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The map label for this gene is grp [H]

Identifier: 103487458

GI number: 103487458

Start: 2081872

End: 2082342

Strand: Direct

Name: grp [H]

Synonym: Sala_1974

Alternate gene names: 103487458

Gene position: 2081872-2082342 (Clockwise)

Preceding gene: 103487454

Following gene: 103487460

Centisome position: 62.24

GC content: 61.57

Gene sequence:

>471_bases
ATGGCCGATCTTGATCCCTTTGAGATAAAAATCCTCCGCGAATTGCAGCGCGACGCCAATCAGACGACGGCCGAGATCGC
CGAGCGCGTCGGCCTGTCGGTGTCGCCCTGCTGGCGCCGCATCGACCGGCTCGAACGCGATGGCTTCATCAGGAAACGCG
TCGCGATCGTCGATCGCCGCAAGGTCGGACTCAACGCGCACGTCTTTGCGCAGGTCAGGCTCAACGCGCACGGCCGGGCC
AACCTCGACGAGTTCAGCGCAGCGATCCGGGGTTTTCCCGAAGTGCTCGACGCCTATGTGCTGATGGGCACGACCGATTT
CATGCTGCGCATCGTCGCCCGCGACATCGACGCCTATGAACGCTTTTTCTTCGACCAGCTGAGCAAGCTGCCCGGCATCC
AGGAAATCAACTCGACCGTCGCGCTCTCGGAAATCAAGTCGACGACCGAACTGCCGCTGGGTATCGAATGA

Upstream 100 bases:

>100_bases
CGCTTATCGCATCGTTCGGCAGGGCGTTCTTGATCGCATCTTTATTGTTCGCCGGATTTTCGGGATATTATGTTCGCTCA
TTGCCTGATAAAGGAAACAG

Downstream 100 bases:

>100_bases
CTGCTTGCCGGAAACTTGCGGGAGAACGCCTGCCTTGGCCTGCTCCCGGTGTGGTGGACACCGATAGGGGGAATGAAGCG
CAGGCAAGTGGGGGCCGTAG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MADLDPFEIKILRELQRDANQTTAEIAERVGLSVSPCWRRIDRLERDGFIRKRVAIVDRRKVGLNAHVFAQVRLNAHGRA
NLDEFSAAIRGFPEVLDAYVLMGTTDFMLRIVARDIDAYERFFFDQLSKLPGIQEINSTVALSEIKSTTELPLGIE

Sequences:

>Translated_156_residues
MADLDPFEIKILRELQRDANQTTAEIAERVGLSVSPCWRRIDRLERDGFIRKRVAIVDRRKVGLNAHVFAQVRLNAHGRA
NLDEFSAAIRGFPEVLDAYVLMGTTDFMLRIVARDIDAYERFFFDQLSKLPGIQEINSTVALSEIKSTTELPLGIE
>Mature_155_residues
ADLDPFEIKILRELQRDANQTTAEIAERVGLSVSPCWRRIDRLERDGFIRKRVAIVDRRKVGLNAHVFAQVRLNAHGRAN
LDEFSAAIRGFPEVLDAYVLMGTTDFMLRIVARDIDAYERFFFDQLSKLPGIQEINSTVALSEIKSTTELPLGIE

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=32.6666666666667, Blast_Score=108, Evalue=1e-25,
Organism=Escherichia coli, GI1787116, Length=149, Percent_Identity=31.5436241610738, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17762; Mature: 17630

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLDPFEIKILRELQRDANQTTAEIAERVGLSVSPCWRRIDRLERDGFIRKRVAIVDRR
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
KVGLNAHVFAQVRLNAHGRANLDEFSAAIRGFPEVLDAYVLMGTTDFMLRIVARDIDAYE
HCCCCEEEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RFFFDQLSKLPGIQEINSTVALSEIKSTTELPLGIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADLDPFEIKILRELQRDANQTTAEIAERVGLSVSPCWRRIDRLERDGFIRKRVAIVDRR
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
KVGLNAHVFAQVRLNAHGRANLDEFSAAIRGFPEVLDAYVLMGTTDFMLRIVARDIDAYE
HCCCCEEEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RFFFDQLSKLPGIQEINSTVALSEIKSTTELPLGIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]