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The map label for this gene is hisS [H]

Identifier: 103488192

GI number: 103488192

Start: 2862577

End: 2863872

Strand: Reverse

Name: hisS [H]

Synonym: Sala_2715

Alternate gene names: 103488192

Gene position: 2863872-2862577 (Counterclockwise)

Preceding gene: 103488194

Following gene: 103488191

Centisome position: 85.61

GC content: 63.35

Gene sequence:

>1296_bases
TTGCGCTCTCCCCAAAATCGACTAGACGCCGCCGCCATGAGCAAGGACAAGCCCGCCAGAATCCCGACGCCGCAGCCGGT
GCGCGGCACGCAGGACATGCTCGGCGATTTCGCCGACCGCTTCGCGCATGTCGTCGAGACGTTCGAGCGCGTGCGCCGCC
TCTATGGTTTCAAGCGCGTCGAGGTGCCGGTGATCGAGCCGACCGCGGTGTTCGCGCGCTCCTTGGGCGAGACGACCGAT
GTCGTGTCGAAGGAAATGTATTCGTTCGACGATCGCGGCGGCGAATCGGTGACGCTGCGCCCCGAATTCACCGCGGGGAT
CGCGCGCGCCTACATCACCAACGGCTGGCAGCAATATGCTCCGCTCAAGGTCGCGACGCACGGGCCGCTGTTCCGTTACG
AGCGGCCGCAAAAGGGACGCTATCGCCAGTTTCACCAATTGGACGCCGAAGTGCTGGGCAGCGACAGCCCGCTCGCCGAT
GCCGAACTGCTGGTGTTCGCCGATCAATTGCTGAAGGAGCTTGGGATCGCCGAGGGCGTGACCTTGACGCTTAATACGCT
GGGCGATGCGGAAAGCCGCGACGCCTGGCGCGCGGCGCTGGTCGAGCATTTCGAAGCGCATCGCGGGGAGCTGTCGGAAG
ACAGCCTCGCCCGGCTCGACAAGAATCCGCTCCGCATTCTGGACAGCAAAGACCCGCGCGACCGCCCGATCGCCGACAGC
GCGCCCGACATCGATGCGTTTCTGACCGGCGAAGCACAGGATTTCTTCGGTGCCGTGACCGCGGGGCTCGATGCCGCGGG
CGTGGCATGGGAGCGCAACGCGCGGCTGGTGCGCGGACTCGACTATTATCGCCACACCGCGTTCGAATTCGTCACCGATC
GGCTGGGGGCGCAGGGCACCGTGCTCGGCGGCGGTCGTTATGACGGGCTGATCGAAGCGCTCGGCGGGCCACCGACCGCG
GCGGTCGGCTGGGCAGCGGGGATCGAGCGGCTGGCGATGTTGGTGGAAGGAAGCTCTTGGGCAGAGCCGCTGGTAGTAAG
CATTGCCGTGGAAGATGATCGGCTGATTAATGAGGGCATGCGAGCCAATGCTGCCATTCGTCGAGCAGGCTTTTCGACGG
AGATGGTCGCCACTGGTTCGCCGAAGAAGCGATATGATCGTGCCGCGAAAATCTGGGCGAAGGTGCTTCTCTCTTTTTCG
ATCCGGAACGATCAAACCATTCTAAACCTCCGTTCTGCTCCGGGAACACCTGAGCATCAGGCCATTCTTGATATTCTGGA
ATCACTCAAAAAGTGA

Upstream 100 bases:

>100_bases
TCGGCCTTGCGCAAGGCCGATGGCCCCCACCCGCTGCGACTGAGCCAGCAAGCTGGCAAGTCTCGCTGCCCTCCCCTGAA
GGAGAGGGCTTTGTAGCCCT

Downstream 100 bases:

>100_bases
CCTTGATCGCTATCCGACAGATCGATGCGCACTTTAAGCCCCTCCCCTTCAGGGGAGGGGTTGGGGTGGGGGCCATCGGC
CTTGCGCAAGGCCGATGGCC

Product: histidyl-tRNA synthetase

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MRSPQNRLDAAAMSKDKPARIPTPQPVRGTQDMLGDFADRFAHVVETFERVRRLYGFKRVEVPVIEPTAVFARSLGETTD
VVSKEMYSFDDRGGESVTLRPEFTAGIARAYITNGWQQYAPLKVATHGPLFRYERPQKGRYRQFHQLDAEVLGSDSPLAD
AELLVFADQLLKELGIAEGVTLTLNTLGDAESRDAWRAALVEHFEAHRGELSEDSLARLDKNPLRILDSKDPRDRPIADS
APDIDAFLTGEAQDFFGAVTAGLDAAGVAWERNARLVRGLDYYRHTAFEFVTDRLGAQGTVLGGGRYDGLIEALGGPPTA
AVGWAAGIERLAMLVEGSSWAEPLVVSIAVEDDRLINEGMRANAAIRRAGFSTEMVATGSPKKRYDRAAKIWAKVLLSFS
IRNDQTILNLRSAPGTPEHQAILDILESLKK

Sequences:

>Translated_431_residues
MRSPQNRLDAAAMSKDKPARIPTPQPVRGTQDMLGDFADRFAHVVETFERVRRLYGFKRVEVPVIEPTAVFARSLGETTD
VVSKEMYSFDDRGGESVTLRPEFTAGIARAYITNGWQQYAPLKVATHGPLFRYERPQKGRYRQFHQLDAEVLGSDSPLAD
AELLVFADQLLKELGIAEGVTLTLNTLGDAESRDAWRAALVEHFEAHRGELSEDSLARLDKNPLRILDSKDPRDRPIADS
APDIDAFLTGEAQDFFGAVTAGLDAAGVAWERNARLVRGLDYYRHTAFEFVTDRLGAQGTVLGGGRYDGLIEALGGPPTA
AVGWAAGIERLAMLVEGSSWAEPLVVSIAVEDDRLINEGMRANAAIRRAGFSTEMVATGSPKKRYDRAAKIWAKVLLSFS
IRNDQTILNLRSAPGTPEHQAILDILESLKK
>Mature_431_residues
MRSPQNRLDAAAMSKDKPARIPTPQPVRGTQDMLGDFADRFAHVVETFERVRRLYGFKRVEVPVIEPTAVFARSLGETTD
VVSKEMYSFDDRGGESVTLRPEFTAGIARAYITNGWQQYAPLKVATHGPLFRYERPQKGRYRQFHQLDAEVLGSDSPLAD
AELLVFADQLLKELGIAEGVTLTLNTLGDAESRDAWRAALVEHFEAHRGELSEDSLARLDKNPLRILDSKDPRDRPIADS
APDIDAFLTGEAQDFFGAVTAGLDAAGVAWERNARLVRGLDYYRHTAFEFVTDRLGAQGTVLGGGRYDGLIEALGGPPTA
AVGWAAGIERLAMLVEGSSWAEPLVVSIAVEDDRLINEGMRANAAIRRAGFSTEMVATGSPKKRYDRAAKIWAKVLLSFS
IRNDQTILNLRSAPGTPEHQAILDILESLKK

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788861, Length=312, Percent_Identity=48.0769230769231, Blast_Score=300, Evalue=9e-83,
Organism=Caenorhabditis elegans, GI71993686, Length=400, Percent_Identity=27, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71993693, Length=400, Percent_Identity=27, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516 [H]

Pfam domain/function: PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.21 [H]

Molecular weight: Translated: 47449; Mature: 47449

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPQNRLDAAAMSKDKPARIPTPQPVRGTQDMLGDFADRFAHVVETFERVRRLYGFKRV
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
EVPVIEPTAVFARSLGETTDVVSKEMYSFDDRGGESVTLRPEFTAGIARAYITNGWQQYA
ECEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCHHHHC
PLKVATHGPLFRYERPQKGRYRQFHQLDAEVLGSDSPLADAELLVFADQLLKELGIAEGV
CEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TLTLNTLGDAESRDAWRAALVEHFEAHRGELSEDSLARLDKNPLRILDSKDPRDRPIADS
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCCC
APDIDAFLTGEAQDFFGAVTAGLDAAGVAWERNARLVRGLDYYRHTAFEFVTDRLGAQGT
CCCCCEEECCCHHHHHHHHHHCCCHHCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
VLGGGRYDGLIEALGGPPTAAVGWAAGIERLAMLVEGSSWAEPLVVSIAVEDDRLINEGM
EECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHCCH
RANAAIRRAGFSTEMVATGSPKKRYDRAAKIWAKVLLSFSIRNDQTILNLRSAPGTPEHQ
HHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
AILDILESLKK
HHHHHHHHHCC
>Mature Secondary Structure
MRSPQNRLDAAAMSKDKPARIPTPQPVRGTQDMLGDFADRFAHVVETFERVRRLYGFKRV
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
EVPVIEPTAVFARSLGETTDVVSKEMYSFDDRGGESVTLRPEFTAGIARAYITNGWQQYA
ECEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCHHHHC
PLKVATHGPLFRYERPQKGRYRQFHQLDAEVLGSDSPLADAELLVFADQLLKELGIAEGV
CEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TLTLNTLGDAESRDAWRAALVEHFEAHRGELSEDSLARLDKNPLRILDSKDPRDRPIADS
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCCC
APDIDAFLTGEAQDFFGAVTAGLDAAGVAWERNARLVRGLDYYRHTAFEFVTDRLGAQGT
CCCCCEEECCCHHHHHHHHHHCCCHHCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
VLGGGRYDGLIEALGGPPTAAVGWAAGIERLAMLVEGSSWAEPLVVSIAVEDDRLINEGM
EECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHCCH
RANAAIRRAGFSTEMVATGSPKKRYDRAAKIWAKVLLSFSIRNDQTILNLRSAPGTPEHQ
HHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
AILDILESLKK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA