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The map label for this gene is crt [H]

Identifier: 103487119

GI number: 103487119

Start: 1715966

End: 1716766

Strand: Direct

Name: crt [H]

Synonym: Sala_1634

Alternate gene names: 103487119

Gene position: 1715966-1716766 (Clockwise)

Preceding gene: 103487116

Following gene: 103487120

Centisome position: 51.3

GC content: 63.92

Gene sequence:

>801_bases
ATGCAATATGAAACCATCCTGGTCGACGTCGCCGATCATATCGCGACGATCACGCTCAACCGGCCCGAGGCGCTGAACAG
CTTCACGCGGCAGATGATGGCCGAATTCGAGCATCTGTGGAAGCGGGTCGCGCGTGACGACAGCATCCATTGCTGCGTGC
TGCGCGCTGCCCCCGGAAAGGCATGGTGCACCGGCGTCGACGTCAAGGAATCGCAGAAGCCGGGACAGGCGGTCGTCGAT
CTCGATAACATCTGGCATTGCGAAGATCCCGGCATCTATCTCGGCCCCAAGTCGATGAACTGCTGGAAGCCGGTGGTCGC
GGCGGTCCACGGCATGGCGGCTGGCGGCGCCTTTTATTGGCTCAACGAGAGCGACATCATCATCTGCTCCGAAGACGCGA
CTTTCTTCGATCCGCACGTCACCTATGGCATGACGAGCGCACTCGAACCGATCGGCATGACCTATCACATGCCGCTCCAT
GACGTGCTACGCATGGTGCTGCTCGGCAACGACGAGCGGATCGGCGCGGGGACCGCGCTGCGCATCGGGCTGGTCAGCGA
GATCGTGCCGCTGGGCGAGTTGTGGCCGCGCGCACACGAACTCGCCGCCGCCATCGCCGCGAAGCCCCCGGCAGCGACGG
CGGGGTCACTCAAGGCGATCTGGCAATCGCTCGACCTTCCCCGCTCGGTCGCGCTGCAGCAGGCGCTCAAATATTGCCAG
ATCGGCAATCCGGCGGGCGTACCGCAGGTCGACCGCGCCGCCCTGATGGCCGACAAGGCCAAGAAGTTCACCATTCGCTG
A

Upstream 100 bases:

>100_bases
CGAAATTCATCGGAAGGCTTGCCCTGTTGTTGCGATCCGTGTCATAGCGAGTTGTATAACTAGGTCAACCATGACAAACA
CCGGGAAGGAGTCGCTGGCT

Downstream 100 bases:

>100_bases
CGCGATCGGAAGGGAGCGCCGGCCGATGTCGATACTCTATGACGAGGGACAGATTGCGATCGCCGCCGAGTCGCGCCGCA
TATTGGAGGCGCGGGTCAGC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MQYETILVDVADHIATITLNRPEALNSFTRQMMAEFEHLWKRVARDDSIHCCVLRAAPGKAWCTGVDVKESQKPGQAVVD
LDNIWHCEDPGIYLGPKSMNCWKPVVAAVHGMAAGGAFYWLNESDIIICSEDATFFDPHVTYGMTSALEPIGMTYHMPLH
DVLRMVLLGNDERIGAGTALRIGLVSEIVPLGELWPRAHELAAAIAAKPPAATAGSLKAIWQSLDLPRSVALQQALKYCQ
IGNPAGVPQVDRAALMADKAKKFTIR

Sequences:

>Translated_266_residues
MQYETILVDVADHIATITLNRPEALNSFTRQMMAEFEHLWKRVARDDSIHCCVLRAAPGKAWCTGVDVKESQKPGQAVVD
LDNIWHCEDPGIYLGPKSMNCWKPVVAAVHGMAAGGAFYWLNESDIIICSEDATFFDPHVTYGMTSALEPIGMTYHMPLH
DVLRMVLLGNDERIGAGTALRIGLVSEIVPLGELWPRAHELAAAIAAKPPAATAGSLKAIWQSLDLPRSVALQQALKYCQ
IGNPAGVPQVDRAALMADKAKKFTIR
>Mature_266_residues
MQYETILVDVADHIATITLNRPEALNSFTRQMMAEFEHLWKRVARDDSIHCCVLRAAPGKAWCTGVDVKESQKPGQAVVD
LDNIWHCEDPGIYLGPKSMNCWKPVVAAVHGMAAGGAFYWLNESDIIICSEDATFFDPHVTYGMTSALEPIGMTYHMPLH
DVLRMVLLGNDERIGAGTALRIGLVSEIVPLGELWPRAHELAAAIAAKPPAATAGSLKAIWQSLDLPRSVALQQALKYCQ
IGNPAGVPQVDRAALMADKAKKFTIR

Specific function: Catalyzes The Reversible Dehydration Of L-Carnitinyl-CoA To Crotobetainyl-CoA. [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=250, Percent_Identity=29.2, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI221142681, Length=231, Percent_Identity=29.004329004329, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787659, Length=232, Percent_Identity=28.8793103448276, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787660, Length=267, Percent_Identity=28.0898876404494, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87082183, Length=216, Percent_Identity=26.8518518518519, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=229, Percent_Identity=32.7510917030568, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=257, Percent_Identity=24.5136186770428, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129971, Length=266, Percent_Identity=27.4436090225564, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24653477, Length=266, Percent_Identity=27.4436090225564, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 29099; Mature: 29099

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYETILVDVADHIATITLNRPEALNSFTRQMMAEFEHLWKRVARDDSIHCCVLRAAPGK
CCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
AWCTGVDVKESQKPGQAVVDLDNIWHCEDPGIYLGPKSMNCWKPVVAAVHGMAAGGAFYW
CEEECCCCCCCCCCCCEEEECCCEEECCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEE
LNESDIIICSEDATFFDPHVTYGMTSALEPIGMTYHMPLHDVLRMVLLGNDERIGAGTAL
ECCCCEEEECCCCCEECCHHHHCHHHHCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCEE
RIGLVSEIVPLGELWPRAHELAAAIAAKPPAATAGSLKAIWQSLDLPRSVALQQALKYCQ
HHHHHHHHHCHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
IGNPAGVPQVDRAALMADKAKKFTIR
CCCCCCCCCHHHHHHHHHHCHHCCCC
>Mature Secondary Structure
MQYETILVDVADHIATITLNRPEALNSFTRQMMAEFEHLWKRVARDDSIHCCVLRAAPGK
CCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
AWCTGVDVKESQKPGQAVVDLDNIWHCEDPGIYLGPKSMNCWKPVVAAVHGMAAGGAFYW
CEEECCCCCCCCCCCCEEEECCCEEECCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEE
LNESDIIICSEDATFFDPHVTYGMTSALEPIGMTYHMPLHDVLRMVLLGNDERIGAGTAL
ECCCCEEEECCCCCEECCHHHHCHHHHCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCEE
RIGLVSEIVPLGELWPRAHELAAAIAAKPPAATAGSLKAIWQSLDLPRSVALQQALKYCQ
HHHHHHHHHCHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
IGNPAGVPQVDRAALMADKAKKFTIR
CCCCCCCCCHHHHHHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]