BacMap

Definition	Mycobacterium sp. MCS chromosome, complete genome.
Accession	NC_008146
Length	5,705,448

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The map label for this gene is yxnA [H]

Identifier: 108797403

GI number: 108797403

Start: 468738

End: 469613

Strand: Direct

Name: yxnA [H]

Synonym: Mmcs_0423

Alternate gene names: 108797403

Gene position: 468738-469613 (Clockwise)

Preceding gene: 108797402

Following gene: 108797407

Centisome position: 8.22

GC content: 67.81

Gene sequence:

>876_bases
ATGGATGAATCTGCGGCAACACCCGAAGTGGTCGTGGTGACGGGTGCCTCCAGCGGCATCGGCGAGGAGACGGCCCTTCG
CTATGCGGGGCGCGGGGCGCGGCTGGTGCTCGCGGCACGCACCGAGGACGCGTTGCAGCGGGTCGCAGATGCCTGCCGCG
CGGCGGGCGCAGAGGCCGTACTGGTCCAGGCCACCGATATCGCCGACGCCGCCGAGGTCGAGGAACTGTTCGGCGTCGCC
GAGGGCCACTTCGGCCGGATCGACATCGTGGTGCAGTCGGCCGCGATCACCGCGTTCGGCCGGTTCGAGGACGTACCTGC
AGGCGTCTTCGACAGCATCGTGCGGACGAACCTCATCGGATCGGCGAACGTGGCGAGGTCGGCCCTCGCCCACTTCCACA
AGCGCGGCAGAGGGCATCTGGTACTGATCGGCTCCCTGCTCGGTACGGCCGCTGCGCCATACCAATCCGCCTACGTGGCA
AGTAAATTCGCGCTCAACGGGTTGGTGAGGACGTTGCGGCAGGAGAATCGCCACCTATCCGGCATCAAGATCCACGGTGT
CTACCCGGGTCCGGTCGACACCCCGGTCTACGGCACCGCGAGCAACTACTTCGGCCGCGCACCGCGGGTCCCGCCCACCG
CGGTCAAGCCGTCGTCCGTGGTTTCGGCGATCGTCCGCGCCACCGATCGCGGGCGTTCCAGTGAGCGCCAGGTGGGTGTG
TTCAACCGGCCCGTCATCGCGATGTACCGCCTGGCGCCGCCGGTGTACGACGTCCTCATGGGGGTGTTTCTGCGGACCTT
CGGCTTCACGTCCGAGTCGACGGAGCCGACCCACGGCAACGCTTTCGCGCGGGATCGTCATCCGAAAGCGGATTGA

Upstream 100 bases:

>100_bases
CGCCTTGCAGGTGCTCCGCATGTCCGAACGCAATCAACGAAAAGCGAAACTCGTTAGCAACGCCGAGGTTCCGGCAGGCT
CCCGGGGGTAATGCCCCACG

Downstream 100 bases:

>100_bases
GCGGAGCCTGGTTACGGGGCATCCGTCGTCGACAGCGGTTGGCGTTCGACGGAGCGCCCCAGGACGACCTTCGCCGTGAT
GACGCCCAACTTGACCATGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MDESAATPEVVVVTGASSGIGEETALRYAGRGARLVLAARTEDALQRVADACRAAGAEAVLVQATDIADAAEVEELFGVA
EGHFGRIDIVVQSAAITAFGRFEDVPAGVFDSIVRTNLIGSANVARSALAHFHKRGRGHLVLIGSLLGTAAAPYQSAYVA
SKFALNGLVRTLRQENRHLSGIKIHGVYPGPVDTPVYGTASNYFGRAPRVPPTAVKPSSVVSAIVRATDRGRSSERQVGV
FNRPVIAMYRLAPPVYDVLMGVFLRTFGFTSESTEPTHGNAFARDRHPKAD

Sequences:

>Translated_291_residues
MDESAATPEVVVVTGASSGIGEETALRYAGRGARLVLAARTEDALQRVADACRAAGAEAVLVQATDIADAAEVEELFGVA
EGHFGRIDIVVQSAAITAFGRFEDVPAGVFDSIVRTNLIGSANVARSALAHFHKRGRGHLVLIGSLLGTAAAPYQSAYVA
SKFALNGLVRTLRQENRHLSGIKIHGVYPGPVDTPVYGTASNYFGRAPRVPPTAVKPSSVVSAIVRATDRGRSSERQVGV
FNRPVIAMYRLAPPVYDVLMGVFLRTFGFTSESTEPTHGNAFARDRHPKAD
>Mature_291_residues
MDESAATPEVVVVTGASSGIGEETALRYAGRGARLVLAARTEDALQRVADACRAAGAEAVLVQATDIADAAEVEELFGVA
EGHFGRIDIVVQSAAITAFGRFEDVPAGVFDSIVRTNLIGSANVARSALAHFHKRGRGHLVLIGSLLGTAAAPYQSAYVA
SKFALNGLVRTLRQENRHLSGIKIHGVYPGPVDTPVYGTASNYFGRAPRVPPTAVKPSSVVSAIVRATDRGRSSERQVGV
FNRPVIAMYRLAPPVYDVLMGVFLRTFGFTSESTEPTHGNAFARDRHPKAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=34.5177664974619, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI4503817, Length=229, Percent_Identity=29.6943231441048, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI20149619, Length=190, Percent_Identity=32.1052631578947, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI38348362, Length=172, Percent_Identity=33.1395348837209, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38424085, Length=172, Percent_Identity=33.1395348837209, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI32455239, Length=166, Percent_Identity=33.7349397590361, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5031765, Length=166, Percent_Identity=33.7349397590361, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7657478, Length=197, Percent_Identity=27.9187817258883, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI157739938, Length=183, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI142976729, Length=216, Percent_Identity=26.3888888888889, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI210032110, Length=232, Percent_Identity=26.2931034482759, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4504505, Length=189, Percent_Identity=32.8042328042328, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=31.7460317460317, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI40807363, Length=264, Percent_Identity=25.7575757575758, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI223718074, Length=171, Percent_Identity=29.8245614035088, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40254992, Length=188, Percent_Identity=31.3829787234043, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI310128830, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI310115468, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI126723191, Length=172, Percent_Identity=32.5581395348837, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=191, Percent_Identity=32.9842931937173, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787335, Length=188, Percent_Identity=29.7872340425532, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786701, Length=186, Percent_Identity=28.494623655914, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787820, Length=190, Percent_Identity=26.8421052631579, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082160, Length=196, Percent_Identity=24.4897959183673, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787526, Length=194, Percent_Identity=25.2577319587629, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=214, Percent_Identity=27.5700934579439, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=191, Percent_Identity=29.8429319371728, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=171, Percent_Identity=29.8245614035088, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=214, Percent_Identity=27.5700934579439, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17570069, Length=177, Percent_Identity=27.683615819209, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=193, Percent_Identity=31.0880829015544, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=246, Percent_Identity=30.0813008130081, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=209, Percent_Identity=29.1866028708134, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=245, Percent_Identity=28.1632653061224, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=211, Percent_Identity=30.3317535545024, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=226, Percent_Identity=26.5486725663717, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=226, Percent_Identity=26.5486725663717, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=249, Percent_Identity=30.1204819277108, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=220, Percent_Identity=30.9090909090909, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=189, Percent_Identity=26.984126984127, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=203, Percent_Identity=26.1083743842365, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=242, Percent_Identity=26.8595041322314, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=189, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=32.2916666666667, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=29.1005291005291, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=180, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24580925, Length=198, Percent_Identity=31.3131313131313, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24648944, Length=208, Percent_Identity=29.8076923076923, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=31.9587628865979, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21358495, Length=261, Percent_Identity=26.4367816091954, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=27.8350515463918, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571387, Length=195, Percent_Identity=31.2820512820513, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644339, Length=189, Percent_Identity=29.1005291005291, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI23397609, Length=191, Percent_Identity=32.4607329842932, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364494, Length=206, Percent_Identity=27.1844660194175, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641232, Length=196, Percent_Identity=32.1428571428571, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24663911, Length=199, Percent_Identity=28.643216080402, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI116007238, Length=176, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641388, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356301, Length=229, Percent_Identity=25.764192139738, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355631, Length=177, Percent_Identity=24.2937853107345, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581726, Length=221, Percent_Identity=25.7918552036199, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648693, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355889, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364892, Length=171, Percent_Identity=28.0701754385965, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357673, Length=188, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI18859837, Length=175, Percent_Identity=32.5714285714286, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30810; Mature: 30810

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDESAATPEVVVVTGASSGIGEETALRYAGRGARLVLAARTEDALQRVADACRAAGAEAV
CCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEE
LVQATDIADAAEVEELFGVAEGHFGRIDIVVQSAAITAFGRFEDVPAGVFDSIVRTNLIG
EEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHCCC
SANVARSALAHFHKRGRGHLVLIGSLLGTAAAPYQSAYVASKFALNGLVRTLRQENRHLS
CHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GIKIHGVYPGPVDTPVYGTASNYFGRAPRVPPTAVKPSSVVSAIVRATDRGRSSERQVGV
CEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
FNRPVIAMYRLAPPVYDVLMGVFLRTFGFTSESTEPTHGNAFARDRHPKAD
CCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDESAATPEVVVVTGASSGIGEETALRYAGRGARLVLAARTEDALQRVADACRAAGAEAV
CCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEE
LVQATDIADAAEVEELFGVAEGHFGRIDIVVQSAAITAFGRFEDVPAGVFDSIVRTNLIG
EEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHCCC
SANVARSALAHFHKRGRGHLVLIGSLLGTAAAPYQSAYVASKFALNGLVRTLRQENRHLS
CHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GIKIHGVYPGPVDTPVYGTASNYFGRAPRVPPTAVKPSSVVSAIVRATDRGRSSERQVGV
CEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
FNRPVIAMYRLAPPVYDVLMGVFLRTFGFTSESTEPTHGNAFARDRHPKAD
CCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]