAAAAGCTTTAGTGGAAGCGC
AAAAAGATGGCGAATTTAAAGCCTTGGATCAATTTTTTAACCCCATTAAAATCAAAAGCGATAAGCCTTTAAGGGCTAGT
TTTTTAGAAATCAAAGAGTATGAAATTAAGGAGAGAGAAAATTATGCCATTTTCTAA

Upstream 100 bases:

>100_bases
CTTTTTTGAAAGAAGAAAATATCCATATCGCTTATACCACCAGCAAATTGCTTAAAGTGGATACTGAGGGCGATGGCTTT
GGGAATAAAAGGTAACAAGA

Downstream 100 bases:

>100_bases
AAGTTTAGAAAATCTCATCAACCCTTTTAAACGCATCAAAAACCGCTCGCTTGTGTTGGCGTTAGGGTTTTTGATCCTTA
CTTTTTGCTTGCTTCTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEENEADIIIINSCTVTNGADSAVRSYAKKMVRLNKEVLFTGCGVKTQG
KELFEKGFLKGVFGHDNKEKINTLLQEKKRFFIDDNLENKHLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRA
RSFEERKILEQVGLLCAKGVQEVVLTGTNVGSYGKDRESNIARLIKKLSQIVGLKRIRIGSLEPNQINDEFLELLEEDFL
EKHLHIALQHSHDFMLERMNRRNRVKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEKAFENLEGLPLTHIHPFIYSK
RKDTPSSLMHDSVSLEVSKKRLNAIKDLIFHKNKVFRQLQLKRNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRAS
FLEIKEYEIKERENYAIF

Sequences:

>Translated_418_residues
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEENEADIIIINSCTVTNGADSAVRSYAKKMVRLNKEVLFTGCGVKTQG
KELFEKGFLKGVFGHDNKEKINTLLQEKKRFFIDDNLENKHLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRA
RSFEERKILEQVGLLCAKGVQEVVLTGTNVGSYGKDRESNIARLIKKLSQIVGLKRIRIGSLEPNQINDEFLELLEEDFL
EKHLHIALQHSHDFMLERMNRRNRVKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEKAFENLEGLPLTHIHPFIYSK
RKDTPSSLMHDSVSLEVSKKRLNAIKDLIFHKNKVFRQLQLKRNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRAS
FLEIKEYEIKERENYAIF
>Mature_418_residues
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEENEADIIIINSCTVTNGADSAVRSYAKKMVRLNKEVLFTGCGVKTQG
KELFEKGFLKGVFGHDNKEKINTLLQEKKRFFIDDNLENKHLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRA
RSFEERKILEQVGLLCAKGVQEVVLTGTNVGSYGKDRESNIARLIKKLSQIVGLKRIRIGSLEPNQINDEFLELLEEDFL
EKHLHIALQHSHDFMLERMNRRNRVKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEKAFENLEGLPLTHIHPFIYSK
RKDTPSSLMHDSVSLEVSKKRLNAIKDLIFHKNKVFRQLQLKRNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRAS
FLEIKEYEIKERENYAIF

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=429, Percent_Identity=25.4079254079254, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI28872782, Length=388, Percent_Identity=26.8041237113402, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI28872784, Length=388, Percent_Identity=26.8041237113402, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1786882, Length=392, Percent_Identity=27.8061224489796, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787057, Length=366, Percent_Identity=25.9562841530055, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17553146, Length=411, Percent_Identity=25.0608272506083, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71996771, Length=218, Percent_Identity=25.6880733944954, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356207, Length=388, Percent_Identity=28.3505154639175, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI19922432, Length=367, Percent_Identity=26.158038147139, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 48067; Mature: 48067

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS01305 MOAA_NIFB_PQQE ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEENEADIIIINSCTVTNGADSAVRSYAK
CCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHCCCCCCEEEEECEECCCCCHHHHHHHHH
KMVRLNKEVLFTGCGVKTQGKELFEKGFLKGVFGHDNKEKINTLLQEKKRFFIDDNLENK
HHHHHCHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCCCC
HLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRARSFEERKILEQVGLLCAKGV
CCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCH
QEVVLTGTNVGSYGKDRESNIARLIKKLSQIVGLKRIRIGSLEPNQINDEFLELLEEDFL
HHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCHHHEEECCCCCCCCCHHHHHHHHHHHH
EKHLHIALQHSHDFMLERMNRRNRVKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEK
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCEEEECCCCCHHHHHH
AFENLEGLPLTHIHPFIYSKRKDTPSSLMHDSVSLEVSKKRLNAIKDLIFHKNKVFRQLQ
HHHCCCCCCCHHCCHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRASFLEIKEYEIKERENYAIF
HHCCCCHHHHHHHHCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEENEADIIIINSCTVTNGADSAVRSYAK
CCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHCCCCCCEEEEECEECCCCCHHHHHHHHH
KMVRLNKEVLFTGCGVKTQGKELFEKGFLKGVFGHDNKEKINTLLQEKKRFFIDDNLENK
HHHHHCHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCCCC
HLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRARSFEERKILEQVGLLCAKGV
CCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCH
QEVVLTGTNVGSYGKDRESNIARLIKKLSQIVGLKRIRIGSLEPNQINDEFLELLEEDFL
HHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCHHHEEECCCCCCCCCHHHHHHHHHHHH
EKHLHIALQHSHDFMLERMNRRNRVKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEK
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCEEEECCCCCHHHHHH
AFENLEGLPLTHIHPFIYSKRKDTPSSLMHDSVSLEVSKKRLNAIKDLIFHKNKVFRQLQ
HHHCCCCCCCHHCCHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRNTPLKALVEAQKDGEFKALDQFFNPIKIKSDKPLRASFLEIKEYEIKERENYAIF
HHCCCCHHHHHHHHCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]