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The map label for this gene is era [H]

Identifier: 108562916

GI number: 108562916

Start: 509873

End: 510778

Strand: Direct

Name: era [H]

Synonym: HPAG1_0491

Alternate gene names: 108562916

Gene position: 509873-510778 (Clockwise)

Preceding gene: 108562915

Following gene: 108562917

Centisome position: 31.94

GC content: 37.42

Gene sequence:

>906_bases
ATGAAAAATAAGGCGGGCTTTGTAGCTCTTATAGGCAAACCAAACGCTGGAAAAAGCACTCTTTTAAACACTTTATTAAA
CGCTCATTTAGCCCTTGTTTCGCATAAGGCTAATGCGACCAGAAAATTGATGAAATGCATCGTGCCTTTTAAAGATAAAG
AAGGGTATGAGAGCCAAATCATTTTTTTAGACACACCAGGGCTCCATCATCAAGAAAAATTACTCAACCAATGCATGCTC
TCACAGGCTTTAAAAGCGATGGGCGATGCTGAATTGTGCGTTTTTTTAGCTTCTGTGCATGATGATTTAAAAGGGTATGA
AGAGTTTTTGAGTTTGTGCCAAAAACCTCATATCTTGGCTTTGAGTAAGATTGATATGGCCACGCATAAGCAGGTTTTGC
AAAAATTACAAGAGTATCAACAATACAATTCGCAATTTTTAGCCCTAGTGCCTTTGAGTGCAAAAAAATCTCAAAATTTA
AACGCGCTTTTAGAATGCATCAGCAAGCATTTAATCCCTAGCGCATGGCTTTTTGAAAAGGATTTGATGAGCGATGAAAA
AATGCGCGATATTTATAAGGAAATCATTAGGGAGAGTTTGTTTGATTTTTTGAGCGATGAAATCCCTTATGAAAGCGATG
TGGTGATTGATAAATTTATAGAAGAAGAACGCATAGACAAGGTGTATGCGCGTATTATCGTAGAAAAAGAAAGCCAAAAA
AAAATCGTGATAGGCAAAAACGGGGTGAATATCAAACGCATCGGGACTAGTGCTAGATTGAAAATGCAAGAAGTGGGCGA
AAAAAAGGTTTTTTTAAACTTGCAAGTGATCGCTCAAAAATCATGGAGCAAGGAAGAAAAGAGCTTGCAAAAACTGGGTT
ATACCCATCAAAGGAATAGGGATTGA

Upstream 100 bases:

>100_bases
AGGATTATTTGGGGCAAAAGGTTACTATCACTAAAGAATTGGTTCAATCAAAGCTAGAGGATTTAGTGGCTGATGAAAAT
TTAGTGAAGTATATTTTATA

Downstream 100 bases:

>100_bases
AAAAGGTATTACCGGCTTTATTAATGGGGTTTGTGGGCTTGAATGCTGATGAGCGTTTGTTGGAAATCATGCACCTTTAT
CAAAAACAAGGCTTGGAAGT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKNKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQIIFLDTPGLHHQEKLLNQCML
SQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILALSKIDMATHKQVLQKLQEYQQYNSQFLALVPLSAKKSQNL
NALLECISKHLIPSAWLFEKDLMSDEKMRDIYKEIIRESLFDFLSDEIPYESDVVIDKFIEEERIDKVYARIIVEKESQK
KIVIGKNGVNIKRIGTSARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYTHQRNRD

Sequences:

>Translated_301_residues
MKNKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQIIFLDTPGLHHQEKLLNQCML
SQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILALSKIDMATHKQVLQKLQEYQQYNSQFLALVPLSAKKSQNL
NALLECISKHLIPSAWLFEKDLMSDEKMRDIYKEIIRESLFDFLSDEIPYESDVVIDKFIEEERIDKVYARIIVEKESQK
KIVIGKNGVNIKRIGTSARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYTHQRNRD
>Mature_301_residues
MKNKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQIIFLDTPGLHHQEKLLNQCML
SQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILALSKIDMATHKQVLQKLQEYQQYNSQFLALVPLSAKKSQNL
NALLECISKHLIPSAWLFEKDLMSDEKMRDIYKEIIRESLFDFLSDEIPYESDVVIDKFIEEERIDKVYARIIVEKESQK
KIVIGKNGVNIKRIGTSARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYTHQRNRD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=311, Percent_Identity=27.9742765273312, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788919, Length=299, Percent_Identity=37.7926421404682, Blast_Score=187, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34432; Mature: 34432

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQI
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
IFLDTPGLHHQEKLLNQCMLSQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILA
EEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LSKIDMATHKQVLQKLQEYQQYNSQFLALVPLSAKKSQNLNALLECISKHLIPSAWLFEK
EHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHH
DLMSDEKMRDIYKEIIRESLFDFLSDEIPYESDVVIDKFIEEERIDKVYARIIVEKESQK
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
KIVIGKNGVNIKRIGTSARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYTHQRNR
EEEEECCCCEEEEECCHHHHHHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHCCCCCCCC
D
C
>Mature Secondary Structure
MKNKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQI
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
IFLDTPGLHHQEKLLNQCMLSQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILA
EEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LSKIDMATHKQVLQKLQEYQQYNSQFLALVPLSAKKSQNLNALLECISKHLIPSAWLFEK
EHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHH
DLMSDEKMRDIYKEIIRESLFDFLSDEIPYESDVVIDKFIEEERIDKVYARIIVEKESQK
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
KIVIGKNGVNIKRIGTSARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYTHQRNR
EEEEECCCCEEEEECCHHHHHHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHCCCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA