| Definition | Helicobacter pylori HPAG1 chromosome, complete genome. |
|---|---|
| Accession | NC_008086 |
| Length | 1,596,366 |
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The map label for this gene is lptD [H]
Identifier: 108563581
GI number: 108563581
Start: 1222146
End: 1224407
Strand: Reverse
Name: lptD [H]
Synonym: HPAG1_1156
Alternate gene names: 108563581
Gene position: 1224407-1222146 (Counterclockwise)
Preceding gene: 108563582
Following gene: 108563580
Centisome position: 76.7
GC content: 37.75
Gene sequence:
>2262_bases ATGATTTATTGGTTGTATTTGGCGGTCTTTTTTTTGTTGAGCGCATTGGAGGCTAAAGAAATCGCTATGCAACGATTTGA CAAACAAAACCATAAGATTTTTGAAATCCTTGCGGATAAAGTGAGCGCTAAAGACAATGTGATAACCGCCTCAGGGAATG CGATCTTATTGAATTATGATGTGTATATTTTAGCGGACAAGGTGCGTTATGACACTAAAACCAAAGAAGCGTTATTAGAG GGGAATATCAAGGTTTATAGGGGCGAGGGTTTGCTCGTCAAAACCGATTATGTGAAATTGAGTTTGAATGAAAAATATGA AATCATTTTCCCCTTTTATGTCCAAGACAGCGTGAGCGGGATTTGGGTGAGCGCGGATATTGCTAGCGGGAAGGATCAAA AATATAAGGTTAAAAACATGAGCGCTTCAGGGTGCAGCATTGATAACCCCATTTGGCATGTCAATGCGACTTCAGGCTCA TTCAACATGCAAAAATCGCATTTGTCTATGTGGAATCCTAAGATCTATGTCGGTGATATTCCTGTATTGTATTTGCCCTA TATTTTCATGTCCACGAGCAATAAAAGAACTACCGGGTTTTTATACCCTGAGTTTGGCACTTCCAATTTAGACGGCTTTA TTTATTTGCAACCCTTTTATTTAGCCCCCAAAAACTCATGGGATATGACCTTTACCCCACAAATCCGCTATAAAAGGGGT TTTGGCTTGAATTTTGAAGCGCGCTACATTAACTCTAAAAACGACAGGTTTTTATTCAATGCGCGCTATTTTAGGAATTA CACTCCATATGTCAAACGCTATGATTTGAGGAATCAAAATATCTATGGGTTTGAATTTTTAAGCTCTAGCAGGGACACTT TACAAAAATACTTTCATCTTAAGTCTAATATTGACAACGGGCATTACATTGACTTTTTATACATGAACGATTTGGACTAT GTGCGTTTTGAAAAGGTTAATAAGCGCATCACGGACGCCACGCACATGTCTAGGGCGAATTACTATTTGCAAACAGAAAA CAATTATTACGGCTTGAATATCAAGTATTTTTTAAACCTGAATAAAATCAACAACAACCGCACTTTCCAATCTGTCCCTA ATTTGCAATACCATAAATATTTAAATTCTTTGTATTTTAGGAATTTATTGTATTCGGTGGATTATCAGTTTAGAAACACC GCAAGAGAGATCGGCTATGGCTATGTGCAAAACGCTTTGAATGTGCCGGTGGGCTTGCAATTTTCTTTGTTTAAAAAGTA TTTGTCTATAGGGCTTTGGAACGATCTCCAACTATCTAATGTGGCTTTAATGCAATCTAAAAATTCCTTCGTGCCTACGA TCCCTAATGAATCAAGGGAATTTGGGAATTTTGTGTCTTCAAATTTTTCCATGTATGTCAATACGGATTTAGCCAGAGAA TACAACAAGCTTTTCCACACGATCCAACTAGAAGCGATTTTCAACATCCCTTATTACACCTTTAAAAACGGCTTATTTTC TCAAAACATGTATGCTTTAAGCGCGCAAGCCTTAAACAGCTACACTTCGCCTTTATTGAGAGATTATGATTATCAAGGGC GTTTGTATGACTCGGTGTGGAATCCTAGTAGCATTTTACCTAGCGATGCGAGCAATAAGACAGTGAATTTAACCCTAACG CAATACCTCTATGGCTTAGGAGGGCAAGAGTTATTGTATTTTAAAATGTCGCAACTCATCAATCTTGACGATAAAGTTTC GCCCTTTAGAATGCCACTAGAGAGCAAGATCGGGTTTTCGCCCTTAACAGGATTGAATATCTTTGGGAATGTCTTTTATT CGTTTTATCAAAACCGATTAGAAGAAATCTCCGTGAACGCCAATTACCAACGCAAGTTTTTAAGCTTTAACCTCTCTTAT TTTTTAAGAAACAATTTCAGCAGTGGGATTAATAGCATTGTAGAAAATCCTGCGGATTATTTAAAGGCGGGTTTTAGCAA CGACTTTGGTTATTTTTCCATGAGCGCGGATGTGGGTTATGATATTAGAAACAATGTGGTTTTAAATTGGAATGTGGGGA TTTATAAAAAAATCCGTTGTTTTGGGATTGGCTTTCAATTCGTCAACCAACGACGCCCTATCCTTACTGGCGATCCCAAC CAGCCTATAAGGGTGTTTGAAAATAACTATGTTAAGCTAGAATTAGACTTTTCACCGATCACTAAAACCAATGTAACTTA CCGCTCTTTACAGCGTAAGTAA
Upstream 100 bases:
>100_bases TTTTTCTATGCCCCTTTTTATGGTTTGTAGTATTTAAAAACCCCTATCATAGGGCGTGGCATGAAGAAAAAAGCAAAAGT CTTTTGGTGTTGTTTTAATC
Downstream 100 bases:
>100_bases GAAAAGGAATGCATTTGAATACGGATTTTAGCCATATCACCGATATAGAGGGCATGCGTTTTATCAATGAAGAAGACGCT TTGAACAAATTGATTAATGA
Product: organic solvent tolerance protein
Products: NA
Alternate protein names: Organic solvent tolerance protein [H]
Number of amino acids: Translated: 753; Mature: 753
Protein sequence:
>753_residues MIYWLYLAVFFLLSALEAKEIAMQRFDKQNHKIFEILADKVSAKDNVITASGNAILLNYDVYILADKVRYDTKTKEALLE GNIKVYRGEGLLVKTDYVKLSLNEKYEIIFPFYVQDSVSGIWVSADIASGKDQKYKVKNMSASGCSIDNPIWHVNATSGS FNMQKSHLSMWNPKIYVGDIPVLYLPYIFMSTSNKRTTGFLYPEFGTSNLDGFIYLQPFYLAPKNSWDMTFTPQIRYKRG FGLNFEARYINSKNDRFLFNARYFRNYTPYVKRYDLRNQNIYGFEFLSSSRDTLQKYFHLKSNIDNGHYIDFLYMNDLDY VRFEKVNKRITDATHMSRANYYLQTENNYYGLNIKYFLNLNKINNNRTFQSVPNLQYHKYLNSLYFRNLLYSVDYQFRNT AREIGYGYVQNALNVPVGLQFSLFKKYLSIGLWNDLQLSNVALMQSKNSFVPTIPNESREFGNFVSSNFSMYVNTDLARE YNKLFHTIQLEAIFNIPYYTFKNGLFSQNMYALSAQALNSYTSPLLRDYDYQGRLYDSVWNPSSILPSDASNKTVNLTLT QYLYGLGGQELLYFKMSQLINLDDKVSPFRMPLESKIGFSPLTGLNIFGNVFYSFYQNRLEEISVNANYQRKFLSFNLSY FLRNNFSSGINSIVENPADYLKAGFSNDFGYFSMSADVGYDIRNNVVLNWNVGIYKKIRCFGIGFQFVNQRRPILTGDPN QPIRVFENNYVKLELDFSPITKTNVTYRSLQRK
Sequences:
>Translated_753_residues MIYWLYLAVFFLLSALEAKEIAMQRFDKQNHKIFEILADKVSAKDNVITASGNAILLNYDVYILADKVRYDTKTKEALLE GNIKVYRGEGLLVKTDYVKLSLNEKYEIIFPFYVQDSVSGIWVSADIASGKDQKYKVKNMSASGCSIDNPIWHVNATSGS FNMQKSHLSMWNPKIYVGDIPVLYLPYIFMSTSNKRTTGFLYPEFGTSNLDGFIYLQPFYLAPKNSWDMTFTPQIRYKRG FGLNFEARYINSKNDRFLFNARYFRNYTPYVKRYDLRNQNIYGFEFLSSSRDTLQKYFHLKSNIDNGHYIDFLYMNDLDY VRFEKVNKRITDATHMSRANYYLQTENNYYGLNIKYFLNLNKINNNRTFQSVPNLQYHKYLNSLYFRNLLYSVDYQFRNT AREIGYGYVQNALNVPVGLQFSLFKKYLSIGLWNDLQLSNVALMQSKNSFVPTIPNESREFGNFVSSNFSMYVNTDLARE YNKLFHTIQLEAIFNIPYYTFKNGLFSQNMYALSAQALNSYTSPLLRDYDYQGRLYDSVWNPSSILPSDASNKTVNLTLT QYLYGLGGQELLYFKMSQLINLDDKVSPFRMPLESKIGFSPLTGLNIFGNVFYSFYQNRLEEISVNANYQRKFLSFNLSY FLRNNFSSGINSIVENPADYLKAGFSNDFGYFSMSADVGYDIRNNVVLNWNVGIYKKIRCFGIGFQFVNQRRPILTGDPN QPIRVFENNYVKLELDFSPITKTNVTYRSLQRK >Mature_753_residues MIYWLYLAVFFLLSALEAKEIAMQRFDKQNHKIFEILADKVSAKDNVITASGNAILLNYDVYILADKVRYDTKTKEALLE GNIKVYRGEGLLVKTDYVKLSLNEKYEIIFPFYVQDSVSGIWVSADIASGKDQKYKVKNMSASGCSIDNPIWHVNATSGS FNMQKSHLSMWNPKIYVGDIPVLYLPYIFMSTSNKRTTGFLYPEFGTSNLDGFIYLQPFYLAPKNSWDMTFTPQIRYKRG FGLNFEARYINSKNDRFLFNARYFRNYTPYVKRYDLRNQNIYGFEFLSSSRDTLQKYFHLKSNIDNGHYIDFLYMNDLDY VRFEKVNKRITDATHMSRANYYLQTENNYYGLNIKYFLNLNKINNNRTFQSVPNLQYHKYLNSLYFRNLLYSVDYQFRNT AREIGYGYVQNALNVPVGLQFSLFKKYLSIGLWNDLQLSNVALMQSKNSFVPTIPNESREFGNFVSSNFSMYVNTDLARE YNKLFHTIQLEAIFNIPYYTFKNGLFSQNMYALSAQALNSYTSPLLRDYDYQGRLYDSVWNPSSILPSDASNKTVNLTLT QYLYGLGGQELLYFKMSQLINLDDKVSPFRMPLESKIGFSPLTGLNIFGNVFYSFYQNRLEEISVNANYQRKFLSFNLSY FLRNNFSSGINSIVENPADYLKAGFSNDFGYFSMSADVGYDIRNNVVLNWNVGIYKKIRCFGIGFQFVNQRRPILTGDPN QPIRVFENNYVKLELDFSPITKTNVTYRSLQRK
Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]
COG id: COG1452
COG function: function code M; Organic solvent tolerance protein OstA
Gene ontology:
Cell location: Cell outer membrane [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the lptD family [H]
Homologues:
None
Paralogues:
None
Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020889 - InterPro: IPR005653 - InterPro: IPR007543 [H]
Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]
EC number: NA
Molecular weight: Translated: 87953; Mature: 87953
Theoretical pI: Translated: 9.56; Mature: 9.56
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIYWLYLAVFFLLSALEAKEIAMQRFDKQNHKIFEILADKVSAKDNVITASGNAILLNYD CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEE VYILADKVRYDTKTKEALLEGNIKVYRGEGLLVKTDYVKLSLNEKYEIIFPFYVQDSVSG EEEEEECEECCCHHHHHHHCCCEEEEECCEEEEEEEEEEEEECCCEEEEEEEEEECCCCE IWVSADIASGKDQKYKVKNMSASGCSIDNPIWHVNATSGSFNMQKSHLSMWNPKIYVGDI EEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHCCCEEEECCC PVLYLPYIFMSTSNKRTTGFLYPEFGTSNLDGFIYLQPFYLAPKNSWDMTFTPQIRYKRG CHHHHCEEEEECCCCCEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCEEECCCEEEECC FGLNFEARYINSKNDRFLFNARYFRNYTPYVKRYDLRNQNIYGFEFLSSSRDTLQKYFHL CCCCEEEEEECCCCCEEEEEEHHHCCCCCHHEEEECCCCCEEEEEECCCCHHHHHHHHHH KSNIDNGHYIDFLYMNDLDYVRFEKVNKRITDATHMSRANYYLQTENNYYGLNIKYFLNL HCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEEEEEE NKINNNRTFQSVPNLQYHKYLNSLYFRNLLYSVDYQFRNTAREIGYGYVQNALNVPVGLQ EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCCCC FSLFKKYLSIGLWNDLQLSNVALMQSKNSFVPTIPNESREFGNFVSSNFSMYVNTDLARE HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEECHHHHH YNKLFHTIQLEAIFNIPYYTFKNGLFSQNMYALSAQALNSYTSPLLRDYDYQGRLYDSVW HHHHHHEEEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCEEEECCC NPSSILPSDASNKTVNLTLTQYLYGLGGQELLYFKMSQLINLDDKVSPFRMPLESKIGFS CCCCCCCCCCCCCEEEEEHHHHHHCCCCCEEHEEEHHHHCCCCCCCCCCCCCHHHCCCCC PLTGLNIFGNVFYSFYQNRLEEISVNANYQRKFLSFNLSYFLRNNFSSGINSIVENPADY CCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEEEEECCCHHHHHHHHHHCCHHH LKAGFSNDFGYFSMSADVGYDIRNNVVLNWNVGIYKKIRCFGIGFQFVNQRRPILTGDPN HHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCEEEEEEEEECHHHHCCCCCEEECCCC QPIRVFENNYVKLELDFSPITKTNVTYRSLQRK CCEEEEECCEEEEEEECCCCCCCCCCHHHHCCC >Mature Secondary Structure MIYWLYLAVFFLLSALEAKEIAMQRFDKQNHKIFEILADKVSAKDNVITASGNAILLNYD CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEE VYILADKVRYDTKTKEALLEGNIKVYRGEGLLVKTDYVKLSLNEKYEIIFPFYVQDSVSG EEEEEECEECCCHHHHHHHCCCEEEEECCEEEEEEEEEEEEECCCEEEEEEEEEECCCCE IWVSADIASGKDQKYKVKNMSASGCSIDNPIWHVNATSGSFNMQKSHLSMWNPKIYVGDI EEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHCCCEEEECCC PVLYLPYIFMSTSNKRTTGFLYPEFGTSNLDGFIYLQPFYLAPKNSWDMTFTPQIRYKRG CHHHHCEEEEECCCCCEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCEEECCCEEEECC FGLNFEARYINSKNDRFLFNARYFRNYTPYVKRYDLRNQNIYGFEFLSSSRDTLQKYFHL CCCCEEEEEECCCCCEEEEEEHHHCCCCCHHEEEECCCCCEEEEEECCCCHHHHHHHHHH KSNIDNGHYIDFLYMNDLDYVRFEKVNKRITDATHMSRANYYLQTENNYYGLNIKYFLNL HCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEEEEEE NKINNNRTFQSVPNLQYHKYLNSLYFRNLLYSVDYQFRNTAREIGYGYVQNALNVPVGLQ EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCCCC FSLFKKYLSIGLWNDLQLSNVALMQSKNSFVPTIPNESREFGNFVSSNFSMYVNTDLARE HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEECHHHHH YNKLFHTIQLEAIFNIPYYTFKNGLFSQNMYALSAQALNSYTSPLLRDYDYQGRLYDSVW HHHHHHEEEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCEEEECCC NPSSILPSDASNKTVNLTLTQYLYGLGGQELLYFKMSQLINLDDKVSPFRMPLESKIGFS CCCCCCCCCCCCCEEEEEHHHHHHCCCCCEEHEEEHHHHCCCCCCCCCCCCCHHHCCCCC PLTGLNIFGNVFYSFYQNRLEEISVNANYQRKFLSFNLSYFLRNNFSSGINSIVENPADY CCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEEEEECCCHHHHHHHHHHCCHHH LKAGFSNDFGYFSMSADVGYDIRNNVVLNWNVGIYKKIRCFGIGFQFVNQRRPILTGDPN HHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCEEEEEEEEECHHHHCCCCCEEECCCC QPIRVFENNYVKLELDFSPITKTNVTYRSLQRK CCEEEEECCEEEEEEECCCCCCCCCCHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 12024217 [H]