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The map label for this gene is mrdB [H]

Identifier: 103487116

GI number: 103487116

Start: 1711942

End: 1712910

Strand: Direct

Name: mrdB [H]

Synonym: Sala_1631

Alternate gene names: 103487116

Gene position: 1711942-1712910 (Clockwise)

Preceding gene: 103487115

Following gene: 103487119

Centisome position: 51.18

GC content: 63.78

Gene sequence:

>969_bases
GTGCGTTTCCTCGTTTTCCTCGGCGGCGCGCTCGTCCTTGGCCGCCTGCCCCTGCGGATTTTCGAGGATTTTTCCTACCT
TGCCTATATCGGCGTGCTCGTCCTCCTCTTTGCGGTCGAACTGCTGGGCTTCGTCGGCGGCGGCAGCCAGCGATGGCTCA
ACCTCGGCTTCATGAACCTCCAGCCATCGGAGCTGATGAAGGTCGCCATCGTCGTCGCGCTGGCGCGCTTCTATGCCCAG
CTTCCGCCCGCCAGCACGCGCAGCCTTACCGCGCTGTGGCCGGCGCTGGTGATGATCGGGCTTCCGGCGGCACTGGTGAT
GCTGCAACCCGATCTCGGCACCGCGCTGTCGATCTGTGTCGGCGGGGTGATCGTGATGTTCGTCGCGGGCCTGCCGCTCT
GGTGGTTCGGCAGTACGGCAATCGCTGGCGTCGCGGCGCTGCCCATCCTCTTCTCCTTTCTCCACGATTACCAGCAACGG
CGCGTGCTCATCTTCCTCGACCCCGAAAGCGACCCGCTGGGCGCGGGCTATCACATCAGCCAGTCAAAGATCGCGATCGG
ATCGGGCGGGATCGGCGGCAAGGGCTTCCTCAACGGATCGCAAAGCCACCTTGACTATCTTCCCGAAGGGCACACCGATT
TCATCTTTGCGACGATGGCCGAGGAATGGGGGCTGATCGGCGGCCTTGCGCTGCTCTTCGGCTTTTTCCTGCTGCTCCGC
TGGTCGACGCGCGTTGCGCTGAAGGCGCGGACGCGCTTTGGCCAGCTCACCGCCGCGGGGCTGACCATGACGATCTTTTT
CTACATCGCGATCAACCTGATGATGGTGATGGGCCTCGCCCCCGTCGTCGGCATCCCGCTCCCGCTCTTTTCCTATGGCG
GGTCGTCGATGCTGACGATCATGACGTGCATCGGCATCATCCTCGCGATCGAAAACGACAGCAAGACGGGCCCGCGCCGC
TTGCACTGA

Upstream 100 bases:

>100_bases
GAAGCTGATCGCCATCCTGTGCGGTATTACCGGGTTCGGCCTGCTCGTCCTCTATTCGGCCGCGGGTGGCAACTGGTCGC
CCTGGGCGTGGCAACAGGGG

Downstream 100 bases:

>100_bases
CAAAAAATTTCCGCAAGGCCATTGCCAAGGATGCACCGCCATGATAGCGGGCCGCTCTCTTCACGGCGCAGGGGGATTTC
CCCCGCATCGCGAAGGCCGG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRFLVFLGGALVLGRLPLRIFEDFSYLAYIGVLVLLFAVELLGFVGGGSQRWLNLGFMNLQPSELMKVAIVVALARFYAQ
LPPASTRSLTALWPALVMIGLPAALVMLQPDLGTALSICVGGVIVMFVAGLPLWWFGSTAIAGVAALPILFSFLHDYQQR
RVLIFLDPESDPLGAGYHISQSKIAIGSGGIGGKGFLNGSQSHLDYLPEGHTDFIFATMAEEWGLIGGLALLFGFFLLLR
WSTRVALKARTRFGQLTAAGLTMTIFFYIAINLMMVMGLAPVVGIPLPLFSYGGSSMLTIMTCIGIILAIENDSKTGPRR
LH

Sequences:

>Translated_322_residues
MRFLVFLGGALVLGRLPLRIFEDFSYLAYIGVLVLLFAVELLGFVGGGSQRWLNLGFMNLQPSELMKVAIVVALARFYAQ
LPPASTRSLTALWPALVMIGLPAALVMLQPDLGTALSICVGGVIVMFVAGLPLWWFGSTAIAGVAALPILFSFLHDYQQR
RVLIFLDPESDPLGAGYHISQSKIAIGSGGIGGKGFLNGSQSHLDYLPEGHTDFIFATMAEEWGLIGGLALLFGFFLLLR
WSTRVALKARTRFGQLTAAGLTMTIFFYIAINLMMVMGLAPVVGIPLPLFSYGGSSMLTIMTCIGIILAIENDSKTGPRR
LH
>Mature_322_residues
MRFLVFLGGALVLGRLPLRIFEDFSYLAYIGVLVLLFAVELLGFVGGGSQRWLNLGFMNLQPSELMKVAIVVALARFYAQ
LPPASTRSLTALWPALVMIGLPAALVMLQPDLGTALSICVGGVIVMFVAGLPLWWFGSTAIAGVAALPILFSFLHDYQQR
RVLIFLDPESDPLGAGYHISQSKIAIGSGGIGGKGFLNGSQSHLDYLPEGHTDFIFATMAEEWGLIGGLALLFGFFLLLR
WSTRVALKARTRFGQLTAAGLTMTIFFYIAINLMMVMGLAPVVGIPLPLFSYGGSSMLTIMTCIGIILAIENDSKTGPRR
LH

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=308, Percent_Identity=47.7272727272727, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI1786277, Length=309, Percent_Identity=35.2750809061489, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 34761; Mature: 34761

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLVFLGGALVLGRLPLRIFEDFSYLAYIGVLVLLFAVELLGFVGGGSQRWLNLGFMNL
CEEEEEEHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
QPSELMKVAIVVALARFYAQLPPASTRSLTALWPALVMIGLPAALVMLQPDLGTALSICV
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHHHEEECCCCHHHHHHHH
GGVIVMFVAGLPLWWFGSTAIAGVAALPILFSFLHDYQQRRVLIFLDPESDPLGAGYHIS
HHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEC
QSKIAIGSGGIGGKGFLNGSQSHLDYLPEGHTDFIFATMAEEWGLIGGLALLFGFFLLLR
CCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEHHHHHCHHHHHHHHHHHHHHHH
WSTRVALKARTRFGQLTAAGLTMTIFFYIAINLMMVMGLAPVVGIPLPLFSYGGSSMLTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHH
MTCIGIILAIENDSKTGPRRLH
HHHHHHHEEECCCCCCCCCCCC
>Mature Secondary Structure
MRFLVFLGGALVLGRLPLRIFEDFSYLAYIGVLVLLFAVELLGFVGGGSQRWLNLGFMNL
CEEEEEEHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
QPSELMKVAIVVALARFYAQLPPASTRSLTALWPALVMIGLPAALVMLQPDLGTALSICV
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHHHEEECCCCHHHHHHHH
GGVIVMFVAGLPLWWFGSTAIAGVAALPILFSFLHDYQQRRVLIFLDPESDPLGAGYHIS
HHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEC
QSKIAIGSGGIGGKGFLNGSQSHLDYLPEGHTDFIFATMAEEWGLIGGLALLFGFFLLLR
CCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEHHHHHCHHHHHHHHHHHHHHHH
WSTRVALKARTRFGQLTAAGLTMTIFFYIAINLMMVMGLAPVVGIPLPLFSYGGSSMLTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHH
MTCIGIILAIENDSKTGPRRLH
HHHHHHHEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]