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The map label for this gene is neuA [H]

Identifier: 108562754

GI number: 108562754

Start: 340952

End: 341641

Strand: Direct

Name: neuA [H]

Synonym: HPAG1_0329

Alternate gene names: 108562754

Gene position: 340952-341641 (Clockwise)

Preceding gene: 108562753

Following gene: 108562755

Centisome position: 21.36

GC content: 37.68

Gene sequence:

>690_bases
ATGAGAGCGATCGCTATTGTTTTAGCCAGAAGTTCCAGTAAAAGAATCAAGAATAAAAATATTATTGATTTTTTCAATAA
ACCCATGCTGGCTTACCCTATTGAAGCGGCACTAAATTCCAAGCTCTTTGAAAAGGTGTTTATCTCTAGCGATAGCATGG
AGTATGTGAATTTAGCTAAAAATTATGGGGCGAGTTTTTTGAATTTACGCCCTAAAAATTTAGCAGATGACAGAGCCACG
ACTTTAGAGGTGATGGCCTATCACATGAAAGAATTAGAGTTAAAAGATGAAGACATTGCGTGTTGTTTGTATGGCGCTTC
AGTATTTTTACAAAAAAAGCATTTAAAAAACGCTTTTGAAACTTTAAAACAAAATCAAAATACGGATTATGTCTTCACAT
GCTCTCCCTTTAGCGCTTCGCCCTATCGTTCTTTTAGCCTTGAAAACGGCGTTCAAATGGCTTTTAAAGAGCATTCAAAC
ACGCGCACGCAAGATCTAAAAACGCTCTATCATGACGCAGGGTTGCTTTATATGGGGAAGGCTCAAGCCTTTAAAGAAAT
GCGGCCTATTTTTAGCCCAAATTCCATCGCTTTAGAATTATCGCCCTTAGAAGTCCAAGACATTGACACTTTAGAAGATT
TAGAATTAGCCAAGCTCAAATACAGCCGTTTGAAAAACGCATGCCAGTAA

Upstream 100 bases:

>100_bases
ATACACGAATTTAGGGCATTTGAGCGATTCCAATAAAAAGAAATTCGCTGCTGATGCGATGGAAACCCAAATGCCTTATT
AATAAAGAGCAAAGCCTAGC

Downstream 100 bases:

>100_bases
AAATTTTGTGCGATTGTTTTTTAACAAGCGGTTTAGGGCATGTGAGGCGTTGTGAAAAAATCCTTTCTTTTATAGAAAAA
TTAGGAGTTAAAGTGGATCT

Product: CMP-N-acetylneuraminic acid synthetase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MRAIAIVLARSSSKRIKNKNIIDFFNKPMLAYPIEAALNSKLFEKVFISSDSMEYVNLAKNYGASFLNLRPKNLADDRAT
TLEVMAYHMKELELKDEDIACCLYGASVFLQKKHLKNAFETLKQNQNTDYVFTCSPFSASPYRSFSLENGVQMAFKEHSN
TRTQDLKTLYHDAGLLYMGKAQAFKEMRPIFSPNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNACQ

Sequences:

>Translated_229_residues
MRAIAIVLARSSSKRIKNKNIIDFFNKPMLAYPIEAALNSKLFEKVFISSDSMEYVNLAKNYGASFLNLRPKNLADDRAT
TLEVMAYHMKELELKDEDIACCLYGASVFLQKKHLKNAFETLKQNQNTDYVFTCSPFSASPYRSFSLENGVQMAFKEHSN
TRTQDLKTLYHDAGLLYMGKAQAFKEMRPIFSPNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNACQ
>Mature_229_residues
MRAIAIVLARSSSKRIKNKNIIDFFNKPMLAYPIEAALNSKLFEKVFISSDSMEYVNLAKNYGASFLNLRPKNLADDRAT
TLEVMAYHMKELELKDEDIACCLYGASVFLQKKHLKNAFETLKQNQNTDYVFTCSPFSASPYRSFSLENGVQMAFKEHSN
TRTQDLKTLYHDAGLLYMGKAQAFKEMRPIFSPNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNACQ

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR013830
- InterPro:   IPR013831 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 26122; Mature: 26122

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIAIVLARSSSKRIKNKNIIDFFNKPMLAYPIEAALNSKLFEKVFISSDSMEYVNLAK
CCEEEEEEECCCCHHHCCCCHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCCHHHHHHHH
NYGASFLNLRPKNLADDRATTLEVMAYHMKELELKDEDIACCLYGASVFLQKKHLKNAFE
HCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHH
TLKQNQNTDYVFTCSPFSASPYRSFSLENGVQMAFKEHSNTRTQDLKTLYHDAGLLYMGK
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCEEEECH
AQAFKEMRPIFSPNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNACQ
HHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAIAIVLARSSSKRIKNKNIIDFFNKPMLAYPIEAALNSKLFEKVFISSDSMEYVNLAK
CCEEEEEEECCCCHHHCCCCHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCCHHHHHHHH
NYGASFLNLRPKNLADDRATTLEVMAYHMKELELKDEDIACCLYGASVFLQKKHLKNAFE
HCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHH
TLKQNQNTDYVFTCSPFSASPYRSFSLENGVQMAFKEHSNTRTQDLKTLYHDAGLLYMGK
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCEEEECH
AQAFKEMRPIFSPNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNACQ
HHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2549035 [H]