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The map label for this gene is ribc [H]

Identifier: 159184646

GI number: 159184646

Start: 1163137

End: 1163748

Strand: Direct

Name: ribc [H]

Synonym: Atu1169

Alternate gene names: 159184646

Gene position: 1163137-1163748 (Clockwise)

Preceding gene: 15888505

Following gene: 15888507

Centisome position: 40.93

GC content: 60.62

Gene sequence:

>612_bases
ATGTTTACCGGAATTGTCACCGATGTCGGAACCGTATCCGAGCTGGAAGCGCTGCCGGAGGGTGTTCGCCTGCGCGTGGC
GACCAATTACGATCCGAAGACCATCGATATGGGCGCATCCATTTCCCATGGCGGCGTGTGCCTGACGGTGACGAAGCTGC
CTGATGATGGCAGCAATGAACGCTGGTACGAGGTCGAGGCATGGGAAGAGGCGCTGCGCCTCACCACGATTGCAGGCTGG
AGACAAGGCACGCATGTCAATCTGGAGCGGGCGCTCAAGATCGGCGACGAACTCGGCGGCCACATCGTCTCTGGCCATGT
TGATGGCAGGGCGGAAATCCTGTCGGTTGAGCCGGAAGGCGAAGCGGTGCGCATCCGCCTGCGCGCGCCGGAGCATCTGG
CGAAATTCGTTGCTCCCAAGGGCTCCGTGGCGCTCGACGGTACGTCGCTCACCGTCAATGCTGTTGAAGGCACCGATTTC
GACGTGCTGCTGATCCGTCACACGCTTGCCGTCACCACCTGGGGCGAACGTCAGCCGGGTGATTTCGTTAATTTCGAGGT
CGATACGATGGCCCGTTATGCCGCAAGGCTTGCGGAATTTCCGTCTGCGTAA

Upstream 100 bases:

>100_bases
AAACGCCGCTTCGCCGTGCCGATATCACGGGCGACTATGCTCTTGTCAGCGAAACAGCCTATGGGCCGGATCGCTGCTTC
GATTATGAAAGGCCGATTTG

Downstream 100 bases:

>100_bases
ACCGACAGGGACACGGCGGGTTATAATGCTCGCTGACGCCTCATCCACCCTTCATTCCGGCCCTGAGCCGGAATCCAGCC
AGCCCAAGTCCTTGGGCTGA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MFTGIVTDVGTVSELEALPEGVRLRVATNYDPKTIDMGASISHGGVCLTVTKLPDDGSNERWYEVEAWEEALRLTTIAGW
RQGTHVNLERALKIGDELGGHIVSGHVDGRAEILSVEPEGEAVRIRLRAPEHLAKFVAPKGSVALDGTSLTVNAVEGTDF
DVLLIRHTLAVTTWGERQPGDFVNFEVDTMARYAARLAEFPSA

Sequences:

>Translated_203_residues
MFTGIVTDVGTVSELEALPEGVRLRVATNYDPKTIDMGASISHGGVCLTVTKLPDDGSNERWYEVEAWEEALRLTTIAGW
RQGTHVNLERALKIGDELGGHIVSGHVDGRAEILSVEPEGEAVRIRLRAPEHLAKFVAPKGSVALDGTSLTVNAVEGTDF
DVLLIRHTLAVTTWGERQPGDFVNFEVDTMARYAARLAEFPSA
>Mature_203_residues
MFTGIVTDVGTVSELEALPEGVRLRVATNYDPKTIDMGASISHGGVCLTVTKLPDDGSNERWYEVEAWEEALRLTTIAGW
RQGTHVNLERALKIGDELGGHIVSGHVDGRAEILSVEPEGEAVRIRLRAPEHLAKFVAPKGSVALDGTSLTVNAVEGTDF
DVLLIRHTLAVTTWGERQPGDFVNFEVDTMARYAARLAEFPSA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=191, Percent_Identity=36.1256544502618, Blast_Score=105, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319733, Length=209, Percent_Identity=36.8421052631579, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22036; Mature: 22036

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVTDVGTVSELEALPEGVRLRVATNYDPKTIDMGASISHGGVCLTVTKLPDDGSNE
CCCEEECCCCCHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEEEECCCCCCCC
RWYEVEAWEEALRLTTIAGWRQGTHVNLERALKIGDELGGHIVSGHVDGRAEILSVEPEG
EEEEHHHHHHHHHHHEEECCCCCCEECHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCC
EAVRIRLRAPEHLAKFVAPKGSVALDGTSLTVNAVEGTDFDVLLIRHTLAVTTWGERQPG
CEEEEEEECHHHHHHHHCCCCCEEECCCEEEEEEECCCCEEEEEEEEEEEEEECCCCCCC
DFVNFEVDTMARYAARLAEFPSA
CEEEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIVTDVGTVSELEALPEGVRLRVATNYDPKTIDMGASISHGGVCLTVTKLPDDGSNE
CCCEEECCCCCHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEEEECCCCCCCC
RWYEVEAWEEALRLTTIAGWRQGTHVNLERALKIGDELGGHIVSGHVDGRAEILSVEPEG
EEEEHHHHHHHHHHHEEECCCCCCEECHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCC
EAVRIRLRAPEHLAKFVAPKGSVALDGTSLTVNAVEGTDFDVLLIRHTLAVTTWGERQPG
CEEEEEEECHHHHHHHHCCCCCEEECCCEEEEEEECCCCEEEEEEEEEEEEEECCCCCCC
DFVNFEVDTMARYAARLAEFPSA
CEEEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]