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The map label for this gene is gpt

Identifier: 159184890

GI number: 159184890

Start: 1716161

End: 1716658

Strand: Direct

Name: gpt

Synonym: Atu1731

Alternate gene names: 159184890

Gene position: 1716161-1716658 (Clockwise)

Preceding gene: 15889035

Following gene: 15889037

Centisome position: 60.39

GC content: 59.64

Gene sequence:

>498_bases
ATGTCCCTTCCCGATAAAGCCTTTCCCGTCTCCTGGGACCAGTTCCACCGTGATGCCCGTGCACTTGCCTGGCGTCTTGC
CGGTCTCGACAAAGAGTTCCGGGCGATCGTCTGTATTACCCGCGGCGGCCTCGTTCCGGCGGCGATCATTTCCCGCGAAC
TGAACATCCGCATGATCGACACTGTCTGCATCGCCACGCGTCATGACTATGTCAACCAGGGCGACACGGTTCTTTTGAAG
GGCGTGGCCCCGGAACTGACGACCGATGCCGGCGAAGGCGTGCTTGTCGTCGATGATCTCACCGATACCGGCAAGACGGC
GCTGGAAGTGCGCGAAATGCTGCCGAGGGCGCATTTCGCCTGTGTTTACGCCAAGCCGAAGGGCGTGCCGACCATTGACA
CTTTTGTCACTGAAGTCAGCCAGGACACCTGGATTTATTTTCCCTGGGACATGGGCTTCACCTATCAGGAGCCGATCGCC
AAGGGATCGCGCGGCTGA

Upstream 100 bases:

>100_bases
CAATCTCCCGCTCTCGCCTTTACGCGGAACGCTTGCCTTTTTGCCGTTCTTGCGGCTATTAGCCAAAGCCATCGACAATT
TTGACCAGATGGTAGACGAC

Downstream 100 bases:

>100_bases
TTGCCAGTCTCCACTGATATCCGCTCTTAAAAGCCGCCCCACCGAGGGCGGTTTTTTGTGGAGAAACGTCTTTTTTGAAA
GCTGCGGAAAACACGGAAAA

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSLPDKAFPVSWDQFHRDARALAWRLAGLDKEFRAIVCITRGGLVPAAIISRELNIRMIDTVCIATRHDYVNQGDTVLLK
GVAPELTTDAGEGVLVVDDLTDTGKTALEVREMLPRAHFACVYAKPKGVPTIDTFVTEVSQDTWIYFPWDMGFTYQEPIA
KGSRG

Sequences:

>Translated_165_residues
MSLPDKAFPVSWDQFHRDARALAWRLAGLDKEFRAIVCITRGGLVPAAIISRELNIRMIDTVCIATRHDYVNQGDTVLLK
GVAPELTTDAGEGVLVVDDLTDTGKTALEVREMLPRAHFACVYAKPKGVPTIDTFVTEVSQDTWIYFPWDMGFTYQEPIA
KGSRG
>Mature_164_residues
SLPDKAFPVSWDQFHRDARALAWRLAGLDKEFRAIVCITRGGLVPAAIISRELNIRMIDTVCIATRHDYVNQGDTVLLKG
VAPELTTDAGEGVLVVDDLTDTGKTALEVREMLPRAHFACVYAKPKGVPTIDTFVTEVSQDTWIYFPWDMGFTYQEPIAK
GSRG

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily

Homologues:

Organism=Escherichia coli, GI1786433, Length=155, Percent_Identity=45.1612903225806, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XGPT_AGRT5 (Q8UEM6)

Other databases:

- EMBL:   AE007869
- PIR:   AD2789
- PIR:   E97568
- RefSeq:   NP_354717.2
- ProteinModelPortal:   Q8UEM6
- SMR:   Q8UEM6
- STRING:   Q8UEM6
- GeneID:   1133769
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1731
- eggNOG:   COG0503
- HOGENOM:   HBG503428
- OMA:   LVDTFIT
- PhylomeDB:   Q8UEM6
- ProtClustDB:   PRK09177
- BioCyc:   ATUM176299-1:ATU1731-MONOMER
- HAMAP:   MF_01903
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 18328; Mature: 18197

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER; PS00847 MCM_1

Important sites: BINDING 102-102 BINDING 145-145

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPDKAFPVSWDQFHRDARALAWRLAGLDKEFRAIVCITRGGLVPAAIISRELNIRMID
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCCCEEEEE
TVCIATRHDYVNQGDTVLLKGVAPELTTDAGEGVLVVDDLTDTGKTALEVREMLPRAHFA
EEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEE
CVYAKPKGVPTIDTFVTEVSQDTWIYFPWDMGFTYQEPIAKGSRG
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLPDKAFPVSWDQFHRDARALAWRLAGLDKEFRAIVCITRGGLVPAAIISRELNIRMID
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCCCEEEEE
TVCIATRHDYVNQGDTVLLKGVAPELTTDAGEGVLVVDDLTDTGKTALEVREMLPRAHFA
EEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEE
CVYAKPKGVPTIDTFVTEVSQDTWIYFPWDMGFTYQEPIAKGSRG
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194