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The map label for this gene is pgbA [H]

Identifier: 108562907

GI number: 108562907

Start: 499594

End: 500913

Strand: Direct

Name: pgbA [H]

Synonym: HPAG1_0482

Alternate gene names: 108562907

Gene position: 499594-500913 (Clockwise)

Preceding gene: 108562906

Following gene: 108562908

Centisome position: 31.3

GC content: 37.58

Gene sequence:

>1320_bases
ATGAGTTTTATAAGCTTGCAATCAGCCTCTTGGCAAGAACCCTTAAGAGTGAGTATAGAATTTGTGGATTTGCCTAAAAA
AATCATTCGTTTTCCGGCCCATGATTTGAAAGTGGGGGAGTTTGGTTTTGTGGTTACTAAACTTTCAGATTATGAAATCG
TTAATTCTGAAGTGGTCATTATTGCTGTTGAAAATGGCGTTGCAACGGCTAAATTCAAAGCGTTTGAGTCGATGAAACAA
AGCCATTTACCCACTCCAAGAATGGTCGCTAAAAAAGGGGATTTAGTCTATTTTAGGCAATTCAACAACCAAGCGTTTTT
AATCGCTCCTAATGATGAAATCTATGAGCAAATCAGAGCGACTAACACCGATATTAATTTTATTAGCTCTGATTTGTTGG
TTACTTTTTTGAATGGGTTTGACCCAAAAATCGCTAATTTAAGAAAAGCGTGCAACGTTTATAGCGTGGGGGTGATTTAT
ATTGTAACCACGAACACGCTCAATATTTTAAGCTGTGAGAGTTTTGAAATTTTAGAAAAAAGAGAGCTGGATACAAGCGG
TGTTACTAAAACTTCCACGCCGTTTTTTTCTAGGGTTGAGGGCATTGATGCAGGCACGCTAGGGAAACTTTTTTCAGGCA
GTCAGTCTAAAAATTACTTCGCTTACTATGACGCTTTAGTGAAAAAAGAAAAACGCAAAGAAGTGAGGATTAAAAAGCAA
GAAGGAAAGATTGATTCTAGAGAAATTAAACGAGAAATCAAGCAAGAAGTCATTAAAGAGCCTAAAAAAGCCAATCAAGG
CACAGAAAACGCTCCCACTTTAGAAGAGAAAAACTACCAAAAAGCAGAGCGAAAACTTGACGCTAAAGAAGAAAGGCGCT
ATTTAAGAGATGAAAGGAAAAAAGCCAAAGCCACCAAAAAGGCTATGGAATTTGAAGAAAGAGAAAAAGAGCATGATGAA
AGAGACGAAAAAGAGACTGAAGGAAGAAGAAAAGCTTTAGAAATGGATAAAGGCAATGAAAAAGTCAATGCCAAAGAAAA
TGAGCAAGAAATCAAGCAAGAAGCCATTAAAGAGCCAAGCAATGGAGATAACGCCACCCAACAAGGCGAAAAACAAAACG
CTCCTAAAGAGAACAAGGCTTCTAAAGAAGAGAATAAACCAAATTCTAAAGAAGAAAAACGCCGCTTGAAAGAAGAAAAG
AAAAAAGCCAAAGCCGAACAAAGAGCGAGAGAATTTGAACAAAGAGCGAGAGAGCATCAAGAAAGAGATGAAAAAGAGCT
TGAAGAGCGAAGAAAGGCGCTAGAAGCGGGTAAAAAATAA

Upstream 100 bases:

>100_bases
AAAACCACCGGCTTGTCTTTAGCCATTTTGTGGCATTTAAAAAAGTTTAAAAATATTTAAAAGGAATTTTATGTTAAGGC
TTTTGATAGGACTTCTTTTA

Downstream 100 bases:

>100_bases
CATGTTAGAACAACAGCACATTAAATATTTTAAAAACCTAGTGGGGGGAGAGGATTTTTTCACTGATTTAGCGCATTTGA
ACGCTTATTGCTATGACGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSFISLQSASWQEPLRVSIEFVDLPKKIIRFPAHDLKVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATAKFKAFESMKQ
SHLPTPRMVAKKGDLVYFRQFNNQAFLIAPNDEIYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIY
IVTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKLFSGSQSKNYFAYYDALVKKEKRKEVRIKKQ
EGKIDSREIKREIKQEVIKEPKKANQGTENAPTLEEKNYQKAERKLDAKEERRYLRDERKKAKATKKAMEFEEREKEHDE
RDEKETEGRRKALEMDKGNEKVNAKENEQEIKQEAIKEPSNGDNATQQGEKQNAPKENKASKEENKPNSKEEKRRLKEEK
KKAKAEQRAREFEQRAREHQERDEKELEERRKALEAGKK

Sequences:

>Translated_439_residues
MSFISLQSASWQEPLRVSIEFVDLPKKIIRFPAHDLKVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATAKFKAFESMKQ
SHLPTPRMVAKKGDLVYFRQFNNQAFLIAPNDEIYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIY
IVTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKLFSGSQSKNYFAYYDALVKKEKRKEVRIKKQ
EGKIDSREIKREIKQEVIKEPKKANQGTENAPTLEEKNYQKAERKLDAKEERRYLRDERKKAKATKKAMEFEEREKEHDE
RDEKETEGRRKALEMDKGNEKVNAKENEQEIKQEAIKEPSNGDNATQQGEKQNAPKENKASKEENKPNSKEEKRRLKEEK
KKAKAEQRAREFEQRAREHQERDEKELEERRKALEAGKK
>Mature_438_residues
SFISLQSASWQEPLRVSIEFVDLPKKIIRFPAHDLKVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATAKFKAFESMKQS
HLPTPRMVAKKGDLVYFRQFNNQAFLIAPNDEIYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIYI
VTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKLFSGSQSKNYFAYYDALVKKEKRKEVRIKKQE
GKIDSREIKREIKQEVIKEPKKANQGTENAPTLEEKNYQKAERKLDAKEERRYLRDERKKAKATKKAMEFEEREKEHDER
DEKETEGRRKALEMDKGNEKVNAKENEQEIKQEAIKEPSNGDNATQQGEKQNAPKENKASKEENKPNSKEEKRRLKEEKK
KAKAEQRAREFEQRAREHQERDEKELEERRKALEAGKK

Specific function: Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.py

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface (Probable). Note=The plasminogen-binding region is localized on the surface the bacterium (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50814; Mature: 50683

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFISLQSASWQEPLRVSIEFVDLPKKIIRFPAHDLKVGEFGFVVTKLSDYEIVNSEVVI
CCCEECCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCEECCHHEEEEECCCCEEECCCEEE
IAVENGVATAKFKAFESMKQSHLPTPRMVAKKGDLVYFRQFNNQAFLIAPNDEIYEQIRA
EEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEECCCCEEEECCCHHHHHHHHH
TNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIYIVTTNTLNILSCESFEILEK
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEEEEEECCEEEEECCCHHHHHH
RELDTSGVTKTSTPFFSRVEGIDAGTLGKLFSGSQSKNYFAYYDALVKKEKRKEVRIKKQ
HCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEHH
EGKIDSREIKREIKQEVIKEPKKANQGTENAPTLEEKNYQKAERKLDAKEERRYLRDERK
CCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
KAKATKKAMEFEEREKEHDERDEKETEGRRKALEMDKGNEKVNAKENEQEIKQEAIKEPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
NGDNATQQGEKQNAPKENKASKEENKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQ
CCCCHHHCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERDEKELEERRKALEAGKK
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFISLQSASWQEPLRVSIEFVDLPKKIIRFPAHDLKVGEFGFVVTKLSDYEIVNSEVVI
CCEECCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCEECCHHEEEEECCCCEEECCCEEE
IAVENGVATAKFKAFESMKQSHLPTPRMVAKKGDLVYFRQFNNQAFLIAPNDEIYEQIRA
EEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEECCCCEEEECCCHHHHHHHHH
TNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIYIVTTNTLNILSCESFEILEK
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEEEEEECCEEEEECCCHHHHHH
RELDTSGVTKTSTPFFSRVEGIDAGTLGKLFSGSQSKNYFAYYDALVKKEKRKEVRIKKQ
HCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEHH
EGKIDSREIKREIKQEVIKEPKKANQGTENAPTLEEKNYQKAERKLDAKEERRYLRDERK
CCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
KAKATKKAMEFEEREKEHDERDEKETEGRRKALEMDKGNEKVNAKENEQEIKQEAIKEPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
NGDNATQQGEKQNAPKENKASKEENKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQ
CCCCHHHCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERDEKELEERRKALEAGKK
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]