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The map label for this gene is pckG [H]

Identifier: 108797156

GI number: 108797156

Start: 194404

End: 196233

Strand: Direct

Name: pckG [H]

Synonym: Mmcs_0176

Alternate gene names: 108797156

Gene position: 194404-196233 (Clockwise)

Preceding gene: 108797155

Following gene: 108797157

Centisome position: 3.41

GC content: 66.56

Gene sequence:

>1830_bases
ATGACTTCAGCCACCATTCCGGGTCTGGACACCGCTCCGACCGAACACGAGGGACTGCTGGCCTGGGTTCGGGAGGTCGC
CGAGCTGACCCAGCCCGACCGGGTGGTGTTCACCGACGGTTCCGAGGAGGAGTGCGCCCGGCTGACCGAGCAGCTGTGCG
AGGCGGGCACCTTCCAGAAGCTGAACGAGGAGAAGAAGCCGAACTCATACCTGGCACTCTCCGACCCCTCCGACGTGGCG
CGCGTCGAGTCGCGCACCTATATCTGCTCTGAGCGTGAGATCGACGCCGGTCCGACCAACAACTGGATGGACCCCGCGGA
GATGCGCGGCATCATGACCGACCTGTACCGCGGCAGCATGCGTGGCCGCACCATGTATGTGGTGCCGTTCTGCATGGGTC
CGCTCGAAGCCGAGGACCCCAAGCTCGGCGTGGAGATCACCGATTCGGAGTACGTGGTGGTCTCGATGCGCACGATGACC
CGCATGGGTCAGGCGGCCCTCGACAAGATGGGCACCGACGGGTTCTTCGTCAAGGCGCTGCACTCCCTCGGTGCGCCGCT
GGAGCCCGGTGAGAAGGACGTGCCGTGGCCGTGCAACGACACCAAGTACATCACCCACTTCCCCGAGACCCGCGAGATCT
GGAGCTACGGATCGGGTTACGGCGGCAACGCGCTGCTCGGCAAGAAGTGCTACTCGCTTCGGATCGCCTCGGCGATGGCC
CATGACGAGGGCTGGCTCGCCGAGCACATGCTGATCCTCAAGCTCATCTCCCCGGAGAACAAGGCCTACTTCATCGCTGC
GGCGTTCCCGTCGGCCTGCGGGAAGACCAACCTCGCGATGCTGCAGCCCACCATCCCGGGCTGGCGCGCCGAGACCGTCG
GCGACGACATCGCGTGGATGCGGTTCGGCAAGGACGGGCGCCTGTACGCCGTCAACCCCGAATTCGGCTTCTTCGGCGTC
GCCCCCGGCACGAACTGGTCGTCGAACCCGAACGCGATGAAGACCATCGAGGCCGGCAACACCGTCTTCACCAACGTCGC
CAAGACCGACGACGGCGATGTGTGGTGGGAAGGTCTGGAGGGTGAGCCCGACCACCTGATCGACTGGAAGGGCAACGACT
ACATCCTGCGTGAGACGGAAACGAAGGCCGCCCACCCGAACTCGCGTTACTGCACGCCGATCTCCCAGTGCCCGACGCTG
GCGCCCGAGTGGGATGATCCGCAGGGCGTGCCGATCTCGGCCATCCTGTTCGGCGGCCGCCGCAAGACGACCGTCCCGCT
GATCACCCAGGCCCGCGACTGGCAGCACGGCGTCTTCATCGGCGCCACCCTCGGCTCGGAGCAGACCGCCGCCGCCGAGG
GCAAGGTCGGCACGGTGCGTCGCGATCCGATGGCGATGCTGCCGTTCCTCGGCTACAACGTCGGCGACTACTTCCAGCAC
TGGATCGACATCGGCAAGAACGCCGACGAGTCGAAGATGCCCGCGGTGTTCTTCGTGAACTGGTTCCGCCGCGGCGACGA
CGGCCGCTTCCTGTGGCCGGGCTTCGGCGAGAACAGCCGCGTGCTCAAGTGGGCGATCGAGCGCATCGAGCACAAGGCCG
ACGGCCGCAGCACGCCGATCGGCATCGTGCCGACCGCGCAGGACCTCGACCTCGAGGGTCTGGATGTCGACCCGGAGGAC
GTCGACGCCGCGCTGGCGGTCAAGCCCGAGGAGTGGCGGCAGGAACTGCCGCTCATCGAGGAGTGGTTCGAGTTCGTCGG
CGAGAAGCTGCCCACGGGCATCCGCGACGAGTTCGACGCGCTCAAGCACCGTCTGGCCGAAGAGGCTTAA

