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The map label for this gene is obgE

Identifier: 103487190

GI number: 103487190

Start: 1795038

End: 1796084

Strand: Direct

Name: obgE

Synonym: Sala_1705

Alternate gene names: 103487190

Gene position: 1795038-1796084 (Clockwise)

Preceding gene: 103487187

Following gene: 103487193

Centisome position: 53.66

GC content: 67.24

Gene sequence:

>1047_bases
ATGCACTTTCTCGACCAGGCCAAGATTTTCATCAAGTCGGGCGACGGCGGCCCCGGCGCCGTCAGCTTCCGGCGCGAAAA
ATATATCGAATATGGCGGCCCCGACGGCGGCAATGGCGGCAAGGGCGGCGACATCGTGTTCGAGGCGGTGGCGGGGCTCA
ATACGCTCATCGACTTTCGCTACACCCAGCATTTCAAGGCAAAGCGCGGCACGCCGGGCGCGGGCCGCGACCGCACCGGC
GCGGGCGGCCCCGACCTCGTCATCCAGGTGCCGGTCGGTACGCAGATCCTTGCCGACGACGAGGAACGCACCCTGCTCGC
CGACCTCACCAAAGCGGGCGAGCGCGTCCATTTCCTGCGCGGCGGCGACGGCGGGCGCGGCAATGCCAGCTACAAGACTT
CGACCAACCGCGCGCCGCGCCAGCACGGACCCGGCTGGCCGGGGGAAGAGATGTGGGTGTGGCTGCGGCTCAAGCTGCTC
GCCGACGCGGGCCTCGTCGGCCTCCCCAATGCGGGCAAATCGACCTTCATCAATGCGGTGACCAATGCGCAGGCCAAGGT
CGGCGCCTATGCCTTCACCACGCTCCGCCCGCAATTGGGCGTCGTCAGCCACAAGGGGCATGAGTTCGTCATCGCCGACA
TTCCGGGGCTGATCGAGGGCGCAGCCGAAGGCGCGGGGGTCGGCGACCGTTTCCTCGGCCACATCGAACGCTGCCGCGTG
CTGCTCCACCTCGTCGATGCCAACGATGCCGATGTCGCGACCAGCTACCGCGTCGTTCGCGACGAACTCGAAGCCTATGG
CGCCGACCTGATCGACAAGCCGGTGATCGTCGCGCTCAACAAGATCGACACGCTCGACGACGAATTGATCGCCGCGCTGT
CGGCCGAACTCGAAGCCGAAAGCGGCCATCCCGTGATGGCGCTGTCGGGCGCGAGCGGCGCGGGGATCGAGCCGGTGCTC
GACAAATTGCTCGAAGCGATCGGCCAGCCCGAACCGGGGCCCGATGCCGACGAAGAGGAAAAGGGCGGCGACTGGTCGCC
GATCTGA

Upstream 100 bases:

>100_bases
TTCGCCCTGCGCCGCTTGTAAGCACGGCGGGCGGCAACGCAAGCCGGGCATGGGCTGCGGCGACCTAGCCAAATCGCTGC
GTTCCGACTAAAGGCGCGCG

Downstream 100 bases:

>100_bases
TCCTTCAAAGATTTCGGCCCGTCGCCGCGAAGCCTCACCGCGCCTCGAGAACCATGTTGAACGGCCCCTCGGTCGCGCGC
CGCACGCTGGCGAAACCGCC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MHFLDQAKIFIKSGDGGPGAVSFRREKYIEYGGPDGGNGGKGGDIVFEAVAGLNTLIDFRYTQHFKAKRGTPGAGRDRTG
AGGPDLVIQVPVGTQILADDEERTLLADLTKAGERVHFLRGGDGGRGNASYKTSTNRAPRQHGPGWPGEEMWVWLRLKLL
ADAGLVGLPNAGKSTFINAVTNAQAKVGAYAFTTLRPQLGVVSHKGHEFVIADIPGLIEGAAEGAGVGDRFLGHIERCRV
LLHLVDANDADVATSYRVVRDELEAYGADLIDKPVIVALNKIDTLDDELIAALSAELEAESGHPVMALSGASGAGIEPVL
DKLLEAIGQPEPGPDADEEEKGGDWSPI

Sequences:

>Translated_348_residues
MHFLDQAKIFIKSGDGGPGAVSFRREKYIEYGGPDGGNGGKGGDIVFEAVAGLNTLIDFRYTQHFKAKRGTPGAGRDRTG
AGGPDLVIQVPVGTQILADDEERTLLADLTKAGERVHFLRGGDGGRGNASYKTSTNRAPRQHGPGWPGEEMWVWLRLKLL
ADAGLVGLPNAGKSTFINAVTNAQAKVGAYAFTTLRPQLGVVSHKGHEFVIADIPGLIEGAAEGAGVGDRFLGHIERCRV
LLHLVDANDADVATSYRVVRDELEAYGADLIDKPVIVALNKIDTLDDELIAALSAELEAESGHPVMALSGASGAGIEPVL
DKLLEAIGQPEPGPDADEEEKGGDWSPI
>Mature_348_residues
MHFLDQAKIFIKSGDGGPGAVSFRREKYIEYGGPDGGNGGKGGDIVFEAVAGLNTLIDFRYTQHFKAKRGTPGAGRDRTG
AGGPDLVIQVPVGTQILADDEERTLLADLTKAGERVHFLRGGDGGRGNASYKTSTNRAPRQHGPGWPGEEMWVWLRLKLL
ADAGLVGLPNAGKSTFINAVTNAQAKVGAYAFTTLRPQLGVVSHKGHEFVIADIPGLIEGAAEGAGVGDRFLGHIERCRV
LLHLVDANDADVATSYRVVRDELEAYGADLIDKPVIVALNKIDTLDDELIAALSAELEAESGHPVMALSGASGAGIEPVL
DKLLEAIGQPEPGPDADEEEKGGDWSPI

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=326, Percent_Identity=38.3435582822086, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI111955139, Length=345, Percent_Identity=33.0434782608696, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI111955063, Length=256, Percent_Identity=33.203125, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4758796, Length=148, Percent_Identity=33.1081081081081, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4557537, Length=110, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI58761500, Length=146, Percent_Identity=32.1917808219178, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789574, Length=325, Percent_Identity=51.3846153846154, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1787454, Length=146, Percent_Identity=32.8767123287671, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=335, Percent_Identity=36.4179104477612, Blast_Score=150, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17552324, Length=324, Percent_Identity=32.4074074074074, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=150, Percent_Identity=32, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71981008, Length=114, Percent_Identity=35.0877192982456, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=114, Percent_Identity=34.2105263157895, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=175, Percent_Identity=36.5714285714286, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6319281, Length=122, Percent_Identity=31.9672131147541, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=91, Percent_Identity=34.0659340659341, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=324, Percent_Identity=37.962962962963, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24585318, Length=239, Percent_Identity=38.9121338912134, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI19921908, Length=163, Percent_Identity=30.0613496932515, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640873, Length=108, Percent_Identity=38.8888888888889, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640877, Length=108, Percent_Identity=38.8888888888889, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640875, Length=108, Percent_Identity=38.8888888888889, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17981711, Length=114, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356473, Length=110, Percent_Identity=33.6363636363636, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_SPHAL (Q1GSF4)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616751.1
- ProteinModelPortal:   Q1GSF4
- GeneID:   4081108
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1705
- NMPDR:   fig|317655.9.peg.1637
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- BioCyc:   SALA317655:SALA_1705-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36730; Mature: 36730

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFLDQAKIFIKSGDGGPGAVSFRREKYIEYGGPDGGNGGKGGDIVFEAVAGLNTLIDFR
CCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YTQHFKAKRGTPGAGRDRTGAGGPDLVIQVPVGTQILADDEERTLLADLTKAGERVHFLR
HHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHHCCCEEEEEE
GGDGGRGNASYKTSTNRAPRQHGPGWPGEEMWVWLRLKLLADAGLVGLPNAGKSTFINAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHEEEHHHCCCEEECCCCCHHHHHHHH
TNAQAKVGAYAFTTLRPQLGVVSHKGHEFVIADIPGLIEGAAEGAGVGDRFLGHIERCRV
HCCCHHHCEEEEEECCCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHH
LLHLVDANDADVATSYRVVRDELEAYGADLIDKPVIVALNKIDTLDDELIAALSAELEAE
HHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
SGHPVMALSGASGAGIEPVLDKLLEAIGQPEPGPDADEEEKGGDWSPI
CCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHFLDQAKIFIKSGDGGPGAVSFRREKYIEYGGPDGGNGGKGGDIVFEAVAGLNTLIDFR
CCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YTQHFKAKRGTPGAGRDRTGAGGPDLVIQVPVGTQILADDEERTLLADLTKAGERVHFLR
HHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHHCCCEEEEEE
GGDGGRGNASYKTSTNRAPRQHGPGWPGEEMWVWLRLKLLADAGLVGLPNAGKSTFINAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHEEEHHHCCCEEECCCCCHHHHHHHH
TNAQAKVGAYAFTTLRPQLGVVSHKGHEFVIADIPGLIEGAAEGAGVGDRFLGHIERCRV
HCCCHHHCEEEEEECCCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHH
LLHLVDANDADVATSYRVVRDELEAYGADLIDKPVIVALNKIDTLDDELIAALSAELEAE
HHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
SGHPVMALSGASGAGIEPVLDKLLEAIGQPEPGPDADEEEKGGDWSPI
CCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA