Definition Mycobacterium sp. MCS chromosome, complete genome.
Accession NC_008146
Length 5,705,448

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The map label for this gene is fabG [H]

Identifier: 108797272

GI number: 108797272

Start: 329604

End: 330401

Strand: Reverse

Name: fabG [H]

Synonym: Mmcs_0292

Alternate gene names: 108797272

Gene position: 330401-329604 (Counterclockwise)

Preceding gene: 108797273

Following gene: 108797267

Centisome position: 5.79

GC content: 68.42

Gene sequence:

>798_bases
ATGTCCCGTTACACCGATCGGCGCGTCCTCATCACCGGCGGCGGATCGGGCATCGGACAGGCGTGCGTGCTGCGGATCCT
CGACGAGGGCGGGCATGTCGTCGCCGCCGACGTCAGCGAAGCCGGACTGAAAGACACCGTGAGCAAGGCGCAGTCCGCCG
CCGACCGGCTGTCGACGCTCGTCATGGACGTCGGCGACGAGGAGTCGGTGAGGGCCGGGGTGGCCGAGGCGATCGGCATC
CTCGGCGGGCTGGACACCCTCGTCAACGTCGCGGGGATACTGCGCTCGGCGCGGCTCGAACAGACCACGCTGACCGACTT
CGAGCGGGTGTTGCGGATCAACCTGGTCGGCACGTTCCTGGTCACGCGGGAGGCGATTTCCGCGCTGCGCAACGGGAACG
GCCCCGCCGTGGTCAACTTCAGCTCGACGTCGGCGCATTTCGGCCATCCGTACATGTCGGCCTACGCCGCCTCCAAGGGC
GGCATCCTGTCGATGACCCACACCTTGGCGCTCGAGTTCGCAAAAGACGGCATCCGCTTCAATTGCGTTCAGCCGGGGTC
GATCTCGTCTGGTATGACCGATGGCACCGGTCAGGCCAGACAGAGCGTGGGTCCGGGCCTGCCCGACGACGCCGACTACT
CGCTGTTCTCGCGGCTGCAGCCGATGCTGGCCATCGACGGCGGCGCGATGTTCGCCGACCCGTCGGCCGTCGCCTCGGTG
GTGGCGATGCTCGGGTCGGCCGACGCGTTCTTCGTCACCGGCACCGAGGTGCGGGTCGACGGCGGCACCCACATGTGA

Upstream 100 bases:

>100_bases
ACCTATCCTGGCGCCGGGGCGACGATCGCCCAGGGCCTGGTGTACGGCTACATCGCCGCACAGGATGCGGCACAGGCCTG
ACTGAGAGGAGCTCACCGGA

Downstream 100 bases:

>100_bases
CCGGAGACGGTCAGAGGTCCTCGGCGACGGCGCGCAGCGCCTCGAGCTGATCGCAATAGTGACCGGCGGAGGTCGCCGCG
AGTGTGCACGTGACCGCCGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSRYTDRRVLITGGGSGIGQACVLRILDEGGHVVAADVSEAGLKDTVSKAQSAADRLSTLVMDVGDEESVRAGVAEAIGI
LGGLDTLVNVAGILRSARLEQTTLTDFERVLRINLVGTFLVTREAISALRNGNGPAVVNFSSTSAHFGHPYMSAYAASKG
GILSMTHTLALEFAKDGIRFNCVQPGSISSGMTDGTGQARQSVGPGLPDDADYSLFSRLQPMLAIDGGAMFADPSAVASV
VAMLGSADAFFVTGTEVRVDGGTHM

Sequences:

>Translated_265_residues
MSRYTDRRVLITGGGSGIGQACVLRILDEGGHVVAADVSEAGLKDTVSKAQSAADRLSTLVMDVGDEESVRAGVAEAIGI
LGGLDTLVNVAGILRSARLEQTTLTDFERVLRINLVGTFLVTREAISALRNGNGPAVVNFSSTSAHFGHPYMSAYAASKG
GILSMTHTLALEFAKDGIRFNCVQPGSISSGMTDGTGQARQSVGPGLPDDADYSLFSRLQPMLAIDGGAMFADPSAVASV
VAMLGSADAFFVTGTEVRVDGGTHM
>Mature_264_residues
SRYTDRRVLITGGGSGIGQACVLRILDEGGHVVAADVSEAGLKDTVSKAQSAADRLSTLVMDVGDEESVRAGVAEAIGIL
GGLDTLVNVAGILRSARLEQTTLTDFERVLRINLVGTFLVTREAISALRNGNGPAVVNFSSTSAHFGHPYMSAYAASKGG
ILSMTHTLALEFAKDGIRFNCVQPGSISSGMTDGTGQARQSVGPGLPDDADYSLFSRLQPMLAIDGGAMFADPSAVASVV
AMLGSADAFFVTGTEVRVDGGTHM

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=33.9622641509434, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=31.9230769230769, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI59889578, Length=241, Percent_Identity=31.1203319502075, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=28.1853281853282, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI4758504, Length=268, Percent_Identity=29.1044776119403, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI142976729, Length=239, Percent_Identity=25.1046025104602, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=31.6062176165803, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=29.0697674418605, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=32.620320855615, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI83715985, Length=181, Percent_Identity=33.1491712707182, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI66933014, Length=266, Percent_Identity=25.187969924812, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=29.1828793774319, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI10190704, Length=263, Percent_Identity=29.277566539924, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI40254992, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI19743808, Length=200, Percent_Identity=33, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=24.7368421052632, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4504503, Length=225, Percent_Identity=27.5555555555556, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=29.8342541436464, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI126723750, Length=265, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI40548397, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI214010158, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI214010156, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI22758144, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI22507405, Length=194, Percent_Identity=30.4123711340206, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI150247226, Length=200, Percent_Identity=33.5, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4503817, Length=182, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI109715829, Length=198, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI40254986, Length=225, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680136, Length=207, Percent_Identity=27.536231884058, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI44680133, Length=207, Percent_Identity=27.536231884058, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI17738292, Length=207, Percent_Identity=27.536231884058, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1789378, Length=266, Percent_Identity=30.8270676691729, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=29.9242424242424, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI2367175, Length=261, Percent_Identity=34.8659003831418, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082100, Length=268, Percent_Identity=29.4776119402985, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=29.0196078431373, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=27.3076923076923, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=24.8031496062992, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=24.21875, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367365, Length=263, Percent_Identity=29.6577946768061, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789057, Length=267, Percent_Identity=26.5917602996255, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082160, Length=192, Percent_Identity=23.9583333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=24.2307692307692, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=261, Percent_Identity=31.4176245210728, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=191, Percent_Identity=35.6020942408377, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=271, Percent_Identity=30.2583025830258, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=29.3436293436293, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982365, Length=232, Percent_Identity=28.8793103448276, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=278, Percent_Identity=27.3381294964029, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=27.2373540856031, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=279, Percent_Identity=25.4480286738351, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=274, Percent_Identity=25.1824817518248, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=277, Percent_Identity=27.0758122743682, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=25.8181818181818, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=242, Percent_Identity=25.6198347107438, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=282, Percent_Identity=25.177304964539, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=275, Percent_Identity=24.7272727272727, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=262, Percent_Identity=30.1526717557252, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=275, Percent_Identity=25.8181818181818, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=28.2722513089005, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=274, Percent_Identity=24.0875912408759, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=277, Percent_Identity=27.4368231046931, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=278, Percent_Identity=27.3381294964029, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=279, Percent_Identity=24.7311827956989, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=22.3484848484848, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=203, Percent_Identity=25.615763546798, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=203, Percent_Identity=25.615763546798, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=28.4090909090909, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=276, Percent_Identity=25, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=275, Percent_Identity=24.7272727272727, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=266, Percent_Identity=25.187969924812, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=24.5421245421245, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=22.992700729927, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17558628, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=201, Percent_Identity=26.865671641791, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=201, Percent_Identity=26.865671641791, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=278, Percent_Identity=24.1007194244604, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=27.6515151515151, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=246, Percent_Identity=26.0162601626016, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=33.5907335907336, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571526, Length=269, Percent_Identity=31.5985130111524, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24644339, Length=265, Percent_Identity=31.6981132075472, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357041, Length=269, Percent_Identity=30.8550185873606, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI23397609, Length=264, Percent_Identity=31.0606060606061, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357673, Length=226, Percent_Identity=28.3185840707965, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737361, Length=196, Percent_Identity=32.1428571428571, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI18859837, Length=233, Percent_Identity=31.7596566523605, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24643142, Length=264, Percent_Identity=28.4090909090909, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24644337, Length=184, Percent_Identity=31.5217391304348, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648693, Length=217, Percent_Identity=30.4147465437788, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355889, Length=217, Percent_Identity=30.4147465437788, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355319, Length=269, Percent_Identity=23.0483271375465, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641388, Length=222, Percent_Identity=30.1801801801802, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221331218, Length=226, Percent_Identity=29.2035398230088, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665243, Length=226, Percent_Identity=29.2035398230088, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331216, Length=226, Percent_Identity=29.2035398230088, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24665247, Length=226, Percent_Identity=29.2035398230088, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007234, Length=204, Percent_Identity=29.9019607843137, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281364494, Length=205, Percent_Identity=27.8048780487805, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21356301, Length=240, Percent_Identity=22.5, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24649181, Length=218, Percent_Identity=27.5229357798165, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27399; Mature: 27268

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSRYTDRRVLITGGGSGIGQACVLRILDEGGHVVAADVSEAGLKDTVSKAQSAADRLSTL
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHH
VMDVGDEESVRAGVAEAIGILGGLDTLVNVAGILRSARLEQTTLTDFERVLRINLVGTFL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTREAISALRNGNGPAVVNFSSTSAHFGHPYMSAYAASKGGILSMTHTLALEFAKDGIRF
HHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHCCCEE
NCVQPGSISSGMTDGTGQARQSVGPGLPDDADYSLFSRLQPMLAIDGGAMFADPSAVASV
EEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHCCHHEEECCCCEEECHHHHHHH
VAMLGSADAFFVTGTEVRVDGGTHM
HHHHCCCCEEEEECCEEEECCCCCC
>Mature Secondary Structure 
SRYTDRRVLITGGGSGIGQACVLRILDEGGHVVAADVSEAGLKDTVSKAQSAADRLSTL
CCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHH
VMDVGDEESVRAGVAEAIGILGGLDTLVNVAGILRSARLEQTTLTDFERVLRINLVGTFL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTREAISALRNGNGPAVVNFSSTSAHFGHPYMSAYAASKGGILSMTHTLALEFAKDGIRF
HHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHCCCEE
NCVQPGSISSGMTDGTGQARQSVGPGLPDDADYSLFSRLQPMLAIDGGAMFADPSAVASV
EEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHCCHHEEECCCCEEECHHHHHHH
VAMLGSADAFFVTGTEVRVDGGTHM
HHHHCCCCEEEEECCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]