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The map label for this gene is menC [H]

Identifier: 108812281

GI number: 108812281

Start: 2395080

End: 2396051

Strand: Reverse

Name: menC [H]

Synonym: YPN_2119

Alternate gene names: 108812281

Gene position: 2396051-2395080 (Counterclockwise)

Preceding gene: 108812282

Following gene: 108812280

Centisome position: 52.84

GC content: 57.0

Gene sequence:

>972_bases
ATGCGCACGGCTACCCTTTACCGCTACAGTGTACCGATGGAAGCGGGGGTGATACTGCGCCATCAGCGGCTGAAAAGTCG
CGATGGGTTGCTGGTCAAATTACAGCAAGGTGAATTGAGCGGCTGGGGCGAAATTGCCCCGTTACCGGAATTCAGTCAAG
AAACACTGGATCAAGCCCAAGTGGCGGCAGAGTGTTGGCTGCAACACTGGGTCAGTGGTGTCGAATCGGATGACAGCGTG
TTGCCCTCCGTGGCTTTTGGTCTCAGTTGTGCGCAGGCCGAACTCAAGCAAACCTTACCGCTGTCAGCGGATTATCGCAA
AGCGCCACTGTGTACCGGCGATCCTGATGAGCTGTTTGCGGTACTCCAGGCATTGCCGGGTGAGAAGGTTGCCAAGGTGA
AGGTCGGGCTGTATGAAGCGGTGCGTGATGGCATGATCGTTAATGTTCTGTTGGAAGCCCTGCCTGATCTGACACTGCGG
CTGGACGCTAATCGCAGTTGGAGCCGAGCGAAGGCCGATGGGTTCGCGAAGTATGTCAATCCGGCGCTGCGTTCGCGTAT
TGCCTTTCTGGAGGAACCGTGCAAAACCCGCGCTGAATCCCGTGAGTTTGCTCAAGATACCGGTATTGCTATTGCCTGGG
ATGAAAGTGTGCGTGAGGCGGATTTTCAGGTTGAAGCCGAGCCGGGAGTGGCGGCAATTGTGATCAAACCAACGCTGGTG
GGCAGTCTTGCTCGCTGTCAGCAACTGGTTCAACAAGCGCATCAGGCCGGTTTGGTTGCGGTTATTAGCTCCAGTATTGA
ATCCAGTCTGGGTCTGACGCAATTGGCCCGTTTGGCCGCTTGGTTGACCCCCGTCACGGTTCCGGGGTTGGATACGCTGG
ACCTGATGCAGGCGCAAGTCGTGCGGCCGTGGCCAGACAGCCCGTTGCCGCTAATCACGACCGAGCAGTTGGGCGTGGTA
TGGCATCGTTAG

Upstream 100 bases:

>100_bases
CCACCATGCTGTTCTATATGACCGATGAAGGGCAGGAGGGGCGTAACGCATTCAATGAAAAACGCCAACCGGACTTCAGC
AAATTCAAGCGTAATCCGTA

Downstream 100 bases:

>100_bases
GCCATCCGCCTTGGGAGCATTGGCCTTGGCAGTATTGGGCCAATCTGCGGCCTCAAGCGCTCGCTATCCGTTCTGGGGGG
CAACGGATCAGTTGGCAACA

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MRTATLYRYSVPMEAGVILRHQRLKSRDGLLVKLQQGELSGWGEIAPLPEFSQETLDQAQVAAECWLQHWVSGVESDDSV
LPSVAFGLSCAQAELKQTLPLSADYRKAPLCTGDPDELFAVLQALPGEKVAKVKVGLYEAVRDGMIVNVLLEALPDLTLR
LDANRSWSRAKADGFAKYVNPALRSRIAFLEEPCKTRAESREFAQDTGIAIAWDESVREADFQVEAEPGVAAIVIKPTLV
GSLARCQQLVQQAHQAGLVAVISSSIESSLGLTQLARLAAWLTPVTVPGLDTLDLMQAQVVRPWPDSPLPLITTEQLGVV
WHR

Sequences:

>Translated_323_residues
MRTATLYRYSVPMEAGVILRHQRLKSRDGLLVKLQQGELSGWGEIAPLPEFSQETLDQAQVAAECWLQHWVSGVESDDSV
LPSVAFGLSCAQAELKQTLPLSADYRKAPLCTGDPDELFAVLQALPGEKVAKVKVGLYEAVRDGMIVNVLLEALPDLTLR
LDANRSWSRAKADGFAKYVNPALRSRIAFLEEPCKTRAESREFAQDTGIAIAWDESVREADFQVEAEPGVAAIVIKPTLV
GSLARCQQLVQQAHQAGLVAVISSSIESSLGLTQLARLAAWLTPVTVPGLDTLDLMQAQVVRPWPDSPLPLITTEQLGVV
WHR
>Mature_323_residues
MRTATLYRYSVPMEAGVILRHQRLKSRDGLLVKLQQGELSGWGEIAPLPEFSQETLDQAQVAAECWLQHWVSGVESDDSV
LPSVAFGLSCAQAELKQTLPLSADYRKAPLCTGDPDELFAVLQALPGEKVAKVKVGLYEAVRDGMIVNVLLEALPDLTLR
LDANRSWSRAKADGFAKYVNPALRSRIAFLEEPCKTRAESREFAQDTGIAIAWDESVREADFQVEAEPGVAAIVIKPTLV
GSLARCQQLVQQAHQAGLVAVISSSIESSLGLTQLARLAAWLTPVTVPGLDTLDLMQAQVVRPWPDSPLPLITTEQLGVV
WHR

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=317, Percent_Identity=66.2460567823344, Blast_Score=423, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 35298; Mature: 35298

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTATLYRYSVPMEAGVILRHQRLKSRDGLLVKLQQGELSGWGEIAPLPEFSQETLDQAQ
CCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
VAAECWLQHWVSGVESDDSVLPSVAFGLSCAQAELKQTLPLSADYRKAPLCTGDPDELFA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
VLQALPGEKVAKVKVGLYEAVRDGMIVNVLLEALPDLTLRLDANRSWSRAKADGFAKYVN
HHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHC
PALRSRIAFLEEPCKTRAESREFAQDTGIAIAWDESVREADFQVEAEPGVAAIVIKPTLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCEEECCCCEEEEEECHHHH
GSLARCQQLVQQAHQAGLVAVISSSIESSLGLTQLARLAAWLTPVTVPGLDTLDLMQAQV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VRPWPDSPLPLITTEQLGVVWHR
CCCCCCCCCCEEEECCCCCEECC
>Mature Secondary Structure
MRTATLYRYSVPMEAGVILRHQRLKSRDGLLVKLQQGELSGWGEIAPLPEFSQETLDQAQ
CCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
VAAECWLQHWVSGVESDDSVLPSVAFGLSCAQAELKQTLPLSADYRKAPLCTGDPDELFA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
VLQALPGEKVAKVKVGLYEAVRDGMIVNVLLEALPDLTLRLDANRSWSRAKADGFAKYVN
HHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHC
PALRSRIAFLEEPCKTRAESREFAQDTGIAIAWDESVREADFQVEAEPGVAAIVIKPTLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCEEECCCCEEEEEECHHHH
GSLARCQQLVQQAHQAGLVAVISSSIESSLGLTQLARLAAWLTPVTVPGLDTLDLMQAQV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VRPWPDSPLPLITTEQLGVVWHR
CCCCCCCCCCEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA