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The map label for this gene is pgl [H]

Identifier: 108563465

GI number: 108563465

Start: 1095403

End: 1096086

Strand: Direct

Name: pgl [H]

Synonym: HPAG1_1040

Alternate gene names: 108563465

Gene position: 1095403-1096086 (Clockwise)

Preceding gene: 108563464

Following gene: 108563466

Centisome position: 68.62

GC content: 39.04

Gene sequence:

>684_bases
ATGGGTTATCAATTGTTTGAATTTGAAAATTTGAAAGATTGCCACAAGGCTTTAATAGAGCGTTTTAAAGAATTTTTTAA
CACCGCCTTAAAAAAGCACCATCAAGTTTCTATCGCTTTTTCTGGGGGCCGTTCGCCCATTAGCTTGTTGCAAAAATTAA
GCGTTTTAGATCTCAAATGGCATGAGTGTTTAATCAGTTTGGTAGATGAACGCATTATAGACACAAGCCACAAGGATAGC
AACACCAAATTATTACACGACTACTTGTTGCAAAATAACGCCTTAAAAGCTTCTTTCACCCCGCTTTTGCCCAAAAAGAT
TTCTAGCGATACAAACGCGCTTTTTCATTTTGCTAACCAGCATTTCAAACAGCCCCATTTAGCCATTTTGGGCATGGGGA
CTGATGGGCATACGGCTAGCCTTTTTCCTGAAACGAGCGCTTTTTTAAACGAAGAAAAAGAAAATATCGTTTTGACTAAG
CCCGCTAACGCTCCTTATGAGCGCCTGAGCATGTCTGTTAACGCCTTAGAAAATTGCGAAAAACTTTTCTTAAGCATTAG
CGGAGTAGAAAAAAGGGAGGTTTTAGAAAAGGCTTTAAAAGAAAACGCTCCCTATTCTCTGCCGATTGCTCGGATTTTAC
ATTCTAAAAAAGTTACCACGGAGGTGTTTTATGCCAAAAACTGA

Upstream 100 bases:

>100_bases
GAGGGCTTTATGAATAACGCCACGCCCTTACATTCCTATGAAAGCCATAATCTCAACGAATCCGAATTTTTAAAACCACT
CTATCAATAAAAGGGATTTC

Downstream 100 bases:

>100_bases
AACTTACCCAAGACTATTAGCCGATATTGGCGGCACGAACGCACGCTTTGGTTTGGAAGTCGCCCCACGACAGATTGAAT
GCATTGAAGTCTTGCGGTGC

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MGYQLFEFENLKDCHKALIERFKEFFNTALKKHHQVSIAFSGGRSPISLLQKLSVLDLKWHECLISLVDERIIDTSHKDS
NTKLLHDYLLQNNALKASFTPLLPKKISSDTNALFHFANQHFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLTK
PANAPYERLSMSVNALENCEKLFLSISGVEKREVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN

Sequences:

>Translated_227_residues
MGYQLFEFENLKDCHKALIERFKEFFNTALKKHHQVSIAFSGGRSPISLLQKLSVLDLKWHECLISLVDERIIDTSHKDS
NTKLLHDYLLQNNALKASFTPLLPKKISSDTNALFHFANQHFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLTK
PANAPYERLSMSVNALENCEKLFLSISGVEKREVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN
>Mature_226_residues
GYQLFEFENLKDCHKALIERFKEFFNTALKKHHQVSIAFSGGRSPISLLQKLSVLDLKWHECLISLVDERIIDTSHKDSN
TKLLHDYLLQNNALKASFTPLLPKKISSDTNALFHFANQHFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLTKP
ANAPYERLSMSVNALENCEKLFLSISGVEKREVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=209, Percent_Identity=30.622009569378, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25780; Mature: 25649

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYQLFEFENLKDCHKALIERFKEFFNTALKKHHQVSIAFSGGRSPISLLQKLSVLDLKW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHH
HECLISLVDERIIDTSHKDSNTKLLHDYLLQNNALKASFTPLLPKKISSDTNALFHFANQ
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHH
HFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLTKPANAPYERLSMSVNALENCE
HCCCCCEEEEEECCCCCCEECCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
KLFLSISGVEKREVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN
HHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHEEEEECC
>Mature Secondary Structure 
GYQLFEFENLKDCHKALIERFKEFFNTALKKHHQVSIAFSGGRSPISLLQKLSVLDLKW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHH
HECLISLVDERIIDTSHKDSNTKLLHDYLLQNNALKASFTPLLPKKISSDTNALFHFANQ
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHH
HFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLTKPANAPYERLSMSVNALENCE
HCCCCCEEEEEECCCCCCEECCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
KLFLSISGVEKREVLEKALKENAPYSLPIARILHSKKVTTEVFYAKN
HHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]