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The map label for this gene is dhbC [H]

Identifier: 108763046

GI number: 108763046

Start: 4348746

End: 4349990

Strand: Reverse

Name: dhbC [H]

Synonym: MXAN_3646

Alternate gene names: 108763046

Gene position: 4349990-4348746 (Counterclockwise)

Preceding gene: 108759915

Following gene: 108757791

Centisome position: 47.59

GC content: 71.73

Gene sequence:

>1245_bases
ATGACGCCCGCTGAGCCGAAGGAACAGGAACACCCCATGGGACCGCAGACACTCGCCGCGCAGTTGCTCGAGAGCTACGA
GGCTGGCTCTTCGTTCTTCTTCGCCACGCCGCGCCGCACGCTGCTGGCGCGCGGCACCTTTGCTACCGTGCCACACCAGG
GCGGCGCGGATGCCCTGGCGCGGCTCCCCGTGCGCGTGACGGCGGTGCTGAATGACGCGCGCCAGGCCGACCACGACATC
CCCGTGGCGGTGGGCGCGGTGCCCTTCGACGGCTCGGTACCCGCACAGCTCGTGGTGCCGCTGACGCTCCAGCGCGCCGG
GCCGCTGGTGTTCGACAAGGACGTCCCGGTGCAGCGGCCGTTCAGCGCCAGCTACACCGTCCAGCCGGTGCCGGAGCCCG
CCGCGTACCTGAACGGCGTCGCGCAGGCCCTGAAGCTGATGCAGAGCGGGCCGCTCCAGAAGGTGGTGCTGTCACGTTCG
CTGCACCTCAACGCCGCCGCCCCCATCGACCTGCGGCAGCTGCTGCGCAACCTCGCGCAGCGCAACCCGTCGGGCTACAC
CTTCGCCGCCGACCTCCCCCAGCAGGATGGGACCCGCGGCGCGGGACTTCGCACGCTCATTGGCGCCAGCCCCGAGCTGC
TCGTGTCCCGCTCCGGGTTCCAGGTGGTCGCCAATCCCCTGGCCGGCTCCGCGGCCCGCAGCGCGGATCCGCTGGAGGAC
CAGGAGCGCGCCGCCGCGCTGCTGAAGTCGCCCAAGGACCTGCACGAGCACGCGGTGGTCATCGACGCCGTCGCGGAGGC
GCTGCGGCCGTACTGCAAGACGCTGAACGTGCCCGCCGGTCCGTCGCTCGTGAACACCGCCACCATGTGGCACCTGTCCA
GCCGCATCACCGGTGAGCTGGCCGACCCCTCCATCTCCTCGCTGACGCTGGCGGCGGCCATGCACCCGACGCCGGCGGTG
TGCGGCTATCCTACACGGCTGGCGCACGAGGCGATTGGCTCCATCGAGCCCTTCGAGCGCGGCTACTACACCGGCACGGT
GGGCTGGTGCGACGCCACGGGTGATGGGCAGTGGGCGGTGACCATCCGTTGCGCGGAGGCCAGTGAGCGCACCCTGCGCA
TCTTCGCGGGCGCGGGCATCGTGGTGGGCTCCACGCCCGAGTCCGAGCTGGCGGAGACCGAGGCCAAGTTCCGCACCATG
CTCCACGCCATGGGCCTGGGCCACGGTGCCGGGGTGCAGTCATGA

Upstream 100 bases:

>100_bases
TGCGGCCCGCCCAGGCCCTCGTCCGCCACGGAGTTGATAATGATTACTAGGATCCAATTCACCAACTACCACCGAGGCGC
CGCCATGTGGCGCCCTGTGC

Downstream 100 bases:

>100_bases
CGTCCCCCGCCCTCCCTGGCTGCCCCACCTGGCCGGAGGCCTACGCCGCCCGCTACCGCGAGGCTGGCTACTGGCGCAGT
GAAACGTTCGGCCAGCTCCT

Product: isochorismate synthase DhbC

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MTPAEPKEQEHPMGPQTLAAQLLESYEAGSSFFFATPRRTLLARGTFATVPHQGGADALARLPVRVTAVLNDARQADHDI
PVAVGAVPFDGSVPAQLVVPLTLQRAGPLVFDKDVPVQRPFSASYTVQPVPEPAAYLNGVAQALKLMQSGPLQKVVLSRS
LHLNAAAPIDLRQLLRNLAQRNPSGYTFAADLPQQDGTRGAGLRTLIGASPELLVSRSGFQVVANPLAGSAARSADPLED
QERAAALLKSPKDLHEHAVVIDAVAEALRPYCKTLNVPAGPSLVNTATMWHLSSRITGELADPSISSLTLAAAMHPTPAV
CGYPTRLAHEAIGSIEPFERGYYTGTVGWCDATGDGQWAVTIRCAEASERTLRIFAGAGIVVGSTPESELAETEAKFRTM
LHAMGLGHGAGVQS

Sequences:

>Translated_414_residues
MTPAEPKEQEHPMGPQTLAAQLLESYEAGSSFFFATPRRTLLARGTFATVPHQGGADALARLPVRVTAVLNDARQADHDI
PVAVGAVPFDGSVPAQLVVPLTLQRAGPLVFDKDVPVQRPFSASYTVQPVPEPAAYLNGVAQALKLMQSGPLQKVVLSRS
LHLNAAAPIDLRQLLRNLAQRNPSGYTFAADLPQQDGTRGAGLRTLIGASPELLVSRSGFQVVANPLAGSAARSADPLED
QERAAALLKSPKDLHEHAVVIDAVAEALRPYCKTLNVPAGPSLVNTATMWHLSSRITGELADPSISSLTLAAAMHPTPAV
CGYPTRLAHEAIGSIEPFERGYYTGTVGWCDATGDGQWAVTIRCAEASERTLRIFAGAGIVVGSTPESELAETEAKFRTM
LHAMGLGHGAGVQS
>Mature_413_residues
TPAEPKEQEHPMGPQTLAAQLLESYEAGSSFFFATPRRTLLARGTFATVPHQGGADALARLPVRVTAVLNDARQADHDIP
VAVGAVPFDGSVPAQLVVPLTLQRAGPLVFDKDVPVQRPFSASYTVQPVPEPAAYLNGVAQALKLMQSGPLQKVVLSRSL
HLNAAAPIDLRQLLRNLAQRNPSGYTFAADLPQQDGTRGAGLRTLIGASPELLVSRSGFQVVANPLAGSAARSADPLEDQ
ERAAALLKSPKDLHEHAVVIDAVAEALRPYCKTLNVPAGPSLVNTATMWHLSSRITGELADPSISSLTLAAAMHPTPAVC
GYPTRLAHEAIGSIEPFERGYYTGTVGWCDATGDGQWAVTIRCAEASERTLRIFAGAGIVVGSTPESELAETEAKFRTML
HAMGLGHGAGVQS

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=386, Percent_Identity=39.3782383419689, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI87082077, Length=280, Percent_Identity=29.6428571428571, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787518, Length=283, Percent_Identity=30.3886925795053, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788114, Length=289, Percent_Identity=26.2975778546713, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320935, Length=309, Percent_Identity=28.4789644012945, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324361, Length=295, Percent_Identity=23.0508474576271, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 43672; Mature: 43541

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAEPKEQEHPMGPQTLAAQLLESYEAGSSFFFATPRRTLLARGTFATVPHQGGADALA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHEECCCEEECCCCCCHHHHH
RLPVRVTAVLNDARQADHDIPVAVGAVPFDGSVPAQLVVPLTLQRAGPLVFDKDVPVQRP
HCCCCEEEHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEHHCCCCEEEECCCCCCCC
FSASYTVQPVPEPAAYLNGVAQALKLMQSGPLQKVVLSRSLHLNAAAPIDLRQLLRNLAQ
CCCCEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RNPSGYTFAADLPQQDGTRGAGLRTLIGASPELLVSRSGFQVVANPLAGSAARSADPLED
CCCCCEEEEECCCCCCCCCCCCHHHHHCCCHHHEEECCCCEEEECCCCCCCCCCCCCCCH
QERAAALLKSPKDLHEHAVVIDAVAEALRPYCKTLNVPAGPSLVNTATMWHLSSRITGEL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
ADPSISSLTLAAAMHPTPAVCGYPTRLAHEAIGSIEPFERGYYTGTVGWCDATGDGQWAV
CCCCHHHEEEEHHCCCCCCCCCCHHHHHHHHHCCCCCHHCCEEECCEEEEECCCCCCEEE
TIRCAEASERTLRIFAGAGIVVGSTPESELAETEAKFRTMLHAMGLGHGAGVQS
EEEECCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TPAEPKEQEHPMGPQTLAAQLLESYEAGSSFFFATPRRTLLARGTFATVPHQGGADALA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHEECCCEEECCCCCCHHHHH
RLPVRVTAVLNDARQADHDIPVAVGAVPFDGSVPAQLVVPLTLQRAGPLVFDKDVPVQRP
HCCCCEEEHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEHHCCCCEEEECCCCCCCC
FSASYTVQPVPEPAAYLNGVAQALKLMQSGPLQKVVLSRSLHLNAAAPIDLRQLLRNLAQ
CCCCEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RNPSGYTFAADLPQQDGTRGAGLRTLIGASPELLVSRSGFQVVANPLAGSAARSADPLED
CCCCCEEEEECCCCCCCCCCCCHHHHHCCCHHHEEECCCCEEEECCCCCCCCCCCCCCCH
QERAAALLKSPKDLHEHAVVIDAVAEALRPYCKTLNVPAGPSLVNTATMWHLSSRITGEL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
ADPSISSLTLAAAMHPTPAVCGYPTRLAHEAIGSIEPFERGYYTGTVGWCDATGDGQWAV
CCCCHHHEEEEHHCCCCCCCCCCHHHHHHHHHCCCCCHHCCEEECCEEEEECCCCCCEEE
TIRCAEASERTLRIFAGAGIVVGSTPESELAETEAKFRTMLHAMGLGHGAGVQS
EEEECCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377 [H]