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The map label for this gene is 108562755

Identifier: 108562755

GI number: 108562755

Start: 341632

End: 342507

Strand: Direct

Name: 108562755

Synonym: HPAG1_0330

Alternate gene names: NA

Gene position: 341632-342507 (Clockwise)

Preceding gene: 108562754

Following gene: 108562756

Centisome position: 21.4

GC content: 36.64

Gene sequence:

>876_bases
ATGCCAGTAAAAATTTTGTGCGATTGTTTTTTAACAAGCGGTTTAGGGCATGTGAGGCGTTGTGAAAAAATCCTTTCTTT
TATAGAAAAATTAGGAGTTAAAGTGGATCTTTATTCACACAAGCAAAATAATATAAGCGCTTTTTTAGAGGGTGTTGGCA
ATGATGATTTTTTGATTACAGACAGCTATTGTTTAAATTCAAAGGATTTTTATCTTTTAAAAGAAAAAGCCAAAAGCCTT
ATGGTGATAGAAGATGAAGAGCATGCTAAGGGGTTTTACCCTAAAAATACTAAGATCATGAATTTCACGCTGAACGCCTT
AAAACACTATAACCATGCGTCTAAAGATCATTATTTGGGGGTGGGGTTTTACCCTGTTGATATTCGCTTTGTCTATGAGC
GCCCTATTAATACAGAAAATAAAGAAGTGCTGATCACTCTAGGGGGGAGCGAGCAAAAAACGCTCAAAACGCTCAAAGAG
ATAGTCAAAATTTTAGAAAATAAGGGCATGCATTTGCATATCATTTCACCTCATACCCCTAAAAATCCTCCCAAAAACAC
GCATTATTACAGCCCTTTAAGCCCTTTAGAGTTCAGTTCTTTGATGAAATTTTGCGCTTGCGCCATTAGCGCTGCAGGCC
AAACCCTCTATGAATTGGCCCTTTCTCAAACGCCCTCTCTTATCCTTCCCATCGCTTCTAATCAAATCATTCAAAGCCAA
GAATTTGAAAATTCAGGCATCTTCAAACAAACGAGTTTAAAAACTTTAGCTAGAGATTTTGAAAAATTACAAATTCAAAA
AAATCAAGCTTGGGCAAAAACCCTAGCCTTTGGGAGTGAATTAGAGAGCGCATTAAGGGAGTTTTTAGAGATTTGA

Upstream 100 bases:

>100_bases
ATTCCATCGCTTTAGAATTATCGCCCTTAGAAGTCCAAGACATTGACACTTTAGAAGATTTAGAATTAGCCAAGCTCAAA
TACAGCCGTTTGAAAAACGC

Downstream 100 bases:

>100_bases
AAAAAAATTATTCTTATGGAAATATCCAAGCGATTGATTTTACTAATTTAAACGATGGAGAAAAGTTGTTGGTTTTAGAA
TTTCGCAACCACCCAAACAC

Product: CMP-N-acetylneuraminic acid synthetase

Products: diphosphate; CMP-N-acylneuraminate

Alternate protein names: FlmD Protein; CMP-Sialic Acid Synthetase NeuA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MPVKILCDCFLTSGLGHVRRCEKILSFIEKLGVKVDLYSHKQNNISAFLEGVGNDDFLITDSYCLNSKDFYLLKEKAKSL
MVIEDEEHAKGFYPKNTKIMNFTLNALKHYNHASKDHYLGVGFYPVDIRFVYERPINTENKEVLITLGGSEQKTLKTLKE
IVKILENKGMHLHIISPHTPKNPPKNTHYYSPLSPLEFSSLMKFCACAISAAGQTLYELALSQTPSLILPIASNQIIQSQ
EFENSGIFKQTSLKTLARDFEKLQIQKNQAWAKTLAFGSELESALREFLEI

Sequences:

>Translated_291_residues
MPVKILCDCFLTSGLGHVRRCEKILSFIEKLGVKVDLYSHKQNNISAFLEGVGNDDFLITDSYCLNSKDFYLLKEKAKSL
MVIEDEEHAKGFYPKNTKIMNFTLNALKHYNHASKDHYLGVGFYPVDIRFVYERPINTENKEVLITLGGSEQKTLKTLKE
IVKILENKGMHLHIISPHTPKNPPKNTHYYSPLSPLEFSSLMKFCACAISAAGQTLYELALSQTPSLILPIASNQIIQSQ
EFENSGIFKQTSLKTLARDFEKLQIQKNQAWAKTLAFGSELESALREFLEI
>Mature_290_residues
PVKILCDCFLTSGLGHVRRCEKILSFIEKLGVKVDLYSHKQNNISAFLEGVGNDDFLITDSYCLNSKDFYLLKEKAKSLM
VIEDEEHAKGFYPKNTKIMNFTLNALKHYNHASKDHYLGVGFYPVDIRFVYERPINTENKEVLITLGGSEQKTLKTLKEI
VKILENKGMHLHIISPHTPKNPPKNTHYYSPLSPLEFSSLMKFCACAISAAGQTLYELALSQTPSLILPIASNQIIQSQE
FENSGIFKQTSLKTLARDFEKLQIQKNQAWAKTLAFGSELESALREFLEI

Specific function: Unknown

COG id: COG3980

COG function: function code M; Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.43

Molecular weight: Translated: 33028; Mature: 32896

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVKILCDCFLTSGLGHVRRCEKILSFIEKLGVKVDLYSHKQNNISAFLEGVGNDDFLIT
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHCCCCCCEEEE
DSYCLNSKDFYLLKEKAKSLMVIEDEEHAKGFYPKNTKIMNFTLNALKHYNHASKDHYLG
CCEEECCCCEEEEECCCCCEEEEECCHHCCCCCCCCCEEEEHHHHHHHHCCCCCCCCEEE
VGFYPVDIRFVYERPINTENKEVLITLGGSEQKTLKTLKEIVKILENKGMHLHIISPHTP
EEEEEEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCC
KNPPKNTHYYSPLSPLEFSSLMKFCACAISAAGQTLYELALSQTPSLILPIASNQIIQSQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHCC
EFENSGIFKQTSLKTLARDFEKLQIQKNQAWAKTLAFGSELESALREFLEI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVKILCDCFLTSGLGHVRRCEKILSFIEKLGVKVDLYSHKQNNISAFLEGVGNDDFLIT
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHCCCCCCEEEE
DSYCLNSKDFYLLKEKAKSLMVIEDEEHAKGFYPKNTKIMNFTLNALKHYNHASKDHYLG
CCEEECCCCEEEEECCCCCEEEEECCHHCCCCCCCCCEEEEHHHHHHHHCCCCCCCCEEE
VGFYPVDIRFVYERPINTENKEVLITLGGSEQKTLKTLKEIVKILENKGMHLHIISPHTP
EEEEEEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCC
KNPPKNTHYYSPLSPLEFSSLMKFCACAISAAGQTLYELALSQTPSLILPIASNQIIQSQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHCC
EFENSGIFKQTSLKTLARDFEKLQIQKNQAWAKTLAFGSELESALREFLEI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; N-acylneuraminate

Specific reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA