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The map label for this gene is ycdF [H]

Identifier: 103487596

GI number: 103487596

Start: 2221824

End: 2222585

Strand: Direct

Name: ycdF [H]

Synonym: Sala_2115

Alternate gene names: 103487596

Gene position: 2221824-2222585 (Clockwise)

Preceding gene: 103487595

Following gene: 103487599

Centisome position: 66.42

GC content: 72.05

Gene sequence:

>762_bases
ATGACGCAAAAGCTCGCTCTCGTCACGGGCGGGCTCCACCGCGTCGGCGCCGCGATTTCGGCGCGGCTCGCGCGCGAGGG
CTATGCGCTGGCGATCCACAAGCGCAGCCCCGGCGAGGCCGACCCGGTGCTGGCCGAAGCACTCGCCGAGACCGGCGCGG
TCAGCCATCGCTTTGCCGCCGACCTGTCCGATCCGGCGGCGGTCGAGGCGCTGGTCCCCGCAGTGATCGAACGATTCGGC
CGCGCGCCCGACCTGCTCGTCAACAATGCGGCGCTGTTCGCCGAGGGCGAATGGGCCGACCTGTCGGCGGCTGCGCTCGC
CGAAATGATGCAGGTCAATCACCATGCGCCGGTAATGCTCGCCAGGGCGCTCGTCGCGGCGAGCGAGGGCAGGCGCCCCG
CGATCGTCAATATCGTCGATCAGCGCGTCGCGCATCCGGTGCCCGACCAGATCGCCTACAGCCTGTCGAAAGCGGCGCTG
TGGCAGGCGACGGCGACGCTGGCGGTCGCGTTCGGCAGCCGCGCGCGCGTCAACGCCGTCGCGCCGGGGCTGACGCTGGC
GACCGGCGATTATTCGGCGGCGCAGGTCGAACGGCTGGCAAAGCGGATGCCGCTGGGCGCGCTGCCGACCCCCGCCGAGG
TCGCCGACGCGGTCGCCTGGCTCGCGCGCGCCGAGGCGGTGACAGGGCAGACGATCTTTGTCGACGGCGGCGCGCATCTG
GCGCCGCTGGGACGCGATTTTGTGGCGCTGGACCGGGATTGA

Upstream 100 bases:

>100_bases
TGCAGGACGACAAGGTCGAGGAGGTCGAGGTCAAGATCGTCAAGCTGGCGATCGCCGAAGAAGGCGAAGAGATCGGGATC
ACCATGCGGCGGGTTCGCAA

Downstream 100 bases:

>100_bases
GCGTTGCTGGCTGACGTTGGCCGGTTTCGACCAACAGCAGCCATTTCTATCGTCGTCATCCCGGCGAAGGCCGGGATCTC
ACCCTCTCGTCCTGACGCAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: GLCDH-II; GDH-II; General stress protein 74; GSP74 [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTQKLALVTGGLHRVGAAISARLAREGYALAIHKRSPGEADPVLAEALAETGAVSHRFAADLSDPAAVEALVPAVIERFG
RAPDLLVNNAALFAEGEWADLSAAALAEMMQVNHHAPVMLARALVAASEGRRPAIVNIVDQRVAHPVPDQIAYSLSKAAL
WQATATLAVAFGSRARVNAVAPGLTLATGDYSAAQVERLAKRMPLGALPTPAEVADAVAWLARAEAVTGQTIFVDGGAHL
APLGRDFVALDRD

Sequences:

>Translated_253_residues
MTQKLALVTGGLHRVGAAISARLAREGYALAIHKRSPGEADPVLAEALAETGAVSHRFAADLSDPAAVEALVPAVIERFG
RAPDLLVNNAALFAEGEWADLSAAALAEMMQVNHHAPVMLARALVAASEGRRPAIVNIVDQRVAHPVPDQIAYSLSKAAL
WQATATLAVAFGSRARVNAVAPGLTLATGDYSAAQVERLAKRMPLGALPTPAEVADAVAWLARAEAVTGQTIFVDGGAHL
APLGRDFVALDRD
>Mature_252_residues
TQKLALVTGGLHRVGAAISARLAREGYALAIHKRSPGEADPVLAEALAETGAVSHRFAADLSDPAAVEALVPAVIERFGR
APDLLVNNAALFAEGEWADLSAAALAEMMQVNHHAPVMLARALVAASEGRRPAIVNIVDQRVAHPVPDQIAYSLSKAALW
QATATLAVAFGSRARVNAVAPGLTLATGDYSAAQVERLAKRMPLGALPTPAEVADAVAWLARAEAVTGQTIFVDGGAHLA
PLGRDFVALDRD

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=31.1284046692607, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=28.2157676348548, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=32.295719844358, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=31.2, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=29.6747967479675, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787891, Length=243, Percent_Identity=30.4526748971193, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=33.469387755102, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.5546558704453, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=30.9433962264151, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=30.1526717557252, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=29.7397769516729, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=29.6992481203008, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=268, Percent_Identity=27.2388059701493, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=27.9693486590038, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=27.9245283018868, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=26.0377358490566, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=277, Percent_Identity=29.6028880866426, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=29.4820717131474, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=27.7153558052434, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=27.3408239700375, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=26, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=26.6129032258064, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=28.6792452830189, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30.8, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=25.7352941176471, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=27.5471698113208, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=30.5882352941176, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.8, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644337, Length=248, Percent_Identity=31.4516129032258, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=29.6, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=28.7449392712551, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 26276; Mature: 26145

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKLALVTGGLHRVGAAISARLAREGYALAIHKRSPGEADPVLAEALAETGAVSHRFAA
CCCEEEHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHH
DLSDPAAVEALVPAVIERFGRAPDLLVNNAALFAEGEWADLSAAALAEMMQVNHHAPVML
CCCCHHHHHHHHHHHHHHHCCCCCCEECCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHH
ARALVAASEGRRPAIVNIVDQRVAHPVPDQIAYSLSKAALWQATATLAVAFGSRARVNAV
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
APGLTLATGDYSAAQVERLAKRMPLGALPTPAEVADAVAWLARAEAVTGQTIFVDGGAHL
CCCCEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCEE
APLGRDFVALDRD
CCCCCCEEEECCC
>Mature Secondary Structure 
TQKLALVTGGLHRVGAAISARLAREGYALAIHKRSPGEADPVLAEALAETGAVSHRFAA
CCEEEHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHH
DLSDPAAVEALVPAVIERFGRAPDLLVNNAALFAEGEWADLSAAALAEMMQVNHHAPVML
CCCCHHHHHHHHHHHHHHHCCCCCCEECCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHH
ARALVAASEGRRPAIVNIVDQRVAHPVPDQIAYSLSKAALWQATATLAVAFGSRARVNAV
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
APGLTLATGDYSAAQVERLAKRMPLGALPTPAEVADAVAWLARAEAVTGQTIFVDGGAHL
CCCCEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCEE
APLGRDFVALDRD
CCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9298659 [H]