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The map label for this gene is glk [H]

Identifier: 108563466

GI number: 108563466

Start: 1096073

End: 1097083

Strand: Direct

Name: glk [H]

Synonym: HPAG1_1041

Alternate gene names: 108563466

Gene position: 1096073-1097083 (Clockwise)

Preceding gene: 108563465

Following gene: 108563467

Centisome position: 68.66

GC content: 46.49

Gene sequence:

>1011_bases
ATGCCAAAAACTGAAACTTACCCAAGACTATTAGCCGATATTGGCGGCACGAACGCACGCTTTGGTTTGGAAGTCGCCCC
ACGACAGATTGAATGCATTGAAGTCTTGCGGTGCGAAGATTTTGAGAGCTTGAGCGATGCGGTGCGGTTTTACCTTTCTA
AATGCAAAGAAAGCCTTAAACTGCACCCTATTTATGGCTCTTTTGCTGTGGCTACGCCCATTATGGGGGATTTTGTCCAA
ATGACGAACAACCATTGGACTTTTTCTATTGAAACGACACGGCAATGTTTGACTTTAAAAAAATTGCTTGTCATCAATGA
TTTTGTCGCGCAAGCCTATGCCATTAGCGCGATGCAAGAAAACGATCTGGCTCAAATAGGCGGGATTAAGTGCGAAATCA
ACGCTCCTAAAGCGATTTTAGGGCCAGGAACCGGGCTTGGGGTAAGCACTCTTATCCAAAACAGCGATGGCTCTTTAAAA
GTCTTGCCCGGTGAAGGAGGGCATGTGAGCTTTGCCCCTTTTGACGATCTAGAAATTTTAGTGTGGCAATACGCCCGCTC
TAAATTCAATCATGTGAGCGCGGAAAGGTTTTTGAGCGGGAGCGGTCTGGTGCTGATTTATGAAGCCCTGTCTAAACGCA
AAGGCTTAGAAAAAGTGGCGAAGTTAAGCAAGGCTGAATTAACCCCACAAATCATTAGCGAACGCGCTTTGAATGGGGAT
TACCCTATATGCCGATTGACCTTGGACACTTTTTGCTCCATGCTAGGCACGCTCGCTGCTGATGTGGCTCTCACTTTGGG
GGCTAGGGGGGGCGTGTATTTGTGTGGGGGGATTATCCCACGATTCATTGATTATTTTAAAACTTCGCCCTTTAGAGCGC
GTTTTGAAACGAAAGGGCGCATGGGAGCGTTTCTCGCTTCTATCCCTGTGCATGTCGTGATGAAAAAAACTCCGGGACTT
GATGGGGCAGGCATTGCGTTAGAGAATTATTTACTGCATGATAAAATTTAG

Upstream 100 bases:

>100_bases
AAAAGGGAGGTTTTAGAAAAGGCTTTAAAAGAAAACGCTCCCTATTCTCTGCCGATTGCTCGGATTTTACATTCTAAAAA
AGTTACCACGGAGGTGTTTT

Downstream 100 bases:

>100_bases
CAAGTAGTAGCCGCTTAAGATAAAAGCGATTAGTGTAAGGGGTGCGTTTAAACGCGCCAAACAACGATACCATATAGCCA
ATAACTATCAAATTAGTTAA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPKTETYPRLLADIGGTNARFGLEVAPRQIECIEVLRCEDFESLSDAVRFYLSKCKESLKLHPIYGSFAVATPIMGDFVQ
MTNNHWTFSIETTRQCLTLKKLLVINDFVAQAYAISAMQENDLAQIGGIKCEINAPKAILGPGTGLGVSTLIQNSDGSLK
VLPGEGGHVSFAPFDDLEILVWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKGLEKVAKLSKAELTPQIISERALNGD
YPICRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGRMGAFLASIPVHVVMKKTPGL
DGAGIALENYLLHDKI

Sequences:

>Translated_336_residues
MPKTETYPRLLADIGGTNARFGLEVAPRQIECIEVLRCEDFESLSDAVRFYLSKCKESLKLHPIYGSFAVATPIMGDFVQ
MTNNHWTFSIETTRQCLTLKKLLVINDFVAQAYAISAMQENDLAQIGGIKCEINAPKAILGPGTGLGVSTLIQNSDGSLK
VLPGEGGHVSFAPFDDLEILVWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKGLEKVAKLSKAELTPQIISERALNGD
YPICRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGRMGAFLASIPVHVVMKKTPGL
DGAGIALENYLLHDKI
>Mature_335_residues
PKTETYPRLLADIGGTNARFGLEVAPRQIECIEVLRCEDFESLSDAVRFYLSKCKESLKLHPIYGSFAVATPIMGDFVQM
TNNHWTFSIETTRQCLTLKKLLVINDFVAQAYAISAMQENDLAQIGGIKCEINAPKAILGPGTGLGVSTLIQNSDGSLKV
LPGEGGHVSFAPFDDLEILVWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKGLEKVAKLSKAELTPQIISERALNGDY
PICRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGRMGAFLASIPVHVVMKKTPGLD
GAGIALENYLLHDKI

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=325, Percent_Identity=41.5384615384615, Blast_Score=238, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 36732; Mature: 36601

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTETYPRLLADIGGTNARFGLEVAPRQIECIEVLRCEDFESLSDAVRFYLSKCKESLK
CCCCCHHHHHHHHCCCCCCEECEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCE
LHPIYGSFAVATPIMGDFVQMTNNHWTFSIETTRQCLTLKKLLVINDFVAQAYAISAMQE
EEECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDLAQIGGIKCEINAPKAILGPGTGLGVSTLIQNSDGSLKVLPGEGGHVSFAPFDDLEIL
CCHHHHCCEEEEECCCCEEECCCCCCCHHHHEECCCCCEEEECCCCCEEEECCCCCHHHH
VWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKGLEKVAKLSKAELTPQIISERALNGD
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCC
YPICRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGR
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCEECCCCCC
MGAFLASIPVHVVMKKTPGLDGAGIALENYLLHDKI
HHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
PKTETYPRLLADIGGTNARFGLEVAPRQIECIEVLRCEDFESLSDAVRFYLSKCKESLK
CCCCHHHHHHHHCCCCCCEECEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCE
LHPIYGSFAVATPIMGDFVQMTNNHWTFSIETTRQCLTLKKLLVINDFVAQAYAISAMQE
EEECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDLAQIGGIKCEINAPKAILGPGTGLGVSTLIQNSDGSLKVLPGEGGHVSFAPFDDLEIL
CCHHHHCCEEEEECCCCEEECCCCCCCHHHHEECCCCCEEEECCCCCEEEECCCCCHHHH
VWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKGLEKVAKLSKAELTPQIISERALNGD
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCC
YPICRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGR
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCEECCCCCC
MGAFLASIPVHVVMKKTPGLDGAGIALENYLLHDKI
HHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA