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The map label for this gene is tolQ [H]

Identifier: 108762277

GI number: 108762277

Start: 5852182

End: 5852904

Strand: Direct

Name: tolQ [H]

Synonym: MXAN_4669

Alternate gene names: 108762277

Gene position: 5852182-5852904 (Clockwise)

Preceding gene: 108759052

Following gene: 108759585

Centisome position: 64.03

GC content: 70.95

Gene sequence:

>723_bases
ATGAGCCTGAACGACATCCTCCATTACCTCCGCCTGGGTGGCGTCACCCTCGCCATGCTCATCTTCGCCTCGGTCGCGGC
GTTGATTGTCGCCGTCGAGCGCATCATCGTGCTCTGGGGCGTGGGCGAGCGTTCACGCGCCTTGGGTGAGACAGTGAACA
AACACCTGCTGCGCGGGGACGTCGCCGCGGCCCGCACCGCCGCCGAGCGCTCCGACGCGGTGGCCGCCGACATCTTCCTG
GCCGGGTTCGACCGGATGGAGCGCAGCCGCACCGCCGGGGGCGCTGGCATCGAGGCGGCGGTGGAACGCGAGCGCGCCCA
GGTGGCCCTCAAGCTGCGCCGCTACCTGTGGATCCTGGCCACCATCGGCTCGATTACGCCCTTCGTGGGCCTCTTCGGCA
CCGTCGCCGGCATCATGCGCTCCTTCAAGGACCTGGGCCTGGACGTGGAAGCGGGCGGCACCGGCGGCAGCTCGGCGGTG
ATGACGGGCATCTCCGAGGCCCTGGTCGCCACCGCGGTGGGCATCCTGGTCGCCGTGCAGGCGATGGTCTTCTACAACTA
CTTCCAGGCCCGCCTGTCCCGCGTGCTGGTGGAGCTGCGCCTGATTGGCGACGAGTTCGTCGAGCTGCTCAAGGAGCGGG
CCGCCGGCCTGCCGCCGTCCGAGCCCATGCCTCCCGAGCCGCAGGCCGCCCCCGCCACGCGCACGGACGCACAGCCCGCC
TAG

Upstream 100 bases:

>100_bases
CTTGGGACAGCCAGAACAGAGCACTACCAGGAAGATTGCGACGGCTGCGCGGTTCATATGGCCTAGTCTGGGCCAAGCCG
CCCTGCCCGGTCACCCACCA

Downstream 100 bases:

>100_bases
GCCGGAGGAGAACGCACCATGGGCATGGGAAAGACTCCGGGCAGCGACGACGGCTCCGAGGACGGCGTCTTCGCTGAAAT
CAACATCACCCCGCTCACCG

Product: MotA/TolQ/ExbB proton channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSLNDILHYLRLGGVTLAMLIFASVAALIVAVERIIVLWGVGERSRALGETVNKHLLRGDVAAARTAAERSDAVAADIFL
AGFDRMERSRTAGGAGIEAAVERERAQVALKLRRYLWILATIGSITPFVGLFGTVAGIMRSFKDLGLDVEAGGTGGSSAV
MTGISEALVATAVGILVAVQAMVFYNYFQARLSRVLVELRLIGDEFVELLKERAAGLPPSEPMPPEPQAAPATRTDAQPA

Sequences:

>Translated_240_residues
MSLNDILHYLRLGGVTLAMLIFASVAALIVAVERIIVLWGVGERSRALGETVNKHLLRGDVAAARTAAERSDAVAADIFL
AGFDRMERSRTAGGAGIEAAVERERAQVALKLRRYLWILATIGSITPFVGLFGTVAGIMRSFKDLGLDVEAGGTGGSSAV
MTGISEALVATAVGILVAVQAMVFYNYFQARLSRVLVELRLIGDEFVELLKERAAGLPPSEPMPPEPQAAPATRTDAQPA
>Mature_239_residues
SLNDILHYLRLGGVTLAMLIFASVAALIVAVERIIVLWGVGERSRALGETVNKHLLRGDVAAARTAAERSDAVAADIFLA
GFDRMERSRTAGGAGIEAAVERERAQVALKLRRYLWILATIGSITPFVGLFGTVAGIMRSFKDLGLDVEAGGTGGSSAVM
TGISEALVATAVGILVAVQAMVFYNYFQARLSRVLVELRLIGDEFVELLKERAAGLPPSEPMPPEPQAAPATRTDAQPA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=154, Percent_Identity=32.4675324675325, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789381, Length=88, Percent_Identity=47.7272727272727, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25460; Mature: 25329

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNDILHYLRLGGVTLAMLIFASVAALIVAVERIIVLWGVGERSRALGETVNKHLLRGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VAAARTAAERSDAVAADIFLAGFDRMERSRTAGGAGIEAAVERERAQVALKLRRYLWILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TIGSITPFVGLFGTVAGIMRSFKDLGLDVEAGGTGGSSAVMTGISEALVATAVGILVAVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AMVFYNYFQARLSRVLVELRLIGDEFVELLKERAAGLPPSEPMPPEPQAAPATRTDAQPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLNDILHYLRLGGVTLAMLIFASVAALIVAVERIIVLWGVGERSRALGETVNKHLLRGD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VAAARTAAERSDAVAADIFLAGFDRMERSRTAGGAGIEAAVERERAQVALKLRRYLWILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TIGSITPFVGLFGTVAGIMRSFKDLGLDVEAGGTGGSSAVMTGISEALVATAVGILVAVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AMVFYNYFQARLSRVLVELRLIGDEFVELLKERAAGLPPSEPMPPEPQAAPATRTDAQPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]