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The map label for this gene is pkn1 [H]

Identifier: 108756974

GI number: 108756974

Start: 4025829

End: 4026878

Strand: Reverse

Name: pkn1 [H]

Synonym: MXAN_3455

Alternate gene names: 108756974

Gene position: 4026878-4025829 (Counterclockwise)

Preceding gene: 108761742

Following gene: 108763634

Centisome position: 44.06

GC content: 68.38

Gene sequence:

>1050_bases
ATGTCGGTAATCCAAGCCGCGCTGGGGAAAGCCCGGGTCCAGCGTGCCAGTGGGGACCTGGAAGGCGCCGCCGCGACGCT
GGATGCGGTGGCCTGGCAGGCACGCGAGGACGTCCTGCCGATGCTCCAGGACGTGTTGGAGCAGCTCACCGTCATCGAGA
ACGGCTTCGTGTTCCGCTATGTCCCCGCGGGCACATTCATCATGGGCAGCGACGACGGCGAACCCGACGAGCGCCCCGCC
CACGCGGTGACGTTGTCCGCGTTCTGGATGAGCGACACATCGCTGTCATGGAGCGCCTTCGCTCGCCTCCTGGATTGGCC
CGAACCGCCCGAGTTCCCCACGGACGAACAACTCGACGGATTCACCGACAGCTTCGCGTACTTCAACGACTCGAAGATTC
GCCTGCAGTACTGCGAGAACGACACCCTGCAGGCCAGTGACTGGCACGCCCACGCCATCCACACGCGATGGGAAACCGGC
GACGGCGTCATCAAGACCTCACAGGAATTGTTCGGCACGCCAGCGCGCGCGGGCGAGGGCCCGCTGCGCTATGACCAGAA
GCCCATGGTCGCGGTCGCCCCTTCGCTCGCGGAACAGTTCGCGCGGCGCTTGAGCACGCCTTCCGTCACCTATCGCCTGC
CCACCGAAGCCGAATGGGAGCGCGCGGCGCGGGGCTGCTTCCGTGGCGCGGCGTACCCATGGGGGAACGAACCTCCAGAC
GCGAGCCGCGCGGACTTCGACCGCTTCAACGACTTCTCGCTCCGCCCCATGCGCGCCTTCCCGCCCAACGACTACGGCCT
CTTCGGCATGGCGGGCGGCGTGAGCCAGTGGTGCCAGGACCACTACGACGCCGAGTACTACCGGCACTCGCCGAAGACGT
CCCCCGTCTGCGTGCTGGGCGAGGACATCCCCAAGCGCACCCACGTCCTGCGCGGCGGCTCGTGGGCGGACTGCGCGGAC
GCGCTGCGGGTCAGCTTCCGCTCCGCGAGCGACACCGGGGCGGCGCCCAACATCGGCTTCCGCCTGGTCCGGGTTCCCTC
ACGGAGGTGA

Upstream 100 bases:

>100_bases
CCGCGTTCGCGGAGGACCCTTGGCAAGCCCAGTCCCTGGGAGCTGCCACGGAGTCACATCCACTGCCCGTGCTCGGCGCG
GAGCGGGGACAGGGGGGCGC

Downstream 100 bases:

>100_bases
GACCAGCGGCTTGTGAGCCGCCCTACCCCACGGCGGCGACCGGAGCCGCGTCGGCGGTCTCCGGAAGCGCGTCGAAGCTC
TCGAACGGGTTCTCCAGCAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSVIQAALGKARVQRASGDLEGAAATLDAVAWQAREDVLPMLQDVLEQLTVIENGFVFRYVPAGTFIMGSDDGEPDERPA
HAVTLSAFWMSDTSLSWSAFARLLDWPEPPEFPTDEQLDGFTDSFAYFNDSKIRLQYCENDTLQASDWHAHAIHTRWETG
DGVIKTSQELFGTPARAGEGPLRYDQKPMVAVAPSLAEQFARRLSTPSVTYRLPTEAEWERAARGCFRGAAYPWGNEPPD
ASRADFDRFNDFSLRPMRAFPPNDYGLFGMAGGVSQWCQDHYDAEYYRHSPKTSPVCVLGEDIPKRTHVLRGGSWADCAD
ALRVSFRSASDTGAAPNIGFRLVRVPSRR

Sequences:

>Translated_349_residues
MSVIQAALGKARVQRASGDLEGAAATLDAVAWQAREDVLPMLQDVLEQLTVIENGFVFRYVPAGTFIMGSDDGEPDERPA
HAVTLSAFWMSDTSLSWSAFARLLDWPEPPEFPTDEQLDGFTDSFAYFNDSKIRLQYCENDTLQASDWHAHAIHTRWETG
DGVIKTSQELFGTPARAGEGPLRYDQKPMVAVAPSLAEQFARRLSTPSVTYRLPTEAEWERAARGCFRGAAYPWGNEPPD
ASRADFDRFNDFSLRPMRAFPPNDYGLFGMAGGVSQWCQDHYDAEYYRHSPKTSPVCVLGEDIPKRTHVLRGGSWADCAD
ALRVSFRSASDTGAAPNIGFRLVRVPSRR
>Mature_348_residues
SVIQAALGKARVQRASGDLEGAAATLDAVAWQAREDVLPMLQDVLEQLTVIENGFVFRYVPAGTFIMGSDDGEPDERPAH
AVTLSAFWMSDTSLSWSAFARLLDWPEPPEFPTDEQLDGFTDSFAYFNDSKIRLQYCENDTLQASDWHAHAIHTRWETGD
GVIKTSQELFGTPARAGEGPLRYDQKPMVAVAPSLAEQFARRLSTPSVTYRLPTEAEWERAARGCFRGAAYPWGNEPPDA
SRADFDRFNDFSLRPMRAFPPNDYGLFGMAGGVSQWCQDHYDAEYYRHSPKTSPVCVLGEDIPKRTHVLRGGSWADCADA
LRVSFRSASDTGAAPNIGFRLVRVPSRR

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=315, Percent_Identity=26.3492063492064, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI257470977, Length=243, Percent_Identity=25.5144032921811, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI194248088, Length=302, Percent_Identity=25.8278145695364, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI194248087, Length=149, Percent_Identity=36.241610738255, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI226437577, Length=149, Percent_Identity=36.241610738255, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 38823; Mature: 38692

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIQAALGKARVQRASGDLEGAAATLDAVAWQAREDVLPMLQDVLEQLTVIENGFVFRY
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VPAGTFIMGSDDGEPDERPAHAVTLSAFWMSDTSLSWSAFARLLDWPEPPEFPTDEQLDG
ECCCEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
FTDSFAYFNDSKIRLQYCENDTLQASDWHAHAIHTRWETGDGVIKTSQELFGTPARAGEG
CCCCCEEECCCEEEEEECCCCCCCCCCCEEEEEEEEECCCCCEEEECHHHHCCCCCCCCC
PLRYDQKPMVAVAPSLAEQFARRLSTPSVTYRLPTEAEWERAARGCFRGAAYPWGNEPPD
CCCCCCCCCEEECHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
ASRADFDRFNDFSLRPMRAFPPNDYGLFGMAGGVSQWCQDHYDAEYYRHSPKTSPVCVLG
CCCCCHHHCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHCCCHHHHCCCCCCCEEEEC
EDIPKRTHVLRGGSWADCADALRVSFRSASDTGAAPNIGFRLVRVPSRR
CCCCCHHHEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SVIQAALGKARVQRASGDLEGAAATLDAVAWQAREDVLPMLQDVLEQLTVIENGFVFRY
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VPAGTFIMGSDDGEPDERPAHAVTLSAFWMSDTSLSWSAFARLLDWPEPPEFPTDEQLDG
ECCCEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
FTDSFAYFNDSKIRLQYCENDTLQASDWHAHAIHTRWETGDGVIKTSQELFGTPARAGEG
CCCCCEEECCCEEEEEECCCCCCCCCCCEEEEEEEEECCCCCEEEECHHHHCCCCCCCCC
PLRYDQKPMVAVAPSLAEQFARRLSTPSVTYRLPTEAEWERAARGCFRGAAYPWGNEPPD
CCCCCCCCCEEECHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
ASRADFDRFNDFSLRPMRAFPPNDYGLFGMAGGVSQWCQDHYDAEYYRHSPKTSPVCVLG
CCCCCHHHCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHCCCHHHHCCCCCCCEEEEC
EDIPKRTHVLRGGSWADCADALRVSFRSASDTGAAPNIGFRLVRVPSRR
CCCCCHHHEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]