Click here to switch to the map view.

The map label for this gene is nrdE

Identifier: 15889037

GI number: 15889037

Start: 1717324

End: 1721142

Strand: Direct

Name: nrdE

Synonym: Atu1733

Alternate gene names: 15889037

Gene position: 1717324-1721142 (Clockwise)

Preceding gene: 159184890

Following gene: 159184891

Centisome position: 60.44

GC content: 60.36

Gene sequence:

>3819_bases
ATGCGCATCGAACGCCGCTTCACGAAGCCCGGCCAATCGTCTTACGCGGAAATCGAATTCCGCAAGGCCGTCAGTGAAAT
CAAGAACCCGGATGGTTCCGTCGTGTTCCGTCTGGCGGATATCGACGTTCCCGCGCAGTTCAGCCAGGTTGCGACCGACG
TTCTGGCGCAGAAATACTTCCGCAAGGCCGGTGTGCCGAAGCTGCTGAAGAAGGTTGAGGAAAACGATGTTCCTTCCTTC
CTCTGGCGTTCGGTTGCCGACGAGAAGGCATTGAAGGAACTGCCCGAAGCCGAACGTTATGGCTCCGAGACCGATGCGCG
CCAGGTTTTCGACCGTCTGGCCGGCACCTGGGCCTATTGGGGCTGGAAGGGCAAGTATTTCTCAACCGAAGAAGATGCGT
CCGCCTTCAAGGATGAGCTTGCCTACATGCTCGCAACCCAGCGCGTTGCACCGAACAGCCCGCAATGGTTCAACACCGGC
CTGCACTGGGCCTATGGCATCGATGGCCCCGGCCAGGGGCACTTCTATGTCGACCCCTTCACGGGCAAGCTGACCAAGTC
CAAATCCGCTTACGAACATCCGCAGCCGCATGCCTGCTTCATCCAGTCCGTCGAAGACGATCTGGTCAATGAAGGCGGCA
TCATGGATCTGTGGGTGCGTGAAGCGCGCCTGTTCAAATACGGTTCCGGCACCGGCTCCAACTTCTCCTATCTGCGTGGC
GAAGGCGAAAAGCTTTCCGGCGGCGGCAAGTCCTCCGGCCTGATGAGCTTCCTCAAGATCGGCGACCGCGCAGCCGGCGC
CATCAAGTCCGGCGGCACGACCCGCCGTGCGGCCAAGATGGTCGTCGTTGATGCCGACCATCCCGATATCGAAGCCTATA
TCGACTGGAAGGTGAACGAGGAGCAAAAGGTTGCCGCTCTCGTGACCGGTTCCAAGATCGTTGCCAAGCACCTCAAGGCC
ATCATGAAGGCCTGCGTCAATTGCGAGGCCGACAATGGTGATTGCTTCGACCCGGCCAAGAACCCTGCCCTGAAGCGCGA
AATCCGCGCTGCCAAGAAGGACATGGTGCCGGAAAACTACGTCAAGCGCGTCATCCAGTTCGCCGAACAGGGTTACAAGG
ACATCCAGTTCAAGACCTACGATACGGATTGGGATTCCGAAGCCTATCTTACGGTTTCAGGCCAGAACTCCAACAACTCC
GTATCGCTCAAGGATGACTTCCTGCGCGCTGTCGAAAATGACGGCAACTGGAACCTCACCGCCCGCAAGGACGGCAAGGT
CATGAAAACGCTGAAGGCCCGCGATCTCTGGGAAAAGATTTCCCACGCCGCCTGGGCATCGGCCGATCCGGGCCTGCACT
TCAACACCACCATGAATGACTGGCACACCTCGCCGGCCGAAGGCCCGATCCGCGCTTCCAACCCGTGCTCGGAATATATG
TTCCTTGATGACACGGCCTGCAACCTTGCCTCGCTGAACCTGCTGCAGTTCAAGGATGCCAAGACGAAGCGCATCGATAT
CGCCGATTACGAACATGCCGTGCGCCTGTGGACCGTCGTTCTCGAAGTCTCGGTCATGATGGCGCAGTTCCCGTCCCGCC
AGATTGCCGAACGTTCCTACGAATACCGCACGCTCGGCCTCGGTTACGCCAATATCGGCGGCCTGCTGATGTCCTCGGGC
ATTCCCTATGACAGCGACGAAGGCCGCGCCATTGCAGGTGCGCTGACCGCCATCATGACCGGCGTTTCCTATGCCACCTC
GGCTGAAATGGCCGGCGAGCTTGGCCCCTTCCCGAGCTTTGCGCCGAACCGCGACAACATGCTGCGCGTCATCCGCAACC
ACCGCCGCGCCGCCCATGGCCAATCGGAAGGTTACGAGGGCCTGTCGGTGAACCCGGTTGCCCTCATCCATGCCGATTGC
ACGGATCAGGACCTTGTCGCCCACGCCACGGCCGCCTGGGACAAGGCGCTGGAACTTGGCGAAAAGCACGGTTACCGCAA
CGCCCAGACGACCGTCATCGCGCCGACAGGCACGATCGGCCTCGTGATGGACTGCGACACGACCGGCATCGAGCCCGATT
TCGCGCTGGTGAAGTTCAAGAAGCTCGCCGGCGGCGGTTACTTCAAGATCATCAACCGCGCCGTGCCGGAATCCCTGCGT
TCGCTCGGTTATTCCGAAAGCCAGATCGCCGAGATCGAGGCCTATGCCGTCGGCCATGGCAATCTCAACCAGGCGCCGGC
CATCAATCCCTCGACGCTGAAGGCCAAGGGCTTCACCGATGAGAAGATCGAAGCCGTCAATGCTGCACTGAAAAGCGCCT
TCGACATCAAGTTCGTCTTCAACCAGTGGACGCTCGGCGCTGACTTCCTCAAGGGCACGCTGAAGGTTTCCGACGAGCAG
CTCTCCGACATGAGCTTCAACCTGCTCGACCATCTCGGTTTTGCGAAGAAGGACATCGAAGCGGCAAACGTTCACGTCTG
CGGCGCGATGACGCTGGAAGGCGCGCCGTTCCTGAAGAACGAGCACCTGGCGGTCTTCGACTGCGCCAACCCCTGCGGCA
AGATCGGCAAGCGTTACCTCTCGGTCGAATCGCACATCCGCATGATGGCGGCGGCACAGCCGTTCATCTCCGGCGCGATC
TCCAAGACGATCAACATGCCGAACGATGCGACGGTGGAAGATTGCGGCGCCGCCTACATGCTCTCCTGGAAGCTGGCGCT
GAAGGCCAACGCCCTTTACCGCGACGGTTCCAAGCTTTCCCAGCCGCTCAACGCTTCGCTGGTGGAAGATGAGGACGACG
AAGACTTCGTTGAAGAACTGATCCAGCAGCCGCTTGCCCAGCAGGCCGTGACGATCACCGAGAAGATCGTCGAGCGCGTC
ATCGAGCGTGTATCGCGCGAGCGGGAAAAGCTGCCGAACCGCCGTCAGGGTTACACCCAGAAGGCAACCGTCGGCGGTCA
CAAGGTCTATCTGCGCACCGGCGAATTCGGTGATGGCCGCATCGGCGAAATCTTCATCGACATGCACAAGGAAGGCGCCG
CCTTCCGGGCGATGATGAACAACTTCGCCATCGCCATTTCGCTCGGCCTGCAATATGGCGTGCCGCTGGAAGAATATGTG
GAGGCCTTCACCTTCACCAAGTTCGAACCCGCCGGCATGGTGCAGGGCAACGACGCGATCAAGAACGCCACGTCGATCCT
CGACTACGTGTTCCGCGAACTCGCCGTCTCCTATCTCGGCCGCCATGATCTCGCCCATGTCGATACGTCCGACTTCTCCA
ACACGGCACTCGGCAAGGGTATCCAGGAAGGCAAGACCAACCTGCTCTCCACCGGCTGGACACGCGGTTACAAGCCGACG
CTGGTTTCCAGCAACGAAGGTGACCGCGCCGCTTCCGAGCCCAAGGGTTCGGCAACGGCAGCCCCGGCACGCGGCTCCGC
CAACGTCACCTCCTTTGCCGGCTCCGCCGCCCGCAAGCTGGAACCAACGGTTGCCATCACCACTTCTGAAATCGTCTCCT
TCAAGCGCGATTATGAAGAGCGTGCCAAGGAGCTGGCGGAAGAGATTGCCGAAGAGGTGATCGACGAGGTGGTTCAGGAA
GCCCAGCAGACCGCCACCGCCCTCTTCTCCGACAAGGCCGCCGCCGACGCGGCATCGGCCAAGGCGGAAGCCAAGAAGAA
GGAAAACGAACGCCGCATGCGCTCGATCGCGCAGGGCTATACGGGCAATATGTGCTCGGAATGCCAGAACTTCACAATGG
TGCGGAATGGTACTTGTGAGAAGTGCGATACTTGCGGTGCGACGAGCGGTTGCTCTTGA

Upstream 100 bases:

>100_bases
CCTTACAGATCGGCAACAACCGGCTGCGTGCAGAGTTCGCACGGCTGGAACAGATTTTTGCGCCCTTTGCCGGGCGCCCA
ATGGACGAGGACACGAAACC

Downstream 100 bases:

>100_bases
GAGAAATAAGAGGTCTTCGTCAGATTCACACGAAGAAATAACTAAGAACTGGCCAATAAAAATATTGGCCAGCTCGAAAC
CTAAAATCAGTAAACCAGTA

Product: ribonucleotide-diphosphate reductase subunit alpha

Products: NA

Alternate protein names: Ribonucleoside-diphosphate reductase nrdJ

Number of amino acids: Translated: 1272; Mature: 1272

Protein sequence:

>1272_residues
MRIERRFTKPGQSSYAEIEFRKAVSEIKNPDGSVVFRLADIDVPAQFSQVATDVLAQKYFRKAGVPKLLKKVEENDVPSF
LWRSVADEKALKELPEAERYGSETDARQVFDRLAGTWAYWGWKGKYFSTEEDASAFKDELAYMLATQRVAPNSPQWFNTG
LHWAYGIDGPGQGHFYVDPFTGKLTKSKSAYEHPQPHACFIQSVEDDLVNEGGIMDLWVREARLFKYGSGTGSNFSYLRG
EGEKLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDADHPDIEAYIDWKVNEEQKVAALVTGSKIVAKHLKA
IMKACVNCEADNGDCFDPAKNPALKREIRAAKKDMVPENYVKRVIQFAEQGYKDIQFKTYDTDWDSEAYLTVSGQNSNNS
VSLKDDFLRAVENDGNWNLTARKDGKVMKTLKARDLWEKISHAAWASADPGLHFNTTMNDWHTSPAEGPIRASNPCSEYM
FLDDTACNLASLNLLQFKDAKTKRIDIADYEHAVRLWTVVLEVSVMMAQFPSRQIAERSYEYRTLGLGYANIGGLLMSSG
IPYDSDEGRAIAGALTAIMTGVSYATSAEMAGELGPFPSFAPNRDNMLRVIRNHRRAAHGQSEGYEGLSVNPVALIHADC
TDQDLVAHATAAWDKALELGEKHGYRNAQTTVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINRAVPESLR
SLGYSESQIAEIEAYAVGHGNLNQAPAINPSTLKAKGFTDEKIEAVNAALKSAFDIKFVFNQWTLGADFLKGTLKVSDEQ
LSDMSFNLLDHLGFAKKDIEAANVHVCGAMTLEGAPFLKNEHLAVFDCANPCGKIGKRYLSVESHIRMMAAAQPFISGAI
SKTINMPNDATVEDCGAAYMLSWKLALKANALYRDGSKLSQPLNASLVEDEDDEDFVEELIQQPLAQQAVTITEKIVERV
IERVSREREKLPNRRQGYTQKATVGGHKVYLRTGEFGDGRIGEIFIDMHKEGAAFRAMMNNFAIAISLGLQYGVPLEEYV
EAFTFTKFEPAGMVQGNDAIKNATSILDYVFRELAVSYLGRHDLAHVDTSDFSNTALGKGIQEGKTNLLSTGWTRGYKPT
LVSSNEGDRAASEPKGSATAAPARGSANVTSFAGSAARKLEPTVAITTSEIVSFKRDYEERAKELAEEIAEEVIDEVVQE
AQQTATALFSDKAAADAASAKAEAKKKENERRMRSIAQGYTGNMCSECQNFTMVRNGTCEKCDTCGATSGCS

Sequences:

>Translated_1272_residues
MRIERRFTKPGQSSYAEIEFRKAVSEIKNPDGSVVFRLADIDVPAQFSQVATDVLAQKYFRKAGVPKLLKKVEENDVPSF
LWRSVADEKALKELPEAERYGSETDARQVFDRLAGTWAYWGWKGKYFSTEEDASAFKDELAYMLATQRVAPNSPQWFNTG
LHWAYGIDGPGQGHFYVDPFTGKLTKSKSAYEHPQPHACFIQSVEDDLVNEGGIMDLWVREARLFKYGSGTGSNFSYLRG
EGEKLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDADHPDIEAYIDWKVNEEQKVAALVTGSKIVAKHLKA
IMKACVNCEADNGDCFDPAKNPALKREIRAAKKDMVPENYVKRVIQFAEQGYKDIQFKTYDTDWDSEAYLTVSGQNSNNS
VSLKDDFLRAVENDGNWNLTARKDGKVMKTLKARDLWEKISHAAWASADPGLHFNTTMNDWHTSPAEGPIRASNPCSEYM
FLDDTACNLASLNLLQFKDAKTKRIDIADYEHAVRLWTVVLEVSVMMAQFPSRQIAERSYEYRTLGLGYANIGGLLMSSG
IPYDSDEGRAIAGALTAIMTGVSYATSAEMAGELGPFPSFAPNRDNMLRVIRNHRRAAHGQSEGYEGLSVNPVALIHADC
TDQDLVAHATAAWDKALELGEKHGYRNAQTTVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINRAVPESLR
SLGYSESQIAEIEAYAVGHGNLNQAPAINPSTLKAKGFTDEKIEAVNAALKSAFDIKFVFNQWTLGADFLKGTLKVSDEQ
LSDMSFNLLDHLGFAKKDIEAANVHVCGAMTLEGAPFLKNEHLAVFDCANPCGKIGKRYLSVESHIRMMAAAQPFISGAI
SKTINMPNDATVEDCGAAYMLSWKLALKANALYRDGSKLSQPLNASLVEDEDDEDFVEELIQQPLAQQAVTITEKIVERV
IERVSREREKLPNRRQGYTQKATVGGHKVYLRTGEFGDGRIGEIFIDMHKEGAAFRAMMNNFAIAISLGLQYGVPLEEYV
EAFTFTKFEPAGMVQGNDAIKNATSILDYVFRELAVSYLGRHDLAHVDTSDFSNTALGKGIQEGKTNLLSTGWTRGYKPT
LVSSNEGDRAASEPKGSATAAPARGSANVTSFAGSAARKLEPTVAITTSEIVSFKRDYEERAKELAEEIAEEVIDEVVQE
AQQTATALFSDKAAADAASAKAEAKKKENERRMRSIAQGYTGNMCSECQNFTMVRNGTCEKCDTCGATSGCS
>Mature_1272_residues
MRIERRFTKPGQSSYAEIEFRKAVSEIKNPDGSVVFRLADIDVPAQFSQVATDVLAQKYFRKAGVPKLLKKVEENDVPSF
LWRSVADEKALKELPEAERYGSETDARQVFDRLAGTWAYWGWKGKYFSTEEDASAFKDELAYMLATQRVAPNSPQWFNTG
LHWAYGIDGPGQGHFYVDPFTGKLTKSKSAYEHPQPHACFIQSVEDDLVNEGGIMDLWVREARLFKYGSGTGSNFSYLRG
EGEKLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDADHPDIEAYIDWKVNEEQKVAALVTGSKIVAKHLKA
IMKACVNCEADNGDCFDPAKNPALKREIRAAKKDMVPENYVKRVIQFAEQGYKDIQFKTYDTDWDSEAYLTVSGQNSNNS
VSLKDDFLRAVENDGNWNLTARKDGKVMKTLKARDLWEKISHAAWASADPGLHFNTTMNDWHTSPAEGPIRASNPCSEYM
FLDDTACNLASLNLLQFKDAKTKRIDIADYEHAVRLWTVVLEVSVMMAQFPSRQIAERSYEYRTLGLGYANIGGLLMSSG
IPYDSDEGRAIAGALTAIMTGVSYATSAEMAGELGPFPSFAPNRDNMLRVIRNHRRAAHGQSEGYEGLSVNPVALIHADC
TDQDLVAHATAAWDKALELGEKHGYRNAQTTVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINRAVPESLR
SLGYSESQIAEIEAYAVGHGNLNQAPAINPSTLKAKGFTDEKIEAVNAALKSAFDIKFVFNQWTLGADFLKGTLKVSDEQ
LSDMSFNLLDHLGFAKKDIEAANVHVCGAMTLEGAPFLKNEHLAVFDCANPCGKIGKRYLSVESHIRMMAAAQPFISGAI
SKTINMPNDATVEDCGAAYMLSWKLALKANALYRDGSKLSQPLNASLVEDEDDEDFVEELIQQPLAQQAVTITEKIVERV
IERVSREREKLPNRRQGYTQKATVGGHKVYLRTGEFGDGRIGEIFIDMHKEGAAFRAMMNNFAIAISLGLQYGVPLEEYV
EAFTFTKFEPAGMVQGNDAIKNATSILDYVFRELAVSYLGRHDLAHVDTSDFSNTALGKGIQEGKTNLLSTGWTRGYKPT
LVSSNEGDRAASEPKGSATAAPARGSANVTSFAGSAARKLEPTVAITTSEIVSFKRDYEERAKELAEEIAEEVIDEVVQE
AQQTATALFSDKAAADAASAKAEAKKKENERRMRSIAQGYTGNMCSECQNFTMVRNGTCEKCDTCGATSGCS

Specific function: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen

COG id: COG0209

COG function: function code F; Ribonucleotide reductase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase class-2 family

Homologues:

Organism=Saccharomyces cerevisiae, GI6320914, Length=351, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17352481, Length=346, Percent_Identity=22.2543352601156, Blast_Score=74, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDJ_AGRT5 (Q8UEM4)

Other databases:

- EMBL:   AE007869
- PIR:   AF2789
- PIR:   F97568
- RefSeq:   NP_354718.1
- ProteinModelPortal:   Q8UEM4
- SMR:   Q8UEM4
- STRING:   Q8UEM4
- GeneID:   1139199
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1733
- eggNOG:   COG0209
- HOGENOM:   HBG414188
- OMA:   LDYVFRE
- ProtClustDB:   PRK07562
- BioCyc:   ATUM176299-1:ATU1733-MONOMER
- InterPro:   IPR002876
- InterPro:   IPR017856
- InterPro:   IPR013344
- InterPro:   IPR000788
- InterPro:   IPR013678
- Gene3D:   G3DSA:1.10.10.200
- PANTHER:   PTHR11573
- PRINTS:   PR01183
- TIGRFAMs:   TIGR02504

Pfam domain/function: PF08471 Ribonuc_red_2_N; PF02867 Ribonuc_red_lgC; SSF75625 DUF28

EC number: =1.17.4.1

Molecular weight: Translated: 139624; Mature: 139624

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: ACT_SITE 199-199 ACT_SITE 476-476 ACT_SITE 487-487 ACT_SITE 1265-1265 ACT_SITE 1271-1271

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIERRFTKPGQSSYAEIEFRKAVSEIKNPDGSVVFRLADIDVPAQFSQVATDVLAQKYF
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
RKAGVPKLLKKVEENDVPSFLWRSVADEKALKELPEAERYGSETDARQVFDRLAGTWAYW
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCEEEE
GWKGKYFSTEEDASAFKDELAYMLATQRVAPNSPQWFNTGLHWAYGIDGPGQGHFYVDPF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCEEECCC
TGKLTKSKSAYEHPQPHACFIQSVEDDLVNEGGIMDLWVREARLFKYGSGTGSNFSYLRG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHEECCCCCCCCCEECC
EGEKLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDADHPDIEAYIDWKVNE
CCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEEEECC
EQKVAALVTGSKIVAKHLKAIMKACVNCEADNGDCFDPAKNPALKREIRAAKKDMVPENY
CCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
VKRVIQFAEQGYKDIQFKTYDTDWDSEAYLTVSGQNSNNSVSLKDDFLRAVENDGNWNLT
HHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEHHHHHHHHHCCCCCEEEE
ARKDGKVMKTLKARDLWEKISHAAWASADPGLHFNTTMNDWHTSPAEGPIRASNPCSEYM
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCE
FLDDTACNLASLNLLQFKDAKTKRIDIADYEHAVRLWTVVLEVSVMMAQFPSRQIAERSY
EECCCCCCHHHCCCEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
EYRTLGLGYANIGGLLMSSGIPYDSDEGRAIAGALTAIMTGVSYATSAEMAGELGPFPSF
CEEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APNRDNMLRVIRNHRRAAHGQSEGYEGLSVNPVALIHADCTDQDLVAHATAAWDKALELG
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
EKHGYRNAQTTVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINRAVPESLR
HHCCCCCCCEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
SLGYSESQIAEIEAYAVGHGNLNQAPAINPSTLKAKGFTDEKIEAVNAALKSAFDIKFVF
HCCCCCHHHHEEEEEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCEEEEEE
NQWTLGADFLKGTLKVSDEQLSDMSFNLLDHLGFAKKDIEAANVHVCGAMTLEGAPFLKN
CCCCCCHHHHHHHHEECHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEEEEECCCCCCCC
EHLAVFDCANPCGKIGKRYLSVESHIRMMAAAQPFISGAISKTINMPNDATVEDCGAAYM
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEE
LSWKLALKANALYRDGSKLSQPLNASLVEDEDDEDFVEELIQQPLAQQAVTITEKIVERV
EEEEHEEECCHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERVSREREKLPNRRQGYTQKATVGGHKVYLRTGEFGDGRIGEIFIDMHKEGAAFRAMMN
HHHHHHHHHHCCCHHCCCCCEEECCCEEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHH
NFAIAISLGLQYGVPLEEYVEAFTFTKFEPAGMVQGNDAIKNATSILDYVFRELAVSYLG
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RHDLAHVDTSDFSNTALGKGIQEGKTNLLSTGWTRGYKPTLVSSNEGDRAASEPKGSATA
CCCCCCCCCCCCCCHHHHCCHHHHCHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCC
APARGSANVTSFAGSAARKLEPTVAITTSEIVSFKRDYEERAKELAEEIAEEVIDEVVQE
CCCCCCCCHHHHCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQTATALFSDKAAADAASAKAEAKKKENERRMRSIAQGYTGNMCSECQNFTMVRNGTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEECCCCCC
KCDTCGATSGCS
HHHCCCCCCCCC
>Mature Secondary Structure
MRIERRFTKPGQSSYAEIEFRKAVSEIKNPDGSVVFRLADIDVPAQFSQVATDVLAQKYF
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
RKAGVPKLLKKVEENDVPSFLWRSVADEKALKELPEAERYGSETDARQVFDRLAGTWAYW
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCEEEE
GWKGKYFSTEEDASAFKDELAYMLATQRVAPNSPQWFNTGLHWAYGIDGPGQGHFYVDPF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCEEECCC
TGKLTKSKSAYEHPQPHACFIQSVEDDLVNEGGIMDLWVREARLFKYGSGTGSNFSYLRG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHEECCCCCCCCCEECC
EGEKLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDADHPDIEAYIDWKVNE
CCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEEEECC
EQKVAALVTGSKIVAKHLKAIMKACVNCEADNGDCFDPAKNPALKREIRAAKKDMVPENY
CCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
VKRVIQFAEQGYKDIQFKTYDTDWDSEAYLTVSGQNSNNSVSLKDDFLRAVENDGNWNLT
HHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEHHHHHHHHHCCCCCEEEE
ARKDGKVMKTLKARDLWEKISHAAWASADPGLHFNTTMNDWHTSPAEGPIRASNPCSEYM
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCE
FLDDTACNLASLNLLQFKDAKTKRIDIADYEHAVRLWTVVLEVSVMMAQFPSRQIAERSY
EECCCCCCHHHCCCEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
EYRTLGLGYANIGGLLMSSGIPYDSDEGRAIAGALTAIMTGVSYATSAEMAGELGPFPSF
CEEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APNRDNMLRVIRNHRRAAHGQSEGYEGLSVNPVALIHADCTDQDLVAHATAAWDKALELG
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
EKHGYRNAQTTVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINRAVPESLR
HHCCCCCCCEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
SLGYSESQIAEIEAYAVGHGNLNQAPAINPSTLKAKGFTDEKIEAVNAALKSAFDIKFVF
HCCCCCHHHHEEEEEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCEEEEEE
NQWTLGADFLKGTLKVSDEQLSDMSFNLLDHLGFAKKDIEAANVHVCGAMTLEGAPFLKN
CCCCCCHHHHHHHHEECHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEEEEECCCCCCCC
EHLAVFDCANPCGKIGKRYLSVESHIRMMAAAQPFISGAISKTINMPNDATVEDCGAAYM
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEE
LSWKLALKANALYRDGSKLSQPLNASLVEDEDDEDFVEELIQQPLAQQAVTITEKIVERV
EEEEHEEECCHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERVSREREKLPNRRQGYTQKATVGGHKVYLRTGEFGDGRIGEIFIDMHKEGAAFRAMMN
HHHHHHHHHHCCCHHCCCCCEEECCCEEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHH
NFAIAISLGLQYGVPLEEYVEAFTFTKFEPAGMVQGNDAIKNATSILDYVFRELAVSYLG
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RHDLAHVDTSDFSNTALGKGIQEGKTNLLSTGWTRGYKPTLVSSNEGDRAASEPKGSATA
CCCCCCCCCCCCCCHHHHCCHHHHCHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCC
APARGSANVTSFAGSAARKLEPTVAITTSEIVSFKRDYEERAKELAEEIAEEVIDEVVQE
CCCCCCCCHHHHCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQTATALFSDKAAADAASAKAEAKKKENERRMRSIAQGYTGNMCSECQNFTMVRNGTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEECCCCCC
KCDTCGATSGCS
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194