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The map label for this gene is rnd [H]

Identifier: 103487237

GI number: 103487237

Start: 1845105

End: 1846292

Strand: Direct

Name: rnd [H]

Synonym: Sala_1752

Alternate gene names: 103487237

Gene position: 1845105-1846292 (Clockwise)

Preceding gene: 103487232

Following gene: 103487242

Centisome position: 55.16

GC content: 64.73

Gene sequence:

>1188_bases
ATGCAAGTCCATCCGTTAATCGATACCAATGCCGCGCTCCTCGAATTTTGCGATCGTGTCAAGGACAGCGATTTCATCGC
CGTCGATACCGAATTCATGCGCGAAAACACCTTCTGGCCCGAACTGTGCCTGATCCAGGTCGCGGATACCGAACATGCCG
CCGCGATCGATCCGATGGCGCAAGGCATGGATTTGAAGCCGCTGCTCGACCTGCTCGTCGACAATGAGGATATGCTGAAG
GTCTTTCACGCCGGGGGGCAGGATGTCGAAATCATCTTCAACCTGACCGGCAAGACGCCGCACCCGATTTTCGACACGCA
GATCGGCCAGATGGCGCTCGGTCAGGCCGAACAGGTCGGCTATTCGAACCTCGTCGAGGCATGGCTGGGCCTCCAGCTCG
ACAAGGGCGCGCGCTTCACCGACTGGAGCCGCCGCCCGCTCGACAAGCGGCAGATCGACTATGCGATCGGCGACGTGACG
CATCTGGCGAAAATCTTTCCGATGATGCTCGACAAGCTGATCAGGACCGGCCGCGGCCACTGGCTCGACGAAGAAATGGA
GAAGCTCGCCGATCCCGCCAATTACAGCGTCGATCCCGACAAGGCGTGGCAGCGGATCAAGATCCCGTCGCGCAAGCCCG
ACGTGCTCGGTCGCCTGCGCGCGCTCGCCGCGTGGCGCGAGCGCGAGGCGCGCAACAAGAATCTGCCGCGCGGCCGCATC
GTCAAGGACGAGACGCTCGCCGACCTCGCCGCGCACCCGCCAAAGGACCAGGACGGGCTGGGCCGCGTCCGCGGGCTGTC
GGCAACGTGGAAAAGCAACGACATCGGCGCGCGGCTGATGGATGCGCTGACGAACGCCAAGCCGCTCGGCAAGGACGATA
TGCCCGACCGCGCGCCGCGCGGGCCGGGGCTGGGCAAGGAGGGCGCACTCGTCGCCGACCTGCTCAAGCTGCTCCTGAAA
ATCCGCGCGCGCGAACTCAACGTCGCGGCGCGACTGATCGCGCGGAGCGACGACCTGGAGGCGCTGGCGGCGGGTTCGCG
CAAGGGCATCCCGATGATGGAGGGCTGGCGCTACGAGGTTTTCGGTCACGCGGCGCTCGACCTCGTCGAAGGCCGCATGG
GCTTTGCGGTGAAGAACGGCAAGCTGGTGATGAGCGAGATCGACGCGGCGGTGGCTGCCGAAACATGA

Upstream 100 bases:

>100_bases
CCGCCCGTCGACAGCAGGATCGGCGATCCCTCGCCGGGCGAGCGCCAGGCCCTCGCAATTTTTCCTGCCCGTTGGTCCCA
ACTAGCTGTATAGGCGCGCT

Downstream 100 bases:

>100_bases
GCCGGTGATGACATAAACATCGCTTCCGCAGGCGGGGGCGACGAAGACCTCTAAACTAAAGCAGCACCAGTTCGGGTTTT
GCGCCCAGCGCCTGCGCGAG

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQVHPLIDTNAALLEFCDRVKDSDFIAVDTEFMRENTFWPELCLIQVADTEHAAAIDPMAQGMDLKPLLDLLVDNEDMLK
VFHAGGQDVEIIFNLTGKTPHPIFDTQIGQMALGQAEQVGYSNLVEAWLGLQLDKGARFTDWSRRPLDKRQIDYAIGDVT
HLAKIFPMMLDKLIRTGRGHWLDEEMEKLADPANYSVDPDKAWQRIKIPSRKPDVLGRLRALAAWREREARNKNLPRGRI
VKDETLADLAAHPPKDQDGLGRVRGLSATWKSNDIGARLMDALTNAKPLGKDDMPDRAPRGPGLGKEGALVADLLKLLLK
IRARELNVAARLIARSDDLEALAAGSRKGIPMMEGWRYEVFGHAALDLVEGRMGFAVKNGKLVMSEIDAAVAAET

Sequences:

>Translated_395_residues
MQVHPLIDTNAALLEFCDRVKDSDFIAVDTEFMRENTFWPELCLIQVADTEHAAAIDPMAQGMDLKPLLDLLVDNEDMLK
VFHAGGQDVEIIFNLTGKTPHPIFDTQIGQMALGQAEQVGYSNLVEAWLGLQLDKGARFTDWSRRPLDKRQIDYAIGDVT
HLAKIFPMMLDKLIRTGRGHWLDEEMEKLADPANYSVDPDKAWQRIKIPSRKPDVLGRLRALAAWREREARNKNLPRGRI
VKDETLADLAAHPPKDQDGLGRVRGLSATWKSNDIGARLMDALTNAKPLGKDDMPDRAPRGPGLGKEGALVADLLKLLLK
IRARELNVAARLIARSDDLEALAAGSRKGIPMMEGWRYEVFGHAALDLVEGRMGFAVKNGKLVMSEIDAAVAAET
>Mature_395_residues
MQVHPLIDTNAALLEFCDRVKDSDFIAVDTEFMRENTFWPELCLIQVADTEHAAAIDPMAQGMDLKPLLDLLVDNEDMLK
VFHAGGQDVEIIFNLTGKTPHPIFDTQIGQMALGQAEQVGYSNLVEAWLGLQLDKGARFTDWSRRPLDKRQIDYAIGDVT
HLAKIFPMMLDKLIRTGRGHWLDEEMEKLADPANYSVDPDKAWQRIKIPSRKPDVLGRLRALAAWREREARNKNLPRGRI
VKDETLADLAAHPPKDQDGLGRVRGLSATWKSNDIGARLMDALTNAKPLGKDDMPDRAPRGPGLGKEGALVADLLKLLLK
IRARELNVAARLIARSDDLEALAAGSRKGIPMMEGWRYEVFGHAALDLVEGRMGFAVKNGKLVMSEIDAAVAAET

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=386, Percent_Identity=31.3471502590674, Blast_Score=152, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6324574, Length=311, Percent_Identity=24.4372990353698, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161078302, Length=283, Percent_Identity=22.6148409893993, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 43893; Mature: 43893

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVHPLIDTNAALLEFCDRVKDSDFIAVDTEFMRENTFWPELCLIQVADTEHAAAIDPMA
CCCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHHCCCCCCCEEEEEEECCCCHHHHCHHH
QGMDLKPLLDLLVDNEDMLKVFHAGGQDVEIIFNLTGKTPHPIFDTQIGQMALGQAEQVG
CCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCHHHCC
YSNLVEAWLGLQLDKGARFTDWSRRPLDKRQIDYAIGDVTHLAKIFPMMLDKLIRTGRGH
HHHHHHHHHCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WLDEEMEKLADPANYSVDPDKAWQRIKIPSRKPDVLGRLRALAAWREREARNKNLPRGRI
CCHHHHHHHCCCCCCCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VKDETLADLAAHPPKDQDGLGRVRGLSATWKSNDIGARLMDALTNAKPLGKDDMPDRAPR
ECHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
GPGLGKEGALVADLLKLLLKIRARELNVAARLIARSDDLEALAAGSRKGIPMMEGWRYEV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCEEEE
FGHAALDLVEGRMGFAVKNGKLVMSEIDAAVAAET
HHHHHHHHHHCCCCEEEECCEEEHHHHHHHHHCCC
>Mature Secondary Structure
MQVHPLIDTNAALLEFCDRVKDSDFIAVDTEFMRENTFWPELCLIQVADTEHAAAIDPMA
CCCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHHCCCCCCCEEEEEEECCCCHHHHCHHH
QGMDLKPLLDLLVDNEDMLKVFHAGGQDVEIIFNLTGKTPHPIFDTQIGQMALGQAEQVG
CCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCHHHCC
YSNLVEAWLGLQLDKGARFTDWSRRPLDKRQIDYAIGDVTHLAKIFPMMLDKLIRTGRGH
HHHHHHHHHCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WLDEEMEKLADPANYSVDPDKAWQRIKIPSRKPDVLGRLRALAAWREREARNKNLPRGRI
CCHHHHHHHCCCCCCCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VKDETLADLAAHPPKDQDGLGRVRGLSATWKSNDIGARLMDALTNAKPLGKDDMPDRAPR
ECHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
GPGLGKEGALVADLLKLLLKIRARELNVAARLIARSDDLEALAAGSRKGIPMMEGWRYEV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCEEEE
FGHAALDLVEGRMGFAVKNGKLVMSEIDAAVAAET
HHHHHHHHHHCCCCEEEECCEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]