Upstream 100 bases:

>100_bases
CAAGGGACGACCGTGATCGCCGTTGATCTCGTTCATCGGCGTCATCGTGGGCCTGCGTCCTGGCGGAACCTAGTGCAGGA
AGATGCAGGAGAATCACAGT

Downstream 100 bases:

>100_bases
TTCTCTTTCACCGCGAGCGGCGTGTCTGATCTTCGACACGCCGCTCGCGGTGCGCTTTTGACGCCCGCTCTCGGCCGCGC
GACGGTGTGCTCCCGGCCAT

Product: phosphoenolpyruvate carboxykinase

Products: NA

Alternate protein names: PEP carboxykinase; PEPCK; Phosphoenolpyruvate carboxylase [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MTSATIPGLDTAPTEHEGLLAWVREVAELTQPDRVVFTDGSEEECARLTEQLCEAGTFQKLNEEKKPNSYLALSDPSDVA
RVESRTYICSEREIDAGPTNNWMDPAEMRGIMTDLYRGSMRGRTMYVVPFCMGPLEAEDPKLGVEITDSEYVVVSMRTMT
RMGQAALDKMGTDGFFVKALHSLGAPLEPGEKDVPWPCNDTKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMA
HDEGWLAEHMLILKLISPENKAYFIAAAFPSACGKTNLAMLQPTIPGWRAETVGDDIAWMRFGKDGRLYAVNPEFGFFGV
APGTNWSSNPNAMKTIEAGNTVFTNVAKTDDGDVWWEGLEGEPDHLIDWKGNDYILRETETKAAHPNSRYCTPISQCPTL
APEWDDPQGVPISAILFGGRRKTTVPLITQARDWQHGVFIGATLGSEQTAAAEGKVGTVRRDPMAMLPFLGYNVGDYFQH
WIDIGKNADESKMPAVFFVNWFRRGDDGRFLWPGFGENSRVLKWAIERIEHKADGRSTPIGIVPTAQDLDLEGLDVDPED
VDAALAVKPEEWRQELPLIEEWFEFVGEKLPTGIRDEFDALKHRLAEEA

Sequences:

>Translated_609_residues
MTSATIPGLDTAPTEHEGLLAWVREVAELTQPDRVVFTDGSEEECARLTEQLCEAGTFQKLNEEKKPNSYLALSDPSDVA
RVESRTYICSEREIDAGPTNNWMDPAEMRGIMTDLYRGSMRGRTMYVVPFCMGPLEAEDPKLGVEITDSEYVVVSMRTMT
RMGQAALDKMGTDGFFVKALHSLGAPLEPGEKDVPWPCNDTKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMA
HDEGWLAEHMLILKLISPENKAYFIAAAFPSACGKTNLAMLQPTIPGWRAETVGDDIAWMRFGKDGRLYAVNPEFGFFGV
APGTNWSSNPNAMKTIEAGNTVFTNVAKTDDGDVWWEGLEGEPDHLIDWKGNDYILRETETKAAHPNSRYCTPISQCPTL
APEWDDPQGVPISAILFGGRRKTTVPLITQARDWQHGVFIGATLGSEQTAAAEGKVGTVRRDPMAMLPFLGYNVGDYFQH
WIDIGKNADESKMPAVFFVNWFRRGDDGRFLWPGFGENSRVLKWAIERIEHKADGRSTPIGIVPTAQDLDLEGLDVDPED
VDAALAVKPEEWRQELPLIEEWFEFVGEKLPTGIRDEFDALKHRLAEEA
>Mature_608_residues
TSATIPGLDTAPTEHEGLLAWVREVAELTQPDRVVFTDGSEEECARLTEQLCEAGTFQKLNEEKKPNSYLALSDPSDVAR
VESRTYICSEREIDAGPTNNWMDPAEMRGIMTDLYRGSMRGRTMYVVPFCMGPLEAEDPKLGVEITDSEYVVVSMRTMTR
MGQAALDKMGTDGFFVKALHSLGAPLEPGEKDVPWPCNDTKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMAH
DEGWLAEHMLILKLISPENKAYFIAAAFPSACGKTNLAMLQPTIPGWRAETVGDDIAWMRFGKDGRLYAVNPEFGFFGVA
PGTNWSSNPNAMKTIEAGNTVFTNVAKTDDGDVWWEGLEGEPDHLIDWKGNDYILRETETKAAHPNSRYCTPISQCPTLA
PEWDDPQGVPISAILFGGRRKTTVPLITQARDWQHGVFIGATLGSEQTAAAEGKVGTVRRDPMAMLPFLGYNVGDYFQHW
IDIGKNADESKMPAVFFVNWFRRGDDGRFLWPGFGENSRVLKWAIERIEHKADGRSTPIGIVPTAQDLDLEGLDVDPEDV
DAALAVKPEEWRQELPLIEEWFEFVGEKLPTGIRDEFDALKHRLAEEA

Specific function: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle [H]

COG id: COG1274

COG function: function code C; Phosphoenolpyruvate carboxykinase (GTP)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family [H]

Homologues:

Organism=Homo sapiens, GI187281517, Length=615, Percent_Identity=49.9186991869919, Blast_Score=591, Evalue=1e-169,
Organism=Homo sapiens, GI66346721, Length=604, Percent_Identity=49.8344370860927, Blast_Score=574, Evalue=1e-164,
Organism=Homo sapiens, GI66346723, Length=354, Percent_Identity=54.2372881355932, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71989645, Length=601, Percent_Identity=48.585690515807, Blast_Score=566, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71989658, Length=601, Percent_Identity=48.585690515807, Blast_Score=565, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71989653, Length=592, Percent_Identity=48.6486486486487, Blast_Score=558, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI17555492, Length=612, Percent_Identity=47.2222222222222, Blast_Score=541, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI32564411, Length=532, Percent_Identity=50.187969924812, Blast_Score=521, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI32564407, Length=524, Percent_Identity=49.8091603053435, Blast_Score=500, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI71989649, Length=478, Percent_Identity=50.836820083682, Blast_Score=483, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI32564409, Length=370, Percent_Identity=48.6486486486487, Blast_Score=344, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17540956, Length=502, Percent_Identity=26.0956175298805, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24655085, Length=602, Percent_Identity=50.3322259136213, Blast_Score=586, Evalue=1e-167,
Organism=Drosophila melanogaster, GI24655082, Length=601, Percent_Identity=49.5840266222962, Blast_Score=572, Evalue=1e-163,
Organism=Drosophila melanogaster, GI161077226, Length=558, Percent_Identity=50.7168458781362, Blast_Score=551, Evalue=1e-157,
Organism=Drosophila melanogaster, GI24655088, Length=503, Percent_Identity=51.4910536779324, Blast_Score=515, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018091
- InterPro:   IPR013035
- InterPro:   IPR008209
- InterPro:   IPR008210 [H]

Pfam domain/function: PF00821 PEPCK [H]

EC number: =4.1.1.32 [H]

