Click here to switch to the map view.

The map label for this gene is cpg2 [H]

Identifier: 103487423

GI number: 103487423

Start: 2044332

End: 2045540

Strand: Direct

Name: cpg2 [H]

Synonym: Sala_1939

Alternate gene names: 103487423

Gene position: 2044332-2045540 (Clockwise)

Preceding gene: 103487421

Following gene: 103487424

Centisome position: 61.11

GC content: 67.74

Gene sequence:

>1209_bases
ATGATCCAGTTGACTGCAACCGAACAGGCGACGCTCGACCGCGCGGCCGACGCACCGATGCTGGCGCAGGTCGAACGATG
GGCCGCGATCAACAGCGGCACGGGCAATCTTGCGGGGCTGAAGACGGTCGCGGGGCAGCTTGCCGACGCCTTTGCCGCCT
TACCCGGCGAACTGCGGCTCGTCGCGCCCGATCCGGTCGAGAGCGTCGATGCCGCGGGGCGCGTCAATATCGTCCAGCGC
GGCGAGCACCTGCACCTTCGCGTACGGCCCGACGCGCCCGTGCAATTGCTGCTCACCGGGCACATGGACACGGTGTTCGC
CGCCGACCATCCATTCCAGACACTGACCTGGCTGGAGGATGGCGTGCTCAACGGTCCCGGCACCGCCGACATGAAGGGCG
GGATAGCGGTGATCCTCGCCGCGCTGACCGCGCTCGAAAGCTCGCCACTCGCGGATCGCGTCGGTTATGACGTGATGATC
AACAGCGACGAGGAAACGGGCAGCCACGCCTCCGCGGCGCTGATCGCCGAACTGGCGCGTGGCAAGACCGCCGCGCTCAC
CTACGAACCCGCGCTTCCGGACGGCACGCTCGCAGGGGCGCGGCCGGGCAGCGGCAATTTCAGCATCACCATCCATGGCC
GCAGCGCCCACGCCGGGCGCAACCCGGAGGAGGGGCGCAACGCCCTGGTCGCCGCGGCCGATCTGGCGCTGCGACTGAAC
GCGCTGAAATCGGGAGAGCTAAAAGTCAATCCGGCACGGATCGACGGTGGCGGCCCCAACAATGTCGTGCCCGATCAGGC
GATCCTGCGCGTCAATATGCGTCCGTCGACCCCCGAAGCGATGGGCGGAGCGGAAAGCGCACTGCGCGCCGCAGTGGCTT
CGGTATCAAGAGAGCATGACGTGCATTGCCATATCCACGGCGGTTTCAACCGCCCGCCCAAGCCGCTTGATGCCGCCGCA
ACGCGGCTGTTCGAGCTGGTGCGGACATGCGGTGCGGCGCTGGGCATCGACATTGCGTGGAAAGCGACGGGCGGCGTGTG
CGACGGCAACAACATCGCCGCCTGCGGCATCCCCGTGGTCGATACCATGGGTCCGCGCGGCGGCGCGATCCATTCGTCGG
ACGAGTTTCTGATCACGGGCAGCCTCGCCGAACGCGCGCAGCTGTCGGCGCTGACCATGATGCGACTAGCGGAACGGGGG
ACTGTGTGA

Upstream 100 bases:

>100_bases
GCGCGGCTATCTTGCGGACCAGGGGTGATGAACCACAGCGCAGCGACAAAATCGCGGGCCGGGGGTGCCAAAGCCGCGCG
GCGCTCGCTATAGCCGCTCC

Downstream 100 bases:

>100_bases
ATCATGTGATCCGGGCGGCCAAACCGGGCGACCTGCAAAGCATTTACGAAATGGCGAAACTGACGGGCGGCGGTTTCACC
AACCTGCCCCCCGACAAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MIQLTATEQATLDRAADAPMLAQVERWAAINSGTGNLAGLKTVAGQLADAFAALPGELRLVAPDPVESVDAAGRVNIVQR
GEHLHLRVRPDAPVQLLLTGHMDTVFAADHPFQTLTWLEDGVLNGPGTADMKGGIAVILAALTALESSPLADRVGYDVMI
NSDEETGSHASAALIAELARGKTAALTYEPALPDGTLAGARPGSGNFSITIHGRSAHAGRNPEEGRNALVAAADLALRLN
ALKSGELKVNPARIDGGGPNNVVPDQAILRVNMRPSTPEAMGGAESALRAAVASVSREHDVHCHIHGGFNRPPKPLDAAA
TRLFELVRTCGAALGIDIAWKATGGVCDGNNIAACGIPVVDTMGPRGGAIHSSDEFLITGSLAERAQLSALTMMRLAERG
TV

Sequences:

>Translated_402_residues
MIQLTATEQATLDRAADAPMLAQVERWAAINSGTGNLAGLKTVAGQLADAFAALPGELRLVAPDPVESVDAAGRVNIVQR
GEHLHLRVRPDAPVQLLLTGHMDTVFAADHPFQTLTWLEDGVLNGPGTADMKGGIAVILAALTALESSPLADRVGYDVMI
NSDEETGSHASAALIAELARGKTAALTYEPALPDGTLAGARPGSGNFSITIHGRSAHAGRNPEEGRNALVAAADLALRLN
ALKSGELKVNPARIDGGGPNNVVPDQAILRVNMRPSTPEAMGGAESALRAAVASVSREHDVHCHIHGGFNRPPKPLDAAA
TRLFELVRTCGAALGIDIAWKATGGVCDGNNIAACGIPVVDTMGPRGGAIHSSDEFLITGSLAERAQLSALTMMRLAERG
TV
>Mature_402_residues
MIQLTATEQATLDRAADAPMLAQVERWAAINSGTGNLAGLKTVAGQLADAFAALPGELRLVAPDPVESVDAAGRVNIVQR
GEHLHLRVRPDAPVQLLLTGHMDTVFAADHPFQTLTWLEDGVLNGPGTADMKGGIAVILAALTALESSPLADRVGYDVMI
NSDEETGSHASAALIAELARGKTAALTYEPALPDGTLAGARPGSGNFSITIHGRSAHAGRNPEEGRNALVAAADLALRLN
ALKSGELKVNPARIDGGGPNNVVPDQAILRVNMRPSTPEAMGGAESALRAAVASVSREHDVHCHIHGGFNRPPKPLDAAA
TRLFELVRTCGAALGIDIAWKATGGVCDGNNIAACGIPVVDTMGPRGGAIHSSDEFLITGSLAERAQLSALTMMRLAERG
TV

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 41581; Mature: 41581

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQLTATEQATLDRAADAPMLAQVERWAAINSGTGNLAGLKTVAGQLADAFAALPGELRL
CEEEECCCHHHHHHHCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
VAPDPVESVDAAGRVNIVQRGEHLHLRVRPDAPVQLLLTGHMDTVFAADHPFQTLTWLED
ECCCCHHHHCCCCEEEEEECCCEEEEEECCCCCEEEEEECCCCEEEECCCCCHHHHHHHC
GVLNGPGTADMKGGIAVILAALTALESSPLADRVGYDVMINSDEETGSHASAALIAELAR
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHHHC
GKTAALTYEPALPDGTLAGARPGSGNFSITIHGRSAHAGRNPEEGRNALVAAADLALRLN
CCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCEEEEHHHHHHEEH
ALKSGELKVNPARIDGGGPNNVVPDQAILRVNMRPSTPEAMGGAESALRAAVASVSREHD
HCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCHHCCCHHHHHHHHHHHHCCCCC
VHCHIHGGFNRPPKPLDAAATRLFELVRTCGAALGIDIAWKATGGVCDGNNIAACGIPVV
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEECCCCEEECCCCCE
DTMGPRGGAIHSSDEFLITGSLAERAQLSALTMMRLAERGTV
ECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIQLTATEQATLDRAADAPMLAQVERWAAINSGTGNLAGLKTVAGQLADAFAALPGELRL
CEEEECCCHHHHHHHCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
VAPDPVESVDAAGRVNIVQRGEHLHLRVRPDAPVQLLLTGHMDTVFAADHPFQTLTWLED
ECCCCHHHHCCCCEEEEEECCCEEEEEECCCCCEEEEEECCCCEEEECCCCCHHHHHHHC
GVLNGPGTADMKGGIAVILAALTALESSPLADRVGYDVMINSDEETGSHASAALIAELAR
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHHHC
GKTAALTYEPALPDGTLAGARPGSGNFSITIHGRSAHAGRNPEEGRNALVAAADLALRLN
CCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCEEEEHHHHHHEEH
ALKSGELKVNPARIDGGGPNNVVPDQAILRVNMRPSTPEAMGGAESALRAAVASVSREHD
HCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCHHCCCHHHHHHHHHHHHCCCCC
VHCHIHGGFNRPPKPLDAAATRLFELVRTCGAALGIDIAWKATGGVCDGNNIAACGIPVV
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEECCCCEEECCCCCE
DTMGPRGGAIHSSDEFLITGSLAERAQLSALTMMRLAERGTV
ECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]