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The map label for this gene is secY [H]

Identifier: 108798019

GI number: 108798019

Start: 1144594

End: 1145919

Strand: Direct

Name: secY [H]

Synonym: Mmcs_1046

Alternate gene names: 108798019

Gene position: 1144594-1145919 (Clockwise)

Preceding gene: 108798015

Following gene: 108798020

Centisome position: 20.06

GC content: 63.73

Gene sequence:

>1326_bases
GTGCTTTCGGCTTTCATCTCGTCGCTGCGGACGGCTGACCTGAGGCGCAAGATCCTGTTCACGCTGGGTGTGGTCCTGCT
CTATCGGGTCGGCGCCTCGTTGCCGTCCCCCGGGGTCAACTACCCGAACGTGCAGGAGTGCATCGCACAGGTCAGCGGCG
GTGAATCGGGTCAGATCTATTCGCTGATCAATCTGTTCTCCGGTGGTGCGCTGCTCCAGCTGTCGGTGTTCGCGGTGGGC
GTCATGCCCTACATCACCGCGAGCATCATCGTGCAGCTGTTGACCGTGGTGATCCCGCGGTTCGAGCAGCTGCGCAAGGA
GGGCCAGGCCGGTCAGTCGAAGATGACGCAGTACACGCGTTATCTGGCGGTCGCGCTGGCGGTCCTGCAGTCCACCAGCA
TCGTCGCGCTGGCCGCCAACGGCGGTCTGCTGCAGGGCTGTGCGCTCGACATCATCGAGGATCAGGCGATCTTCTCGCTG
CTGGTCATCGTGCTGGTCATGACGGCGGGCGCCAGCCTGGTCATGTGGATGGGTGAGCTGGTCACCGAACGCGGTATCGG
CAACGGTATGTCGCTGATCATCTTCGCCAGCATCGCGGCGGCCATGCCGGGTGAGGGCAAGTCGATCCTGGACAGCCGCG
GCGGCATGGTGTTCGCAGCCGTCTGTGCGGGCGCGCTGATCATCATCATCGGCGTCGTCTTCGTCGAGCAGGGCCAGCGC
CGCATCCCGGTGCAGTACGCCAAGCGCATGGTCGGGCGCCGGATGTACGGCGGCACGTCGACCTACCTGCCGTTGAAGGT
CAACCAGGCCGGCGTCATCCCCGTCATCTTCGCCTCGTCGCTGATCTACATCCCGCACCTGGTCACCCAGTTGATCCAGA
GCGGCAGTTCCAATCCAGGCACCGGGTGGTGGGAACGTTTCGTCGCGGAGTACCTGACCGACCCGAGCAGCCCCTGGTAC
ATCGGGATCTACTTCGCGCTGATCATCTTCTTCACCTACTTCTACGTGTCCATCACGTTCAACCCGGACGAGCGGGCCGA
CGAGATGAAGAAGTTCGGCGGCTTCATCCCCGGTATCCGCCCCGGCAAGCCGACCGCCGACTACCTCCGTTACGTGCTGA
GCCGGATCACGCTGCCCGGCTCGATCTACCTGGGCTTGATCGCCGTGCTGCCCAACCTGTTCGCCAACGTCGGCAGCAGC
GGCCCCGTGCAGAACCTCCCCTTCGGCGGCGTCGGGGTGCTGATCATGATCGGCGTGGGTCTGGACACCGTGAAACAGAT
CGAAAGCCAGCTCATGCAGCGCAACTACGAGGGCTTTTTGAAGTGA

Upstream 100 bases:

>100_bases
TTCCTGTCCGAGACGGTGCGTGTGACTTGACCATGACGCTGGTTTGTCCAGCCCCATTTGGCACGCCGCGCTCAAGAGGT
CGGCTGCGCAGGAGGAAAGA

Downstream 100 bases:

>100_bases
GAGAGGGTTCGGTAAGTTGAGAATCGTTCTACTCGGACCGCCGGGTGCGGGCAAGGGCACGCAGGCGGCGAAGCTGGCCG
ACAAGCTGGGCGTCCCGCAC

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MLSAFISSLRTADLRRKILFTLGVVLLYRVGASLPSPGVNYPNVQECIAQVSGGESGQIYSLINLFSGGALLQLSVFAVG
VMPYITASIIVQLLTVVIPRFEQLRKEGQAGQSKMTQYTRYLAVALAVLQSTSIVALAANGGLLQGCALDIIEDQAIFSL
LVIVLVMTAGASLVMWMGELVTERGIGNGMSLIIFASIAAAMPGEGKSILDSRGGMVFAAVCAGALIIIIGVVFVEQGQR
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLVTQLIQSGSSNPGTGWWERFVAEYLTDPSSPWY
IGIYFALIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGKPTADYLRYVLSRITLPGSIYLGLIAVLPNLFANVGSS
GPVQNLPFGGVGVLIMIGVGLDTVKQIESQLMQRNYEGFLK

Sequences:

>Translated_441_residues
MLSAFISSLRTADLRRKILFTLGVVLLYRVGASLPSPGVNYPNVQECIAQVSGGESGQIYSLINLFSGGALLQLSVFAVG
VMPYITASIIVQLLTVVIPRFEQLRKEGQAGQSKMTQYTRYLAVALAVLQSTSIVALAANGGLLQGCALDIIEDQAIFSL
LVIVLVMTAGASLVMWMGELVTERGIGNGMSLIIFASIAAAMPGEGKSILDSRGGMVFAAVCAGALIIIIGVVFVEQGQR
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLVTQLIQSGSSNPGTGWWERFVAEYLTDPSSPWY
IGIYFALIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGKPTADYLRYVLSRITLPGSIYLGLIAVLPNLFANVGSS
GPVQNLPFGGVGVLIMIGVGLDTVKQIESQLMQRNYEGFLK
>Mature_441_residues
MLSAFISSLRTADLRRKILFTLGVVLLYRVGASLPSPGVNYPNVQECIAQVSGGESGQIYSLINLFSGGALLQLSVFAVG
VMPYITASIIVQLLTVVIPRFEQLRKEGQAGQSKMTQYTRYLAVALAVLQSTSIVALAANGGLLQGCALDIIEDQAIFSL
LVIVLVMTAGASLVMWMGELVTERGIGNGMSLIIFASIAAAMPGEGKSILDSRGGMVFAAVCAGALIIIIGVVFVEQGQR
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLVTQLIQSGSSNPGTGWWERFVAEYLTDPSSPWY
IGIYFALIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGKPTADYLRYVLSRITLPGSIYLGLIAVLPNLFANVGSS
GPVQNLPFGGVGVLIMIGVGLDTVKQIESQLMQRNYEGFLK

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=437, Percent_Identity=41.8764302059497, Blast_Score=294, Evalue=7e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47555; Mature: 47555

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAFISSLRTADLRRKILFTLGVVLLYRVGASLPSPGVNYPNVQECIAQVSGGESGQIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHH
SLINLFSGGALLQLSVFAVGVMPYITASIIVQLLTVVIPRFEQLRKEGQAGQSKMTQYTR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YLAVALAVLQSTSIVALAANGGLLQGCALDIIEDQAIFSLLVIVLVMTAGASLVMWMGEL
HHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VTERGIGNGMSLIIFASIAAAMPGEGKSILDSRGGMVFAAVCAGALIIIIGVVFVEQGQR
HHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLVTQLIQSGSSNPG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TGWWERFVAEYLTDPSSPWYIGIYFALIIFFTYFYVSITFNPDERADEMKKFGGFIPGIR
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCC
PGKPTADYLRYVLSRITLPGSIYLGLIAVLPNLFANVGSSGPVQNLPFGGVGVLIMIGVG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCC
LDTVKQIESQLMQRNYEGFLK
HHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MLSAFISSLRTADLRRKILFTLGVVLLYRVGASLPSPGVNYPNVQECIAQVSGGESGQIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHH
SLINLFSGGALLQLSVFAVGVMPYITASIIVQLLTVVIPRFEQLRKEGQAGQSKMTQYTR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YLAVALAVLQSTSIVALAANGGLLQGCALDIIEDQAIFSLLVIVLVMTAGASLVMWMGEL
HHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VTERGIGNGMSLIIFASIAAAMPGEGKSILDSRGGMVFAAVCAGALIIIIGVVFVEQGQR
HHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLVTQLIQSGSSNPG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TGWWERFVAEYLTDPSSPWYIGIYFALIIFFTYFYVSITFNPDERADEMKKFGGFIPGIR
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCC
PGKPTADYLRYVLSRITLPGSIYLGLIAVLPNLFANVGSSGPVQNLPFGGVGVLIMIGVG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCC
LDTVKQIESQLMQRNYEGFLK
HHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9350347; 12788972 [H]