Molecular weight: Translated: 67822; Mature: 67691

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00505 PEPCK_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSATIPGLDTAPTEHEGLLAWVREVAELTQPDRVVFTDGSEEECARLTEQLCEAGTFQK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCHHH
LNEEKKPNSYLALSDPSDVARVESRTYICSEREIDAGPTNNWMDPAEMRGIMTDLYRGSM
HHHCCCCCCEEEECCCHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
RGRTMYVVPFCMGPLEAEDPKLGVEITDSEYVVVSMRTMTRMGQAALDKMGTDGFFVKAL
CCCEEEEEEEECCCCCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHH
HSLGAPLEPGEKDVPWPCNDTKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMA
HHCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
HDEGWLAEHMLILKLISPENKAYFIAAAFPSACGKTNLAMLQPTIPGWRAETVGDDIAWM
CCCCHHHHHHHHHHEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEEE
RFGKDGRLYAVNPEFGFFGVAPGTNWSSNPNAMKTIEAGNTVFTNVAKTDDGDVWWEGLE
EECCCCCEEEECCCCCEEECCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCEEEECCC
GEPDHLIDWKGNDYILRETETKAAHPNSRYCTPISQCPTLAPEWDDPQGVPISAILFGGR
CCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEECCC
RKTTVPLITQARDWQHGVFIGATLGSEQTAAAEGKVGTVRRDPMAMLPFLGYNVGDYFQH
CCCCCEEEECCCCCCCCEEEEEECCCCCHHCCCCCCCCEECCCHHHHHHHCCCHHHHHHH
WIDIGKNADESKMPAVFFVNWFRRGDDGRFLWPGFGENSRVLKWAIERIEHKADGRSTPI
HHHHCCCCCCHHCCEEEEEEEHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCE
GIVPTAQDLDLEGLDVDPEDVDAALAVKPEEWRQELPLIEEWFEFVGEKLPTGIRDEFDA
EEECCCCCCCCCCCCCCHHHCCEEEEECCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
LKHRLAEEA
HHHHHHHCC
>Mature Secondary Structure 
TSATIPGLDTAPTEHEGLLAWVREVAELTQPDRVVFTDGSEEECARLTEQLCEAGTFQK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCHHH
LNEEKKPNSYLALSDPSDVARVESRTYICSEREIDAGPTNNWMDPAEMRGIMTDLYRGSM
HHHCCCCCCEEEECCCHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
RGRTMYVVPFCMGPLEAEDPKLGVEITDSEYVVVSMRTMTRMGQAALDKMGTDGFFVKAL
CCCEEEEEEEECCCCCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHH
HSLGAPLEPGEKDVPWPCNDTKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMA
HHCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
HDEGWLAEHMLILKLISPENKAYFIAAAFPSACGKTNLAMLQPTIPGWRAETVGDDIAWM
CCCCHHHHHHHHHHEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEEE
RFGKDGRLYAVNPEFGFFGVAPGTNWSSNPNAMKTIEAGNTVFTNVAKTDDGDVWWEGLE
EECCCCCEEEECCCCCEEECCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCEEEECCC
GEPDHLIDWKGNDYILRETETKAAHPNSRYCTPISQCPTLAPEWDDPQGVPISAILFGGR
CCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEECCC
RKTTVPLITQARDWQHGVFIGATLGSEQTAAAEGKVGTVRRDPMAMLPFLGYNVGDYFQH
CCCCCEEEECCCCCCCCEEEEEECCCCCHHCCCCCCCCEECCCHHHHHHHCCCHHHHHHH
WIDIGKNADESKMPAVFFVNWFRRGDDGRFLWPGFGENSRVLKWAIERIEHKADGRSTPI
HHHHCCCCCCHHCCEEEEEEEHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCE
GIVPTAQDLDLEGLDVDPEDVDAALAVKPEEWRQELPLIEEWFEFVGEKLPTGIRDEFDA
EEECCCCCCCCCCCCCCHHHCCEEEEECCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
LKHRLAEEA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA